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Affiliation |
Faculty of Medicine College Hospital Psychiatry department |
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Title |
Assistant Professor |
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External Link |
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HARUTA Ayaka
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Campus Career 【 display / non-display 】
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University of Miyazaki Faculty of Medicine College Hospital Psychiatry department Assistant Professor
2026.04 - Now
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University of Miyazaki Faculty of Medicine School of Medicine Department of Clinical Neuroscience, Psychiatry Assistant Professor
2015.04 - 2023.03
Papers 【 display / non-display 】
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Perampanel attenuates scratching behavior induced by acute or chronic pruritus in mice Reviewed
Haruta-Tsukamoto A., Miyahara Y., Funahashi H., Nishimori T., Ishida Y.
Biochemical and Biophysical Research Communications 533 ( 4 ) 1102 - 1108 2020.12
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) Publisher：Biochemical and Biophysical Research Communications
An itch is defined as an unpleasant sensation that evokes a desire to scratch. Glutamate is a major excitatory neurotransmitter in the mammalian central nervous system and has a crucial role in pruriceptive processing in the spinal dorsal horn. It is well known that glutamate exerts its effects by binding to various glutamate receptors including α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, and that AMPA/kainate receptors play a crucial role in pruriceptive processing; however, the precise role of AMPA receptors remains uncertain. Perampanel, an antiepileptic drug, is an antagonist of AMPA receptors. Pretreatment with perampanel dose-dependently attenuated the induction of scratching, a behavior typically associated with pruritus, by intradermal administration of the pruritogen chloroquine. In addition, the induction of scratching in mice painted with diphenylcyclopropenone and NC/Nga mice treated with Biostir AD, animal models of contact dermatitis and atopic dermatitis, respectively, was dose-dependently alleviated by administration of perampanel. These findings indicate that AMPA receptors play a crucial role in pruriceptive processing in mice with acute or chronic pruritus.
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Alleviation of thalamic pain by cilostazol administration: a case report Reviewed
Haruta-Tsukamoto A, Funahashi H, Miyahara Y, Matsuo T, Nishimori T, Ishida Y
Clinical case reports 2018.2
Language：English Publishing type：Research paper (scientific journal)
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Evaluation of the effects of a team-based systematic prevention and management program for postoperative orthopedic older patients: A retrospective cohort study. Reviewed
Yamaguchi F, Inomata C, Yoshinaga N, Sawada H, Shimamoto K, Haruta‐Tsukamoto A
Psychiatry and Clinical Neurosciences Reports 3 ( 4 ) e70021 2024.9
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1002/pcn5.70021
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宮崎大学医学部附属病院精神科におけるコンサルテーション リエゾン精神医療の現状（第２報） Reviewed
塚本彩香，直野慶子，武田龍一郎，船橋英樹，宇田川充隆，三好良英，松尾寿栄，安部博史，石田康
宮崎県医師会医学雑誌 ( 1 ) 2015.4
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)
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Role of kainate receptors in pruriceptive processing in the mouse spinal cord. Reviewed
Haruta-Tsukamoto A, Kanemaru-Kawazoe A, Kogoh Y, Miyahara Y, Funahashi H, Hirano Y, Nishimori T, Ishida Y
European journal of pharmacology 957 175998 2023.10
Authorship：Lead author, Corresponding author Language：English Publishing type：Research paper (scientific journal)
Presentations 【 display / non-display 】
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Kainate receptors contribute to acute itch processing in mice
2021.7.14
Event date： 2021.7.14 - 2021.7.16
Language：English Presentation type：Oral presentation (general)
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Effect of perampanel on chronic itch behavior induced by diphenylcyclopropenone in mice
2020.8.23
Event date： 2020.8.21 - 2020.8.23
Language：English Presentation type：Poster presentation
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宮崎大学医学部附属病院における精神科リエゾンチームの活動報告（第２報）
治田彩香
第72回九州精神神経学会・第65回九州精神医療学会 2019.12.13
Event date： 2019.12.12 - 2019.12.13
Language：Japanese Presentation type：Oral presentation (general)
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Effect of perampanel on acute itch behavior induced by chloroquine, serotonin or histamine in mice International conference
治田彩香
Neuroscience 2019, Society for Neuroscience 2019.9
Event date： 2019.9.19 - 2019.9.23
Language：English Presentation type：Poster presentation
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宮崎大学医学部附属病院における精神科リエゾンチームの活動報告
治田彩香
第71回九州精神神経学会 2019.2.1
Event date： 2019.1.31 - 2019.2.1
Language：Japanese Presentation type：Oral presentation (general)
Grant-in-Aid for Scientific Research 【 display / non-display 】
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難治性痒みの伝達機構におけるグルタミン酸受容体の役割の解明
Grant number：23K14301 2023.04 - 2026.03
独立行政法人日本学術振興会 科学研究費基金 若手研究
Authorship：Principal investigator