MISAWA Naoaki

写真a

Affiliation

Center for Animal Disease Control

Title

Professor

External Link

Degree 【 display / non-display

  • 農学修士 ( 1983.3   大阪府立大学 )

  • PhD (Veterinary Science) ( 1995.10   The University of Tokyo )

Research Areas 【 display / non-display

  • Life Science / Genome biology

  • Life Science / Bacteriology  / 病原微生物学

  • Life Science / Veterinary medical science  / 人獣共通感染症学

  • Life Science / Food sciences  / 食品衛生学

 

Papers 【 display / non-display

  • Seroprevalence of severe fever with thrombocytopenia syndrome virus in medium-sized wild mammals in Miyazaki, Japan Reviewed International coauthorship

    Kaneko C., Mekata H., Umeki K., Sudaryatma P.E., Irie T., Yamada K., Misawa N., Umekita K., Okabayashi T.

    Ticks and Tick-borne Diseases   14 ( 2 )   2023.3

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Ticks and Tick-borne Diseases  

    Severe fever with thrombocytopenia syndrome (SFTS) is a fatal emerging tick-borne zoonotic disease caused by the SFTS virus (SFTSV). SFTSV infection in humans and companion animals is a matter of concern in endemic areas. Various wild animals are involved in the transmission cycle of SFTSV with vector ticks. Because the home range of medium-sized wild mammals commonly overlaps with humans’ living spheres, this study aimed to reveal the endemicity of SFTSV in such mammals. This study investigated the prevalence of antibodies against SFTSV and viral RNA in medium-sized wild mammals in Miyazaki Prefecture, Japan where human cases have been most frequently reported in Japan and performed a phylogenetic analysis to compare the detected SFTSV with those previously reported. Forty-three of 63 (68%) Japanese badgers (Meles anakuma) and 12 of 53 (23%) Japanese raccoon dogs (Nyctereutes procyonoides viverrinus) had antibodies against SFTSV. Japanese marten (n = 1), weasels (n = 4), and Japanese red fox (n = 1) were negative. Two of 63 (3%) badgers tested positive for SFTSV RNA, whereas the other species were negative. Phylogenetic analysis of the partial nucleotide sequence of SFTSV revealed that viral RNA detected from badgers exhibited 99.8% to 100% similarity to SFTSV, as previously reported in humans, cat, and ticks in the study area. This study demonstrated high seropositivity of antibodies in medium-sized wild mammals and suggested that SFTSV could be shared among these mammals, humans, and companion animals in endemic areas.

    DOI: 10.1016/j.ttbdis.2022.102115

    Scopus

  • Fine Particle Adsorption Capacity of Volcanic Soil from Southern Kyushu, Japan Reviewed International coauthorship

    Misawa N., Yasui K., Sakai K., Kobayashi T., Nagahama H., Haraguchi T., Sasaki S., Torrung V., Luangtongkum T., Taniguchi T., Yamada K., Minamimagari M., Usami T., Kinoshita H.

    Nanomaterials   13 ( 3 )   2023.2

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Nanomaterials  

    “Akahoya” is a volcanic soil classified as a special soil deposited in Kyushu, Japan. Many of its properties are not yet clearly understood. We found that Akahoya had the potential to adsorb bacteria in cattle feces, which prompted us to investigate its material properties and perform experiments to comprehensively evaluate its adsorption performance for various fine particles such as acidic and basic dyes, NOx/SOx gas, and phosphoric acid ions, in addition to bacteria. Akahoya had a very high specific surface area owing to the large number of nanometer-sized pores in its structure; it exhibited a high adsorption capacity for both NO2 and SO2. Regarding the zeta potential of Akahoya, the point of zero charge was approximately pH 7.0. The surface potential had a significant effect on the adsorption of acidic and basic dyes. Akahoya had a very high cation exchange capacity when the sample surface was negatively charged and a high anion exchange capacity when the sample surface was positively charged. Akahoya also exhibited a relatively high adsorption capacity for phosphoric acid because of its high level of Al2O3, and the immersion liquid had a very high Al ion concentration. Finally, filtration tests were performed on Escherichia coli suspension using a column filled with Akahoya or another volcanic soil sample. The results confirmed that the Escherichia coli adhered on the Akahoya sample. The results of the Escherichia coli release test, after the filtration test, suggested that this adhesion to Akahoya could be phosphorus-mediated.

    DOI: 10.3390/nano13030568

    Scopus

  • Comprehensive Analyses of the Bacterial Population in Non-Healing Claw Lesions of Dairy Cattle Reviewed International coauthorship

    Hori K., Taniguchi T., Elpita T., Khemgaew R., Sasaki S., Gotoh Y., Yasutomi I., Misawa N.

    Animals   12 ( 24 )   2022.12

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Animals  

    Non-healing claw lesions (NHCLs) are a newly characterized disorder affecting the deep dermis of the hoof in dairy cattle. Although NHCLs are thought to be associated with bovine digital dermatitis (BDD), their precise etiology is not yet understood. To investigate the bacterial populations present in each type of NHCL (toe necrosis: TN, non-healing white line disease: nhWLD, and a non-healing sole ulcer: nhSU), and the newly added entity non-healing verrucous-like lesions (nhVLL), 16S rRNA-based metagenomic analysis with next-generation sequencing (NGS) was employed. Twelve cases of NHCLs (3 TN, 3 nhWLD, 4 nhSU, and 2 nhVLL) were collected from five dairy farms in two prefectures in Japan. Three samples of healthy hoof dermis collected from two farms and a slaughterhouse were used as controls. Furthermore, culture-dependent and -independent approaches were conducted for detecting Treponema species and Fusobacterium necrophorum. As reported in BDD, Treponema species and F. necrophorum were detected frequently from NHCLs by PCR and immunohistochemistry, but NGS showed that these bacterial genera were not predominant in NHCLs. The predominant bacterial genera in NHCLs differed among the lesions examined, suggesting that Treponema species present predominantly in BDD were not predominant in NHCLs and that the bacterial population in NHCLs may vary among individual cattle and/or farms.

    DOI: 10.3390/ani12243584

    Scopus

  • Survival capability of Campylobacter upsaliensis under environmental stresses Reviewed International coauthorship

    Elmonir, W., Vetchapitak, T., Amano, T., Taniguchi, T., Misawa, N.

    BMC Research Notes   2022.2

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s13104-022-05919-2

    Scopus

  • Porous ceramics adsorbents based on glass fiber-reinforced plastics for NOx and SOx removal Reviewed

    Kinoshita, H., Yasui, K., Hamasuna, T., Yuji, T., Misawa, N., Haraguchi, T., Sasaki, K., Mungkung, N.

    Polymer   14 ( 1 )   2022.1

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Polymers  

    To reuse waste glass fiber-reinforced plastics (GFRPs), porous ceramics (i.e., GFRP/clay ceramics) were produced by mixing crushed GFRP with clay followed by firing the resulting mix-ture under different conditions. The possibility of using ceramics fired under a reducing atmosphere as adsorbent materials to remove NOx and SOx from combustion gases of fossil fuels was investi-gated because of the high porosity, specific surface area, and contents of glass fibers and plastic carbides of the ceramics. NO2 and SO2 adsorption tests were conducted on several types of GFRP/clay ceramic samples, and the gas concentration reduction rates were compared to those of a clay ceramic and a volcanic pumice with high NO2 adsorption. In addition, to clarify the primary factor affecting gas adsorption, adsorption tests were conducted on the glass fibers in the GFRP and GFRP carbides. The reductively fired GFRP/clay ceramics exhibited high adsorption performance for both NO2 and SO2. The primary factor affecting the NO2 adsorption of the ceramics was the plastic carbide content in the clay structure, while that affecting the SO2 adsorption of the ceramics was the glass fiber content.

    DOI: 10.3390/polym14010164

    Scopus

    PubMed

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Books 【 display / non-display

  • 動物の感染症 第4版

    三澤尚明( Role: Contributor)

    近代出版社  2019.3 

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    Language:Japanese Book type:Scholarly book

  • 獣医公衆衛生学Ⅱ 初版第4刷

    三澤尚明 他( Role: Joint editor)

    文永堂出版  2017.3 

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    Language:Japanese Book type:Textbook, survey, introduction

  • 獣医公衆衛生学Ⅰ 初版第4刷

    三澤尚明 他( Role: Joint editor)

    文永堂出版  2017.3 

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    Language:Japanese Book type:Textbook, survey, introduction

  • 大・中・小動物実験プロトコール

    村上昇 他( Role: Joint author ,  マウスを用いたヒトのHelicobacter cinaedi感染モデルの作出と臨床への応用)

    宮崎南印刷  2016.3 

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    Language:Japanese Book type:Scholarly book

  • 獣医公衆衛生学Ⅱ

    三澤尚明他( Role: Joint editor)

    文永堂出版  2014.4 

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    Language:Japanese Book type:Textbook, survey, introduction

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MISC 【 display / non-display

  • 宮崎大学における全学的な設備共同利用体制の構築~学内既存システムとリンクした設備共通管理システムの開発~ Invited

    境健太郎、今井正人、出水信雄、神力はるな、國武久登、三澤尚明、水光正仁

    研究 技術 計画   35 ( 1 )   1 - 9   2020.9

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • ポリマイクロバイアル感染症としての牛趾皮膚炎の病態解明 Invited Reviewed

    三澤尚明、谷口喬子、大岡唯祐、後藤恭宏、林 哲也

    家畜感染症学会誌   9 ( 4 )   139 - 145   2020.9

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • カンピロバクター食中毒のリスク低減対策 Invited

    三澤尚明

    アグリバイオ   2020.5

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  • カンピロバクター食中毒のリスク低減に立ちはだかる課題 Invited

    三澤尚明

    食の安全と安心通信   ( 32 )   2019.1

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)   Publisher:NPO法人食の安全と安心を科学する会  

  • 鶏肉におけるカンピロバクターのリスク低減のための衛生管理対策と課題 Invited

    三澤尚明

    日本食品微生物学雑誌   35 ( 4 )   173 - 178   2018.12

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:日本食品微生物学会  

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Presentations 【 display / non-display

  • 火山灰土壌を用いた水質浄化技術開発に向けた研究 Invited

    谷口喬子、真部航樹、佐々木賢美、三澤尚明

    第40回日本獣医師会獣医学術学会年次大会・日本獣医公衆衛生学会  2022.11.11 

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    Event date: 2022.11.11 - 2022.11.13

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

  • New technologies to control foodborne pathogens Invited International coauthorship International conference

    Misawa, N., Vetchapitak, T., Luangtongkum, T.

    The 21st Federation of Asian Veterinary Association (FAVA) Congress  2022.11.12 

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    Event date: 2022.11.10 - 2022.11.13

    Language:English   Presentation type:Symposium, workshop panel (nominated)  

  • 産業動物防疫コンソーシアムの未来予想図 Invited

    三澤尚明

    令和3年度8大学防疫コンソーシアムシンポジウム  2022.1.25 

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    Event date: 2022.1.25

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

  • Food safety from farm to table Invited International conference

    三澤尚明

    JICAベトナム青年研修事業  2022.1.14 

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    Event date: 2022.1.14 - 2022.1.21

    Language:English   Presentation type:Oral presentation (general)  

  • Campylobacter jejuniはコレラ様エンテロトキシンを産生するのか

    三澤尚明

    第53回九州微生物研究会  2021.12.10 

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    Event date: 2021.12.10

    Language:Japanese   Presentation type:Oral presentation (general)  

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Works 【 display / non-display

  • バイオリソースデータベースの構築

    2015.4

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    産業動物防疫リサーチセンターが提供するバイオリソースとして、野生動物(シカ、イノシシ)の血清を収集し、共同利用に供するためのデータベースを構築した。

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Awards 【 display / non-display

  • 日本獣医師会獣医学術賞・獣医学術学会賞(公衆衛生部門)

    2022.11   日本獣医師会   火山灰土壌を用いた水質浄化技術開発に向けた研究

    谷口喬子、真部航樹、佐々木賢美、三澤尚明

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    Award type:Award from Japanese society, conference, symposium, etc. 

  • 第13回日本カンピロバクター研究会総会優秀発表賞

    2020.10   日本カンピロバクター研究会   Efficacy of a high-pressure pulse jet spray technology and chemical treatment for decontamination of Campylobacter jejuni and spoilage bacteria on chicken skin

    Torrung Vetchapitak, Satomi Sasaki, Takako Taniguchi, Taradon Luangtongkum and Naoaki Misawa

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 宮崎県獣医師会功労者表彰

    2020.6   宮崎県獣医師会  

    三澤尚明

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    Country:Japan

  • Best 3-min pitch award

    2019.6   The 19th International Symposium of the World Association of Veterinary Laboratory Diagnosticians   Development of an effective decontamination of Campylobacter species on chicken carcasses.

    Vetchapitak, T., Shinki, T., Sasaki, S., Taniguchi, T., Misawa, N.

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    Award type:Award from international society, conference, symposium, etc.  Country:Thailand

  • 日本食品微生物学会優秀賞

    2018.9   日本食品微生物学会   ブロイラー皮膚とカンピロバクター外膜の結合に関与する蛋白の同定

    谷口喬子、大木万由子、三澤尚明

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

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Grant-in-Aid for Scientific Research 【 display / non-display

  • ウエルシュ菌食中毒の制御のための検査法の開発及び汚染実態把握のための研究

    Grant number:XA12210101  2022.04 - 2025.03

    厚生労働省  厚生科研  食品の安全確保推進研究事業

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    Authorship:Coinvestigator(s) 

  • 牛趾乳頭腫症病変内のトレポネーマの病原性をサポートする細菌群の探索と機能解明

    Grant number:21K05923  2021.04 - 2024.03

    独立行政法人日本学術振興会  科学研究費助成事業  基盤研究(C)

    谷口喬子

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    Authorship:Coinvestigator(s) 

  • カンピロバクターの鶏皮膚に対する付着因子の探索とその生物学的意義の解明

    Grant number:21K05921  2021.04 - 2024.03

    独立行政法人日本学術振興会  科学研究費助成事業  基盤研究(C)

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    Authorship:Principal investigator 

  • 人獣由来helicobacter cinaedi感染・発症におけるT6SSの役割

    2017.04 - 2020.03

    科学研究費補助金  基盤研究(C)

    谷口喬子、三澤尚明

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    Authorship:Coinvestigator(s) 

  • 動物及び食品由来カンピロバクター株におけるギランバレー症候群発症リスク因子の分析

    2016.04 - 2019.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

    カンピロバクター感染症の合併症であるギランバレー症候群を引き起こす細菌側のリスク因子を家畜や食品由来株から探索する。

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Other external funds procured 【 display / non-display

  • The Acceleration of Livestock Revolution in Thailand aiming to be the Kitchen of the World through the Development of Novel Technologies for Stable Livestock Production and Food Safety International coauthorship

    2022.04 - 2024.10

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    Authorship:Principal investigator 

  • Acquisition of stress-tolerance in Campylobacter jejuni in foods and its control of transmission

    2019.04 - 2019.05

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    Authorship:Principal investigator  Grant type:Competitive

  • Enhancement of the livestock productivity and reinforcement of countermeasure f

    2017.04 - 2020.03

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    Authorship:Principal investigator  Grant type:Competitive

Other research activities 【 display / non-display

  • バイオリソースデータベースの構築

    2015.04

     More details

    産業動物防疫リサーチセンターが提供するバイオリソースとして、野生動物(シカ、イノシシ)の血清を収集し、共同利用に供するためのデータベースを構築した。

Available Technology 【 display / non-display

  • 食肉の微生物制御に関する研究
    新規殺菌剤の製造と応用に関する研究
    微生物吸着・殺菌作用を有する土壌素材を用いた微生物制御技術の開発研究

     詳細を見る

    Related fields where technical consultation is available:カンピロバクター食中毒、食中毒制御、食肉衛生、細菌・ウイルスの殺菌・不活化、新型コロナウイルス不活化試験、バイオテロ対策、畜産等の環境の浄化技術、各種受託検査(牛乳房炎、牛白血病、水質検査、カンピロバクター等)

    Message:・食鳥処理場における鶏肉のカンピロバクター制御技術について関心をお持ちの方はご連絡ください。・コストをかけず畜舎環境などの浄化を行いたいとお考えの方はご相談ください。・牛乳房炎や牛白血病(牛伝染性リンパ腫)等の検査・診断等を希望される方はご相談ください。