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Organization for Promotion of Research and Industry-Academic Regional Collaboration Institute for Tenure Track Promotion |
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Title |
Associate Professor |
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Contact information |
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Related SDGs |
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FUKUNAGA Keisuke
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Degree 【 display / non-display 】
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Ph.D. in Engineering ( 2014.3 The University of Electro-Communications )
Research Interests 【 display / non-display 】
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Directed evolution
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Biotechnology
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Synthetic Biology
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RNA aptamer
Research Areas 【 display / non-display 】
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Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Biofunction and bioprocess engineering
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Nanotechnology/Materials / Bio chemistry
Professional Memberships 【 display / non-display 】
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日本生物工学会
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日本核酸化学会
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「細胞を創る」研究会
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日本化学会・生体機能関連化学部会
Papers 【 display / non-display 】
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In Vitro Evolution of the Adenosine A2A Receptor Based on an Antagonist Binding Using a Ribosome Display Reviewed International journal
Genki Fukasawa, Yuma Matsuoka, Duy Phuoc Tran, Haruka Nishigaki, Keisuke Fukunaga, Takayoshi Watanabe, Tomohiro Doura, Naohiro Terasaka, Ako Kagawa, Takeshi Murata, Akio Kitao, Shigeki Kiyonaka, Tomoaki Matsuura
Journal of the American Chemical Society 2026.3
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1021/jacs.6c02372
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A competitive fluorescence immunoassay based on intermolecular quenching using an N-terminally fluorescent-labeled IgG antibody Reviewed International journal
Keisuke Fukunaga, Takayoshi Watanabe, Takahiro Hohsaka
Biochemical and Biophysical Research Communications 808 153449 2026.2
Authorship：Lead author, Corresponding author Language：English Publishing type：Research paper (scientific journal)
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A Competitive Fluorescence Immunoassay Based on Intermolecular Quenching Using an N-Terminally Fluorescent-Labeled IgG Antibody International journal
Keisuke Fukunaga, Takayoshi Watanabe, Takahiro Hohsaka
bioRxiv 2026.1
Authorship：Lead author, Corresponding author Language：English Publishing type：Research paper (scientific journal)
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In vitro evolution of adenosine A2A receptor based on an antagonist binding using ribosome display International journal
Genki Fukasawa, Yuma Matsuoka, Duy Phuoc Tran, Keisuke Fukunaga, Haruka Nishigaki, Tomohiro Doura, Naohiro Terasaka, Ako Kagawa, Takeshi Murata, Akio Kitao, Shigeki Kiyonaka, Tomoaki Matsuura
ChemRxiv 2025.7
Language：English Publishing type：Research paper (scientific journal)
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Structural insights into lab-coevolved RNA–RBP pairs and applications of synthetic riboswitches in cell-free system Reviewed International journal
Keisuke Fukunaga, Takamasa Teramoto, Momoka Nakashima, Toshitaka Ohtani, Riku Katsuki, Tomoaki Matsuura, Yohei Yokobayashi, Yoshimitsu Kakuta
Nucleic Acids Research 53 ( 6 ) 2025.3
Authorship：Lead author, Corresponding author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1093/nar/gkaf212
DOI： 10.1093/nar/gkaf212
Other Link： https://doi.org/10.1093/nar/gkaf212
MISC 【 display / non-display 】
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人工進化が生んだ超高親和性RNA–タンパク質ペア
福永 圭佑, 寺本 岳大
B&Iバイオサイエンスとインダストリー 83 ( 6 ) 476 - 477 2025.11
Authorship：Lead author, Corresponding author Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (other)
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若手研究者からのメッセージ
福永 圭佑
日本化学会 バイオテクノロジー部会 ニュースレター 25 ( 2 ) 10 - 14 2022
Authorship：Lead author, Corresponding author Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (other)
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PD-SELEX法を用いた直交性RNA-RBPペアの指向性進化
福永 圭佑
日本化学会 生体機能関連化学部会 ニュースレター 36 ( 2 ) 10 - 14 2021
Authorship：Lead author, Corresponding author Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (other)
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Site-specific N-terminal Fluorescent Labeling of Unprotected Peptides Reviewed
Keisuke Fukunaga, Takayoshi Watanabe, and Takahiro Hohsaka
Peptide Science 2015 2016
Authorship：Lead author Language：English Publishing type：Article, review, commentary, editorial, etc. (international conference proceedings)
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An Artificial Molecule-Peptide Hybrid Discovered via the 10BASEd-T Binds to the Substrate-Binding Site of Glutathione S-Transferase Reviewed
Keisuke Fukunaga, Takaaki Hatanaka, Yuji Ito, and Masumi Taki
Peptide Science 2013 2014
Authorship：Lead author, Corresponding author Language：English Publishing type：Article, review, commentary, editorial, etc. (international conference proceedings)
Presentations 【 display / non-display 】
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Development of synthetic riboswitches using in vitro selected RNA aptamers International conference
Keisuke Fukunaga, Takamasa Teramoto, Yoshimitsu Kakuta, Tomoaki Matsuura, Yohei Yokobayashi
Pacifichem 2025 2025.12
Event date： 2025.12.15 - 2025.12.20
Language：English Presentation type：Oral presentation (general)
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Evaluation of Targeted Protein Degradation by Genetically Encoded RNA- PROTACs Using a Dual Reporter System International conference
Keisuke Fukunaga, Kayo Furuichi, Yang Yinjie, Tomoaki Matsuura, Yohei Yokobayashi
ISNAC2025 2025.11
Event date： 2025.11.12 - 2025.11.14
Language：English Presentation type：Poster presentation
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Screening RNA-Phospholipid Membrane Vesicle Interactions using SELEX: Implications for Protocell Assembly International conference
Arshjot Mann, Keisuke Fukunaga, Tomoaki Matsuura
BB2025 2025.11
Event date： 2025.11
Language：English Presentation type：Poster presentation
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Developing red-light-responsive RNA riboswitches – Towards minimal, genetically encodable optogenetic tools International conference
Zimu Zhang, Keisuke Fukunaga, Tomoaki Matsuura
BB2025 2025.11
Event date： 2025.11
Language：English Presentation type：Poster presentation
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合成リボスイッチ：設計原理と遺伝子発現制御への応用 Invited
福永 圭佑
第47回蛋⽩質と酵素の構造と機能に関する九州シンポジウム 2025.9.24
Event date： 2025.9.24 - 2025.9.26
Language：Japanese Presentation type：Oral presentation (invited, special)
Works 【 display / non-display 】
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Crystal structure of the L7Ae derivative protein LS12 in RNA-free state
Takamasa Teramoto, Momoka Nakshima, Keisuke Fukunaga, Yohei Yokobayashi, Yoshimitsu Kakuta
2025.4.2
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Crystal structure of the L7Ae derivative protein LS12 in complex with its co-evolved target CS2 RNA
Takamasa Teramoto, Momoka Nakshima, Keisuke Fukunaga, Yohei Yokobayashi, Yoshimitsu Kakuta
2025.4.2
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Crystal structure of the L7Ae derivative protein LS4 in complex with its co-evolved target CS1 RNA
Takamasa Teramoto, Momoka Nakshima, Keisuke Fukunaga, Yohei Yokobayashi, Yoshimitsu Kakuta
2025.4.2
Awards 【 display / non-display 】
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第13回新化学技術研究奨励賞
2024.6 公益社団法人新化学技術推進協会（JACI）
本人
Award type：Award from publisher, newspaper, foundation, etc.
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支部長賞
2023.7 日本生物工学会東日本支部
本人
Award type：Award from Japanese society, conference, symposium, etc.
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部会講演賞
2021.9 第15回バイオ関連化学シンポジウム
本人
Award type：Award from Japanese society, conference, symposium, etc.
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FIBER核酸化学 若手講演賞
2021.8 FIBER日本核酸化学会若手フォーラム
本人
Award type：Award from Japanese society, conference, symposium, etc.
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若手口頭発表優秀賞
2013.11 第4回 アジア−太平洋国際ペプチドシンポジウム
本人
Award type：Award from international society, conference, symposium, etc.