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Akioka T., Terada N., Takamori H., Kamimura T., Mukai S., Kamoto T.
Urology Case Reports 40 101925 2022年1月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Urology Case Reports
von Hippel–Lindau (VHL) disease is an autosomal dominant hereditary disease with benign and malignant tumors occurring in various organs including the kidneys. In patients with renal cell carcinoma (RCC) lesions in both kidneys, it is difficult to determine the treatment strategy. We report a case of VHL disease with RCC treated via partial nephrectomy after 6 months of axitinib therapy. Then, the patient continued to receive low-dose axitinib therapy without any signs of tumor progression for 3 years after surgery. Axitinib combined with surgery might be a treatment option for patients with VHL disease harboring bilateral RCC.
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Ito K., Takamori H., Akioka T., Hida T., Okabe K., Kida K., Terada N., Kamimura T., Mukai S., Kamoto T.
Acta Urologica Japonica 67 ( 7 ) 309 - 312 2021年7月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Acta Urologica Japonica
We report a case of Stauffer syndrome-like findings in a patient with metastatic renal carcinoma treated by surgery and molecular targeted therapy. The patient was a 58-year-old woman diagnosed with renal carcinoma with multiple metastases. She had hepatosplenomegaly and hepatic dysfunction with elevated serum liver enzyme and IL-6 levels. Treatment with temsirolimus and axitinib reduced the size of the local and metastatic tumors and simultaneously improved the hepatosplenomegaly. The local tumor was excised by laparoscopic nephrectomy, treated with axitinib and then with nivolumab. With the reduction in the metastatic tumor size, scrum liver enzyme and IL-6 levels decreased. It was suggested that molecular targeted therapy is an effective treatment when the findings of metastatic renal cell carcinoma, are similar to those of Stauffer syndrome.
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Matsuoka H., Tsubouchi K., Tanaka M., Haga N., Yamaguchi T., Koikawa Y., Miyazato M., Saito S., Kihara T., Miyata Y., Mochizuki Y., Sakai H., Enokida H., Hayami H., Nakagawa M., Mori K.I., Shin T., Kamimura T., Mukai S., Kamoto T., Inokuchi J., Eto M., Fujimoto N., Suekane S., Matsuo M., Igawa T., Tobu S., Noguchi M., Nishi K., Kamba T., Ishii T.
Nishinihon Journal of Urology 82 ( 86 ) 570 - 578 2021年2月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Nishinihon Journal of Urology
[Objective] To investigate the postoperative long-term prognosis and the factors predicting the renal function of patients with reflux nephropathy. (Materials and methods) This study examined s-Cr, urinary protein and blood pressure of patients who had undergone anti-reflux surgery 10 years earlier. It also calculated the postoperative estimated glomerular filtration rate (eGFR) and examined the correlation between the eGFR and preoperative factors, while also analyzing factors associated with long-term prognosis. [Results) The study population was 51 infants (37 boys and 14 girls). The mean age of the patients at surgery was 3.41 ± 3.61 years. The postoperative eGFR was a mean of 90.27 ± 20.42 ml/min/1.73 m2and was primarily correlated with age, primary diagnosis, reflux grade, degree of renal parenchymal damage, s-Cr abnormality, and proteinuria at baseline. A total of 20 patients had chronic kidney disease. Multiple regression analysis of these factors revealed that an older age (P=0.0021), a reflux grade of ≥ 8 (P=0.0134), and the degree of renal parenchymal damage (group≥2b, P<0.0001) were significantly associated with the long-term postoperative prognosis of reflux nephropathy. Using these three factors, this study derived a multiple regression equation for estimating eGFR in the 10th year after surgery. [Conclusions] Age, reflux grade, and degree of renal parenchymal damage at baseline were factors that affected long-term postoperative prognosis of reflux nephropathy. Patients with high-grade reflux (reflux grade≥8) and severe renal parenchymal damage (group≥2b) were more likely to show a reduced CKD level at 10 years after anti-reflux surgery.
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Kimura S, Terada N, Akioka T, Nakahara T, Nagano M, Yamamoto K, Akiyama Y, Sato Y, Otsuka I, Kimura T, Hida T, Okabe K, Takamori H, Kida K, Kamimura T, Mukai S, Kamoto T
Hinyokika kiyo. Acta urologica Japonica 66 ( 3 ) 91 - 96 2020年3月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：泌尿器科紀要刊行会
A 73-year-old Japanese man visited the urology clinic with the chief complaint of gross hematuria in June 2015. His prostate specific antigen (PSA) level was 146.7 ng/ml and he was diagnosed with prostate adenocarcinoma with a Gleason Score of 5+4. With bone metastasis in the right femur (cT3aN0M1), he was treated by orchiectomy and bicalutamide. He had gross hematuria in October 2017 and a prostate tumor was detected by computed tomography (CT) and magnetic resonance imaging without increasing PSA levels. Prostate re-biopsy showed prostate neuroendocrine carcinoma and local radiation therapy (74 Gy) was performed. Follow-up CT revealed a left adrenal tumor with a positive positron emission tomographic scan in October 2018. Under the diagnosis of metastatic neuroendocrine carcinoma, chemotherapy using cisplatinum and etoposide was performed. The tumor shrunk after five courses of treatment, followed by regrowth in April 2019. Radiation therapy (50 Gy) was added to the left adrenal tumor and it shrunk again. However, a left retroperitoneal tumor was detected in July 2019 and it was resected under laparoscopic surgery and diagnosed as metastatic neuroendocrine carcinoma. Since then, no recurrence has been observed.
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Kimura S., Terada N., Akioka T., Nakahara T., Nagano M., Yamamoto K., Akiyama Y., Sato Y., Otsuka I., Kimura T., Hida T., Okabe K., Takamori H., Kida K., Kamimura T., Mukai S., Kamoto T.
Acta Urologica Japonica 66 ( 3 ) 91 - 96 2020年3月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Acta Urologica Japonica
A 73-year-old Japanese man visited the urology clinic with the chief complaint of gross hematuria in June 2015. His prostate specific antigen (PSA) level was 146.7 ng/ml and he was diagnosed with prostate adenocarcinoma with a Gleason Score of 5 + 4. With bone metastasis in the right femur (cT3aN0Ml), he was treated by orchiectomy and bicalutamidc. He had gross hematuria in October 2017 and a prostate tumor was detected by computed tomography (CT) and magnetic resonance imaging without increasing PSA levels. Prostate re-biopsy showed prostate neuroendocrine carcinoma and local radiation therapy (74 Gy) was performed. Follow-up CT revealed a left adrenal tumor with a positive positron emission tomographic scan in October 2018. Under the diagnosis of metastatic neuroendocrine carcinoma, chemotherapy using cisplatinum and etoposide was performed. The tumor shrunk after five courses of treatment, followed by re-growth in April 2019. Radiation therapy (50 Gy) was added to the left adrenal tumor and it shrunk again. However, a left retroperitoneal tumor was detected in July 2019 and it was resected under laparoscopic surgery and diagnosed as metastatic neuroendocrine carcinoma. Since then, no recurrence has been observed.
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術後の急変・危険サイン１
上村敏雄、賀本敏行
泌尿器ケア 20 ( 1 ) 12 - 20 2015年1月
記述言語：日本語 掲載種別：記事・総説・解説・論説等（商業誌、新聞、ウェブメディア） 出版者・発行元：メディカ出版
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小児泌尿器科
上村 敏雄
Highlight of EAU 2012年5月
記述言語：日本語 掲載種別：研究発表ペーパー・要旨（全国大会，その他学術会議） 出版者・発行元：RichHill Medical Inc.
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陰嚢水瘤根治術 （共著）
上村敏雄, 長野正史
臨床泌尿器科 64 ( 2 ) 121 - 127 2010年2月
記述言語：日本語 掲載種別：記事・総説・解説・論説等（学術雑誌） 出版者・発行元：医学書院
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小児原発性膀胱尿管逆流症の治療指針（共著）
長野正史, 上村敏雄, 月野浩昌
西日本泌尿器科 70 ( 4 ) 183 - 186 2008年4月
記述言語：日本語 掲載種別：記事・総説・解説・論説等（学術雑誌） 出版者・発行元：日本泌尿器科学会西日本支部
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Maeda K., Osada Y., Hamasuna R., Kodama S., Shitamura T., Mukai S., Yakushiji K., Kamimura T., Takahashi N., Iwamoto H., Shibata N., Wakeda H., Ide H., Takehara T., Nagano M., Itoi T., Oda A., Kobayashi T., Yamashita Y., Nagata T., Nose K., Hasui Y., Kitada S., Senou K., Shinkawa T., Nagatomo K., Saito Y., Miyazaki N., Tanada T., Ohfuji T., Koriyama K., Nishi S., Yamaguchi T., Murakami N., Takehara A., Uehara K., Muraoka K., Ikei Y., Yanagita T., Ebihara K.
Nishinihon Journal of Urology 60 ( 10 ) 728 - 732 1998年
記述言語：日本語 掲載種別：記事・総説・解説・論説等（大学・研究所紀要） 出版者・発行元：Nishinihon Journal of Urology
Clinical statistical studies on 13,618 new outpatients, 5,030 inpatients and 4,324 operative procedures at the Urological Department of Miyazaki Medical College from 1977 to 1996 revealed the following results: 1) The most common diseases among the male outpatients were prostate tumors (17.7%), urolithiasis (12.7%) and urogenital anomalies (11.9%). Those among the female outpatients were inflammatory diseases (16.2%), urolithiasis (10.7%) and urogenital tumors (9.8%). 2) The major diseases among inpatients were urogenital tumors (35.8%), urogenital anomalies (16.7%) and urolithiasis (13.2%). 3) Operations were performed 4,324 times. The three most common surgical procedures were TUR-Bt (656 times), orchiopexy (354 times) and TUR- P (281 times).
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移植腎尿管新吻合部狭窄に対してバルーン拡張、尿管結石に対してTULを施行した1例
上村 敏雄
第38回九州腎移植研究会
開催年月日： 2016年7月30日
記述言語：日本語 会議種別：口頭発表（一般）
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1才児に対して腹腔鏡下腎摘除術を施行した一例
上村敏雄
第13回九州小児泌尿器科研究会 (沖縄県) 九州小児泌尿器科研究会
開催年月日： 2016年2月13日
記述言語：日本語 会議種別：口頭発表（一般）
開催地：沖縄県
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腹腔鏡下根治的腎摘除術における内視鏡下血管クリップ（ブルドック鉗子）の応用
上村敏雄、賀本敏行
第28回日本内視鏡外科学会総会 (大阪府大阪市) 日本内視鏡外科学会
開催年月日： 2015年12月10日 - 2015年12月12日
記述言語：日本語 会議種別：シンポジウム・ワークショップ パネル（指名）
開催地：大阪府大阪市
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腹部手術歴のある腹腔鏡下膀胱全摘術
上村敏雄、賀本敏行
第29回日本泌尿器内視鏡学会総会 (東京都新宿区) 日本泌尿器内視鏡学会
開催年月日： 2015年11月19日 - 2015年11月21日
記述言語：日本語 会議種別：シンポジウム・ワークショップ パネル（指名）
開催地：東京都新宿区
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小児外傷性完全尿管断裂の１例
上村 敏雄
第11回九州小児泌尿器研究会 (大分県大分市) 九州小児泌尿器研究会
開催年月日： 2014年2月15日
記述言語：日本語 会議種別：口頭発表（一般）
開催地：大分県大分市