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Affiliation |
Faculty of Medicine College Hospital Urology |
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Assistant Professor |
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External Link |
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Related SDGs |
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AKIOKA Takahiro
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Papers 【 display / non-display 】
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Abe J., Murashima T., Kojima S., Ueno T., Takei A., Nakai N., Akioka T., Kamoto T., Sawada A.
International Journal of Clinical Oncology 2026.2
Publishing type：Research paper (scientific journal) Publisher：International Journal of Clinical Oncology
Advances in immuno-oncology (IO)-based systemic therapies have improved treatment outcomes for patients with metastatic renal cell carcinoma (mRCC). However, long-term survival of these patients remains challenging, highlighting the need to reassess the role of local and metastasis-directed treatments. Cytoreductive nephrectomy (CN) has traditionally been a part of the therapeutic armamentarium for mRCC, and evidence from the targeted therapy era—most notably the CARMENA and SURTIME trials—indicates that deferred CN after initial systemic therapy may benefit carefully selected patients. In the IO era, prospective evidence regarding CN is lacking, although ongoing trials, such as NORDIC-SUN and PROBE, are expected to refine patient selection and optimal timing. Real-world analysis reveals a significant decline in conducting CN since 2018. However, CN remains associated with improved overall survival of patients who received several IO-based first-line regimens after adjustment for baseline characteristics. Metastasis-directed treatments, including metastasectomy and local interventions for bone metastases, continue to exhibit potential survival benefits and may maintain functional status when complete resection of lesions is achievable. Considering the absence of definitive prospective data applicable to routine clinical practice, individualized treatment strategies should consider CN and local therapies alongside systemic treatment response, tumor biology, and patient-specific prognostic factors.
Presentations 【 display / non-display 】
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後腹膜到達法に経腹的到達法を併用した右腎摘除術の経験
秋岡貴弘, 寺田直樹, 植野尭, 中原梢, 山崎浩司, 藤井将人, 永井崇敬, 髙森大樹, 木田和貴, 上村敏雄, 向井尚一郎, 賀本敏行
第32回日本泌尿器内視鏡学会総会
Event date： 2018.11.27 - 2018.11.29
Language：Japanese Presentation type：Oral presentation (general)
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腹腔鏡下に切除しえた膀胱頸部パラガングリオーマの1例
秋岡貴弘, 藤井将人, 月野浩昌, 上村敏雄, 向井尚一郎, 賀本敏行
日本泌尿器科学会第195回熊本地方会
Event date： 2018.3.10
Language：Japanese Presentation type：Oral presentation (general)
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組織診断に苦慮した腎オンコサイトーマの一例
秋岡貴弘
第7回泌尿器病理研究会学術集会
Event date： 2018.2.10
Language：Japanese Presentation type：Oral presentation (general)
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左腎尿路結石に対するECIRSで多量の膿瘍が判明した一例
秋岡貴弘, 下村貴宏, 岩本秀安, 佐藤俊介
第88回日本泌尿器科学会宮崎地方会
Event date： 2017.1.21
Language：Japanese Presentation type：Oral presentation (general)
Grant-in-Aid for Scientific Research 【 display / non-display 】
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転移性CRPCにおける、HGF/METパスウェイを標的とした新規治療法の開発
Grant number：23K08737 2023.04 - 2026.03
独立行政法人日本学術振興会 科学研究費補助金 基盤研究（C）
Authorship：Coinvestigator(s)
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ヒト化マウスを用いた腎細胞癌PDXモデルの樹立とMET阻害薬効果予測因子の同定
Grant number：22K09506 2022.04 - 2025.03
独立行政法人日本学術振興会 科学研究費補助金 基盤研究（C）
Authorship：Coinvestigator(s)