KITAHARA Go

写真a

Affiliation

Faculty of Agriculture Department of Veterinary Science Animal clinical breeding study course

Title

Associate Professor

External Link

Degree 【 display / non-display

  • 博士(獣医学) ( 2012.9   山口大学 )

  • 学士(獣医学) ( 2002.3   鹿児島大学 )

Research Areas 【 display / non-display

  • Life Science / Veterinary medical science

 

Papers 【 display / non-display

  • Immunohistochemical and Morphological Features of Bovine Granulosa Cell Tumours in Relation to Growth Pattern and Folliculogenesis Reviewed

    Teh A.P.P., Kitahara G., Izzati U.Z., Mori K., Fuke N., Hirai T., Yamaguchi R.

    Journal of Comparative Pathology   187   40 - 51   2021.8

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Journal of Comparative Pathology  

    Granulosa cell tumours (GCTs) are the most common type of bovine ovarian neoplasm. We describe the morphological and immunohistochemical features of GCTs (n = 26) and a thecoma (n = 1) using antibodies to cytokeratin AE1/AE3, vimentin, desmin, nectin-4, anti-Müllerian hormone (AMH), inhibin α, c-erbB-2 oncoprotein and proliferating cell nuclear antigen. The results indicate that, based on the expression similarity of AE1/AE3 and inhibin α, the macrofollicular growth pattern of GCTs derives from highly differentiated granulosa cells (GCs), the Graafian follicle or early atretic follicle. The trabecular growth pattern of GCTs is inferred to be derived from GCs of the atretic follicle in mature animals. AMH is a useful marker for diagnosing bovine sex cord-stromal tumours because it was expressed in all GCT cases and in the single case of thecoma.

    DOI: 10.1016/j.jcpa.2021.06.008

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  • 黒毛和種牛の正常産と難産における母牛骨盤と産子サイズ比の比較

    前田 崇史, 北原 豪, 大澤 健司

    畜産技術   2021

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Association of intrauterine presence of <i>Lactobacillus</i> spp. with inflammation and pathogenic bacteria in the uterus in postpartum dairy cows Reviewed

    WU Xinyue, KITAHARA Go, SUENAGA Tetsuya, NARAMOTO Kanami, SEKIGUCHI Satoshi, GOTO Yoshitaka, OSAWA Takeshi

    Journal of Reproduction and Development   67 ( 6 )   340 - 344   2021

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Society for Reproduction and Development  

    <p> The aim of this study was to clarify the influence of <i>Lactobacillus</i> spp. on the degree of endometrial inflammation in the postpartum period and the relationship between <i>Lactobacillus</i> spp. and pathogenic bacteria in the endometrium of postpartum dairy cows. Endometrial samples were collected from 41 Holstein-Friesian cows at 4 and 8 weeks postpartum using cytobrushes for polymorphonuclear neutrophil (PMN) count and bacterial culture to isolate <i>Lactobacillus</i> spp., <i>Escherichia coli,</i> and <i>Trueperella pyogenes</i>. The 4-week samples were divided into four groups (E+L+), (E+L−), (E−L+), (E−L−) according to whether endometritis was diagnosed (E+) and <i>Lactobacillus</i> spp. was isolated (L+)<i>.</i> The diagnostic criterion for cytological endometritis was > 18% PMN. The average PMN% in the E+L+ group was lower than that in the E+L-group (P < 0.05) at 8 weeks postpartum. There were no significant correlations between the number of colonies of <i>Lactobacillus</i> spp. and <i>E. coli</i> or between that of <i>Lactobacillus</i> spp. and <i>T. pyogenes</i>. <i>Lactobacillus</i> spp. could reduce PMN% in dairy cows with endometritis during the puerperal period. In conclusion, the intrauterine presence of <i>Lactobacillus</i> spp. may have a positive effect on uterine involution in postpartum dairy cows.</p>

    DOI: 10.1262/JRD.2021-023

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    CiNii Research

  • Impact of summer heat stress on the thermal environment of bovine female genital tract Reviewed

    El-Sheikh Ali H., Tamura Y., Sameshima H., Kitahara G.

    Tropical Animal Health and Production   52 ( 6 )   3449 - 3455   2020.11

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Tropical Animal Health and Production  

    Summer heat stress (HS) is associated with a reduction in conception rate, increase in services per conception, and early embryonic death. However, the impact of summer HS on the thermal environment of different regions of the bovine female genital tract remains unknown. This study aimed to elucidate the effect of summer HS on the thermal environment of different regions of the genital tract in the cow. Three non-pregnant Japanese Black cows were investigated using a specially designed digital thermometer to record the temperatures of the rectum (RT), vagina (VT), cervix (CT), uterine body (UBT), and uterine horns (UHT) on days 0, 1, 2, 3, and 8 of the estrous cycle (day 0 = heat) in February (winter), May (spring), and August (summer). During the experiment, the temperature humidity index (THI) was recorded. THI during summer was higher (P ˂ 0.001) than in winter and spring (78.45 ± 0.32 vs. 60.26 ± 1.20 and 68.51 ± 0.80, respectively) and was higher than the alert THI indicating HS (i.e., THI > 73). Consequently, the VT, CT, UBT, and UHT were elevated during summer HS (P < 0.05) in comparison to winter and spring. THI was positively correlated (P < 0.01) with RT, VT, CT, UBT, and UHT. Linear regression revealed that VT, CT, UBT, and UHT increased by 0.05 °C per unit of THI. VT was more highly correlated than RT with THI and with the temperature of other regions of genital tract. HS induced increases in the temperatures of different regions of the female genital tract. The relationship between THI and VT could be incorporated into a mathematical model to predict the thermal load of HS on different regions of the female genital tract.

    DOI: 10.1007/s11250-020-02378-4

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  • Intrauterine infusion of povidone-iodine: Its effect on the endometrium and subsequent fertility in postpartum dairy cows Reviewed

    Yoshida R., Kitahara G., Osawa T.

    Journal of Veterinary Medical Science   82 ( 7 )   926 - 934   2020.7

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Journal of Veterinary Medical Science  

    This study aimed to describe the duration of inflammation after intrauterine infusion of polyvinylpyrrolidone-iodine (povidone-iodine, PVP-I), determine the effect of PVP-I infusion on the subsequent fertility, and evaluate the histopathology of the endometrium in dairy cows. In Experiment 1, 120 lactating clinically healthy Holstein-Friesian cows at 5 weeks postpartum (W5) were equally divided into three groups: intrauterine infusion of 2% PVP-I (PVP), saline (SAL), and no treatment (NTX). Endometrial cytology was performed daily from D0 (W5) to D7 to determine the percentage of polymorphonuclear cells (PMN%) in 44 of the 120 cows. All cows received timed artificial insemination at D17. In Experiment 2, 25 cows were randomly classified into sacrifice at 24 hr or 48 hr after 2% PVP-I infusion (PVP24 and PVP48), and 24, 48, 72, or 96 hr after SAL infusion (SAL24; SAL48; SAL72; SAL96), or no treatment (NTX). Histopathology was performed on the uterus of each cow. In Experiment 1, PMN% was greater in PVP (P<0.05) than in SAL and NTX, on D1, but decreased to a level similar to that of the other groups by D2. Conception rate was higher (P<0.05) in PVP cows compared to SAL and NTX cows. In Experiment 2, stratified columnar epithelium in the uterus disappeared in PVP24 and SAL24. The epithelium was regenerated in PVP48, SAL72, and SAL96, but not in SAL48. In conclusion, the results of the study suggest that PVP-I induces transient uterine inflammation, promotes regeneration of endometrial epithelial cells and improves fertility.

    DOI: 10.1292/jvms.20-0165

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Books 【 display / non-display

  • 大・中・小動物実験プロトコール

    宮崎大学動物実験プロトコール編集委員会( Role: Joint author)

    宮日文化情報センター  2016.3 

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    Language:Japanese Book type:Scholarly book

  • 畜産ハンドブック 2.6 性の役割と性分化

    北原 豪( Role: Sole author)

    (株)講談社サイエンティフィク  2014.7 

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    Language:Japanese Book type:Dictionary, encyclopedia

  • 子牛の医学 第7章泌尿・生殖器疾患 第4節 生殖器の異常

    北原 豪( Role: Supervisor (editorial))

    緑書房  2014.3 

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    Language:Japanese Book type:Scholarly book

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  • 海外テクニカルニュース:乳牛における受胎性や発情発現における人工授精時の性腺刺激ホルモン放出ホルモンの投与効果 Invited

    北原 豪

    臨床獣医   40 ( 3 )   62 - 63   2022.3

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:緑書房  

  • 海外テクニカルニュース:乳牛における妊娠期の高温多湿環境や泌乳状況で産子の卵巣予備能が影響を受ける Invited

    北原 豪

    臨床獣医   40 ( 2 )   68 - 69   2022.2

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:緑書房  

  • 海外テクニカルニュース:肉牛における繁殖と長命を強化するための未経産牛に対するマネジメントの影響 Invited

    北原 豪

    臨床獣医   40 ( 1 )   64 - 65   2022.1

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:緑書房  

  • 海外テクニカルニュース:牛における胚移植時と胚移植後のフルニキシンメグルミン投与による妊娠率への影響 Invited

    北原 豪

    臨床獣医   39 ( 12 )   64 - 65   2021.12

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:緑書房  

  • 海外テクニカルニュース:Trueperella pyogenesによる臨床型子宮内膜炎に罹患した乳牛では,繁殖性や乳量が低下する Invited

    北原 豪

    臨床獣医   39 ( 11 )   82 - 83   2021.11

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:緑書房  

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Presentations 【 display / non-display

  • Effect of 5-aminolevulinic acid on developmental competence of oocytes from bovine ovaries collected in different season. International conference

    Omnia Elgendy, Go Kitahara, Shin Taniguchi, Takeshi Osawa

    The 3rd Joint Symposium between FACTRC in SNU and CADIC in UoM  (Web)  日本繁殖生物学会

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    Event date: 2022.3.23

    Language:English   Presentation type:Oral presentation (general)  

    Venue:Web  

  • 暑熱環境下での胚移植を成功させるために~健全な胚生産のための新たなアプローチ

    北原 豪

    第5回日本胚移植技術研究会大会  (Web)  2022.2.8  日本繁殖生物学会

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    Event date: 2022.2.8 - 2022.2.9

    Language:Japanese   Presentation type:Symposium, workshop panel (nominated)  

    Venue:Web  

  • 黒毛和種経産牛の正常分娩に伴う子宮頸管熟化におけるコラーゲン組成に関連した変化

    山之口 瑛悟,北原 豪,小林 郁雄,邉見 広一郎,菱川 善隆,Narantsog Choijookhuu,山口 良二,大澤 健司

    第114回日本繁殖生物学会大会  (Web)  日本繁殖生物学会

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    Event date: 2021.9.21 - 2021.9.24

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:Web  

  • 御崎馬における繁殖障害の原因病原体の保菌状況と糞中性ステロイドホルモンによる受胎性評価との関連

    砂山 大地,北原 豪,小林 郁雄,紙野 瑞希,楠田 哲士,上村 涼子,平井 卓哉,後藤 義孝,大澤 健司

    第164回日本獣医学会学術集会  (Web)  日本獣医学会

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    Event date: 2021.9.7 - 2021.9.13

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:Web  

  • 低産次で不受胎を繰り返した黒毛和種繁殖雌牛におけるその後の不受胎率の追跡調査

    谷村幹太、上松瑞穂、北原豪、大澤健司、佐々木羊介

    日本畜産学会第128回大会  (Web)  日本畜産学会

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    Event date: 2021.3.27 - 2021.3.30

    Language:Japanese   Presentation type:Poster presentation  

    Venue:Web  

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Awards 【 display / non-display

  • English Presentation Award

    2019.3  

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 平成30年度日本獣医師会獣医学術学会年次大会学会長賞

    2019.2   日本産業動物獣医学会  

    鳥巣至道、保坂悠歩、金子泰之、北原豪、日髙勇一、桐野有美、水谷真也、山本集士

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 平成30年度獣医学術九州地区学会産業動物獣医学会地区学会長賞

    2018.10   日本産業動物獣医学会九州地区学会  

    保坂悠歩、鳥巣至道、金子泰之、北原豪、佐藤裕之、水谷真也、山本集士、Benedict Huai Ern ONG、水谷祐子、桐野有美、日髙勇一、浅沼武敏、永延清和

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 平成29年家畜診療賞

    2018.2   全国農業共済協会  

    佐藤知広,北原 豪,大澤健司

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    Award type:Honored in official journal of a scientific society, scientific journal  Country:Japan

  • 平成29年度農学部表彰論文

    2017.12   宮崎大学農学部  

    El-Sheikh Ali, H., Kitahara, G., Takahashi, T., Mido, S., Sadawy, M., Kobayashi, I., Hemmi, K., Osawa, T.

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    Country:Japan

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Grant-in-Aid for Scientific Research 【 display / non-display

  • 牛の子宮頚管熟化機構の解明と分娩後早期の一過性炎症惹起による子宮疾患制御

    Grant number:21H02362  2021.04 - 2024.03

    科学研究費補助金  基盤研究(B)

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    Authorship:Coinvestigator(s) 

  • ウシ潜在性子宮内膜炎の病態解明と治療・予防ストラテジーの確立

    2016.04 - 2020.03

    科学研究費補助金  基盤研究(B)

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    Authorship:Coinvestigator(s) 

  • GhrelinとNeuromedin U/Sの自律神経様作用の解明と応用への研究

    2016.04 - 2020.03

    科学研究費補助金  基盤研究(B)

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    Authorship:Coinvestigator(s) 

  • バイオマーカーによる家畜の卵巣機能の質および量的評価法の確立

    2016.04 - 2019.03

    科学研究費補助金  若手研究(B)

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    Authorship:Principal investigator 

  • 抗ミューラー管ホルモンを用いた新しい繁殖管理技術の開発

    2013.04 - 2016.03

    科学研究費補助金  若手研究(B)

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    Authorship:Principal investigator 

    これまで国内外で調べられていない雌ウシの春機発動時期と周産期におけるAMHの動態を明らかにし、初産分娩月齢や分娩後の空胎日数などの繁殖効率の指標となる繁殖成績との関係を解析して、AMHをバイオマーカーとした生時より備わっている繁殖能力や周産期における非生産時の繁殖機能を評価する新しい繁殖管理技術の開発に挑む。

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