UEMURA Ryoko

写真a

Affiliation

Faculty of Agriculture Department of Veterinary Science

Title

Associate Professor

External Link

Degree 【 display / non-display

  • 博士(獣医学) ( 2004.3   山口大学 )

Research Areas 【 display / non-display

  • Life Science / Veterinary medical science

 

Papers 【 display / non-display

  • Efficacy of Treating Bacterial Bioaerosols with Weakly Acidic Hypochlorous Water: A Simulation Chamber Study Reviewed

    Norkaew S, Narikawa S, Nagashima U, Uemura R, Noda J

    Heliyon   2024.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: https://doi.org/10.2139/ssrn.4571988

  • The presence of adhesion factors NOX, α-enolase, TrmFO, P27, and VpmaX in Mycoplasma bovis wild isolates in Japan Reviewed

    Shitamori F., Uemura R., Kanda T., Sueyoshi M.

    Open Veterinary Journal   12 ( 6 )   782 - 786   2022.11

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Open Veterinary Journal  

    Background: Mycoplasma bovis causes various diseases such as bronchopneumonia, otitis media, arthritis, and mastitis in cattle. Mycoplasma bovis is often isolated from the deep pharynges of healthy cattle and is generally considered not to cause clinical symptoms while in the upper respiratory tract. In mycoplasma infections, adhesion to the host cells is a crucial step. In recent years, five new adhesins, NOX, α-enolase, TrmFO, P27, and VpmaX, have been reported in M. bovis strains from pneumonia cases. However, the presence of these adhesins in wild isolates has not been established. Aim: This study aimed to investigate the presence of these adhesin genes in wild isolates isolated from cattle nasal cavities and lesion sites (pneumonia, otitis media, arthritis, and mastitis) in various regions in Japan and clarify the relationship between adhesion and the symptoms caused by M. bovis infection. Methods: A total of 141 M. bovis wild isolates isolated from nasal cavities (healthy or sick cattle), lungs with pneumonia, ears with otitis media, joint fluids of arthritic animals, and milk of mastitic animals. Mycoplasma bovis type strain PG45 was also used. Specific polymerase chain reaction reactions were performed to detect nox, α-enolase, trmFO, P27, and vpmaX, which are adhesins of M. bovis. Results: This study reports 139 M. bovis wild isolates were positive for nox, α-enolase, trmFO, P27, and vpmaX, while two isolates each lacked α-enolase or P27 genes. Mycoplasma bovis PG45 also had all five adherens genes. Conclusion: Almost all M. bovis wild isolates possessed all nox, α-enolase, trmFO, P27, and vpmaX genes regardless of the lesion site or region of origin. This means no relationship was found between the presence of the five adhesins and lesion sites in M. bovis and M. bovis isolated from the nasal cavities of asymptomatic cattle have the same numbers and types of adhesins as isolates from symptomatic lesion sites (pneumonia, otitis media, arthritis, and mastitis). This suggests that not only M. bovis isolates from pulmonary lesions, but also M. bovis existing in the nasal cavity has the potential to causes symptoms in the host.

    DOI: 10.5455/OVJ.2022.v12.i6.1

    Scopus

  • Effects of Probiotics on Growth and Immunity of Piglets. Reviewed

    Azizi AFN, Uemura R, Omori M, Sueyoshi M, Yasuda M

    Animals : an open access journal from MDPI   12 ( 14 )   2022.7

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3390/ani12141786

    PubMed

  • Natural Mycoplasma bovis infection associated with epithelioid granulomatous caseonecrotic bronchiolitis at a progressed disease stage in calves Reviewed

    Mathurot Suwanruengsri Ryoko Uemura Uda Zahli Izzati Takuya Kanda Naoyuki Fuke Masahiro Yasuda Takuya Hirai Ryoji Yamaguchi

    Thai J Vet Med.   52 ( 1 )   33 - 44   2022.1

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Journal of Comparative Pathology  

    Mycoplasma hyopneumoniae (Mhp) is the primary pathogen of porcine enzootic pneumonia (PEP). Consolidated lung tissue from the cranioventral lung lobes of 15 pigs with PEP was collected for quantitative polymerase chain reaction, histopathology and immunohistochemistry. Histopathology revealed the co-existence of bronchial-associated lymphoid tissue hyperplasia with intra-alveolar neutrophils and macrophage infiltration in lesions of suppurative bronchopneumonia. Immunolabelling of infiltrated macrophages with CD163/CD204 indicated the presence of M2-polarized macrophages. Mhp antigen was detected on respiratory epithelial cells and in phagocytosed neutrophils. The intensity of Mhp immunolabelling and number of CD163/CD204-positive macrophages were correlated with the Mhp load in lung tissue (r = 0.87, 0.56, P <0.05). IL-8 immunolabelling was mainly found in neutrophils and correlated with Mhp load, Mhp immunolabelling and histological lesion score (r = 0.70, 0.66, 0.64, P <0.05), respectively. Apoptosis was seen in intra-alveolar cells and was correlated with Mhp load (r = 0.62, P <0.05). It is postulated that IL-8 attracts neutrophils to the lesions, while M2-polarized macrophages are a major source of IL-10 and promote a Th2-type immune response.

    DOI: 10.14456/tjvm.2022.4

    Scopus

  • Optimizing antimicrobial use by improving medication adherence among pig producers Reviewed

    Toya, Ryohei; Sasaki, Yosuke; Uemura, Ryoko; Sueyoshi, Masuo

    Animal Science Journal   2022

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books 【 display / non-display

  • 動物の衛生 第2版

     ( Role: Contributor)

    文永堂出版  2020.3 

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    Language:Japanese Book type:Textbook, survey, introduction

  • 獣医微生物学第4版

    関崎勉、遠矢幸伸、福士秀人、堀本泰介、村瀬敏之 編集( Role: Contributor)

    文永堂出版  2018.7 

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    Total pages:514   Responsible for pages:204-210   Language:Japanese Book type:Textbook, survey, introduction

  • 大・中・小動物実験プロトコール

    上村涼子( Role: Joint author ,  動物実験の対象と関連する法令, 牛や豚などの産業動物を対象とした研究)

    宮日文化情報センター  2016.3 

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    Language:Japanese Book type:Textbook, survey, introduction

MISC 【 display / non-display

  • ロープワークをマスターしよう⑦ 尾の保定その1 尾房の結び方 Invited

    上村涼子

    DAIRYMAN   68 ( 8 )   59 - 59   2018.8

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:デーリィマン社  

  • 鼻汁などから容易に感染、マイコプラズマ性肺炎に注意 Invited

    上村涼子

    DAIRYMAN   68 ( 8 )   42 - 43   2018.8

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:デーリィマン社  

  • ロープワークをマスターしよう⑥ 柵への係留その2 もやい結びと馬結び Invited

    上村涼子

    DAIRYMAN   68 ( 7 )   65 - 65   2018.7

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:デーリィマン社  

  • ロープワークをマスターしよう⑤ 柵への係留その1 基本の3パターン Invited

    上村涼子

    DAIRYMAN   68 ( 6 )   57 - 57   2018.6

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:デーリィマン社  

  • ロープワークをマスターしよう④ 頭絡編その2 鼻周りのサイズを固定する結び方 Invited

    上村涼子

    DAIRYMAN   68 ( 5 )   61 - 61   2018.5

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:デーリィマン社  

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Presentations 【 display / non-display

  • The effect of Hypochlorous acid water on biofilm bacteria

    Lin Cherry San・上村凉子・末吉益雄

    令和3年度日本家畜衛生学会  2021.12.3 

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    Event date: 2021.12.3

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 2001~2017年に国内のサラブレッド競走馬の肺炎症例から分離された 腸管外病原性大腸菌に関する研究

    〇鳥越克馬1)・上村涼子1)・井口 純2)・丹羽秀和3)・末吉益雄1)

    令和3年度日本家畜衛生学会  2021.12.3 

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    Event date: 2021.12.3

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Mycoplasma bovisが牛好中球の遊走性と貪食に与える影響

    ○下森文敬1)、上村涼子1)、小林郁雄2)、末吉益雄1)

    令和3年度獣医学術九州地区学会  2021.11.22 

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    Event date: 2021.11.22

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 頭部腫脹牛の予後診断における生検の有用性について

    ○佐藤礼一郎1)、北原豪2)、上村涼子3) 平井卓哉4)、山口良二4)、相原尚之5)、 山田一孝6)

    令和3年度獣医学術九州地区学会  2021.11.22 

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    Event date: 2021.11.22

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 加療により良好な経過を辿った咽頭膿瘍の黒毛和種育成牛

    ○一門亮佑1)、石田翔悟1)、KIM SUEUN2)、上村涼子3)、中間由規4)、佐藤礼一郎1)

    令和3年度獣医学術九州地区学会  2021.11.22 

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    Event date: 2021.11.22

    Language:Japanese   Presentation type:Oral presentation (general)  

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Awards 【 display / non-display

  • 第163回獣医学会微生物分科会若手奨励賞

    2020.9   日本獣医学会微生物分科会   牛好中球へのMycoplasma bovis感作の影響

    上村悠祐, 上村涼子, 小林郁雄, 末吉益雄.

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 第162回獣医学会微生物分科会若手奨励賞

    2019.9   日本獣医学会微生物分科会   Mycoplasma bovis感作に対する牛肺胞マクロファージのサイトカイン発現応答

    甲斐慎二, 上村涼子, 石川真悟, 帆保誠二, 小林郁雄, 保田昌宏, 末吉益雄.

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 平成29年日本家畜臨床学会長賞

    2017.11   日本家畜臨床学会  

    國保健浩、上村涼子 ほか

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    Award type:Honored in official journal of a scientific society, scientific journal  Country:Japan

  • The 7th International Symposium on Emerging and Re-emerging Pig Diseases 2015 Student Award

    2015.6   The 7th International Symposium on Emerging and Re-emerging Pig Diseases  

    中村有紀子、上村涼子 ほか

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    Award type:Award from international society, conference, symposium, etc.  Country:Japan

  • The 7th International Symposium on Emerging and Re-emerging Pig Diseases 2015 Student Award

    2015.6   The 7th International Symposium on Emerging and Re-emerging Pig Diseases  

    大森麻里子、上村涼子 ほか

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    Award type:Award from international society, conference, symposium, etc.  Country:Japan

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Grant-in-Aid for Scientific Research 【 display / non-display

  • 牛マイコプラズマ肺炎の病態診断に関する研究

    2015.04 - 2018.03

    科学研究費補助金  若手研究(B)

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    Authorship:Principal investigator 

    牛マイコプラズマ肺炎は、主にMycoplasma bovisを原因菌とする感染症で、発症すると不可逆的な乾酪壊死性肺炎の経過をたどって廃用淘汰されるなど経済的損失が大きく、近年特に問題となっている。本病の最も大きな問題点は、①健常牛からもM. bovisが分離され発症が日和見的であること、②病態把握が難しく結果的に長期加療の上で廃用となるため、治療費、飼料代、労力などの経済的損失が大きいこと、③さらにその発症牛が農場内の感染源となり続けることがあげられる。この課題解決のために、1)牛マイコプラズマ肺炎の病態進行メカニズムの解明、2)M. bovis浸潤農場での易感染個体把握システムおよび発症個体の病態診断システムの開発を行い、最終的に、M. bovis浸潤農場における牛マイコプラズマ肺炎による損耗低減化のための飼養管理技術の開発を目指す。