TUNEYOSHI Isao

写真a

Affiliation

Faculty of Medicine School of Medicine Department of Medicine of Pathophysiological Diagnosis and Therapy, Anesthesiology and Intensive Care

Title

Professor

External Link

Degree 【 display / non-display

  • 博士(医学) ( 1996.3   鹿児島大学 )

  • 医学士 ( 1990.3   鹿児島大学 )

 

Papers 【 display / non-display

  • 術後の疼痛コントロールに難渋したブプレノルフィン貼付剤使用患者の一症例. Reviewed

    門田瑶子,山賀昌治,日髙康太郎,内村修二,渡部由美,恒吉勇男

    ペインクリニック   44 ( 2 )   184 - 189   2023.2

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • A case of iliopsoas hematoma after misplacement of vascular access catheter in the ascending lumbar vein Reviewed

    Furusawa Takahiro, Yano Takeshi, Kashino Rina, Yoshikai Mizuho, Koshida Tomohiro, Yonaha Tetsu, Taniguchi Masahiko, Tsuneyoshi Isao

    Journal of the Japanese Society of Intensive Care Medicine   30 ( 1 )   23 - 24   2023.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society of Intensive Care Medicine  

    DOI: 10.3918/jsicm.30_23

    CiNii Research

  • Effect of cryoprecipitate on an increase in fibrinogen level in patients with excessive intraoperative blood loss: a single-center retrospective study Reviewed

    Kouroki S., Maruta T., Tsuneyoshi I.

    JA Clinical Reports   8 ( 1 )   2022.12

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:JA Clinical Reports  

    Background: Cryoprecipitate, which contains fibrinogen and factor VIII in large quantities, is concentrated from fresh frozen plasma, and it has hemostatic effects in severe bleeding. We retrospectively examined the effects of cryoprecipitate on the increase in fibrinogen levels in patients with excessive intraoperative blood loss. Methods: Ninety-seven patients who were administered cryoprecipitate during surgery between June 2014 and May 2019 were enrolled in our study and categorized according to the volume of intraoperative blood loss as follows: group A, 2000–5000 mL; group B, 5000–10,000 mL; group C, > 10,000 mL. Data were extracted from electronic medical records and electronic anesthesia records. The primary endpoint was an increase in the fibrinogen level after the administration of cryoprecipitate. Results: Nine patients with no fibrinogen data and four patients with a bleeding volume of less than 2000 mL were excluded; thus, 84 patients (A: n = 36, B: n = 37, C: n = 11) were evaluated. The mean intraoperative blood loss (mL) in groups A, B, and C were 3348 ± 791, 6688 ± 1225, and 14,281 ± 5142, respectively. The fibrinogen levels (mg/dL) before cryoprecipitate administration in groups A, B, and C were 189 ± 94, 113 ± 42, and 83 ± 29, respectively (p < 0.05 among the groups). The increase in fibrinogen level (mg/dL) after cryoprecipitate administration in group C was significantly greater than that in group A (84 ± 34 versus 50 ± 36, p < 0.01). Conclusions: The results of this study indicate that the effect of cryoprecipitate on the increase in fibrinogen level was most apparent in patients with excessive intraoperative blood loss ≥ 10,000 mL. In addition, most patients with intraoperative blood loss ≥ 5000 mL had fibrinogen levels < 150 mg/dL which improved to ≥ 150 mg/dL after cryoprecipitate administration in approximately 70% of patients. Therefore, cryoprecipitate administration should be considered for patients with hypofibrinogenemia (≤ 150 mg/dL) experiencing severe bleeding (e.g., ≥ 5000 mL) and rapid administration of cryoprecipitate is necessary to maximize the hemostatic effect, especially when the bleeding volume exceeds 10,000 ml.

    DOI: 10.1186/s40981-022-00516-5

    Scopus

  • 医療安全を支えるNon-Technical Skills「大学病院における多職種ノンテクニカルスキルの実践」安全管理確保のための質改善向上の取り組み Reviewed

    綾部貴典,奥村 学,神田久美子,中村小夜子,小田浩美,山本亜矢,甲斐由紀子,恒吉勇男

    日本外科学会雑誌   123 ( 6 )   633 - 635   2022.11

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Epidural Anesthesia and Continuous Epidural Analgesia in a Pediatric Patient With Pelizaeus-Merzbacher Disease: A Case Report. Reviewed

    Toyoaki Maruta, Yumi Watanabe, Yukiko Nagata, Rina Kashino, Isao Tsuneyoshi

    Cureus   14 ( 10 )   2022.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.7759/cureus.29983.

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Books 【 display / non-display

  • 臨床麻酔科学書

    荒川英樹,恒吉勇男( Role: Joint author ,  術後早期離床・リハビリテーション)

    中山書店  2022.7 

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    Responsible for pages:712-714   Language:Japanese Book type:Scholarly book

  • 臨床麻酔科学書

    山下幸貴,恒吉勇男( Role: Joint author ,  術後せん妄対策)

    中山書店  2022.7 

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    Responsible for pages:710-711   Language:Japanese Book type:Scholarly book

  • 臨床麻酔科学書

    恒吉勇男( Role: Joint author ,  術後循環管理)

    中山書店  2022.7 

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    Responsible for pages:708-709   Language:Japanese Book type:Scholarly book

  • 臨床麻酔科学書

    恒吉勇男( Role: Joint author ,  術後呼吸管理)

    中山書店  2022.7 

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    Responsible for pages:706-707   Language:Japanese Book type:Scholarly book

  • 高齢者麻酔のポイント50

    恒吉勇男( Role: Joint author ,  高齢者の術前検査の評価について注意点を教えて下さい.)

    克誠堂出版  2021.6 

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    Language:Japanese Book type:Textbook, survey, introduction

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MISC 【 display / non-display

  • 挿管チューブ固定テープによる皮膚損傷について(Q&A). Invited Reviewed

    村瀬玲子,山田高成、森崎 浩、恒吉勇男

    臨床麻酔   43 ( 6 )   881 - 884   2019.6

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 各歳人口構成による年間手術件数の解析.

    指宿昌一郎,恒吉勇男

    日本手術医学会誌   38 ( 1 )   40 - 43   2017.2

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • デスフルランの上手な使い方 各科手術での使用:高齢者手術―高齢者への応用の長所・短所―.

    矢野武志,恒吉勇男

    日本臨床麻酔学会誌   36 ( 4 )   479 - 483   2016.7

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • デスフルランの上手な使い方 各科手術での使用:頭頚部外科手術・眼科手術―眼内圧,咽頭喉頭筋群(SAS)への影響―

    森 信一郎,恒吉勇男

    日本臨床麻酔学会誌   36 ( 4 )   460 - 463   2016.7

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 移動体からの生体情報転送の試み online storageを用いたpaperChart活用.

    森 信一郎,指宿昌一郎,恒吉勇男

    麻酔・集中治療とテクノロジー 2015   40 - 44   2016.5

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

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Presentations 【 display / non-display

  • 難治性後頭部痛に対して,大後頭神経へのパルス高周波法が有効であった一症例.

    吉海瑞穂,日髙康太郎,渡部由美,山賀昌治,恒吉勇男

    日本ペインクリニック学会第2回九州支部学術集会 

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    Event date: 2022.2.28 - 2022.3.13

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 帯状疱疹後神経痛モデルラットにおける高周波パルス療法の作用機序の検討.

    日髙康太郎,丸田豊明,越田智広,興梠聡志,白阪哲朗,恒吉勇男

    第43回日本疼痛学会 

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    Event date: 2021.12.10 - 2021.12.11

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 人工呼吸器HAMILTON-G5に内蔵された高流量酸素投与機能の使用経験.

    村社瑞穂,長嶺佳弘,矢野武志,谷口正彦,恒吉勇男

    日本臨床麻酔学会第41回大会 

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    Event date: 2021.11.5 - 2021.11.7

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 腹臥位療法後にICU-acquired weaknessを発症した重症COVID-19の1症例.

    古澤高廣,矢野武志,村社瑞穂,深尾麻由,與那覇 哲,山下幸貴,谷口正彦,恒吉勇男

    日本臨床麻酔学会第41回大会 

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    Event date: 2021.11.5 - 2021.11.7

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 年齢のロクロニウムの作用発現時間と作用持続時間に及ぼす影響.

    押川 隆,白阪哲朗,恒吉勇男

    日本臨床麻酔学会第41回大会 

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    Event date: 2021.11.5 - 2021.11.7

    Language:Japanese   Presentation type:Oral presentation (general)  

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Grant-in-Aid for Scientific Research 【 display / non-display

  • ヒト臍帯動脈におけるmyogenic response の検討

    2016.04 - 2019.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

  • ヒト血管の反応性;正常反応から病態変化に関する研究

    2012.04 - 2015.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

    ヒト血管の反応性;正常反応から病態変化に関する研究

  • 麻酔ならびにショック時の血管反応性に関する研究

    2009.04 - 2012.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

    麻酔ならびにショック時の血管反応性に関する研究

  • ヒト血管平滑筋を用いた敗血症ならびに人工心肺時における血管反応性に関する研究

    2005.04 - 2008.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

    ショック患者の血管および平滑筋細胞レベルでの内部環境の変化を理解し,その背後にある複雑な病態ネットワークを解明,解析する

  • 敗血症性ショックならびに多臓器不全時における血管反応性に関する研究

    2002.04 - 2004.03

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

    ショック時における1)血管弛緩,収縮因子の発現状況および各因子間の相互作用,2)内因性ホルモンの分泌と循環動態との関連性,3)血管反応性低下のメカニズムを分析・解析し,血管反応性を回復させうる新しい治療法の研究・開発を勤めることを目的とした研究

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