MIYAUSHIRO Sae

写真a

Affiliation

Faculty of Medicine College Hospital Cancer diagnosis and treatment part

Title

Assistant Professor

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  • Nasopharyngeal carcinoma with bone marrow metastasis: Positive response to weekly paclitaxel chemotherapy

    Miyaushiro S., Kitanaka A., Kubuki Y., Hidaka T., Shide K., Kameda T., Sekine M., Kamiunten A., Umekita Y., Kawabata T., Ishiguro Y., Shimoda K.

    Internal Medicine   54 ( 11 )   1455 - 1459   2015.6

     More details

    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Internal Medicine  

    © 2015 The Japanese Society of Internal Medicine. A 51-year-old man with nasopharyngeal carcinoma underwent chemoradiotherapy with cisplatin and 5fluorouracil, followed by a left cervical lymphadenectomy. Distant metastatic disease was excluded using fluoro-deoxyglucose positron emission tomography. Seven months later, bone marrow metastasis and disseminated intravascular coagulation were diagnosed. The patient received weekly paclitaxel therapy and maintained a good performance status for seven months. During the treatment period, the patient developed no severe organ toxicity except for neutropenia. Weekly paclitaxel may therefore be considered as the treatment of choice in patients with advanced or recurrent nasopharyngeal carcinoma with bone marrow metastasis.

    DOI: 10.2169/internalmedicine.54.3917

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    PubMed