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Faculty of Medicine School of Medicine Department of Medicine of Sensory and Motor Organs, Orthopedic Surgery |
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Assistant Professor |
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Related SDGs |
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YOKOE Takuji
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Papers 【 display / non-display 】
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Approximately two-thirds of adolescent male soccer players had increased lateral ankle laxity with functional ankle impairments. Reviewed International coauthorship
Yokoe T, Kawaguchi T, Kubo A, Kamei N, Teramoto A, Takao M, Pereira H
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA 2025.11
Authorship：Lead author, Corresponding author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1002/ksa.70184
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横江 琢示, 亀井 直輔
Journal of experimental orthopaedics 12 ( 3 ) e70393 2025.8
Authorship：Lead author, Last author, Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：John Wiley & Sons
To evaluate the accuracy of answers to clinical questions on the surgical treatment of chronic lateral ankle instability (CLAI) using ChatGPT-4 as a reference for consensus statements developed by the ESSKA-AFAS Ankle Instability Group (AIG). This study simulated the clinical settings where non-expert clinicians treat patients with CLAI./The large language model (LLM) ChatGPT-4 was used on 10 February 2025 to answer a total of 17 questions regarding the surgical management of CLAI that were developed by the ESSKA-AFAS AIG. The ChatGPT responses were compared with the consensus statements developed by ESSKA-AFAS AIG. The consistency and accuracy of the answers by ChatGPT as a reference for the experts' answers were evaluated. The consistency of ChatGPT's answers to the consensus statements was assessed by the question, 'Is the answer by ChatGPT agreement with those by the experts? (Yes or No)'. Four scoring categories: Accuracy, Overconclusiveness (proposed recommendation despite the lack of consensus), Supplementary (additional information not covered by the consensus statement), and Incompleteness, were used to evaluate the quality of ChatGPT's answers./Of the 17 questions on the surgical management of CLAI, 11 answers (64.7%) were agreement with the consensus statements by the experts. The percentages of ChatGPT's answers that were considered 'Yes' in the Accuracy and Supplementary were 64.7% (11/17) and 70.6% (12/17), respectively. The percentages of ChatGPT's answers that were considered "No" in the Overconclusiveness and Incompleteness were 76.5% (13/17) and 88.2% (15/17), respectively./The present study showed that ChatGPT-4 could not provide answers to queries on the surgical management of CLAI, such as foot and ankle experts. However, ChatGPT also showed its promising potential for its application when managing patients with CLAI./Level Ⅳ.
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The assessment of ChatGPT‐4's performance compared to expert's consensus on chronic lateral ankle instability Reviewed International coauthorship
Takuji Yokoe, Giulia Roversi, Nuno Sevivas, Naosuke Kamei, Pedro Diniz, Helder Pereira
Journal of Experimental Orthopaedics 12 ( 3 ) e70393 2025.8
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1002/jeo2.70393
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Nakamura Y, Yokoe T, Ouchi K, Funamoto T, Kimura H, Hamada K, Arakawa H, Chosa E, Kamei N
BMC geriatrics 25 ( 1 ) 500 2025.7
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Springer Science and Business Media LLC
Background
The efficacy of supplementation with branched-chain amino acids (BCAAs) and vitamin D with exercise in elderly people remains unclear. This study aimed to examine whether the combination of exercise and supplementation with BCAA- and vitamin D-containing high-protein food would be effective in improving soft lean mass and physical functions in elderly people with impaired physical functions.
Methods
This 12-week interventional study recruited elderly people ≥ 60 years of age with impaired physical activity (locomotive syndrome, LS). The participants were assigned to one of the following three groups: exercise group (group EX, n = 46), exercise with supplementation of BCAA- and vitamin D-containing high-protein food group (group EF, n = 45), and control group (group C, n = 31). Subjects in group EX were instructed to perform locomotion training, and those in group EF were instructed to consume high-protein test food in addition to locomotion training. The soft lean mass, a self-administered questionnaire (Geriatric Locomotive Function Scale-25, GLFS-25) and physical tests (stand-up test, two-step test), and the value of 25OH vitamin D were compared among the three groups after three months of intervention.
Results
There were no significant declines in soft lean mass in group EF, while significant declines were detected in the other two groups. There were significant differences in the stand-up test scores among the three groups (p = 0.03). A post-hoc analysis showed a significant difference between groups C and EF. There was a significant difference in the two-step test scores among the three groups (p = 0.004). A post-hoc analysis showed significant differences between groups C and EX, and between groups C and EF. There were no significant differences in the GLFS-25 scores among the groups. There was a significant increase in the value of 25OH vitamin D after three months in group EF (p < 0.001).
Conclusions
This study showed that BCAA and vitamin D supplementation with exercise in elderly subjects with declining physical functions resulted in maintenance of soft lean mass, improvement in physical functions (stand-up test score and two-step test), and an increase in 25OH vitamin D. -
横江 琢示, 亀井 直輔
Foot & ankle orthopaedics 10 ( 3 ) 24730114251352494 2025.7
Authorship：Lead author, Last author, Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Sage
There are few studies that have evaluated whether large language models, such as ChatGPT, can provide accurate guidance to clinicians in the field of foot and ankle surgery. This study aimed to assess the accuracy of ChatGPT's responses regarding ankle cartilage repair by comparing them with the consensus statements from foot and ankle experts as a standard reference./The open artificial intelligence (AI) model ChatGPT-4 was asked to answer a total of 14 questions on debridement, curettage, and bone marrow stimulation for ankle cartilage lesions that were selected at the 2017 International Consensus Meeting on Cartilage Repair of the Ankle. The ChatGPT responses were compared with the consensus statements developed in this international meeting. A Likert scale (scores, 1-5) was used to evaluate the similarity of the answers by ChatGPT to the consensus statements. The 4 scoring categories (Accuracy, Overconclusiveness, Supplementary, and Incompleteness) were also used to evaluate the quality of ChatGPT answers, according to previous studies./The mean Likert scale score regarding the similarity of ChatGPT's answers to the consensus statements was 3.1 ± 0.8. Regarding the results of 4 scoring categories of the ChatGPT answers, the percentages of answers that were considered "yes" in the Accuracy, Overconclusiveness, Supplementary, and Incompleteness were 71.4% (10/14), 35.7% (5/14), 78.6% (11/14), and 14.3% (2/14), respectively./This study showed that ChatGPT-4 often provides responses that diverge from expert consensus regarding surgical treatment of ankle cartilage lesions./Level V, expert opinion.
Presentations 【 display / non-display 】
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柔道競技における膝前十字靭帯損傷の特徴
森田雄大、田島卓也、山口奈美、横江琢示、帖佐悦男
第49回九州膝関節研究会 2024.3.16
Event date： 2024.3.16
Presentation type：Oral presentation (general)
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CT画像による腓骨筋腱溝の形態学的評価
横江琢示、田島卓也、山口奈美、森田雄大、帖佐悦男
第10回九州足の外科研究会 2024.3.2
Event date： 2024.3.2
Presentation type：Oral presentation (general)
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Predicting The Clinical Decision Limits of Locomotive Syndrome from The Screening Questionnaire Using Machine Learning International conference
Yoichiro Yamaguchi、Hiroyuki Imazato、Takuji Yokoe、Yudai Morita、Takuya Tajima、Etsuo Chosa
ORS2024 ANNUAL MEETING
Event date： 2024.2.2 - 2024.2.6
Presentation type：Poster presentation
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A possible Cause of Articular Cartilage Degeneration in the Acute Phase after Anterior Cruciate Ligament Reconstruction International conference
Yudai Morita、Takuya Tajima、Nami Yamaguchi、Takuji Yokoe、Etsuo Chosa
ORS2024 ANNUAL MEETING
Event date： 2024.2.2 - 2024.2.6
Presentation type：Poster presentation
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徒手前方引き出しテストとストレス超音波検査による足関節回旋不安定性の関係
横江琢示、田島卓也、山口奈美、大田智美、長澤誠、森田雄大、帖佐悦男
第35回九州・山口スポーツ医・科学研究会 2023.12.9
Event date： 2023.12.9
Presentation type：Oral presentation (general)