|
所属 |
医学部 医学科 社会医学講座公衆衛生学分野 |
|
職名 |
講師 |
|
外部リンク |
|
論文 【 表示 ／ 非表示 】
-
Socio-Demographic, Health, and Transport-Related Factors Affecting the COVID-19 Outbreak in Myanmar: A Cross-Sectional Study 査読あり
Aung K., Kuroda Y., Hinoura T.
Cureus 14 ( 9 ) 2022年9月
担当区分：責任著者 掲載種別：研究論文（学術雑誌）
DOI： 10.7759/cureus.29693
-
PER3 polymorphisms and their association with prostate cancer risk in Japanese men 査読あり
Hinoura T., Mukai S., Kamoto T., Kuroda Y.
Journal of Preventive Medicine and Hygiene 62 ( 2 ) 489 - 495 2021年7月
担当区分：筆頭著者 掲載種別：研究論文（学術雑誌） 出版者・発行元：Journal of Preventive Medicine and Hygiene
Introduction. Prostate cancer (PCa) is one of the most common cancers affecting men globally. Although PER3 has been suggested as a risk factor for cancer development, there are few reports elucidating the relationship between PER3 and PCa. We investigated the association between PER3 polymorphisms (rs2640908 and VNTR) and susceptibility to PCa in the Japanese population. Methods. Eighty three patients with PCa and 122 controls participated in this study. We analyzed rs2640908 and VNTR polymorphisms by using PCR-Restriction Fragment Length Polymorphism (PCR-RFLP). Results. Compared to the C/C genotype with the rs2640908 polymorphism, the T/T (OR: 0.35, 95% CI: 0.15-0.81, P = 0.02) and C/T + T/T (OR: 0.46, 95% CI: 0.24-0.88, P = 0.02) genotypes had a significantly lower risk of PCa. TT (OR: 0.29, 95% CI: 0.10-0.77, P = 0.02) and CT + TT (OR: 0.47, 95% CI: 0.23-0.97, P = 0.04) also had significant protection against PCa in the smoker group. Significantly, we observed an association between smoking and rs2640908 polymorphism in this study. However, no association between the VNTR polymorphisms and PCa was detected. Conclusions. Our results suggest that PER3 rs2640908 polymorphisms influence an individual’s susceptibility to PCa.
-
The Relationship between Lithium Concentration in Drinking Water and Suicide Mortality: A Systematic Review 査読あり
Aung KZ., Hinoura T., Kozaka N., Kuroda Y.
International Journal of Physical Medicine and Rehabilitation 9 ( 2 ) 2021年3月
掲載種別：研究論文（学術雑誌）
-
Holipah, Maharani A., Sujarwoto S., Hinoura T., Kuroda Y.
Vaccines 8 ( 3 ) 2020年9月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Vaccines
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Although 91% of 12–23-month-old children in Indonesia received at least one immunization in 2013, only 76% completed DTP3 immunization. This percentage is below the UNICEF and WHO recommended standards. Thus, this study aims to investigate trends, spatial disparities, and social determinants related to low coverage of DTP3 immunization in Indonesia. Using a multilevel approach, we analyzed data from 305,090 12–23-month-old children living across approximately 500 districts in Indonesia to study demand and supply factors determining DTP3 immunization status. We examined unique, nationally representative data from the National Socioeconomic Survey (Survei Sosial Ekonomi Nasional or Susenas) and Village Potential Census (Potensi Desa or Podes) from 2004 to 2016. The percentage of children receiving complete DTP3 immunization increased from 37.8% in 2004 to 75.9% in 2016. Primarily income, parity status, and education, showed influence on DTP3 coverage. Among individual-level factors, the presence of a professional birth attendant was the most influential factor. At the district level, the factors varied. Low progress in DTP3 immunization status in Indonesia is due to huge disparities across the country’s islands, in the density of health services, and in household socioeconomic status.
-
Holipah, Hinoura T., Kuroda Y.
Gan To Kagaku Ryoho 47 ( 6 ) 941 - 946 2020年6月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Japanese Journal of Cancer and Chemotherapy
© 2020 Japanese Journal of Cancer and Chemotherapy Publishers Inc.. All rights reserved. Colorectal cancer (CRC) accounted for the largest number of new cases of cancer in 2018. CRC is caused by a multifactorial disease process including disruption of the circadian rhythm. Period 1 (PER1), as one of the circadian genes, has a role in the cell cycle as well as influence on the cancer process. In this research, we investigate the association of PERI (rs3027188) polymorphism and susceptibility to CRC in conjunction with gender and smoking status. This research was a case-control study in the Japanese population which included 121 CRC patients and 197 noncancerous clinical controls. Genomic deoxyribonucleic acid (DNA) was extracted from peripheral blood lymphocytes. The analysis to detect single-nudeotide polymorphisms (SNPs) in PER1 (rs3027188) used polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Overall, there was no significant association between PER1 (rs3027188) and CRC. When stratified by gender and smoking status, the results indicated that, compared with the C/C genotype, the G/G genotype among females was significantly less common in the cancer cases than in the controls (adjusted ORs: 0.19 [95%CI: 0.04-0.95]). A significant association was found between the G allele of PER1 (rs3027188) and reduced risk of CRC in females, while smoking had no association with PER1 (rs3027188) in CRC.
講演・口頭発表等 【 表示 ／ 非表示 】
-
宮崎県における重症熱性血小板減少症候群(SFTS)に関する疫学調査
日野浦拓之
第31回九州農村医学会
開催年月日： 2022年8月20日
会議種別：口頭発表（一般）
-
日本人男性における前立腺がんとPER3時計遺伝子多型との関係
日野浦拓之
日本産業衛生学会九州地方会
開催年月日： 2021年10月16日
会議種別：口頭発表（一般）
-
宮崎県におけるSFTS感染に関する疫学調査
日野浦拓之
第91回日本衛生学会学術総会
開催年月日： 2021年3月6日 - 2021年3月8日
記述言語：日本語 会議種別：口頭発表（一般）
-
ミャンマーにおけるコロナ(COVID-19)感染拡大要因に関する研究
KHINE ZIN AUNG
第91回日本衛生学会学術総会
開催年月日： 2021年3月6日 - 2021年3月8日
記述言語：日本語 会議種別：口頭発表（一般）
-
宮崎県におけるSFTS感染に関する抗体測定を含む疫学調査
日野浦拓之
第90回日本衛生学会学術総会
開催年月日： 2020年3月26日 - 2020年3月28日
記述言語：日本語 会議種別：口頭発表（一般）
科研費（文科省・学振・厚労省）獲得実績 【 表示 ／ 非表示 】
-
鉱物油のT細胞に与える影響についての研究
研究課題/領域番号：19H03887 2019年04月 - 2024年03月
独立行政法人日本学術振興会 科学研究費補助金 基盤研究(B)
黒田 嘉紀、
担当区分：研究分担者
-
ミャンマーヒ素汚染地域での発達、発育に関するコホート調査
研究課題/領域番号：18KK0267 2018年10月 - 2023年03月
独立行政法人日本学術振興会 科学研究費補助金 国際共同研究加速基金(国際共同研究強化(B))
黒田 嘉紀、
担当区分：研究分担者