SUEYOSHI Masuo

写真a

Affiliation

Faculty of Agriculture Department of Veterinary Science

Title

Professor

External Link

Degree 【 display / non-display

  • 学位(獣医学)  ( 1992.9   北海道大学 )

  • 農学修士 ( 1983.3   宮崎大学 )

  • 農学学士 ( 1981.3   宮崎大学 )

Research Areas 【 display / non-display

  • Life Science / Veterinary medical science

  • Life Science / Gastroenterology

  • Life Science / Veterinary medical science

  • Life Science / Animal production science

 

Papers 【 display / non-display

  • The current porcine epidemic diarrhea (PED) situation in Japan Invited

    Masuo Sueyoshi

    Thai J Vet Med.   53 ( 2 )   S5 - S6   2023.6

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  • Farm Biosecurity ~Disinfection~ (Cattle) Invited Reviewed

    Masuo Sueyoshi

    The Journal of Farm Animal in Infectious Disease   12 ( 1 )   1 - 9   2023.1

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

    The basics of farm biosecurity are: (1) No bring pathogens into the farm, (2) No spread pathogens on the farm, and (3) No take pathogens out of the farm. For this purpose, it is important to restrict the entry and delivery of livestock, vehicles, people, livestock materials, etc. entering and leaving the farm, or we need to be thoroughly disinfected. "Disinfection" in it is ambiguous, and effective "disinfection" is necessary. Now that we have become "with coronavirus", the term and equipment of "disinfection" are everywhere in daily life. However, in some situations, "shedding" by "flushing and washing" is more effective than "disinfecting". The phenomenon is the same in the livestock industry. Here I outline the basic stages of an effective "disinfection" method.

  • Prevalence of equine proliferative enteropathy in Hidaka district, Hokkaido, over five seasons Reviewed

    Hidekazu NIWA, Toru HIGUCHI, Seiichi FUJII, Yuta KINOSHITA, Eri UCHIDA-FUJII, Masuo SUEYOSHI, Toshio NUKADA, Takanori UENO

    Journal of Equine Science   33 ( 4 )   71 - 74   2023.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    Equine proliferative enteropathy (EPE) is an equine infectious disease that can lead to severe weight loss and hyperplasia of the intestinal mucosa due to infection with Lawsonia intracellularis. In this study, we investigated the prevalence of EPE in a major Thoroughbred breeding area: Hidaka district, Hokkaido, Japan. Of the 252 symptomatic horses that we tested, 192 EPE cases (76.2%), including 8 fatal cases, were confirmed from April 2015 to March 2020 by etiological and/or serological investigation. Most of the EPE cases were observed in foals (88.5%), with fewer cases in yearlings (7.3%) and adults (4.2%). Asymptomatic infection was observed in 62.9% of the horses kept with affected horses. These results suggest that EPE is an enzootic disease in Hidaka district.

    DOI: https://doi.org/10.1294/jes.33.71

    DOI: https://doi.org/10.1294/jes.33.71

  • The presence of adhesion factors NOX, α-enolase, TrmFO, P27, and VpmaX in Mycoplasma bovis wild isolates in Japan Reviewed

    Shitamori F., Uemura R., Kanda T., Sueyoshi M.

    Open Veterinary Journal   12 ( 6 )   782 - 786   2022.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    Background: Mycoplasma bovis causes various diseases such as bronchopneumonia, otitis media, arthritis, and mastitis in cattle. Mycoplasma bovis is often isolated from the deep pharynges of healthy cattle and is generally considered not to cause clinical symptoms while in the upper respiratory tract. In mycoplasma infections, adhesion to the host cells is a crucial step. In recent years, five new adhesins, NOX, α-enolase, TrmFO, P27, and VpmaX, have been reported in M. bovis strains from pneumonia cases. However, the presence of these adhesins in wild isolates has not been established.
    Aim: This study aimed to investigate the presence of these adhesin genes in wild isolates isolated from cattle nasal cavities and lesion sites (pneumonia, otitis media, arthritis, and mastitis) in various regions in Japan and clarify the relationship between adhesion and the symptoms caused by M. bovis infection.
    Methods: A total of 141 M. bovis wild isolates isolated from nasal cavities (healthy or sick cattle), lungs with pneumonia, ears with otitis media, joint fluids of arthritic animals, and milk of mastitic animals. Mycoplasma bovis type strain PG45 was also used. Specific polymerase chain reaction reactions were performed to detect nox, α-enolase, trmFO, P27, and vpmaX, which are adhesins of M. bovis.
    Results: This study reports 139 M. bovis wild isolates were positive for nox, α-enolase, trmFO, P27, and vpmaX, while two isolates each lacked α-enolase or P27 genes. Mycoplasma bovis PG45 also had all five adherens genes.
    Conclusion: Almost all M. bovis wild isolates possessed all nox, α-enolase, trmFO, P27, and vpmaX genes regardless of the lesion site or region of origin. This means no relationship was found between the presence of the five adhesins and lesion sites in M. bovis and M. bovis isolated from the nasal cavities of asymptomatic cattle have the same numbers and types of adhesins as isolates from symptomatic lesion sites (pneumonia, otitis media, arthritis, and mastitis). This suggests that not only M. bovis isolates from pulmonary lesions, but also M. bovis existing in the nasal cavity has the potential to causes symptoms in the host.

    DOI: 10.5455/OVJ.2022.v12.i6.1

  • Histopathological findings of the nasopharynx-associated lymphoid tissue of pigs with porcine circovirus 2 and porcine reproductive and respiratory syndrome virus coinfection Reviewed

    Toyama K., Hirai T., Sueyoshi M., Zhou Z., Niazii A. M., Kawaguchi N., Fuke N., Yamaguchi Y.

    J. Vet. Med. Sci.   84 ( 11 )   1536 - 1542   2022.10

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:JAPANESE SOCIETY OF VETERINARY SCIENCE  

    Porcine circovirus 2 (PCV2) causes porcine circovirus-associated disease, and coinfection
    with porcine reproductive and respiratory syndrome virus (PRRSV) severely affects the
    pig breeding industry. Both viruses target the macrophages in lymphoid tissues. Various porcine
    pathogens enter via the nasal cavity, and the nasopharynx-associated lymphoid tissue (NALT) acts
    as the mucosal immune system. However, the pathological analysis has not progressed. This study
    aimed to histologically examine the NALT of pigs with suspected PCV2 and PRRSV infections. Six pigs
    were subjected to necropsy, and their NALT, tonsils, and mesenteric lymph nodes were collected.
    Macrophages, lymphocytic depletion, multinucleated giant cells, intracytoplasmic inclusion bodies,
    and neutrophil infiltration increased in the NALT. In situ hybridization revealed positive signals for
    PCV2 in the NALT of all pigs and PRRSV in the NALT of three pigs. PCV2-positive macrophages were
    mainly identified in the follicles, whereas PRRSV-positive tissues were found primarily around the
    crypt and directly below the epithelium. Quantitative PCR revealed 108–1010 copies of PCV2 DNA/μL
    and 102–104 copies of PRRSV DNA/μL in the NALT. Therefore, both PCV2 and PRRSV were detected in
    the NALT of pigs. In conclusion, the infection and replication of both viruses in the NALT and tonsils
    may suppress host immunity and promote co-infection with other pathogens.

    DOI: 10.1292/ jvms.22-0231

    Other Link: https://jsvetsci.jp/jvms/

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Books 【 display / non-display

  • 動物病理学各論第3版

    末吉益雄他( Role: Joint author)

    文永堂  2021.3 

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    Language:Japanese Book type:Textbook, survey, introduction

  • 家禽疾病学. 第2版

    末吉益雄他( Role: Joint author)

    鶏病研究会  2021.3 

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    Total pages:292   Responsible for pages:60-63   Language:Japanese Book type:Textbook, survey, introduction

  • 動物の衛生 第2版

    末吉益雄他( Role: Edit)

    文永堂  2020.3 

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    Total pages:295   Responsible for pages:1-2, 2-6, 6-11, 35-36, 86-105,135-145, 165-171, 218-221.   Language:Japanese Book type:Textbook, survey, introduction

    Other Link: https://www.amazon.co.jp/%E5%8B%95%E7%89%A9%E3%81%AE%E8%A1%9B%E7%94%9F-%E7%AC%AC2%E7%89%88-%E6%9C%AB%E5%90%89-%E7%9B%8A%E9%9B%84/dp/4830041390/ref=sr_1_2?hvadid=275524130572&hvdev=c&jp-ad-ap=0&keywords=%E5%8B%95%E7%89%A9%E3%81%AE%E8%A1%9B%E7%94%9F&qid=1583653958&sr=8-2

  • 養豚用語事典

    末吉益雄他( Role: Joint author)

    日本養豚学会編 創文  2019.3 

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    Language:Japanese Book type:Textbook, survey, introduction

    養豚関連の衛生と疾病に関する専門用語について概説した。

  • 動物感染症学 第4版

    末吉益雄他( Role: Joint author)

    近代出版  2019.3 

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    Responsible for pages:p.184-186, p.179-180, p.178-179, p.177-178, p.118-119, p.211   Language:Japanese Book type:Textbook, survey, introduction

    動物の感染症の腸腺腫症候群、豚赤痢、豚のサルモネラ症、豚の大腸菌症、鶏の大腸菌症、子牛の大腸菌性下痢について概説した。

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MISC 【 display / non-display

  • 口蹄疫発生現場の実態と繰り返さないためには. Invited

    末吉益雄

    JASV会報   32 ( 1 )   2 - 5   2023.3

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:緑書房  

  • 腸管の仕組みと大腸菌症の基礎 Invited

    末吉益雄

    養豚界   57 ( 1 )   28 - 34   2022.1

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:緑書房  

  • 豚熱防疫~ゴールの見えない多事多難な道のり③ Invited

    末吉益雄

    養豚の友   630 ( 11 )   42 - 45   2021.10

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:日本畜産振興会  

  • 豚熱防疫~ゴールの見えない多事多難な道のり② Invited

    末吉益雄

    養豚の友   630 ( 10 )   36 - 39   2021.9

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:日本畜産振興会  

  • 豚熱防疫~ゴールの見えない多事多難な道のり① Invited

    末吉益雄

    養豚の友   630 ( 9 )   18 - 22   2021.8

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:日本畜産振興会  

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Presentations 【 display / non-display

  • The current porcine epidemic diarrhea (PED) situation in Japan International conference

    Sueyoshi M.

    2023.6.5 

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    Event date: 2023.6.4 - 2023.6.7

    Language:English   Presentation type:Oral presentation (general)  

    Country:Thailand  

  • Methicillin-resistant Staphylococcus aureus selective media is unsuitable for methicillin-resistant S. pseudintermedius detection. International conference

    Sakaguchi K., Uemura R. Sueyoshi M.

    The 21st Federation of Asian Veterinary Associations (FAVA) Congress  (Fukuoka, Japan)  2022.11.11  Federation of Asian Veterinary Associations (FAVA) Congress

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    Event date: 2022.11.10 - 2022.11.13

    Language:English   Presentation type:Poster presentation  

    Venue:Fukuoka, Japan   Country:Japan  

  • メチシリン耐性黄色ブドウ球菌用選択培地はメチシリン耐性Staphylococcus pseudintermedius分離に不適である

    坂口海飛, 上村涼子, 末吉益雄.

    令和4年度日本産業動物獣医学会  (大分市(オンライン))  2022.9.20  日本産業動物獣医学会

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    Event date: 2022.9.20 - 2022.10.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大分市(オンライン)  

  • 培養基中の植物性蛋白質は豚の浮腫病由来志賀毒素産生性大腸菌の志賀毒素産生を増加させる

    永田 舜, 上村涼子, 末吉益雄.

    令和4年度日本産業動物獣医学会  (大分市(オンライン))  2022.9.20  日本産業動物獣医学会

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    Event date: 2022.9.20 - 2022.10.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大分市(オンライン)  

  • 豚の浮腫病由来志賀毒素産生性大腸菌の増殖および毒素放出に与える生菌製剤各構成菌の影響

    永田 郁, 上村涼子, 末吉益雄

    令和4年度日本産業動物獣医学会  (大分市(オンライン))  2022.9.20  日本産業動物獣医学会

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    Event date: 2022.9.20 - 2022.10.3

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:大分市(オンライン)  

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Awards 【 display / non-display

  • 九獣連会長賞

    2022.9   令和4年度日本産業動物獣医学会(九州地区)   培養基中の植物性蛋白質は豚の浮腫病由来志賀毒素産生性大腸菌の志賀毒素産生を増加させる

    永田 舜. 上村涼子, 末吉益雄.

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • JASV2020学生アワード受賞

    2021.1   日本養豚開業獣医師協会年次学会   豚由来マクロファージ内侵入サルモネラに対するフルオロキノロン系抗菌薬の殺菌効果

    黒田翔太、上村涼子、末吉益雄.

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 第163回日本獣医学会学術集会若手奨励賞

    2020.9   日本獣医学会学術集会   牛好中球へのMycoplasma bovis感作の影響

    上村悠祐、上村涼子、小林郁雄、末吉益雄.

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 第162回日本獣医学会学術集会第10回若手奨励賞

    2019.9   日本獣医学会学術集会   Mycoplasma bovis感作に対する牛肺胞マクロファージのサイトカイン発現応答

    甲斐慎二他

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 日本家畜臨床学会長賞受賞

    2017.11   日本家畜臨床学会   2010年に宮崎で発生した口蹄疫の防疫措置終了後に農場内に留置された家畜排泄物のウイルス残存性調査

    川嶌健司他

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

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Grant-in-Aid for Scientific Research 【 display / non-display

  • クリーン模範養豚場の作出

    2012.04 - 2015.03

    科学研究費補助金  挑戦的萌芽研究

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    Authorship:Principal investigator 

    安全な豚肉を食卓に届けるために。生産の場である養豚場環境の清浄化を模索する。消毒方法の見直し、豚舎器材の抗菌化について検討する。

  • 韓国に生息するキバノロの生体および生理機構の網羅的解明と潜在的感染症の疫学的調査

    2011.04 - 2014.03

    科学研究費補助金  基盤研究(B)

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    Authorship:Coinvestigator(s) 

    韓国に生息している原始的な反芻動物であるキバノロの生体及び生理機構を網羅的に解明し、系統発生学的に比較解析するとともに、人獣共通感染症や海外悪性伝染病の疫学調査を行い、その潜在的病態を把握する。

  • 分娩後早期の牛の発情同期化と、交配後非妊娠牛に対する適切な再同期化処置法の開発

    2007.04 - 2009.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Coinvestigator(s) 

    分娩後のVWP自発的繁殖待ち期間に牛の生殖器の修復や卵巣機能回復を検査し、個々の牛に応じた卵巣賦活や発情同期化処置を行う。分娩後早期の卵巣賦活による定時人工授精後、なるべく早期に妊娠診断を行い、非妊娠牛に対して、その時点での卵巣所見に適応した再同期化処置を行う。乳牛での分娩後85日、黒毛和種での80日までに2回の人工授精により75%の牛群妊娠率を目指す繁殖管理技術の開発を目指す。

  • 難培養性細菌トレポネーマを中心とした混合感染症のゲノム解析とその応用

    2005.04 - 2007.03

    科学研究費補助金  特定領域研究

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    Authorship:Coinvestigator(s) 

    伝染性の強い牛趾乳頭腫症の原因菌は未だ不明のままである。それらの病変部から種々の微生物が形態学的あるいは遺伝子学的に検出されているが、有意な病原体の分離はいまだにない。本課題では、病理形態遺伝子学的に病変部における局在を検索する。

  • 病原性大腸菌健康保菌動物摘発法の開発研究

    2003.04 - 2005.03

    科学研究費補助金  挑戦的萌芽研究

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    Authorship:Principal investigator 

    ヒトの腸管出血性大腸菌感染症の感染源は牛などの家畜がその一つとされている。しかし、ヒトに病原性のあるO157大腸菌などは牛に感染しても無症状であるため発見されにくい。そこで、それらの健康保菌動物を摘発する方法を開発する。

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Other research activities 【 display / non-display

  • 家畜疾病の病性鑑定

    2000.04

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    南九州地域を中心とした牛および豚の農場における不明疾病等について、農場主、管理獣医師から病性鑑定の依頼があった場合、その原因究明、疾病診断、治療あるいは予防について対応している。

Available Technology 【 display / non-display