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医学部 附属病院 消化管・内分泌・小児外科 |
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助教 |
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論文 【 表示 ／ 非表示 】
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Spatiotemporal expression of HMGB2 regulates cell proliferation and hepatocyte size during liver regeneration. 査読あり
Yano K, Choijookhuu N, Ikenoue M, Fukaya T, Sato K, Lee D, Taniguchi N, CHosa Em Nanashima A, Hisikawa Y
Scientific Reports 2022年7月
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Knowledge survey regarding blast wound education of student doctors at a local academic medical university in Japan.
Kwano F, Munakata S, Tashiro K, Ikenoue M, Furukawa K, Ochiai H, Nakamura K, Nanashima A
Turkish Journal of Surgery 2022年5月
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Depletion of high-mobility group box 2 causes seminiferous tubule atrophy via aberrant expression of androgen and estrogen receptors in mouse testis†.
Sugita N, Choijookhuu N, Yano K, Lee D, Ikenoue M, Fidya, Taniguchi N, Chosa E, Hishikawa Y
Biology of reproduction 2021年10月
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Kawano F., Tashiro K., Ikenoue M., Munakata S., Nakao H., Mizuno T., Mori H., Ikeda T., Takeno S., Furukawa K., Tomita M., Endo G., Ochiai H., Nakamura K., Nanashima A.
Surgery Today 51 ( 6 ) 1001 - 1009 2021年6月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Surgery Today
Purposes: Balancing scheduled surgery and trauma surgery is difficult with a limited number of surgeons. To address the issues and systematize education, we analyzed the current situation and the effectiveness of having a trauma team in the ER of a regional hospital. Methods: This retrospective study analyzed the demographics, traumatic variables, procedures, postoperative morbidities, and outcomes of 110 patients who underwent trauma surgery between 2012 and 2019. The trauma team was established in 2016 and our university hospital Emergency Room (ER) opened in 2012. Results: Blunt trauma accounted for 82% of the trauma injuries and 39% of trauma victims were transported from local centers to our institute. The most frequently injured organs were in the digestive tract and about half of the interventions were for hemostatic surgery alone. Concomitant treatments for multiple organ injuries were performed in 31% of the patients. The rates of postoperative severe complications (over Clavien–Dindo IIIb) and mortality were 10% and 13%, respectively. Fourteen (12.7%) of 24 patients who underwent damage-control surgery died, with multiple organ injury being the predominant cause of death. Conclusion: Systematic education or training of medical students and general surgeons, as well as the co-operation of the team at the regional academic institute, are necessary to overcome the limited human resources and save trauma patients.
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Takeno S., Tanoue Y., Hamada R., Kawano F., Tashiro K., Wada T., Ikenoue M., Nanashima A., Nakamura K.
Surgical Endoscopy 34 ( 8 ) 3479 - 3486 2020年8月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Surgical Endoscopy
© 2019, Springer Science+Business Media, LLC, part of Springer Nature. Background: This study aimed to assess the surgical difficulty of minimally invasive esophagectomy in the left lateral decubitus position for patients with esophageal cancer from the perspective of short-term outcomes, including operation time, blood loss, and morbidity. Materials and methods: The initial 44 consecutive patients with esophageal cancer who underwent minimally invasive esophagectomy were statistically analyzed retrospectively. Thoracic cage area was measured from preoperative computed tomography as a factor affecting the surgical difficulty of minimally invasive esophagectomy, as well as other patient characteristics. Correlations with short-term outcomes including chest operation time, blood loss, and morbidity rate were then examined. Results: In univariate analyses, smaller area of the upper thoracic cage width correlated with prolonged thoracic procedure time (p = 0.0119) and greater blood loss during thoracic procedures (p = 0.0283), but area of the lower thoracic cage showed no correlations. History of respiratory disease was associated with thoracic procedure time (p < 0.0001), but not blood loss. In multivariate analysis, small area of the upper thoracic cage was independently associated with prolonged thoracic procedure time (p = 0.0253). Small upper thoracic cage area was not directly correlated with morbidity rate, but prolonged thoracic procedure time was associated with increased blood loss (p < 0.0001) and morbidity rate (p = 0.0204). Empirical time reduction (p = 0.0065), but not blood loss, was associated with thoracic procedure time. However, area of the upper thoracic cage did not correlate with empirical case number. In multivariate analysis, area of the upper thoracic cage (p = 0.0317) and empirical case number (p = 0.0193) correlated independently with thoracic procedure time. Conclusion: A small area of the upper thoracic cage correlated significantly with prolonged thoracic procedure time and increased thoracic blood loss for minimally invasive esophagectomy in the left lateral decubitus position, suggesting the surgical difficulty of minimally invasive esophagectomy in the left lateral decubitus position.
科研費（文科省・学振・厚労省）獲得実績 【 表示 ／ 非表示 】
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脂肪肝マウスの肝再生過程でのミトコンドリア脂質代謝へのエストロゲンの関与
研究課題/領域番号：21K06738 2021年04月 - 2024年03月
独立行政法人日本学術振興会 科学研究費補助金 基盤研究(C)
菱川 善隆,
担当区分：研究分担者