研究者詳細 - 田島　卓也

Clinical and Radiographic Outcomes of Double-Bundle Anterior Cruciate Ligament Reconstruction for Asian Patients with Bone-Patellar Tendon-Bone and Gracilis Tendon Grafts: A Matched-Control Comparison. 査読あり

Tajima T, Yamaguchi N, Morita Y, Nagasawa M, Ota T, Nakamura Y, Yokoe T, Chosa E

The journal of knee surgery 2020年5月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1055/s-0040-1710376

Early weight-bearing after anterior cruciate ligament reconstruction with hamstring grafts induce femoral bone tunnel enlargement: A prospective clinical and radiographic study 査読あり

Remnant-preserving, selective single-bundle augmentation of the anterior cruciate ligament using a bone–patellar tendon–bone autograft: 査読あり

Takuya Tajima , Etsuo Chosa, Nami Yamaguchi, Noboru Taniguchi, Yasuyuki Ishida

The Knee 32 554 - 558 2016年6月

記述言語：英語掲載種別：研究論文（学術雑誌）

Comprehensive safety management and assessment at rugby football competitions 査読あり

Tajima T, Chosa E, Kawahara K, Nakamura Y, Yoshikawa D, Yamaguchi N, Kashiwagi T

International Journal of Sports Medicine 35 ( 12 ) 1012 - 1016 2014年11月

記述言語：英語掲載種別：研究論文（学術雑誌）

Hemoglobin stimulates the expression of matrix metalloprotenases, MMP-2 and MMP-9 by synovial cells: a possible cause of joint damage after intra-articular hemorrhage. 査読あり

Takuya Tajima, Etsuo Yoshida, Atsushi Yamashita, Sayuri Ohmura, Yasushi Tomitaka, Masahiko Sugiki, Yujiro Asada, Masugi Maruyama

Journal of Orthopaedic Research 23 891 - 898 2005年4月

記述言語：英語掲載種別：研究論文（学術雑誌）

Head Injury Assessment in the Elite Level Rugby Union in Japan: Review of 3 Seasons. 査読あり

Tajima T*, Ota O, Nagayama M, Takahashi M, Yamada M, Ishiyama N, Yoshida I, Takemura M, Hara K, Akama T, Mitsumori N, Higashihara J, Toyama Y, Furuya M, Chosa E, Nakamura A.

International Journal of Sports Medicine 2022年6月

担当区分：筆頭著者記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1055/a-1810-6509.

Tajima T., Yamaguchi N., Nagasawa M., Morita Y., Nakamura Y., Chosa E.

BMC Musculoskeletal Disorders 20 ( 1 ) 274 2019年6月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：BMC Musculoskeletal Disorders

© 2019 The Author(s). Background: Bone tunnel enlargement following primary anterior cruciate ligament (ACL) reconstruction with soft tissue graft might be a severe disadvantage for revision surgery. The postoperative rehabilitation protocol including the non-weight-bearing periods were different depending on the surgeon or institute. To determine the relationship between femoral bone tunnel enlargement and the postoperative non-weight-bearing period after double-bundle ACL reconstruction with hamstring grafts. Methods: Forty-two patients who underwent primary double-bundle ACL reconstruction with hamstring grafts were divided into two postoperative non-weight-bearing protocol groups: 1-week non-weight-bearing postoperatively (group A, n = 19); and 2-week non-weight-bearing (group B, n = 18). Five cases were excluded due to additional knee injury, pregnancy, and lost to follow-up. Bone tunnel enlargement was evaluated by computed digital radiographs (anteroposterior (A-P) and lateral views) taken on the first postoperative day and at 12 months. Each tunnel diameter was shown as a percentage to the maximum joint width of the proximal tibia in the A-P view, or a percentage of the maximum diameter of the patella in the lateral view. To determine the incidence of tunnel enlargement, percentage diameter changes of more than 10% were defined as an enlarged tunnel. The magnitude of tunnel enlargement and the standard clinical evaluation were also evaluated. Results: There were no significant differences between groups in the incidences of anteromedial and posterolateral bone tunnel enlargement, both in the A-P and lateral views (2 × 2 Chi-squared test). The magnitude of femoral posterolateral bone tunnel enlargement was significantly greater in group A in the A-P view (p = 0.01) and lateral view (p = 0.03) (Mann Whitney U-test). Twelve months after surgery, the Lysholm score and Tegner activity level scale were not significantly different between the groups. Conclusions: This prospective, clinical and radiographical study showed that early weight-bearing protocol after double-bundle ACL reconstruction with hamstring grafts might have the potential risk of significant postoperative femoral bone tunnel enlargement of the posterolateral bundle. There was no significant difference in clinical outcomes by postoperative non-weight-bearing period. To reduce and prevent the femoral bone tunnel enlargement, the comprehensive management could be considered and required to establish the suitable early stage rehabilitation protocol after surgery. Trial registration: Trial registration number; UMIN000036212. Scientific title: Prospective comparisons of femoral tunnel enlargement with two different postoperative non weight bearing periods after double-bundle anterior cruciate ligament reconstruction with hamstring grafts. Registered date: 15 Mar 2019 (retrospectively registered).

DOI： 10.1186/s12891-019-2653-6

Hemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells; a possible cause of articular cartilage damage after intra-articular hemorrhage 招待あり査読あり

Tajima T., Sekimoto T., Yamaguchi N., Taniguchi N., Kurogi S., Maruyama M., Chosa E.

BMC Musculoskeletal Disorders 18 ( 1 ) 449 - 457 2017年11月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1186/s12891-017-1815-7

Effect of genu recurvatum on the anterior cruciate ligament-deficient knee during gait 査読あり

Katsuhiro Kawahara,Tomohisa Sekimoto,Shinji Watanabe,Keitaro Yamamoto,Takuya Tajima,Nami Yamaguchi, Etsuo Chosa

Knee Surgery, Sports Traumatology, Arthroscopy 20 ( 8 ) 1479 - 1487 2012年8月

記述言語：英語掲載種別：研究論文（学術雑誌）

Anterior cruciate ligament reconstruction in a patient with Athetoid cerebral palsy 査読あり

Takuya Tajima, Etsuo Chosa, Keitarou Yamamoto, Nami Yamaguchi, Shinji Watanabe

Sports Medicine, Arthroscopy,Rehabilitation, Therapy &Technology 36 ( 4 ) 2012年4月

記述言語：英語掲載種別：研究論文（学術雑誌）

Orthopaedic medical examination for young amateur athletes: a repeated cross-sectional study from 2014 to 2018. 査読あり

Yokoe T, Tajima T, Yamaguchi N, Nagasawa M, Ota T, Morita Y, Chosa E

BMJ open 11 ( 1 ) e042188 2021年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：BMJ Open

Objectives Medical examinations for adult elite athletes are performed all over the world, however, no studies in the relevant English literature have reported on orthopaedic medical examinations for young amateur athletes. The purpose of this study was to report the results of orthopaedic medical examinations of the spine and lower extremities in young amateur athletes. Methods This repeated cross-sectional study from 2014 to 2018 included a total of 323 young amateur athletes (age, 12-18 years) who were active in one of the following four sports: boxing, canoeing, weightlifting and track and field. The orthopaedic medical examination consisted of six assessments (physical examinations, the generalised joint laxity, muscle and joint tightness, static alignment and muscle volume of the lower extremities and the medial longitudinal arch of the foot). Questions regarding pain in the spine and lower extremities were also performed. Results Among 323 young amateur athletes, 17 (5.3%) had received orthopaedic treatment at the time of the medical examination, with spondylolysis being the most common cause (29.4%, 5/17). Among 306 young athletes who had not received orthopaedic treatment, 61 (19.9%) had at least one positive finding in physical examinations or had pain in the spine or lower extremities. Anterior drawer test of the ankle and Kemp test for the spine accounted for 34% and 28% of positive findings, respectively. Low back pain and knee pain accounted for 58% and 16% of pain, respectively. Conclusions The present study showed that approximately one-fifth of young amateur athletes who had not received orthopaedic treatment had pain in the spine and lower extremities and positive findings in physical examinations that may require orthopaedic treatments. In addition to the early detection of injuries, orthopaedic medical examinations for young amateur athletes provide an opportunity to educate such athletes.

DOI： 10.1136/bmjopen-2020-042188

Comparison of symptomatic spondylolysis in young soccer and baseball players 査読あり

Yokoe T., Tajima T., Sugimura H., Kubo S., Nozaki S., Yamaguchi N., Morita Y., Chosa E.

Journal of Orthopaedic Surgery and Research 15 ( 1 ) 378 2020年9月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Orthopaedic Surgery and Research

© 2020 The Author(s). Background: Spondylolysis is the main cause of low back pain (LBP) in young athletes. There are few studies analyzing the difference of spondylolysis among young athletes with different sports activities. The purpose of this study was to compare the clinical factors and distribution of the lesions of spondylolysis on magnetic resonance imaging (MRI) scans in young soccer and baseball players with symptomatic spondylolysis. Methods: The medical records of 267 young athletes aged 7 to 18 years old who underwent MRI to evaluate the cause of LBP between 2017 and 2020 were retrospectively reviewed to identify patients with spondylolysis. Of the young athletes with symptomatic spondylolysis, clinical factors and MRI findings in soccer and baseball players were retrospectively evaluated. The clinical factors were age, sex, interval from onset of LBP to MRI, and side of the dominant leg in the sports field. MRI findings included number, lumbar level, and side of the lesions. Results: A total of 33 soccer players (mean age, 15.4 ± 1.4 years) and 49 baseball players (mean age, 15.4 ± 1.6 years) with symptomatic spondylolysis were enrolled. All patients were male. No significant differences were noted in age and the interval from onset of LBP to MRI between the groups. Soccer players had greater numbers of multiple (p < 0.001) and bilateral (p < 0.001) lesions than baseball players. The dominant side of the hand for pitching or batting was correlated with the contralateral-side lesions in baseball players (p = 0.001). Conclusions: The distribution of the lesions of spondylolysis differed in young soccer and baseball players. Pitching or batting with the dominant-side hand would be associated with contralateral-side lesions in baseball players. Sports-specific movements and the side of the dominant leg should be considered when treating young athletes with symptomatic spondylolysis.

DOI： 10.1186/s13018-020-01910-4

Googling musculoskeletal-related pain and ranking of medical associations' patient information pages: Google ads keyword planner analysis 査読あり

ラグビー選手における頚椎退行変性の予防-頚部体幹コアトレーニング導入の効果- 査読あり

田島卓也、帖佐悦男、河原勝博、山口奈美、中村嘉宏

日本整形外科スポーツ医学会雑誌 34 ( 1 ) 80 - 84 2014年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Yamaguchi Y., Lee D., Nagai T., Funamoto T., Tajima T., Chosa E.

Journal of Medical Internet Research 22 ( 8 ) e18684 2020年8月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Medical Internet Research

© 2020 Journal of Medical Internet Research. All rights reserved. Background: Most people currently use the internet to obtain information about many subjects, including health information. Thus, medical associations need to provide accurate medical information websites. Although medical associations have their own patient education pages, it is not clear if these websites actually show up in search results. Objective: The aim of this study was to evaluate how well medical associations function as online information providers by searching for information about musculoskeletal-related pain online and determining the ranking of the websites of medical associations. Methods: We conducted a Google search for frequently searched keywords. Keywords were extracted using Google Ads Keyword Planner associated with "pain" relevant to the musculoskeletal system from June 2016 to December 2019. The top 20 search queries were extracted and searched using the Google search engine in Japan and the United States. Results: The number of suggested queries for "pain" provided by Google Ads Keyword Planner was 930 in the United States and 2400 in Japan. Among the top 20 musculoskeletal-related pain queries chosen, the probability that the medical associations' websites would appear in the top 10 results was 30% in the United States and 45% in Japan. In five queries each, the associations' websites did not appear among the top 100 results. No significant difference was found in the rank of the associations' website search results (P=.28). Conclusions: To provide accurate medical information to patients, it is essential to undertake effective measures for search engine optimization. For orthopedic associations, it is necessary that their websites should appear among the top search results.

DOI： 10.2196/18684

Surgical Wound Complications after Knee Cruciate Ligament Reconstruction in Patients with Atopic Dermatitis. 査読あり

Yokoe T, Tajima T, Yamaguchi N, Morita Y, Chosa E

The journal of knee surgery 34 ( 11 ) 1237 - 1242 2020年2月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Knee Surgery

Atopic dermatitis (AD), sometimes referred to as eczema, is a common skin disease, and skin barrier dysfunction and immunological disorders are well recognized. However, surgical wound complications after orthopaedic surgery in patients with AD have not been described. This study aimed to report four patients with AD who developed foreign body reactions to FiberWire sutures with or without surgical wound infection (SSI) after knee cruciate ligament reconstruction (CLR). The mean age was 19.8 (range, 16-25) years, and patients 1 and 3 underwent reconstructions of the posterior and anterior cruciate ligament, respectively. At a mean of 7.5 (range, 4-10) weeks postoperatively, discharge from the surgical wound at the tibial side of the fixed graft was identified. All patients were treated with continuous saline lavage and antibiotics; however, their wounds did not heal. Second-look arthroscopy and hardware removal were performed at a mean 12.2 (range, 9-15) months postoperatively. Proliferated granulation tissue surrounding the FiberWire was identified. Intraoperative wound cultures were negative in three of the four patients. Histological examination of the tissues adjacent to the FiberWire revealed a foreign body reaction. All wounds healed immediately after the second surgery. In addition to SSI, foreign body reactions are more likely to occur in patients with AD than in those without AD. Preoperative management of AD by dermatologists and consideration of appropriate suture materials are mandatory to reduce surgical wound complications after knee CLR in patients with AD.

DOI： 10.1055/s-0040-1702186

Elective one-stage all four-ligament reconstruction after open knee dislocation: A case report 査読あり

Yokoe T., Tajima T., Yamaguchi N., Chosa E.

Journal of Orthopaedic Science 27 ( 3 ) 743 - 749 2019年9月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Orthopaedic Science

DOI： 10.1016/j.jos.2019.08.012

Copy number loss in the region of the ASPN gene in patients with acetabular Dysplasia 査読あり

Sekimoto T., Ishii M., Emi M., Kurogi S., Funamoto T., Yonezawa Y., Tajima T., Sakamoto T., Hamada H., Chosa E.

Bone and Joint Research 6 ( 7 ) 439 - 445 2017年7月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Bone and Joint Research

© 2017 Cao et al. Objectives: We have previously investigated an association between the genome copy number variation (CNV) and acetabular dysplasia (AD). Hip osteoarthritis is associated with a genetic polymorphism in the aspartic acid repeat in the N-terminal region of the asporin (ASPN) gene; therefore, the present study aimed to investigate whether the CNV of ASPN is involved in the pathogenesis of AD. Methods: Acetabular coverage of all subjects was evaluated using radiological findings (Sharp angle, centre-edge (CE) angle, acetabular roof obliquity (ARO) angle, and minimum joint space width). Genomic DNA was extracted from peripheral blood leukocytes. Agilent's regiontargeted high-density oligonucleotide tiling microarray was used to analyse 64 female AD patients and 32 female control subjects. All statistical analyses were performed using EZR software (Fisher's exact probability test, Pearson's correlation test, and Student's t-test). Results: CNV analysis of the ASPN gene revealed a copy number loss in significantly more AD patients (9/64) than control subjects (0/32; p = 0.0212). This loss occurred within a 60 kb region on 9q22.31, which harbours the gene for ASPN. The mean radiological parameters of these AD patients were significantly worse than those of the other subjects (Sharp angle, p = 0.0056; CE angle, p = 0.0076; ARO angle, p = 0.0065), and all nine patients required operative therapy such as total hip arthroplasty or pelvic osteotomy. Moreover, six of these nine patients had a history of operative or conservative therapy for developmental dysplasia of the hip. Conclusions: Copy number loss within the region harbouring the ASPN gene on 9q22.31 is associated with severe AD. A copy number loss in the ASPN gene region may play a role in the aetiology of severe AD.

DOI： 10.1302/2046-3758.67.BJR-2016-0094.R1

Risk factors of failure results after double-bundle reconstruction with autogenous hamstring grafts for isolated posterior cruciate ligament rupture cases 査読あり

Screening for musculoskeletal problems in Japanese schoolchildren: a cross-sectional study nested in a cohort（共著）査読あり

N.Yamaguchi，E.Chosa，K.Yamamoto，K.Kawahara，H.Hamada，N.Taniguchi，T.Tajima，T.Funamoto，S.Kurogi，T.Ota，S.Nakamura

Public Health 139 189 - 197 2016年8月

記述言語：英語掲載種別：研究論文（学術雑誌）

ラグビー競技会における医療体制向上と重傷事故発生予防を目的とした安全度評価法の活用査読あり

田島卓也、帖佐悦男、山本惠太郎、中村嘉宏、山口奈美、柏木輝行

日本整形外科スポーツ医学会雑誌 32 ( 2 ) 35 - 40 2012年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

膝前十字靭帯再再建術症例の検討査読あり

田島卓也、山本惠太郎、石田康行、山口奈美、崎浜智美、帖佐悦男

JOSKAS雑誌 36 ( 4 ) 258 - 263 2011年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

九州地方にて開催されたラグビー競技会に対する安全度評価査読あり

田島卓也、帖佐悦男、山本惠太郎、河原勝博、中村嘉宏、吉川大輔、吉川教恵、柏木輝行、東原潤一郎

日本臨床スポーツ医学会雑誌 16 ( 3 ) 402- - 407 2008年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

ラグビー競技会に対する安全度評価について査読あり

田島卓也

日本臨床スポーツ医学会雑誌 12 ( 3 ) 478 - 482 2004年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

医学部ラグビー部員の頚部周囲筋力査読あり

田島卓也、田島直也、帖佐悦男、園田典生、山本惠太郎

日本臨床スポーツ医学会雑誌 490 - 494 2002年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

医学部ラグビー部員の頚椎変化：初心者における2年間での変化査読あり

田島卓也、田島直也、帖佐悦男、園田典生、樋口潤一

九州・山口スポーツ医科学研究会誌 12 86 - 91 2000年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

医学部ラグビー部員の頚椎変化(第一報）；初心者における1年間での変化査読あり

田島卓也、田島直也、帖佐悦男、園田典生、樋口潤一

日本整形外科スポーツ医学会雑誌 20 ( 1 ) 92 - 97 2000年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

医学部ラグビー部員の頚椎変化査読あり

田島卓也、田島直也、帖佐悦男、園田典生、樋口潤一

日本整形外科スポーツ医学会雑誌 19 ( 1 ) 63 - 68 1999年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Morita Y., Tajima T., Yamaguchi N., Yokoe T., Nagasawa M., Ota T., Ouchi K., Chosa E.

Scientific Reports 14 ( 1 ) 6192 2024年12月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Scientific Reports

Posterior tibial translation (PTT) after double-bundle posterior cruciate ligament (PCL) reconstruction has sometimes occurred. Purpose of this study is to identify the risk factors for postoperative PTT after double-bundle PCL reconstruction with a hamstring autograft. Comparing the results of bilateral gravity sag view (GSV) at 12 months after surgery, over 5-mm PTT was defined as ‘failure’ in this study. Of 26 isolated PCL reconstruction cases, over 5-mm PTT was seen in 7 cases (group F: 9.57 ± 1.28 mm), and 19 cases had less than 5 mm (group G: 2.84 ± 1.29 mm). Age, sex, body mass index (BMI), preoperative GSV, posterior slope angle of the tibia, anterolateral bundle (ALB) and posteromedial bundle (PMB) graft diameters, and tibial tunnel diameter were evaluated. The two groups were compared with the 2 × 2 chi-squared test, the Mann Whitney U-test, and Spearman’s rank correlation coefficient. Multivariate logistic regression analysis was also performed to determine the risk factor. Statistical significance was indicated as p < 0.01 for correlation with postoperative PTT, and as p < 0.05 for all other comparisons. Mean age (group G 31.8 ± 12.5 vs group F 34.9 ± 15.9 years), sex (male/female: 15/4 vs 3/4), BMI (25.6 ± 4.6 vs 24.9 ± 3.9 kg/m2), preoperative GSV (11.3 ± 2.2 vs 11.6 ± 2.9 mm), PMB diameter (5.37 ± 0.33 vs 5.36 ± 0.48 mm), and tibial tunnel diameter (9.32 ± 0.58 vs 9.29 ± 0.49 mm) showed no significant differences. ALB diameter was significantly greater in group G (7.0 ± 0.5 mm) than in group F (6.5 ± 0.29 mm; p = 0.022). There was also a significant difference in posterior tibial slope angle (group G 9.19 ± 1.94 vs group F 6.54 ± 1.45, p = 0.004). On Spearman rank correlation coefficient analysis, ALB diameter GSV (correlation coefficient: − 0.561, p = 0.003) and posterior tibial slope angle (correlation coefficient: − 0.533, p = 0.005) showed a significant correlation with postoperative PTT. Multivariate logistic regression analysis showed that ALB diameter (OR 19.028; 95% CI 1.082–334.6; p = 0.044) and posterior slope angle of tibia (OR 3.081; 95% CI 1.109–8.556; p = 0.031) were independently associated with postoperative PTT, respectively. In double-bundle PCL reconstruction with hamstring, smaller ALB graft diameter and lower (flatted) tibial slope angle were considered risk factors for postoperative PTT.

DOI： 10.1038/s41598-024-56953-y

特集外来でできる運動器疾患に対する最先端保存療法神経筋電気刺激療法(NMES)の筋萎縮予防･筋力増強効果査読あり

田島卓也, 帖佐悦男

関節外科　基礎と臨床 43 ( 14 ) 116 - 123 2024年10月

担当区分：筆頭著者,　責任著者掲載種別：研究論文（学術雑誌）出版者・発行元：メジカルビュー社

DOI： 10.18885/jjs.0000001945

特集大規模レジストリーによる整形外科リアルワールドエビデンス構築関節鏡およびスポーツ整形外科関連手術に対するレジストリー-JOSKAS eNOTEからJSOAレジストリーへ査読あり

田島卓也, 鈴木朱美

臨床整形外科 59 ( 7 ) 891 - 895 2024年7月

担当区分：筆頭著者,　責任著者掲載種別：研究論文（学術雑誌）出版者・発行元：株式会社医学書院

DOI： 10.11477/mf.1408203050

Differences in Retromalleolar Fibular Groove Morphology According to Level of Axial Computed Tomography Scans 査読あり

Takuji Yokoe, Takuya Tajima, Koki Ouchi, Nami Yamaguchi, Yudai Morita, and Etsuo Chosa

The Orthopaedic Journal of Sports Medicine 12 ( 3 ) 2024年3月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1177/23259671241237255

Risk of Skull Perforation with Halo Vest Skull Pins 査読あり

Hamanaka H., Tajima T., Kurogi S., Higa K., Nagai T., Takahashi T., Matsumoto T., Chosa E.

Spine Surgery and Related Research 8 ( 5 ) 480 - 484 2024年

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Spine Surgery and Related Research

Introduction: A halo vest is an immobilization device widely used to stabilize the cervical spine. Pain and infection at the skull pin insertion site are common complications, but skull perforation is rare, and most published studies are case reports. This study aimed to identify risk factors for skull perforation by comparing patients who did and did not develop perforation. Methods: Overall thickness and the thicknesses of the internal and external laminae of the skull at the skull pin insertion sites were measured on cranial computed tomography scans of 66 patients fitted with a halo vest. The results were compared between patients who did and did not develop perforation. Results: Four patients developed perforations. All patients with perforation were older women, and their external and internal laminae were significantly thinner than those of patients who did not develop perforation. Conclusions: The reported causes of skull pin perforation include infection around the pin, osteoporosis, and an enlarged frontal sinus. However, most patients with perforation in the present study were older women, and the cause was the thinning of the external and external laminae.

DOI： 10.22603/ssrr.2023-0261

3．ジャパンラグビーリーグワンにおける外傷・障害調査査読あり

田島卓也, 帖佐悦男, 中村明彦

日本臨床スポーツ医学会誌 32 ( 3 ) 342 - 344 2024年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：一般社団法人日本臨床スポーツ医学会

DOI： 10.57474/jjcsm.32.3_342

Age- and sex-related differences in upper-body joint and endpoint kinematics during a drinking task in healthy adults. 査読あり

Jun Nakatake, Hideki Arakawa, Takuya Tajima, Shigeaki Miyazaki, Etsuo Chosa

PeerJ 2023年12月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.7717/peerj.16571

Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway 査読あり

Nagai T., Sekimoto T., Kurogi S., Ohta T., Miyazaki S., Yamaguchi Y., Tajima T., Chosa E., Imasaka M., Yoshinobu K., Araki K., Araki M., Choijookhuu N., Sato K., Hishikawa Y., Funamoto T.

Scientific Reports 13 ( 1 ) 14639 2023年12月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Scientific Reports

Bone remodeling is an extraordinarily complex process involving a variety of factors, such as genetic, metabolic, and environmental components. Although genetic factors play a particularly important role, many have not been identified. In this study, we investigated the role of transmembrane 161a (Tmem161a) in bone structure and function using wild-type (WT) and Tmem161a-depleted (Tmem161aGT/GT) mice. Mice femurs were examined by histological, morphological, and bone strength analyses. Osteoblast differentiation and mineral deposition were examined in Tmem161a-overexpressed, -knockdown and -knockout MC3T3-e1 cells. In WT mice, Tmem161a was expressed in osteoblasts of femurs; however, it was depleted in Tmem161aGT/GT mice. Cortical bone mineral density, thickness, and bone strength were significantly increased in Tmem161aGT/GT mice femurs. In MC3T3-e1 cells, decreased expression of alkaline phosphatase (ALP) and Osterix were found in Tmem161a overexpression, and these findings were reversed in Tmem161a-knockdown or -knockout cells. Microarray and western blot analyses revealed upregulation of the P38 MAPK pathway in Tmem161a-knockout cells, which referred as stress-activated protein kinases. ALP and flow cytometry analyses revealed that Tmem161a-knockout cells were resistant to oxidative stress. In summary, Tmem161a is an important regulator of P38 MAPK signaling, and depletion of Tmem161a induces thicker and stronger bones in mice.

DOI： 10.1038/s41598-023-41837-4

Diagnostic utility of anteroposterior measurements of the median nerve on sagittal ultrasonographic images and their correlation with clinical findings in carpal tunnel syndrome. 査読あり

Okura T, Tajima T, Fukuda H, Matsuoka T, Chosa E

Journal of clinical ultrasound : JCU 2023年10月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1002/jcu.23584

Remnant-Preserved Single-Bundle Anterior Cruciate Ligament Augmentation in Multi-ligamentous Knee Reconstruction. 査読あり

Tajima T, Yamaguchi N, Morita Y, Yokoe T, Nagasawa M, Ota T, Kawagoe S, Nakamura Y, Chosa E.

J Knee Surg 36 ( 10 ) 1095 - 1101 2023年10月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1055/s-0042-1749603

第2趾DIP関節脱臼に対する観血的整復術後の早期スポーツ復帰の一例査読あり

川越亮, 田島卓也, 山口奈美, 大田智美, 長澤誠, 森田雄大, 横江琢示, 帖佐悦男

整形外科と災害外科 72 ( 3 ) 485 - 487 2023年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

【はじめに】観血的整復術を必要とした第2趾のDIP関節脱臼の1例を経験した．【症例】16歳男性．空手中に受傷．第2趾DIP関節脱臼で徒手整復を行ったが整復不能であったため，観血的整復術を行った．整復阻害因子は長趾屈筋腱であり，蹠側板の嵌頓は認めなかった．術後早期の競技復帰希望があったため母趾とのbuddy tapingを指示し復帰とした．術後6か月が経過し特に問題なく競技継続している．【考察】DIP関節脱臼の整復阻害因子は蹠側板や長趾屈筋腱の報告があり，本症例では長趾屈筋腱であった．また，術後のスポーツ復帰について，競技によっては症状次第で早期復帰が見込めると考えられた．

DOI： 10.5035/nishiseisai.72.485

Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway 査読あり

Takuya Nagai,Tomohisa Sekimoto,Syuji Kurogi,Tomomi Ohta, Shihoko Miyazaki,Yoichiro Yamaguchi,Takuya Tajima, Etsuo Chosa,Mai Imasaka,Kumiko Yoshinobu,Yoshitaka Hishikawa,Taro Funamoto

Scientific reports ( 14639 ) 2023年9月

記述言語：英語掲載種別：研究論文（大学，研究機関等紀要）

DOI： doi.org/10.1038/s41598-023-41837-4

私論学会で発表することの意義査読あり

田島卓也

整形外科 74 ( 10 ) 1072 - 1072 2023年9月

掲載種別：研究論文（学術雑誌）出版者・発行元：南江堂

DOI： 10.15106/j_seikei74_1072

Is the Small Ossicle of Type 1 Accessory Navicular a Cause of Foot Pain?-A Case Report. 査読あり

Yokoe T, Uemichi K, Tajima T, Chosa E

Medicina (Kaunas, Lithuania) 59 ( 9 ) 2023年8月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.3390/medicina59091562

Is the Small Ossicle of Type 1 Accessory Navicular a Cause of Foot Pain?—A Case Report 査読あり

Takuji Yokoe,Kazushi Uemichi,Takuya Tajima,Etsuo Chosa

medicina 59 ( 9 ) 1562 2023年8月

記述言語：英語掲載種別：研究論文（大学，研究機関等紀要）

DOI： doi.org/10.3390/medicina59091562

Risk factors associated with throwing injuries in young baseball players 査読あり

長澤誠, 田島卓也, 山口奈美, 森田雄大, 横江琢示, 大田智美, 石田康行, 帖佐悦男

Journal of Shoulder and Elbow Surgery 32 ( 8 ) 1673 - 1680 2023年8月

担当区分：責任著者記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Elsevier

Background
Few studies have retrospectively analyzed the relationship between joint range of motion (ROM) and muscle flexibility and shoulder and elbow throwing injuries in a large number of elementary school baseball players. The purpose of this study was to retrospectively identify the physical factors related to shoulder and elbow throwing injuries in younger baseball players.

Methods
A total of 2466 younger baseball players belonging to our Prefecture Rubber Baseball Federation who participated in medical check-ups from 2016 to 2019 were analyzed. Players completed a questionnaire and had a medical check-up that included a physical examination and ultrasonography. ROM (internal rotation [IR] angle and external rotation angle) of the shoulder and hip and the finger-to-floor distance and heel-to-buttock distance were measured. The straight leg raise was also performed. The results of two groups (normal group and injury group) were compared using the χ2 test, Mann-Whitney U test, and Student t test. Stepwise forward logistic regression models were developed to identify risk factors.

Results
On univariate analysis, nine of the 13 evaluated items showed significant decreases in ROM and muscle flexibility in the injury group. On multiple logistic regression analysis, grade, finger-to-floor distance, IR angle of the dominant side shoulder, and IR angle of the nondominant side hip were significantly associated with the occurrence of throwing injuries. Decreased total shoulder angle was observed not only on the dominant side but also on the nondominant side in the injury group.

Conclusion
Decreased ROM and muscle flexibility were risk factors for baseball-related throwing injuries in elementary school baseball players. To prevent shoulder and elbow throwing injuries, players, coaches, medical staff, and parents need to be aware of these findings.

Shear stress in the medial meniscus posterior root during daily activities.

Yokoe T, Ouchi K, Yamaguchi Y, Enzaki M, Tajima T, Chosa E

The Knee 43 176 - 183 2023年7月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Knee

Background: Medial meniscus posterior root (MMPR) tears have been reported to occur in middle-aged patients with minor trauma. However, the injury mechanism of MMPR tears remains unclear. The purpose of this study was to evaluate the shear stress in the MMPR during daily activities using a finite-element analysis. Methods: Subject-specific finite-element models of the knee joint of a healthy middle-aged subject were developed from computed tomographic and magnetic resonance images. A three-dimensional motion capture system “VICON” was used to capture four daily activities: walking, jogging, descending stairs, and landing. The knee joint reaction force was estimated using the AnyBody modeling system. Based on these procedures, the shear stress in the MMPR was calculated during each motion. The shear stress in the lateral meniscus posterior root (LMPR) was also measured to compare the stress between the MMPR and LMPR. Results: The shear stress in the MMPR increased as the knee flexion angle increased during each motion. Descending stairs caused more than two-fold greater stress in the MMPR than walking and a similar or greater amount of stress than jogging. The LMPR tended to receive more shear stress than the MMPR throughout each motion. Conclusions: The present study showed that descending stairs confers almost the same amount of shear stress to the MMPR as jogging. The results of the present study may suggest that descending motion of the knee is an important cause of MMPR tear, and the initiation of descending stairs should be delayed after MMPR repair.

DOI： 10.1016/j.knee.2023.06.008

Three-dimensional fine structures in deep fascia revealed by combined use of cryo-fixed histochemistry and low-vacuum scanning microscopy.

宮崎式サーフィン競技安全度評価を1シーズン使用してみて査読あり

小島岳史、柏木輝行、柏木悠吾、福嶋研人、吉田尚紀、石田翔太郎、帖佐悦男、田島卓也

九州・山口　スポーツ医・科学研究会誌 34 28 - 32 2023年7月

記述言語：日本語掲載種別：研究論文（研究会，シンポジウム資料等）出版者・発行元：Elsevier

Shear stress in the medial meniscus posterior root during daily activities 査読あり

Takuji Yokoe,Koki Ouchi,Yoichiro Yamaguchi,Masahiro Enzaki, Takuya Tajima,Etsuo Chosa

The Knee 43 176 - 183 2023年6月

記述言語：英語掲載種別：研究論文（大学，研究機関等紀要）出版者・発行元：Elsevier

DOI： doi.org/10.1016/j.knee.2023.06.008

Evaluation of Sit-to-Stand Movement in Older Adults with Locomotive Syndrome Using the Nintendo Wii Balance Board. Sensors 査読あり

Go Yamako, Niroshan G Punchihewa, Hideki Arakawa, Takuya Tajima, Etsuo Chosa

Sensors 2023年5月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.3390/s23073368

Ureter position and risk of ureteral injury during lateral lumbar interbody fusion 査読あり

Makoto Nagasawa,MD,Takuya Tajima,MD,PhD,Shuichi Kawagoe, MD,Nami Yamaguchi,MD,PhD, Yudai Morita,MD,Takuji Yokoe, MD,Tomomi Ota,MD,Toshihiko Izumi, MD, PhD,Yasuyuki Ishida, MD,Etsuo Chosa,MD,PhD

Journal of Clinical Medicine 32 ( 8 ) 1673 - 1680 2023年5月

記述言語：英語掲載種別：研究論文（大学，研究機関等紀要）出版者・発行元：Elsevier

DOI： doi.org/10.1016/j.jse.2023.01.034

Imazato H, Takahashi N, Hirakawa Y, Yamaguchi Y, Hiyoshi M, Tajima T, Chosa E, Sawaguchi A

Scientific reports 13 ( 1 ) 6352 2023年4月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Scientific Reports

Recent physiological studies have shown that the deep fascia has received much attention concerning clinical medicine; however, histological examination of the deep fascia has not been well established. In this study, we aimed to clarify and visualize the structure of the deep fascia by taking advantage of cryofixation techniques and low-vacuum scanning electron microscopy. As a result, the ultrastructural observations revealed three-dimensional stratification of the deep fascia composed of three layers: the first superficial layer consisting of collagen fibers extending in various directions with blood vessels and peripheral nerves; the second intermediate layer formed by single straight and thick collagen fibers with flexibility; and the third deepest layer, consisting of relatively straight and thin collagen fibers. We explored the use of two hooks to hold a piece of deep fascia in place through the course of cryo-fixation. A comparative observation with or without the hook-holding procedure would indicate the morphological adaptation to physiological stretch and contraction of the deep fascia. The present morphological approach paves the way to visualize three-dimensional ultrastructures for future biomedical studies including clinical pathophysiology.

DOI： 10.1038/s41598-023-33479-3

Evaluation of Sit-to-Stand Movement in Older Adults with Locomotive Syndrome Using the Nintendo Wii Balance Board.

Three‑dimensional fine structures in deep fascia revealed by combined use of cryo‑fixed histochemistry and low‑vacuum scanning microscopy 査読あり

Hiroyuki Imazato,NobuyasuTakahashi,Yusuke Hirakawa, Yoichiro Yamaguchi,Masaru Hiyoshi,Takuya Tajima, Etsuo Chosa, Akira Sawaguchi

Scientific reports 13 ( 1 ) 6352 2023年4月

記述言語：英語掲載種別：研究論文（大学，研究機関等紀要）出版者・発行元：Springer

DOI： doi.org/10.1038/s41598-023-33479-3

Yamako G, Punchihewa NG, Arakawa H, Tajima T, Chosa E

Sensors (Basel, Switzerland) 23 ( 7 ) 2023年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Sensors

Standing up from a chair is a mechanically demanding daily motion, and its biomechanics represent motor performance. In older adults with locomotive syndrome (LS), sit-to-stand (STS) movement with adequate postural control is essential to prevent falls. This study evaluated the characteristics of dynamic balance during STS movement on older adults with LS. A total of 116 participants aged ≥65 years were divided into Non-LS, LS stage 1, and LS stage 2 groups using the LS risk test. The participants were instructed to stand on the Nintendo Wii Balance Board as quickly as possible, and the STS movement was quantified using the vertical ground reaction force (VGRF) and center of pressure (CoP). The STS score, which represented dynamic balance, was significantly different among the groups (p < 0.001). The rate of VGRF development was significantly lower in the LS stages 1 and 2 than in the Non-LS group (p < 0.001). On the other hand, the total distance of the CoP path did not differ among the groups (p = 0.211). These findings indicated a reduction of postural control in older adults with LS. The STS score emphasized the importance of balance training to prevent falls in older adults with LS.

DOI： 10.3390/s23073368

Effect of the volume of resected discoid lateral meniscus on the contact stress of the tibiofemoral joint: A finite element analysis.

Risk factors of failure results after double-bundle reconstruction with autogenous hamstring grafts for isolated posterior cruciate ligament rupture cases 査読あり

Yudai Morita,Takuya Tajima,Nami Yamaguchi,Takuji Yokoe,Makoto Nagasawa,Tomomi Ota,Kouki Ouchi,Etsuo Chosa

Scientific reports 6192 2023年3月

記述言語：英語掲載種別：研究論文（大学，研究機関等紀要）

DOI： doi.org/10.1038/s41598-024-56953-y

Risk factors of failure results after double-bundle reconstruction with autogenous hamstring grafts for isolated posterior cruciate ligament rupture cases 査読あり

Yudai Morita,Takuya Tajima,Nami Yamaguchi,Takuji Yokoe,Makoto Nagasawa,Tomomi Ota,Kouki Ouchi,Etsuo Chosa

Scientific reports 6192 2023年3月

記述言語：英語掲載種別：研究論文（大学，研究機関等紀要）出版者・発行元：nature portfolio

DOI： doi.org/10.1038/s41598-024-56953-y

Yokoe T, Ouchi K, Matsumoto T, Tajima T, Chosa E

The Knee 42 57 - 63 2023年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Knee

Background: Partial meniscectomy is commonly performed for symptomatic patients with discoid lateral meniscus (DLM) if conservative treatment fails. However, the development of knee osteoarthritis and osteochondral lesion are detrimental postoperative complications. This study aimed to evaluate the effect of the volume of resected DLM on the contact stress of the tibiofemoral joint using a finite element analysis. Methods: Subject-specific finite-element models of the knee joint of a patient with DLM were developed from computed tomographic and magnetic resonance images. To evaluate the effect of partial meniscectomy on the contact stress in the lateral tibiofemoral joint, six knee models were created in the study (the native DLM, and five partially meniscectomized DLMs (according to the preserved width of the meniscus: 12 mm, 10 mm, 8 mm, 6 mm, and 4 mm)). Results: As the volume of resected DLM increased, higher contact stress was applied to the lateral tibiofemoral joint. Greater contact stress was applied to the preserved lateral meniscus than to the native DLM. Conclusions: From a biomechanical viewpoint, the native DLM was the most protective against lateral tibiofemoral contact stress in comparison to partially meniscectomized DLMs.

DOI： 10.1016/j.knee.2023.02.013

Insertion sites of the muscles attached to the clavicle: a cadaveric study of the clavicle.

Effect of the volume of resected discoid lateral meniscus on the contact stress of the tibiofemoral joint: A finite element analysis 査読あり

Takuji Yokoe, Koki Ouchi, Taisei Matsumoto, Takuya Tajima, Etsuo Chosa

The Knee 57 - 63 2023年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Elsevier

Imazato H, Takahashi N, Sawaguchi A, Hirakawa Y, Yamaguchi Y, Hiyoshi M, Tajima T, Chosa E

BMC musculoskeletal disorders 24 ( 1 ) 160 2023年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：BMC Musculoskeletal Disorders

Background: Clavicle fractures are common injuries, especially in young, active individuals. Operative treatment is recommended for completely displaced clavicle shaft fractures, and plate fixation is stronger than the use of intramedullary nails. Few studies have reported on iatrogenic injuries to the muscle attached to the clavicle during fracture surgery. The aim of this study was to clarify the area of the insertion sites of muscles attached to the clavicle in Japanese cadavers using gross anatomy and three-dimensional (3D) analysis. We also aimed to compare the effects of anterior plate templating and superior plate templating on clavicle shaft fractures using 3D images. Methods: Thirty-eight clavicles from Japanese cadavers were analyzed. We removed all clavicles to identify the insertion sites and measured the size of the insertion area of each muscle. Three-dimensional templating was performed on both the superior and anterior plates of the clavicle using data obtained from computed tomography. The areas covered by these plates on the muscles attached to the clavicle were compared. Histological examination was performed on four randomly selected specimens. Results: The sternocleidomastoid muscle was attached proximally and superiorly; the trapezius muscle was attached posteriorly and partly superiorly; and the pectoralis major muscle and deltoid muscles were attached anteriorly and partially superiorly. The non-attachment area was located mainly in the posterosuperior part of the clavicle. It was difficult to distinguish the borders of the periosteum and pectoralis major muscles. The anterior plate covered a significantly broader area (mean 6.94 ± 1.36 cm2) of the muscles attached to the clavicle than did the superior plate (mean 4.11 ± 1.52 cm2) (p < 0.0001). On microscopy, these muscles were inserted directly into the periosteum. Conclusion: Most of the pectoralis major and deltoid muscles were attached anteriorly. The non-attachment area was located mainly from the superior to posterior part of the clavicle midshaft. Both macroscopically and microscopically, the boundaries between the periosteum and these muscles were difficult to demarcate. The anterior plate covered a significantly broader area of the muscles attached to the clavicle than that by the superior plate.

DOI： 10.1186/s12891-023-06266-4

A Traumatic Neuroma Formation Following Fasciotomy for the Treatment of Tibialis Anterior Muscle Herniation: A Case Report.

Insertion sites of the muscles attached to the clavicle: a cadaveric study of the clavicle 査読あり

Hiroyuki Imazato, Nobuyasu Takahashi, Akira Sawaguchi, Yusuke Hirakawa, Yoichiro Yamaguchi, Masaru Hiyoshi, Takuya Tajima & Etsuo Chosa

BMC Musculoskeletal Disorders 2023年3月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：BMC

Yokoe T, Tajima T, Yamaguchi N, Morita Y, Chosa E

Medicina (Kaunas, Lithuania) 59 ( 3 ) 2023年2月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Medicina (Lithuania)

Muscle herniation of the lower extremity, such as tibialis anterior muscle herniation (TAMH), is not a rare cause of leg pain in athletes. However, a few studies have reported surgical treatment for TAMH, and the optimal surgical procedure remains controversial. Fasciotomy was reported to be effective for patients with TAMH. However, this procedure would be associated with a risk of intraoperative injury to the superficial peroneal nerve (SPN), although no previous literature has reported this complication. This case report aimed to report a case of bilateral TAMHs in which a traumatic neuroma of the SPN developed after fasciotomy. A 16-year-old baseball player presented with painful swelling lesions of the bilateral lower extremities (1 lesion on the right, 3 lesions on the left) after sports activities. An ultrasonographic evaluation showed swelling lesions of the anterolateral parts of the bilateral lower extremities in the standing position after dashing, while these lesions were not detected in the supine position. A fasciotomy of the crural fascia was performed after conservative treatment failed. Several days after surgery, the patient presented with weakened touch sensation over the dorsal area of the left foot. At the three-month follow-up examination, a swelling lesion with hard elasticity was identified. The palpation of this lesion caused a radiating sensation in the area supplied by the SPN. He was able to return to playing baseball six months after surgery. The patient was asymptomatic without palpation of the traumatic neuroma of the SPN at the latest follow-up examination. In conclusion, the present case report suggests that orthopedic surgeons need to consider the risk of iatrogenic injury to the SPN during fasciotomy for the treatment of TAMHs. However, there may be a risk of injuring the SPN because of the many variants of the course of the SPN within the compartment of the lower extremities.

DOI： 10.3390/medicina59030466

A Traumatic Neuroma Formation Following Fasciotomy for the Treatment of Tibialis Anterior Muscle Herniation:A Case Report 査読あり

Takuji Yokoe,Takuya Tajima,Nami Yamaguchi,Yudai Morita and Etsuo Chosa

medicina 2023年2月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：MDPI

Influence of the Tibial Tunnel Angle and Posterior Tibial Slope on "Killer Turn" during Posterior Cruciate Ligament Reconstruction: A Three-Dimensional Finite Element Analysis.

Yang F, Yokoe T, Ouchi K, Tajima T, Chosa E

Journal of clinical medicine 12 ( 3 ) 2023年1月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.3390/jcm12030805

Efficacy of Diagnosing Carpal Tunnel Syndrome Using the Median Nerve Stenosis Rate Measured on Ultrasonographic Sagittal Imagery: Clinical Case-Control Study 査読あり

Influence of the Tibial Tunnel Angle and Posterior Tibial Slope on "Killer Turn" during Posterior Cruciate Ligament Reconstruction: A Three-Dimensional Finite Element Analysis 査読あり

Fan Yang, Takuji Yokoe, Koki Ouchi, Takuya Tajima, Etsuo Chosa

Journal of Clinical Medicine 12 ( 3 ) 805 2023年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：MDPI

Okura T., Sekimoto T., Matsuoka T., Fukuda H., Hamada H., Tajima T., Chosa E.

Hand 18 ( 1_suppl ) 133S - 138S 2023年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Hand

Background: The purpose of the present study was to evaluate the usefulness of the median nerve stenosis rate (MNSR) measured on sagittal sonographic images of the median nerve in the diagnosis of carpal tunnel syndrome (CTS). Methods: The study population consisted of 45 hands from 37 patients with idiopathic CTS (CTS group), and 60 hands from 35 asymptomatic healthy subjects (control group). Carpal tunnel syndrome was diagnosed by clinical findings and positive electrophysiological study results. All patients and control subjects underwent ultrasonographic examination. At the carpal tunnel level, the transducer was placed longitudinally to the median nerve, and an image of the longitudinal median nerve was obtained. The minimum median nerve diameter (MND) was measured at the middle part of the capitate level, while the maximum MND was measured at the distal radioulnar joint level. The MNSR was calculated as (1 – minimum MND/maximum MND) × 100 (%). The cross-sectional area of the median nerve was also measured at the level of the pisiform. Results: On longitudinal sonographic images, the MNSR was significantly larger in the CTS group than the control group. When the cut-off value of the MNSR was 26.73%, the sensitivity and specificity were 91.1% and 80%, respectively. The area under the receiver operating characteristic curve was larger for the MNSR than for the cross-sectional area. Conclusion: The results suggest that the MNSR proposed in the present study may be useful as an auxiliary method for CTS diagnosis on ultrasonographic examination.

DOI： 10.1177/15589447211017225

Efficacy of Diagnosing Carpal Tunnel Syndrome Using the Median Nerve Stenosis Rate Measured on Ultrasonographic Sagittal Imagery: Clinical Case-Control Study. 査読あり

Toshiyuki Okura, Tomohisa Sekimoto, Tomomi Matsuoka, Hajime Fukuda, Hiroaki Hamada, Takuya Tajima, Etsuo Chosa.

Hand (NY) 18 ( 1_suppl ) 133S - 138S 2023年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：SAGE Publishing

Nakatake J., Arakawa H., Tajima T., Miyazaki S., Chosa E.

PeerJ 11 e16571 2023年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：PeerJ

Background: The objective kinematic assessments of activities of daily living are desired. However, the limited knowledge regarding age- and sex-related differences prevents the adaptation of these measurements to clinical settings and in-home exercises. Therefore, this study aimed to determine the effects of age and sex on joint and endpoint kinematics during a common activity of daily living, specifically, drinking from a glass. Methods: In total, 32 healthy adults (18 males and 14 females) aged 22–77 years performed a drinking task comprising reaching for a glass, bringing it forward and sipping, returning it, and placing the hand back to the starting position, which was recorded using a three-dimensional motion-capturing system. A two-way analysis of variance was used to statistically compare joint angles at five different time points and endpoint kinematic variables in the four drinking phases between older and younger age groups and sexes. Results: Wrist radial deviation was greater in older adults than in younger participants at all five different time points (F = 5.16–7.34, p ≤ 0.03, η2 = 0.14–0.21). Moreover, lesser shoulder abduction and greater shoulder internal rotation and forearm pronation when moving and returning the hand to the starting position were observed in the female group than in the male group (F = 4.21–20.03, p ≤ 0.0497, η2 = 0.13–0.41). Trunk flexion was lower in the female group than in the male group at all time points (F = 4.25–7.13, p ≤ 0.0485, η2 = 0.12–0.19). Regarding endpoint kinematics, the performance time in the reaching phase was longer in older adults than in younger individuals (F = 4.96, p = 0.03, η2 = 0.14). Furthermore, a shorter time while returning the hand to the starting position was observed in the female group than in the male group (F = 9.55, p < 0.01, η2 = 0.22). Conclusions: The joint kinematics of drinking were partially characterized by an age effect, whereas endpoint kinematics were scattered in all drinking phases. Sex-related effects in most upper-body motions and postures may cause rapid motions in females. Therefore, clinicians could use this knowledge for precise assessments and to suggest feasible in-home exercises.

DOI： 10.7717/peerj.16571

Risk factors associated with throwing injuries in young baseball players

Nagasawa M., Tajima T., Kawagoe S., Yamaguchi N., Morita Y., Yokoe T., Ota T., Izumi T., Ishida Y., Chosa E.

Journal of Shoulder and Elbow Surgery 32 ( 8 ) 1673 - 1680 2023年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Shoulder and Elbow Surgery

Background: Few studies have retrospectively analyzed the relationship between joint range of motion (ROM) and muscle flexibility and shoulder and elbow throwing injuries in a large number of elementary school baseball players. The purpose of this study was to retrospectively identify the physical factors related to shoulder and elbow throwing injuries in younger baseball players. Methods: A total of 2466 younger baseball players belonging to our Prefecture Rubber Baseball Federation who participated in medical check-ups from 2016 to 2019 were analyzed. Players completed a questionnaire and had a medical check-up that included a physical examination and ultrasonography. ROM (internal rotation [IR] angle and external rotation angle) of the shoulder and hip and the finger-to-floor distance and heel-to-buttock distance were measured. The straight leg raise was also performed. The results of two groups (normal group and injury group) were compared using the χ2 test, Mann-Whitney U test, and Student t test. Stepwise forward logistic regression models were developed to identify risk factors. Results: On univariate analysis, nine of the 13 evaluated items showed significant decreases in ROM and muscle flexibility in the injury group. On multiple logistic regression analysis, grade, finger-to-floor distance, IR angle of the dominant side shoulder, and IR angle of the nondominant side hip were significantly associated with the occurrence of throwing injuries. Decreased total shoulder angle was observed not only on the dominant side but also on the nondominant side in the injury group. Conclusion: Decreased ROM and muscle flexibility were risk factors for baseball-related throwing injuries in elementary school baseball players. To prevent shoulder and elbow throwing injuries, players, coaches, medical staff, and parents need to be aware of these findings.

DOI： 10.1016/j.jse.2023.01.034

東京オリンピックにおける7人制ラグビー競技のメディカルサポート査読あり

田島卓也, 帖佐悦男, 中村明彦

日本整形外科スポーツ医学会雑誌 43 ( 3 ) 105 - 110 2023年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：一般社団法人日本整形外科スポーツ医学会

7人制ラグビー競技に対するメディカルサポート体制をオリンピック組織委員会，日本ラグビーフットボール協会およびワールドラグビー（WR）と連携し構築した．無観客となったことやポリクリニックの常設もあり，「マッチデーメディカル」に特化して準備した．WRの定める医療体制指針に沿って，ピッチサイドメディカルケアに関する国際資格を保有するDrを配備した．競技日数6日間全68試合に対しメディカルスタッフとして有資格Dr 40名，歯科医3名，看護師3名，トレーナー6名の合計52名が出務した．11選手が医務室を受診し，1名が股関節脱臼骨折の診断で救急搬送された．Head Injury Assessmentによる脳振盪評価を6名に行い，うち4名が陽性となり退場した．

DOI： 10.34473/jossm.43.3_105

Objective Detection of High-Risk Tackle in Rugby by Combination of Pose Estimation and Machine Learning 査読あり

Nishio M., Nonaka N., Fujihira R., Murakami H., Tajima T., Yamada M., Maeda A., Seita J.

Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 13859 LNAI 215 - 228 2023年

掲載種別：研究論文（学術雑誌）出版者・発行元：Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

To provide suitable care for concussion, objective and timely detection of high-risk event is crucial. Currently it depends on monitoring by medical doctors, and there is a certain risk of missing high-risk events. A few attempts introducing video analysis have been reported, but those approaches require labeling by experts, which is skill-dependent, and time and cost consuming. To achieve objective detection of high-risk tackle without human intervention, we developed a method combining pose estimation by deep learning and pose evaluation by machine learning. From match videos of Japan Rugby Top League in 2016–2018 seasons, 238 low-risk tackles and 155 high-risk tackles were extracted. Poses of tackler and ball carrier were estimated by deep learning, then were evaluated by machine learning. The proposed method resulted AUC 0.85, and outperformed the previously reported rule-based method. Also, the features extracted by the machine learning model, such as upright positions of tackler/ball carrier, tackler’s arm dropped in extended position, were consistent with the known risk factors of concussion. This result indicates that our approach combining deep learning and machine learning opens the way for objective and timely detection of high-risk events in rugby and other contact sports.

DOI： 10.1007/978-3-031-29168-5_15

Ureter position and risk of ureteral injury during lateral lumbar interbody fusion

Hamanaka H., Tajima T., Kurogi S., Higa K., Nagai T., Kuroki T., Takamori H., Mukai S., Kamoto T., Chosa E.

Journal of Orthopaedic Science 2023年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Orthopaedic Science

Background: Ureteral injury during lateral lumbar interbody fusion (LLIF) is uncommon. However, it is a serious complication that may require additional surgery should it occur. The objective of this study was to evaluate whether there was any change in the position of the left ureter between preoperative biphasic contrast-enhanced CT scanned in the supine position and intraoperative scanning in the right lateral decubitus position after stent placement, to assess the risk of ureteral injury in the actual surgical position. Methods: The position of the left ureter scanned with the O-arm navigation system with the patient in the right lateral decubitus position and its position on preoperative biphasic contrast-enhanced CT images scanned with the patient in the supine position were investigated comparing their positions at the L2/3, L3/4, and L4/5 levels. Results: The ureter was located along the interbody cage insertion trajectory in 25 of 44 disc levels (56.8%) in the supine position, but in only 4 (9.5%) in the lateral decubitus position. The proportion of patients in whom the left ureter was located lateral to the vertebral body (along the LLIF cage insertion trajectory) at each level was 80% in the supine position and 15.4% in the lateral decubitus position at the L2/3 level, 53.3% in the supine position and 6.7% in the lateral decubitus position at the L3/4 level, and 33.3% in the supine position and 6.7% in the lateral decubitus position at the L4/5 level. Conclusion: The proportion of patients in whom the left ureter was located on the lateral surface of the vertebral body when the patient was in the actual surgical position (lateral decubitus position) was 15.4% at the L2/3 level, 6.7% at the L3/4 level, and 6.7% at the L4/5 level, suggesting that caution is required during LLIF surgery.

DOI： 10.1016/j.jos.2023.04.011

Does the contralateral healthy ankle of patient with ipsilateral mechanical lateral ankle laxity show greater lateral ankle laxity? Evaluation of the anterior talofibular ligament by stress ultrasonography

交通外傷による下腿切断症例における膝関節靭帯断裂と義肢歩行に関する研究－遷延する歩行障害と社会復帰の改善および変形性膝関節症予防を目指して. 査読あり

田島卓也

医研センタージャーナル 5 - 14 2023年

記述言語：日本語掲載種別：研究論文（学術雑誌）

Risk Factors of Loss of Knee Range of Motion after Primary Anterior Cruciate Ligament Reconstruction following Preoperative Recovery of Knee Range of Motion 査読あり

Takuji Yokoe, Takuya Tajima, Nami Yamaguchi, Yudai Morita, Etsuo Chosa

The Journal of Knee Surgery 2022年12月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Thieme

Yokoe T., Tajima T., Kawagoe S., Yamaguchi N., Morita Y., Chosa E.

BMC Musculoskeletal Disorders 23 ( 1 ) 887 2022年12月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：BMC Musculoskeletal Disorders

Background: A number of studies have evaluated risk factors for lateral ankle sprain (LAS) or chronic lateral ankle instability (CLAI). However, the definitive risk factors for LAS or CLAI remain controversial. The purpose of this study was to evaluate whether the contralateral healthy ankles of subjects with ipsilateral mechanical lateral ankle laxity (group I) show greater lateral ankle laxity in comparison to the healthy ankles of bilateral healthy controls (group B). Methods: From March 2020, anterior talofibular ligament (ATFL) lengths of young adult volunteers were cross-sectionally measured in non-stress and stress positions using a previously reported stress ultrasonography (US) procedure. The ATFL ratio (the ratio of stress ATFL/non-stress ATFL length) was calculated as an indicator of lateral ankle laxity. The manual anterior drawer test (ADT) was also performed. The US findings of healthy ankles from groups I and B were compared. Results: A total of 154 subjects in group B (mean age, 24.5 ± 2.8 years; male/female, 84/70) and 40 subjects in group I (mean age, 24.4 ± 2.3 years; male/female, 26/14) were included in the study. There was no significant difference in the ADT between the groups. There were no significant differences in the non-stress ATFL length (19.4 ± 1.8 vs. 19.3 ± 1.9, p = 0.84), stress ATFL length (20.8 ± 1.8 vs. 20.9 ± 1.9, p = 0.66), length change (1.5 ± 0.6 vs. 1.6 ± 0.6, p = 0.12) and ATFL ratio (1.08 ± 0.03 vs. 1.08 ± 0.03, p = 0.13) between the groups. Conclusion: No significant difference was detected between the contralateral healthy ankles of subjects with ipsilateral mechanical lateral ankle laxity and those of bilateral healthy controls.

DOI： 10.1186/s12891-022-05838-0

The Results of Orthopaedic Medical Examinations in Adolescent Amateur Weightlifters

Yokoe T., Tajima T., Yamaguchi N., Nagasawa M., Morita Y., Chosa E.

International Journal of Environmental Research and Public Health 19 ( 21 ) 2022年11月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：International Journal of Environmental Research and Public Health

Few studies have reported injuries and physical characteristics in adolescent weightlifters. The purpose of this study was to report the results of orthopaedic medical examinations in adolescent amateur weightlifters that were performed cross-sectionally from 2012 to 2019. The orthopaedic medical examination included physical examinations, generalized joint laxity, muscle and joint tightness, static alignment, muscle volume of the lower extremities, and medial longitudinal arch of the foot (the height from the tip of the navicular tubercle to the ground surface). A questionnaire survey regarding pain in the spine and lower extremities was also performed. A total of 99 adolescent weightlifters were included (male/female, 71/28; mean age, 16.2 ± 0.2 years). A total of 9.1% had received orthopaedic treatments, with spine injuries being the most prevalent. Of those who had not received orthopaedic treatments, 31.1% had pain in the spine or lower extremities (for >4 weeks). There were no significant gender differences in the incidence of pain or positive findings of physical examinations. Female weightlifters had a more reduced dorsiflexion of the ankle joint than male weightlifters (p = 0.02). Male weightlifters had a lower flexibility of the quadriceps than female weightlifters. The results of orthopaedic medical examinations in this study may help clinicians and young weightlifters to prevent injuries in competitive weightlifting.

DOI： 10.3390/ijerph192113947

Fixation of an Osteochondral Lesion of the Femoral Intercondylar Groove Using Autogenous Osteochondral Grafts and Bioabsorbable Pins in a Patient with Open Physes: A Case Report.

The Results of Orthopaedic Medical Examinations in Adolescent Amateur Weightlifters 査読あり

Takuji Yokoe, Takuya Tajima, Nami Yamaguchi, Makoto Nagasawa, Yudai Morita, Etsuo Chosa

International Journal of Environmental Research and Public Health 19 ( 21 ) 13947 2022年10月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：MDPI

The Results of Orthopaedic Medical Examinations in Adolescent Amateur Weightlifters 査読あり

Takuji Yokoe,Takuya Tajima,Nami Yamaguchi,Makoto Nagasawa,Yudai Morita and Etsuo Chosa

International Journal of Environmental Research and Public Health 19 13947 2022年10月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：International Journal fo Environmental Research and Public Health

Yokoe T, Tajima T, Yamaguchi N, Morita Y, Chosa E

Medicina (Kaunas, Lithuania) 58 ( 11 ) 2022年10月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Medicina (Lithuania)

Osteochondral lesion (OCL) of the patellofemoral (PF) joint is not an uncommon cause of knee pain, and surgery is needed when conservative treatment fails. However, there is a lack of evidence regarding the optimal surgical treatment for OCL of the PF joint. Fixation of OCLs using autogenous osteochondral grafts has been reported to be effective for OCL of the knee. However, in this surgical technique, the biomechanical strength of osteochondral grafts may not be sufficient in patients with open physes due to the specific quality of the cartilage and subchondral bone given their age. There is a lack of studies reporting fixation of the OCL located in the PF joint using autogenous osteochondral grafts. We herein report a case of OCL of the femoral intercondylar groove where autogenous osteochondral grafts augmented with bioabsorbable pins were used to fix the lesion in a 14-year-old patient with open physes. Preoperative MRI revealed a completely detached OCL of the intercondylar groove (36 mm × 20 mm). Although a total of four osteochondral grafts were harvested from the non-weightbearing area of the lateral femoral condyle, cartilage detached from one of the grafts. The quality of the osteochondral grafts was considered to be insufficient for stabilization of the OCL; thus, two bioabsorbable pins were additionally inserted following fixation of the lesion using three osteochondral grafts. After two years of follow-up, postoperative functional scores were favorable without knee pain. The present case suggests that fixation of the OCL using autogenous osteochondral grafts may not be appropriate for young patients with open physes.

DOI： 10.3390/medicina58111528

Fixation of an Osteochondral Lesion of the Femoral Intercondylar Groove Using Autogenous Osteochondral Grafts and Bioabsorbabale Pins in a Patient with Open Physes:A Case Report 査読あり

Takuji Yokoe,Takuya Tajima,Nami Yamaguchi,Yudai Morita and Etsuo Chosa

medicina 2022年10月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：MDPI

足部びまん性色素性絨毛結節性滑膜炎に対し，関節鏡下腫瘍切除術を施行した一例

外山宗樹, 横江琢示, 田島卓也, 山口奈美, 大田智美, 長澤誠, 森田雄大, 川越秀一, 帖佐悦男

整形外科と災害外科 71 ( 4 ) 725 - 729 2022年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

【背景】色素性絨毛結節性滑膜炎（Pigmented villonodular Synovitis, PVS）は関節滑膜や腱鞘に発生する比較的稀な良性腫瘍である．多くは膝関節周囲に発生し，足関節発生症例は稀である．今回，足部びまん性PVSに対して関節鏡下腫瘍切除術を行い，良好な短期成績を得た一例を経験したので報告する．【症例】23歳女性．数年前から左足部外側に腫瘤を自覚していたが，放置していた．しかしながら，腫瘤の消退を認めず前医を受診し，PVSの疑いで当科紹介となった．当科では関節鏡下腫瘍切除術を施行した．足関節前方および後足部鏡視下併用で足関節，足関節周囲，距骨下に病変を認め，関節鏡視下に腫瘍を切除した．術後病理診断ではびまん性PVSの診断であった．術後26ヶ月経過し，再発なく経過している．【結語】足部びまん性PVSに対し，足関節前方および後足部鏡視下併用での関節鏡下腫瘍切除術を施行し，良好な短期成績を得た一例を経験した．

DOI： 10.5035/nishiseisai.71.725

Head Injury Assessment in the Elite Level Rugby Union in Japan: Review of 3 Seasons

足部びまん性色素性絨毛結節性滑膜炎に対し，関節鏡下腫瘍切除術を施行した一例査読あり

外山宗樹,横江琢示,田島卓也,山口奈美,大田智美,長澤誠,森田雄大,川越秀一,帖佐悦男

整形外科と災害外科 71 ( 4 ) 725 - 729 2022年9月

記述言語：日本語掲載種別：研究論文（その他学術会議資料等）出版者・発行元：西日本整形・災害外科学会

Tajima T., Ota O., Nagayama M., Takahashi M., Yamada M., Ishiyama N., Yoshida I., Takemura M., Hara K., Akama T., Mitsumori N., Higashihara J., Toyama Y., Furuya M., Chosa E., Nakamura A.

International Journal of Sports Medicine 43 ( 10 ) 889 - 894 2022年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：International Journal of Sports Medicine

Head Injury Assessment (HIA) is the screening tool for head injury during a rugby game. The purpose of this study was to investigate the epidemiology of HIA in the Japan Rugby Top League (JRTL). The incidences of HIA, defined concussion (per 1,000 player-hours) and repeated concussions were evaluated in three seasons (2016-17, 2017-18, 2018-19; total 360 games). The HIA incidence rates were 12.7 (95% confidence interval 9.5-15.9), 20.8 (16.8-24.9), and 25.0 (20.5-29.5) in each season. HIA-1 criteria 2, which is applied for suspected concussion cases, was performed for 46 cases in the 2016-17 season, 81 cases in the 2017-18 season, and 88 cases in the 2018-19 season. The concussion incidence rates were significantly greater in the 2017-18 season (9.6/1000 player-hours, 95% confidence interval 6.8-12.4) and the 2018-19 season (14.4, 11-17.8) compared to the 2016-17 season (4.8, 2.8-6.8). The number of repeated concussion cases in the same season was 1 in the 2016-17 season and 4 in both the 2017-18 and 2018-19 seasons. This study confirmed significantly higher HIA and concussion incidence rates over time. Although the HIA system might have been established in the three seasons in JRTL, comprehensive management needs to be improved to prevent repeated concussions.

DOI： 10.1055/a-1810-6509

EPLINβ Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation.

健常者スポーツ，パラスポーツの相互理解を目指して‐合同メディカルチェックの試み- 査読あり

喜多恒允，田島卓也，横江琢示，森田雄大，長澤誠，山口奈美，帖佐悦男

日本臨床スポーツ医学会誌 30 ( 3 ) 695 - 702 2022年8月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：日本臨床スポーツ医学会

宮崎県の高校ラグビーにおけるメディカルサポート－３年間の外傷調査－査読あり

森田恭史,今里浩之,岩佐一真,横江琢示,森田雄大,比嘉聖,山口奈美,中村嘉宏,田島卓也,帖佐悦男,吉川大輔

九州・山口スポーツ医・科学研究会誌 33 37 - 40 2022年7月

記述言語：日本語掲載種別：研究論文（研究会，シンポジウム資料等）出版者・発行元：九州・山口スポーツ医・科学研究会

我々は宮崎県で開催されるラグビーの公式戦で要請のあった全試合にマッチデイドクター配備および後方支援病院を整備している．今回，15人制高校ラグビー宮崎県大会の外傷調査を行ったため報告する．

サーフィン競技会における医療体制の向上と重症事故発生予防を目的とした安全評価法の作成査読あり

石田翔太郎,小島岳史,帖佐悦男,田島卓也

九州・山口スポーツ医・科学研究会誌 33 6 - 11 2022年7月

記述言語：日本語掲載種別：研究論文（研究会，シンポジウム資料等）出版者・発行元：九州・山口スポーツ医・科学研究会

サーフィンは海上競技であり，陸上競技では助かる脳震盪でさえも死亡事故につながってしまう．そのため安全に競技会を開催するためにはドクター派遣だけではなくライフセーバー，救急車や後方支援病院との連携，AEDの設置が必要となる．しかし現在このような安全対策ができている競技会は少ない．今回安全度向上を目的としてサーフィン競技会専用の宮崎式安全評価法を作成した．
宮崎県では過去10年間で12例のサーフィン中（競技会外）の死亡例が発生しており，競技会中も重大事故が発生しうる．今回作成した評価法を今後の競技会で継続的に使用し、医療体制の向上に努める必要があると考える．

Miyazaki S, Funamoto T, Sekimoto T, Kurogi S, Ohta T, Nagai T, Tajima T, Imasaka M, Yoshinobu K, Araki K, Araki M, Choijookhuu N, Hishikawa Y, Chosa E

Acta histochemica et cytochemica 55 ( 3 ) 99 - 110 2022年6月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：日本組織細胞化学会

Epithelial protein lost in neoplasm (EPLIN) is an actin-associated cytoskeletal protein that plays an important role in epithelial cell adhesion. EPLIN has two isoforms: EPLINα and EPLINβ. In this study, we investigated the role of EPLINβ in osteoblasts using EPLINβ-deficient (EPLINβGT/GT) mice. The skeletal phenotype of EPLINβGT/GT mice is indistinguishable from the wildtype (WT), but bone properties and strength were significantly decreased compared with WT littermates. Histomorphological analysis revealed altered organization of bone spicules and osteoblast cell arrangement, and decreased alkaline phosphatase activity in EPLINβGT/GT mouse bones. Transmission electron microscopy revealed wider intercellular spaces between osteoblasts in EPLINβGT/GT mice, suggesting aberrant cell adhesion. In EPLINβGT/GT osteoblasts, α- and β-catenins and F-actin were observed at the cell membrane, but OB-cadherin was localized at the perinuclear region, indicating that cadherin-catenin complexes were not formed. EPLINβ knockdown in MC3T3-e1 osteoblast cells showed similar results as in calvaria cell cultures. Bone formation markers, such as RUNX2, Osterix, ALP, and Col1a1 mRNA were reduced in EPLINβ knockdown cells, suggesting an important role for EPLINβ in osteoblast formation. In conclusion, we propose that EPLINβ is involved in the assembly of cadherin-catenin complexes in osteoblasts and affects bone formation.

DOI： 10.1267/ahc.22-00027

特集スポーツ外傷･障害の予防と治療--TOKYO 2020が終了して成長期のスポーツ障害の予防と早期発見のポイント査読あり

EPLINβ Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation 査読あり

Shihoko Miyazaki, Taro Funamoto, Tomohisa Sekimoto, Syuji Kurigi, Tomomi Ohta, Takuya Nagai, Takuya Tajima, Mai Imasaka, Kumiko Yoshinobu, Kimi Araki, Masatake Asaki, Narantsog Choijookhuu, Yoshitaka Hishikawa, Etsuo Chosa

ACTA HISTOCHEMICA ET CYTOCHEMICA 55 ( 3 ) 99 - 110 2022年6月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Japan Society of Histochemistry and Cytochemistry

Remnant-Rreserved Single-Bundle Anterior Cruciate Ligament Augmentation in Multi-ligamentous Knee Reconstruction 査読あり

Takuya Tajima,MD, PhD NamiYamaguchi,MD,PhD Yudai Morita,MD Takuji Yokoe,MD Makotot Nagasawa,MD Tomomi Ota,MD Shuichi Kawagoe,MD Yoshihiro Nakamura, MD Etsuo Chosa,MD,PhD

The Journal of Knee Surgery 2022年6月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Thieme Medical Publishers,Inc.

田島卓也, 帖佐悦男

医学のあゆみ 281 ( 8 ) 812 - 814 2022年5月

担当区分：筆頭著者,　責任著者掲載種別：研究論文（学術雑誌）出版者・発行元：医歯薬出版

DOI： 10.32118/ayu28108812

A longer duration from injury to surgery is associated with preoperative deterioration of an isolated meniscal tear in patients aged 40 years or older

Elective one-stage all four-ligament reconstruction after open knee dislocation: A case report 査読あり

Takuji Yokoe, Takuya Tajima, Nami Yamaguchi, Etsuo Chosa

Journal of Orthopaedic Science 27 ( 3 ) 743 - 749 2022年5月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Elsevier

A longer duration from injury to surgery is associated with preoperative deterioration of an isolated meniscal tear in patients aged 40 years or older 査読あり

Takuji Yokoe, Takuya Tajima, Nami Yamaguchi, Yudai Morita, Etsuo Chosa

Journal of Orthopaedic Surgery (Hong Kong) 30 ( 2 ) 10225536221101692 2022年5月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：SAGE Publishing

Yokoe T., Tajima T., Yamaguchi N., Morita Y., Chosa E.

Journal of Orthopaedic Surgery 30 ( 2 ) 2022年5月

掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Orthopaedic Surgery

Purpose: To evaluate the preoperative deterioration of an isolated meniscal tear in patients aged 40 years or older, and whether time from injury to surgery is associated with worsening of a meniscal tear. Methods: Patients aged 40 years or older who underwent arthroscopic surgery for isolated meniscal tear between 2014 and 2019 were retrospectively reviewed. The diagnostic magnetic resonance imaging (MRI) findings and arthroscopic findings were compared to evaluate the deterioration of meniscal tears. Predictors of the development of meniscal tears; patient demographic factors, duration from injury to surgery (injury to MRI and MRI to surgery), and image findings were assessed. Results: A total of 58 patients (58 knees) were included (mean age, 55.9 ± 8.5 years; male/female, 31/27). An isolated meniscal tear deteriorated in 28 (48.3%). Compared patients with and without deteriorated meniscal tear, significant differences were found in the MRI grade of meniscal tear (p = 0.03), duration from injury to MRI (164.2 ± 167.9 vs 45.2 ± 48.7 days, p < 0.001), and from MRI to surgery (148.8 ± 91.1 vs 67.6 ± 56.7 days, p < 0.001). A multivariate regression analysis showed that the duration from injury to MRI (odds ratio [OR], 1.03; p < 0.001) and from MRI to surgery (OR, 1.02; p < 0.001) were independent predictors. Conclusion: Approximately 50% of isolated meniscal tears deteriorated preoperatively in patients aged 40 years or older. The duration from injury to surgery was an independent predictor of worsening of an isolated meniscal tear.

DOI： 10.1177/10225536221101692

Association between the Beighton Score and Stress Ultrasonographic Findings of the Anterior Talofibular Ligament in Healthy Young Women: A Cross-Sectional Study

Yokoe T., Tajima T., Yamaguchi N., Morita Y., Chosa E.

Journal of Clinical Medicine 11 ( 7 ) 2022年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Clinical Medicine

The Beighton score (BS) is widely used to evaluate generalized joint laxity. However, the association between the BS and lateral ankle laxity is unclear. This study compared the ultrasono-graphic (US) findings of the anterior talofibular ligament (ATFL) between high-(≥6) and low-(≤3) BS groups of healthy young women. The ATFL lengths of healthy young women were measured in the stress and nonstress positions using the previously reported technique from March 2021 to January 2022. The ATFL ratio (ratio of stress to nonstress ATFL length) was used as an indicator of lateral ankle laxity. The anterior drawer test (ADT) was performed. The correlation between the BS and US findings was also examined. A total of 20 (high-BS group) and 61 (low-BS group) subjects with a mean age of 23.8 ± 1.0 years were included. The high-BS group showed a higher grade of ADT than the low-BS group. No significant differences were found in the nonstress and stress ATFL lengths and ATFL ratio (1.10 ± 0.05 vs. 1.09 ± 0.05, p = 0.19) between the groups. No correlation was found between the BS and US findings. In conclusion, this study did not detect significant differences in the US findings of the ATFL between the high-and low-BS groups.

DOI： 10.3390/jcm11071759

The anterior talofibular ligament ratio was greater in young men with generalized joint laxity than in those without generalized joint laxity

Symptomatic discoid lateral meniscus shows a relationship between types and tear patterns, and between causes of clinical symptom onset and the age distribution 査読あり

Nami Yamaguchi, Etsuo Chosa, Takuya Tajima, Yudai Morita, Takuji Yokoe

Knee Surgery, Sports Traumatology, Arthroscopy 30 ( 4 ) 1436 - 1442 2022年4月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：European Society of Sports Traumatology, Knee Surgery and Arthroscopy

Effect of total hip arthroplasty on improving locomotive syndrome in hip disease patients: A prospective cohort study focused on total clinical decision limits stage 3

Miyazaki S, Tsuruta K, Yoshinaga S, Yamaguchi Y, Fujii Y, Arakawa H, Ochiai M, Kawaguchi T, Unoki A, Sakamoto T, Tajima T, Nakamura Y, Funamoto T, Hiyoshi M, Chosa E

Journal of Orthopaedic Science 2022年3月

掲載種別：研究論文（学術雑誌）

Yokoe T., Tajima T., Yamaguchi N., Morita Y., Chosa E.

Knee Surgery, Sports Traumatology, Arthroscopy 31 ( 5 ) 1994 - 2000 2022年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Knee Surgery, Sports Traumatology, Arthroscopy

Purpose: This study aimed to evaluate the relationship between generalized joint laxity (GJL) and stress ultrasonographic (US) findings of the anterior talofibular ligament (ATFL) of healthy young men. Methods: The ATFL lengths of healthy young men were consecutively measured in the stress and nonstress positions. The ATFL ratio was calculated as an indicator of lateral ankle laxity. GJL was evaluated using the Beighton score (BS), and a BS of ≥ 5 was considered GJL. The manual anterior drawer test (ADT) was also performed. The results of stress US and ADT were compared between subjects with and without GJL, and the correlation between GJL and US findings was examined. Results: A total of 13 subjects with GJL and 95 without GJL were included in the study. The mean BSs in the GJL and no-GJL groups were 5.9 ± 0.9 and 1.1 ± 1.3, respectively (p < 0.0001). The GJL group showed a higher grade of ADT than the no-GJL group (p < 0.0001). Significant differences were found in the stress ATFL length (23.6 ± 1.8 mm vs. 21.7 ± 1.8 mm, p = 0.002) and ATFL ratio (1.15 ± 0.06 vs. 1.07 ± 0.03, p < 0.0001) between the GJL and no-GJL groups. Spearman’s correlation coefficients showed a moderate correlation between the BS and ATFL ratio (r = 0.45, p < 0.0001). Conclusion: The present study showed significant differences in the ATFL ratio and stress ATFL length between young men with and without GJL. The BS was moderately correlated with the lateral ankle laxity in this population. Level of evidence: Level IV.

DOI： 10.1007/s00167-022-07109-w

Risk factors of loss of knee range of motion after primary anterior cruciate ligament reconstruction following preoperative recovery of knee range of motion

Yokoe T., Tajima T., Yamaguchi N., Morita Y., Chosa E.

Journal of Knee Surgery 36 ( 13 ) 1365 - 1373 2022年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Knee Surgery

The loss of knee range of motion (ROM) is not an uncommon complication after anterior cruciate ligament reconstruction (ACLR). However, the risk factors of loss of knee ROM remain debatable. The purpose of this study was to evaluate the incidence and risk factors of loss of knee ROM at 12 months after primary ACLR performed after regaining full knee ROM preoperatively. Consecutive patients who underwent primary ACLR after regaining full ROM between January 2014 and January 2020 were retrospectively reviewed. Patients who received a surgical arthrolysis within 12 months after ACLR or those who had a loss of knee ROM at 12 months postoperatively were defined as the loss of ROM group. Possible risk factors of loss of knee ROM, including patient demographic, preoperative, surgical, and postoperative factors, were assessed. The notch wide index and radiographic parameters of the tibial spines; medial tibial spine height (MTSH)/tibial length (TL), lateral tibial spine height (LTSH)/TL, and tibial spine width (TSW)/TL, were also assessed. A total of 141 patients (141 knees) were included (mean age, 25.8 ± 11.4 years; male/female, 56/85). Of the 141 patients, 3 received surgical arthrolysis within 12 months, and 23 had a loss of knee ROM at 12 months after ACLR. Compared patients with and without loss of knee ROM, significant differences were found in the age (p = 0.04), LTSH/TL (p = 0.02), and TSW/TL (p = 0.02). A multivariate regression analysis showed that the age (odds ratio [OR]; 1.05, 95% confidence interval [CI]: 1.01-1.09, p = 0.02), LTSH/TL (OR: 1.44, 95% CI: 1.01-2.1, p = 0.04), and TSW/TL (OR: 0.79, 95% CI: 0.65-0.97, p = 0.02) were identified as significant independent risk predictors of loss of knee ROM. This study showed that the incidence of loss of knee ROM at 12 months after primary ACLR was 18.4% (26/141). An older age, a higher LTSH/TL and a smaller TSW/TL may be associated with loss of knee ROM at 12 months after ACLR.

DOI： 10.1055/a-1934-0776

Objective detection of high-risk tackle in rugby by combination of pose estimation and machine learning

NISHIO Monami, NONAKA Naoki, FUJIHIRA Ryo, MURAKAMI Hidetaka, TAJIMA Takuya, YAMADA Mutsuo, MAEDA Akira, SEITA Jun

人工知能学会全国大会論文集 JSAI2022 ( 0 ) 1S5IS2a05 - 1S5IS2a05 2022年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：一般社団法人人工知能学会

To provide suitable care for concussion, objective and timely detection of high-risk tackle is crucial in the field of contact sports, such as rugby. Currently it depends on monitoring by match officials, and there is a certain risk of missing high-risk events. A few attemps introducing video analysis have been reported, but those approaches require labeling by experts, which is skill-dependent, and also time and cost consuming. To achieve objective and timely detection of high-risk tackle, we developed a method combining pose estimation by deep-learning and pose evaluation by machine learning. From match videos of Japan Rugby Top League in 2016~2018 seasons, 238 low-risk tackle and 155 high-risk tackle were extracted. Poses of tackler and ball carrier were estimated by deep learning, then were evaluated by machine learning. The proposed method resulted AUROC-score 0.85 and outperformed the previously reported rule-based method. Also, the features extracted by the machine learning model, such as upright positions of tackler/ball carrier, tackler's arm dropped in extended position, were consistent with the known risk factors. This result indicates that our approach combining deep-learning and machine learning opens the way for objective and real-time detection of high-risk tackle in rugby and other contact sports.

DOI： 10.11517/pjsai.jsai2022.0_1s5is2a05

End-to-End High-Risk Tackle Detection System for Rugby 査読あり

Nonaka N., Fujihira R., Nishio M., Murakami H., Tajima T., Yamada M., Maeda A., Seita J.

IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops 2022-June 3549 - 3558 2022年

掲載種別：研究論文（学術雑誌）出版者・発行元：IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops

Reducing risk of severe injury such as concussion is a high priority for any contact sports. In rugby, Head Injury Assessment (HIA) protocol has been introduced to identify and protect players showing symptoms of concussion and having potential risk of concussion. However, on-field decisions by officials are sometimes difficult and subjective, and HIA is affordable only for elite leagues since it requires medical specialists. To make rugby matches more safe, we aim to develop a system to detect high-risk tackles, potential triggers of concussion, based on deep learning models. Our system takes rugby match video, then first identifies frame with tackle, subsequently detects location of tackle and estimate pose of the ball carrier and the tackler, and finally evaluate the risk of tackle using posture pair of players. Among the model combinations we have examined, the best performance was achieved with the combination of ResNet (2+1)D as tackle frame selection model, RetinaNet as tackle detection model and CenterTrack as pose estimation model. Evaluation using test data, a set of short clips from broadcasted rugby match videos, showed our system was able to detect 50% of high-risk tackles without any human intervention. This result opens a path for automated systems to detect high-risk events, leading to less expensive and more objective monitoring not only for rugby but also for any contact sports.

DOI： 10.1109/CVPRW56347.2022.00399

End-to-End High-Risk Tackle Detection System for Rugby. 2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW), New Orleans, LA, USA, 2022 査読あり

Nonaka N, Fujihira R, Nishio M, Murakami H, Tajima T, Yamada M, Maeda A, Seita J

CVPR 2022年

記述言語：英語掲載種別：研究論文（学術雑誌）

Head Injury Assessment in the Elite Level Rugby Union in Japan:Review of 3 Seasons 査読あり

Takuya Tajima,Osamu Ota,Masataka Nagayama,Masayasu Takahashi,Mutsuo Yamada,Nobuo Ishiyama,Ichiro Yoshida,Masahiro Takemura,Kenji Hara,et al

International Journal of Sports Medicine 2022年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Thieme

Does the contralateral healthy ankle of patient with ipsilateral mechanical lateral ankle laxity show greater lateral ankle laxith? Evaluation of the anterior talofibular ligament by stress ultrasonography 査読あり

Takuji Yokoe,Takuya Tajima,Shuichi Kawagoe,Nami Yamaguchi,Yudai Morita and Etsuo Chosa

BMC Musculoskeletal Disorders 23 ( 1 ) 887 2022年

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：BMC

Takuya Tajima, Nami Yamaguchi, Yudai Morita, Makoto Nagasawa, Tomomi Ota, Yoshihiro Nakamura, Takuji Yokoe, Etsuo Chosa

Journal of Knee Surgery 2021年12月

掲載種別：研究論文（学術雑誌）

Turner’s syndrome associated with discoid lateral meniscus and Blount’s disease: a case report 査読あり

Kita T., Tajima T., Chosa E.

BMC Musculoskeletal Disorders 22 ( 1 ) 449 2021年12月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：BMC Musculoskeletal Disorders

Background: Turner’s syndrome, discoid meniscus, and Blount’s disease have all been studied in isolation, but, to the best of our knowledge, there have been no studies reporting a patient with all three. Thus, the first case of Turner’s syndrome with discoid meniscus and Blount’s disease is presented. Case presentation: A 5-year-old Japanese girl with a history of Turner’s syndrome and Blount’s disease complained of pain in her left knee. Magnetic resonance imaging showed a discoid lateral meniscus tear, and arthroscopic partial meniscectomy was performed, providing a good outcome. Conclusions: In this report, some possible explanations regarding the concomitant presence of these three diseases are discussed. A possible explanation in this case is that the patient with Turner’s syndrome had a discoid lateral meniscus that might have been induced by some genetic factors associated with Turner’s syndrome, and then the discoid lateral meniscus might have been the mechanical stress that caused Blount’s disease.

DOI： 10.1186/s12891-021-04336-z

The current clinical practice of general orthopaedic surgeons in the treatment of lateral ankle sprain: a questionnaire survey in Miyazaki, Japan 査読あり

Yokoe T., Tajima T., Yamaguchi N., Morita Y., Chosa E.

BMC Musculoskeletal Disorders 22 ( 1 ) 636 2021年12月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：BMC Musculoskeletal Disorders

Background: Lateral ankle sprain (LAS) is one of the most common musculoskeletal injuries. Numerous studies regarding LAS have been performed. However, there are few studies evaluating the current clinical practice of orthopaedic surgeons regarding LAS. The purpose of this study was to evaluate the current clinical practice of general orthopaedic surgeons in the treatment of LAS. Methods: A questionnaire survey was conducted from September 2020 to December 2020 in Miyazaki, Japan, to evaluate the clinical practice of general orthopaedic surgeons in the treatment of LAS. The survey was composed of 12 questions that were developed with consideration of the recommendations in the current clinical practice guidelines (CPGs) published by the Dutch orthopaedic society. The questions in this study were focused on the diagnosis, conservative treatment, rehabilitation, and the criteria for return to sports (RTS). Results: The survey response rate was 82.7% (129/156). Among the respondents, 95.3% did not consider the Ottawa Ankle Rules in the decision to perform plain radiography for patients. Rehabilitation following LAS was performed in 58.9% of patients. Eighty-five (65.9%) of the surgeons used only one factor as the criterion for RTS. The absence of pain was the most frequently used criterion (45.7%). No objective criteria were used for the RTS decision in athletes with LAS. Conclusions: The present study suggested that most general orthopaedic surgeons do not provide the care for patients with LAS recommended by the current CPGs. No objective criteria for the RTS decision are used for athletes with LAS.

DOI： 10.1186/s12891-021-04527-8

A case of nail-patella syndrome with osteochondral lesion of the lateral femoral condyle accompanied with anomalies of anterior horns of the menisci and lateral femoral condyle 査読あり

Takuji Yokoe, Takuya Tajima, Nami Yamaguchi, Yudai Morita, Etsuo Chosa

Journal of Orthopaedic Science 2021年10月

掲載種別：研究論文（学術雑誌）

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上下肢3か所に多発した腱鞘巨細胞腫の治療経験

當瀬雅大, 大田智美, 坂本武郎, 田島卓也, 山口奈美, 長澤誠, 森田雄大, 横江琢示, 川越秀一, 帖佐悦男, 川野啓介

整形外科と災害外科 70 ( 4 ) 749 - 753 2021年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

〔はじめに〕腱鞘巨細胞腫は手指に多く発生することが知られているが，多発例の報告は稀である．上下肢3か所に多発した稀な腱鞘巨細胞腫の症例を経験したので報告する．〔症例〕45歳男性で，約4年前に左示指に釣り針が刺さった同時期より左示指，左肘，左膝の腫瘤を自覚した．MRIで3か所とも関節外にT1強調画像で等から軽度高信号，T2強調画像で低信号，造影で不均一に造影される境界明瞭な腫瘤を認めた．左膝腫瘤の切除生検を施行した結果，腱鞘巨細胞腫の診断に至った．生検と画像所見より，多発腱鞘巨細胞腫と判断し，3か所同時に腫瘍摘出術を施行し，最終診断もすべて腱鞘巨細胞腫であった．〔考察〕我々が渉猟しえた限りでは多発例は32報告で，上下肢に及ぶ2か所発生例，3病変の発生例はそれぞれ1例のみであった．本症例は上下肢に及ぶ3病変の多発例であり，稀な症例であると思われた．〔結語〕本症例は再発リスク因子が多く，今後の慎重な経過観察が必要と考える．

DOI： 10.5035/nishiseisai.70.749

高校空手選手における貧血調査

木戸義隆, 田島卓也, 山口奈美, 長澤誠, 大田智美, 森田雄大, 横江琢示, 川越秀一, 帖佐悦男

整形外科と災害外科 70 ( 4 ) 703 - 706 2021年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

【目的】高校空手選手の貧血について調査したので報告する．【対象・方法】2012-2019年の宮崎県某高校空手部1年生68名（男子39名，女子29名）を対象とし，2015-2019年の国民体育大会宮崎県代表候補選手のうち高校1年生160名（男子114名，女子46名）と比較した．【結果】男子はHb＜13 g/dL，女子はHb＜12 g/dLを貧血とした．【結果】空手選手では30.8％（男子28.2％，女子34.5％）に貧血を認め，全例正球性貧血だった．他競技の貧血例は陸上女子選手1例だった．空手選手の貧血群と非貧血群で血清鉄，網赤血球，フェリチン，不飽和鉄結合能に有意差はなく，貧血と鉄欠乏に関連はなかった．【考察】空手部の貧血が全例正球性貧血であったことから，空手の突き動作に伴い頻回に足を踏み込む動作で足底血管にて溶血をきたしたと考えた．空手選手のメディカルサポートの際には，貧血を考慮する必要があると考えられた．

DOI： 10.5035/nishiseisai.70.703

Internal Fixation of a Lateral Inverted Osteochondral Fracture of the Talus (LIFT) Lesion Using an Innovative Surgical Approach: Inverting the Capsulo-Lateral Fibulotalocalcaneal Ligament (LFTCL)–Fibular Periosteum Complex

Yokoe T, Tajima T, Yamaguchi N, Ota T, Nagasawa M, Morita Y, Chosa E

Journal of Foot and Ankle Surgery 60 ( 5 ) 1054 - 1059 2021年9月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Foot and Ankle Surgery

Osteotomy of the distal fibula or anterolateral corner of the tibia is usually required to fix a displaced osteochondral fracture of the talus that is located central to posterior area of the lateral talar dome. However, osteotomy is an invasive procedure and is associated with complications, including nonunion, persistent pain, and hardware-related problems. Lateral inverted osteochondral fracture of the talus (LIFT) lesion is an extremely rare type of displaced osteochondral lesion of the talus. We describe a case in which a LIFT lesion was fixed using an innovative surgical approach, inverting capsulo-lateral fibulotalocalcaneal ligament (LFTCL)–fibular periosteum complex, with a favorable short-term clinical outcome.

DOI： 10.1053/j.jfas.2021.03.005

上下肢3ヶ所に多発した腱鞘巨細胞腫の治療経験査読あり

當瀬雅大, 大田智美, 坂本武郎, 田島卓也, 山口奈美, 長澤誠, 森田雄大, 横江琢示, 川越秀一, 帖佐悦男, 川野啓介

整形外科と災害外科 2021年9月

掲載種別：研究論文（学術雑誌）

高校空手選手における貧血調査査読あり

木戸義隆, 田島卓也, 山口奈美, 長澤誠, 大田智美, 森田雄大, 横江琢示, 川越秀一, 帖佐悦男

整形外科と災害外科 2021年9月

掲載種別：研究論文（学術雑誌）

The current clinical practice of general orthopaedic surgeons in the treatment of lateral ankle sprain: a questionnaire survey in Miyazaki, Japan

Yokoe T, Tajima T, Yamaguchi N, Morita Y, Chosa E

BMC Musculoskeletal Disorders 2021年7月

掲載種別：研究論文（学術雑誌）

Symptomatic discoid lateral meniscus shows a relationship between types and tear patterns, and between causes of clinical symptom onset and the age distribution

Yamaguchi N, Chosa E, Tajima T, Morita Y, Yokoe T

Knee Surgery, Sports Traumatology, Arthroscopy 2021年6月

掲載種別：研究論文（学術雑誌）

Non-anatomical placement adversely affects the functional performance of the meniscal implant: a finite element study

Shriram D, Yamako G, Kumar G.P, Chosa E, Cui F, Subburaj K

Biomechanics and Modeling in Mechanobiology 2021年6月

掲載種別：研究論文（学術雑誌）

Turner’s syndrome associated with discoid lateral meniscus and Blount’s disease: a case report

Kita T, Tajima T, Chosa E

BMC Musculoskelet Disord 2021年5月

掲載種別：研究論文（学術雑誌）

Remnant-Preserved Single-Bundle Anterior Cruciate Ligament Augmentation in Multi-ligamentous Knee Reconstruction 査読あり

Tajima T., Yamaguchi N., Morita Y., Yokoe T., Nagasawa M., Ota T., Kawagoe S., Nakamura Y., Chosa E.

Journal of Knee Surgery 36 ( 10 ) 1095 - 1101 2021年5月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Knee Surgery

This study was conducted to present remnant-preserving anterior cruciate ligament (ACL) augmentation as a useful option for partial ACL injury in multiligament knee injury (MLKI) cases, which may also contribute to conserving graft resources. The present study involved patients diagnosed with MLKI at our institute from Spring 2006 to February 2021. A total of 71 MLKI cases were provided surgery due to knee instability and disability. For every patient, an arthroscopic diagnostic was performed to ensure that ACL tear and a remnant were present. When the ACL remnant was classified into group 2, 3, or 4 of Nakamae's classification, remnant-preserved single bundle ACL augmentation was performed. Graft selection and the combination of injured ligaments were evaluated. The side-to-side difference under an anterior tibial load of 134 N with an arthrometer and the leg symmetry index at 60 degrees/s were measured. The present procedure was performed for five cases (male/female: 4/1, mean age: 33.6 years). The mean follow-up period was 26.4 months. The combination of torn ligaments was as follows: 3 cases of ACL + medial collateral ligament, one case of ACL + posterior cruciate ligament, and one case of ACL + posterolateral corner. An ACL augmentation graft was performed using an ipsilateral gracilis tendon in 2 cases, a contralateral full semitendinosus tendon in 2 cases, and the ipsilateral distal 1/2 of the semitendinosus tendon in 1 case. The mean side-to-side difference was 1.07 ± 0.4 mm. The mean leg symmetry index was 82.6 ± 12.2% in knee extension and 96.3 ± 9.9% in knee flexion. Although the present study was a small case series, the remnant-preserved single-bundle ACL augmentation for MLKI surgery provided good clinical outcome and conserved the graft resource. Even in the MLKI case, this technique is one of the useful surgical options. The level of evidence of this study is level IV (case series).

DOI： 10.1055/s-0042-1749603

座談会ラグビーワールド･カップからみえてきたスポーツ医学の実際と課題

Predictors of Spondylolysis on Magnetic Resonance Imaging in Adolescent Athletes With Low Back Pain

Takuji Yokoe, Takuya Tajima, Hiroshi Sugimura, Shinichirou Kubo, Shotarou Nozaki, Nami Yamaguchi, Yudai Morita, Etsuo Chosa

Orthopaedic Journal of Sports Medicine 2021年4月

掲載種別：研究論文（学術雑誌）

Turner’s syndrome associated with discoid lateral meniscus and Blount’s disease: a case report

Kita T, Tajima T, Chosa E

BMC Musculoskeletal Disorders 2021年3月

掲載種別：研究論文（学術雑誌）

Effect of total hip arthroplasty on improving locomotive syndrome in hip disease patients: A prospective cohort study focused on total clinical decision limits stage 3 査読あり

Shigeaki Miyazaki, Kurumi Tsuruta, Saori Yoshinaga, Yoichiro Yamaguchi, Yoshinori Fujii, Hideaki Arakawa, Masaru Ochiai, Tsubasa Kawaguchi, Aya Unoki, Takero Sakamoto, Takuya Tajima, Yoshihiro Nakamura, Taro Funamoto, Masaru Hiyoshi, Etsuo Chosa

Journal of Orthopaedic Science 21 2021年2月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1016/j.jos.2020.12.028

田島卓也, 守屋拓朗, 高森草平, 井澤秀典, 大野均, 德永祥尭, 黒田良祐

臨床整形外科 56 ( 1 ) 4 - 14 2021年1月

掲載種別：研究論文（学術雑誌）出版者・発行元：株式会社医学書院

DOI： 10.11477/mf.1408201881

Symptomatic discoid lateral meniscus shows a relationship between types and tear patterns, and between causes of clinical symptom onset and the age distribution 査読あり

Yamaguchi N., Chosa E., Tajima T., Morita Y., Yokoe T.

Knee Surgery, Sports Traumatology, Arthroscopy 30 ( 4 ) 1436 - 1442 2021年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Knee Surgery, Sports Traumatology, Arthroscopy

Purpose: Discoid meniscus is a congenital abnormality of the lateral meniscus and is seen more frequently in East Asia. The purpose of this study was to retrospectively assess the relationship between discoid lateral meniscus (DLM) types and tear patterns and causes of age-specific clinical symptom onset. Methods: Of 1650 arthroscopic surgeries over a 20-year period, 138 (105 patients) were performed for DLM and were evaluated in this study. The mean age at surgery was 21.5 ± 15.8 years. The DLM type was classified by Watanabe’s classification, and tear patterns were classified by the modified Bin’s classification as simple horizontal, complicated horizontal, longitudinal, radial, complex, and no tear. Additionally, patients were divided by age group (< 10, 10–19, 20–39, 40–59, and ≥ 60 years) and classified according to the causes of clinical symptom onset as follows: sports activities, minor trauma in daily living, and no traumatic episode. Results: The DLM was complete in 78 (56.5%) knees and incomplete in 60 (43.5%); no Wrisberg type DLM was observed. Simple horizontal and complicated horizontal tears were significantly more frequent in complete DLM, whereas radial tears and no tears were significantly more frequent in incomplete DLM (p < 0.0001). When classified by age group, 74 (53.6%) knees with DLMs were found in teenagers. Sports activities caused symptom onset significantly more often in teenagers, no traumatic episode caused symptom onset in patients aged < 10 years, and minor trauma in daily living caused symptom onset in patients aged 40–59 years and ≥ 60 years (p < 0.0001). No relationship was found between the age distribution and tear patterns; however, the absence of tears tended to be more common in teenaged patients, and complicated horizontal tears were more common in patients over 20 years of age. Conclusion: Symptomatic DLM occurred most often in teenagers. A relationship was identified between the DLM types and tear patterns, which could be helpful in preoperative planning. Causes of clinical symptom onset in patients with DLM were characterised by age group, which might help clinicians to suspect the presence of DLM. Level of evidence: Level IV.

DOI： 10.1007/s00167-021-06635-3

Predictors of Spondylolysis on Magnetic Resonance Imaging in Adolescent Athletes With Low Back Pain 査読あり

Yokoe T., Tajima T., Sugimura H., Kubo S., Nozaki S., Yamaguchi N., Morita Y., Chosa E.

Orthopaedic Journal of Sports Medicine 9 ( 4 ) 2325967121995466 2021年1月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Orthopaedic Journal of Sports Medicine

Background: Spondylolysis and undiagnosed mechanical low back pain (UMLBP) are the main causes of low back pain (LBP) in adolescent athletes. No studies have evaluated the difference in clinical and radiographic factors between these 2 conditions. Furthermore, it remains unclear which adolescent athletes with LBP should undergo advanced imaging examination for spondylolysis. Purpose: To compare the clinical and radiographic factors of adolescent athletes with spondylolysis and UMLBP who did not have neurological symptoms or findings before magnetic resonance imaging (MRI) evaluation and to determine the predictors of spondylolysis findings on MRI. Study Design: Cohort study, Level of evidence, 3. Methods: The study population included 122 adolescent athletes aged 11 to 18 years who had LBP without neurological symptoms or findings and who underwent MRI. Of these participants, 75 were ultimately diagnosed with spondylolysis, and 47 were diagnosed with UMLBP. Clinical factors and the following radiographic parameters were compared between the 2 groups: spina bifida occulta, lumbar lordosis (LL) angle, and the ratio of the interfacet distance of L1 to that of L5 (L1:L5 ratio, %). A logistic regression analysis was performed to evaluate independent predictors of spondylolysis on MRI scans. Results: Significantly more athletes with spondylolysis were male (82.7% vs 48.9%; P <.001), had a greater LL angle (22.8° ± 8.1° vs 19.3° ± 8.5°; P =.02), and had a higher L1:L5 ratio (67.4% ± 6.3% vs 63.4% ± 6.6%; P =.001) versus athletes with UMLBP. A multivariate analysis revealed that male sex (odds ratio [OR], 4.66; P <.001) and an L1:L5 ratio of >65% (OR, 3.48; P =.003) were independent predictors of positive findings of spondylolysis on MRI scans. Conclusion: The study findings indicated that sex and the L1:L5 ratio are important indicators for whether to perform MRI as an advanced imaging examination for adolescent athletes with LBP who have no neurological symptoms and findings.

DOI： 10.1177/2325967121995466

A case of nail-patella syndrome with osteochondral lesion of the lateral femoral condyle accompanied with anomalies of anterior horns of the menisci and lateral femoral condyle

Efficacy of Diagnosing Carpal Tunnel Syndrome Using the Median Nerve Stenosis Rate Measured on Ultrasonographic Sagittal Imagery: Clinical Case-Control Study

Okura T., Sekimoto T., Matsuoka T., Fukuda H., Hamada H., Tajima T., Chosa E.

Hand 2021年

掲載種別：研究論文（学術雑誌）

ヤング率を傾斜させた人工股関節ステムの生体力学的評価

中井亮佑, 落合清秀, 和佐宗樹, 花田修治, 帖佐悦男, 山子剛

日本機械学会九州支部講演論文集 2021年

掲載種別：研究論文（学術雑誌）

小児の運動・スポーツの意義

帖佐悦男

日本整形外科スポーツ医学会雑誌 2021年

掲載種別：研究論文（学術雑誌）

Yokoe T., Tajima T., Yamaguchi N., Morita Y., Chosa E.

Journal of Orthopaedic Science 2021年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Orthopaedic Science

DOI： 10.1016/j.jos.2021.09.004

The Ratio of Stress to Nonstress Anterior Talofibular Ligament Length on Ultrasonography: Normative Values

Yokoe T., Tajima T., Kawagoe S., Yamaguchi N., Morita Y., Chosa E.

Orthopaedic Journal of Sports Medicine 9 ( 11 ) 23259671211056305 2021年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Orthopaedic Journal of Sports Medicine

Background: Stress ultrasonography (US) has been shown to be a valid procedure for evaluating chronic anterior talofibular ligament (ATFL) injury. The ratio of stress/nonstress ATFL length (ATFL ratio) as measured on US is clinically useful; however, there are no published normative data concerning this ratio. Purpose: To report a normative value of the ATFL ratio on US and evaluate the relationships between sex, generalized joint laxity (GJL), and the grade of anterior drawer test (ADT). Study Design: Cross-sectional study; Level of evidence, 3. Methods: The ATFL lengths were prospectively measured in the stress and nonstress positions (manual maximal anterior drawer position) for participants with noninjured ankles from March 2020 to March 2021. GJL was defined as a Beighton score ≥4. A manual ADT was also performed. The ATFL ratio was calculated, and the relationships between sex, GJL, and ADT grade were evaluated. Results: A total of 333 ankles in 184 participants (mean age, 24.5 ± 2.7 years; range, 20-33 years) were eligible for the analysis. GJL was found in 69 ankles (20.7%). The mean ATFL ratio was 1.08 ± 0.04 (95% CI, 1.08-1.09; range, 1.01-1.24), and there was a significant difference between male (1.07 ± 0.04; 95% CI, 1.07-1.08; range, 1.02-1.23) and female (1.09 ± 0.04; 95% CI, 1.08-1.10; range, 1.01-1.24) ankles (P =.001). In male ankles, the ATFL ratio was significantly greater in participants with GJL (1.11 ± 0.06 vs 1.07 ± 0.03; P =.02) or a higher grade of ADT (grade 2 vs grade 1: 1.11 ± 0.06 vs 1.07 ± 0.03, P =.002). These findings were not observed in female ankles. Conclusion: The normative value of the ATFL ratio on stress US was 1.07 ± 0.04 in men and 1.09 ± 0.04 in women. The ATFL ratio was affected by the presence of GJL in men but not in women. These findings will be useful for future studies seeking to establish the cutoff value of the ATFL ratio for diagnosing chronic lateral ankle stability on stress US.

DOI： 10.1177/23259671211056305

特集アキレス腱断裂診療のコツと最近のトピックスアキレス腱断裂の診断

田島卓也, 帖佐悦男

整形･災害外科 63 ( 12 ) 1627 - 1635 2020年11月

掲載種別：研究論文（学術雑誌）出版者・発行元：金原出版

DOI： 10.18888/se.0000001518

コリジョンスポーツにおける至適な頸部周囲筋力と頸椎アライメントの解明：重症頭頸部外傷を予防するために査読あり

田島卓也、山口奈美、黒木修司、森田雄大、帖佐悦男

デサントスポーツ科学 41 ( 0 ) 135 - 144 2020年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：公益財団法人石本記念デサントスポーツ科学振興財団

コリジョンスポーツ選手においては頸椎の退行変性をきたすことがあり，変性が進行すると頚髄損傷などの重大事故につながる危険性も示唆されている．頸椎退行変性とくにアライメント異常には頸部周囲筋力バランスが関与していることも報告されている．コリジョンスポーツ選手の頸椎退行変性予防さらには重症頸椎頚髄損傷予防を目的とし，頸部屈曲・伸展筋力バランスの異常が頸椎退行変性やアライメント異常に関与していると仮説のもと柔道選手及びラグビー選手の頸部周囲筋力と頸椎レントゲンの関連を解析した．対象はメディカルチェック時に頸部周囲筋力測定を実施した柔道選手168名（22-32歳），ラグビー選手203名（18-30歳）であり，このうち頸椎レントゲン検査を受けたのは柔道群55名，ラグビー群58名であった．身長・体重・頸部屈曲筋力・伸展筋力および屈曲/伸展筋力比とも柔道群が有意に大きかったが，体重比は両群間に有意差はなかった．頸椎アライメントにおいては正常群と前弯消失群，後弯変形群の筋力測定値に関連は認めなかったが柔道群においてＳ状変形群の伸展筋力が有意に大きかった（正常群：331.7±48.4N,Ｓ状変形群：420±50.2Ｎ.p<0.05）．屈曲/伸展筋力比では柔道群の前弯消失群（0.67），後弯変形群（0.63），およびラグビー群の椎間腔狭小化有り群（0.54）において正常群（柔道:0.78, ラグビー：0.68）と比較し有意に低下していた（p<0.05）．屈曲/伸展筋力比ひいては相対的な屈曲筋力の低下が柔道におけるアライメント異常およびラグビーにおける椎間腔狭小化に関与している可能性が示唆された．

DOI： 10.57488/descente.41.0_135

Takuya Tajima、Nami Yamaguchi、Yudai Morita、Makoto Nagasawa、Tomomi Ota、Yoshihiro Nakamura、Takuji Yokoe、Etsuo Chosa

The Journal of Knee Surgery 1 - 8 2020年5月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1055/s-0040-1710376

選手がベストパフォーマンスを発揮するために―チームドクターの役割の変遷― 招待あり査読あり

田島卓也, 中村明彦, 帖佐悦男

日本整形外科スポーツ医学会雑誌 40 ( 3 ) 229 - 235 2020年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：一般社団法人日本整形外科スポーツ医学会

日本ラグビーフットボール協会では万全なメディカルサポート体制を構築すべく種々の施策を行なっている．従来，チームメディカルスタッフとしてドクター1名，アスレティックトレーナー2～3名体制で選手のみならずチームスタッフも含めて日本選手団全員の健康管理を行なっている．チームメディカルスタッフの役割・ミッションとしては「選手がベストパフォーマンスを発揮できるようにサポート」することであり，①外傷障害への対応②コンディション管理③ドーピングコントロール教育・対応があげられる．そのミッションを遂行するためには，整形外科以外の知識・対応，コミュニケーション・連携，などが重要となる．

DOI： 10.34473/jossm.40.3_229

宮崎大学医学部整形外科のスポーツイベントへの帯同状況

上腕骨小頭離断性骨軟骨炎手術例と野球検診の関係査読あり

岩佐一真、長澤誠、田島卓也、山口奈美、大田智美、森田雄大、帖佐悦男

九州・山口スポーツ医・科学研究会誌 31 35 - 37 2019年7月

記述言語：日本語掲載種別：研究論文（学術雑誌）

サッカー日本女子代表（なでしこジャパン）のメディカルサポートを通して招待あり査読あり

山口奈美、田島卓也、長澤誠、森田雄大、帖佐悦男、園田典生

日本整形外科スポーツ医学会雑誌 39 ( 2 ) 10 - 14 2019年5月

記述言語：日本語掲載種別：研究論文（学術雑誌）

全国レベルの高校空手道部の新入生メディカルチェック：3年間の結果より査読あり

北堀貴史、森田雄大、長澤誠、黒木修司、山口奈美、田島卓也、石田康行、帖佐悦男

日本臨床スポーツ医学会誌 27 ( 2 ) 266 - 272 2019年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

ヘモグロビンは滑膜からADAMTS-5，-9の発現を亢進させる：関節血症の軟骨変性に及ぼす影響査読あり

田島卓也、谷口昇、山口奈美、帖佐悦男

日本関節鏡・膝・スポーツ整形外科学会雑誌 44 ( 1 ) 292 - 293 2019年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

ACL損傷後・再建術後のスポーツ復帰：〜100%を超える復帰〜現場におけるACL損傷膝・再建膝の復帰プログラム査読あり

田島卓也、中川匠

日本整形外科スポーツ医学会雑誌 39 ( 1 ) 2019年

記述言語：日本語掲載種別：研究論文（学術雑誌）

アスリートが本番で実力を発揮するための方策　ラグビー帯同ドクターの立場から査読あり

井上貴司、坂根正孝、守屋拓朗、田島卓也、中村明彦

関節外科 37 ( 10 ) 1115 - 1119 2018年10月

記述言語：日本語掲載種別：研究論文（学術雑誌）

成長期・育成世代のラグビー選手に対する外傷・脳振盪後の復帰プロトコル査読あり

田島卓也，帖佐悦男

Monthly Book MEDICAL REHABILITATION ( 228 ) 108 - 115 2018年10月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Double crushを呈していた橈尺骨骨幹部骨折後尺骨神経障害の1例査読あり

藤田貢司、石田康行、谷口昇、田島卓也、山口奈美、長澤誠、森田雄大、関本朝久、帖佐悦男

整形外科と災害外科 67 ( 4 ) 674 - 676 2018年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）

DOI： 10.5035/nishiseisai.67.674

脳震盪・頚部外傷発生時の現場対応、リハビリテーションと競技復帰査読あり

坂根正孝、村上秀孝、田中誠人、田島卓也、山田睦雄

日本臨床スポーツ医学会誌 26 ( 3 ) 344 - 347 2018年8月

記述言語：日本語掲載種別：研究論文（学術雑誌）

サッカー日本女子代表：メディカルサポートの実際と課題査読あり

山口奈美、石田康行、田島卓也、森田雄大、帖佐悦男、園田典生

日本整形外科スポーツ医学会雑誌 38 ( 3 ) 5 - 9 2018年7月

記述言語：日本語掲載種別：研究論文（学術雑誌）

遠隔医療システムを用いたラグビー新サポートシステムの可能性～ITシステムが新たな安全対策のソリューションになり得るか～査読あり

中村嘉宏、帖佐悦男、田島卓也、吉川大輔、黒木修司、比嘉聖

日本整形外科スポーツ医学会雑誌 38 ( 3 ) 44 - 50 2018年7月

記述言語：日本語掲載種別：研究論文（学術雑誌）

宮崎県少年野球検診−検診結果と可動域の関係− 査読あり

長澤誠、石田康行、谷口昇、田島卓也、山口奈美、三橋龍馬、川野啓介、帖佐悦男

日本関節鏡・膝・スポーツ整形外科學會雑誌 43 ( 2 ) 562 - 563 2018年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Larson変法を用いた膝後外側支持機構再建術査読あり

山口奈美、田島卓也、石田康行、谷口昇、大田智美、長澤誠、帖佐悦男

日本関節鏡・膝・スポーツ整形外科學會雑誌 43 ( 2 ) 506 - 507 2018年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

2019年ワールドカップ、2020年オリンピックに向けたラグビーチームのメディカルサポート査読あり

板根正孝、守屋拓朗、井上貴司、井澤秀典、田島卓也、中村明彦

Bone Joint Nerve 8 ( 2 ) 239 - 243 2018年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

外側広範型上腕骨小頭離断性骨軟骨炎の手術成績を左右する因子査読あり

石田康行、長澤誠、谷口昇、田島卓也、山口奈美、大田智美、帖佐悦男

日本関節鏡・膝・スポーツ整形外科學會雑誌 43 ( 1 ) 16 - 17 2018年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

脛骨付着部を温存した自家半健様筋健グラフトによるＭＣＬ再建術の術後短期成績査読あり

田島卓也、山口奈美、谷口昇、石田康行、大田智美、長澤誠、帖佐悦男

日本関節鏡・膝・スポーツ整形外科學會雑誌 43 ( 1 ) 180 - 181 2018年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

ＩＰ関節の色素沈着を伴い発症した関節リウマチ症例

濱田浩朗、古結英樹、関本朝久、田島卓也、天野正宏、帖佐悦男

宮崎県医師会医学会誌 42 ( 1 ) 97 - 104 2018年3月

記述言語：日本語掲載種別：研究論文（大学，研究機関等紀要）

当院における Fibrin Clot を用いた関節鏡視下半月縫合術の治療経験（共著）査読あり

戸田雅, 田島卓也, 山口奈美, 帖佐悦男

整形外科と災害外科 66 ( 2 ) 254 - 257 2017年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

スポーツ活動者の外傷性肩関節前方不安定症に対する鏡視下バンカート修復術の成績（共著）査読あり

横江琢示, 石田康行, 田島卓也, 帖佐悦男

日本整形外科スポーツ医学会雑誌 37 ( 1 ) 59 - 63 2017年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

自家ハムストリングス腱を用いた二重束膝前十字靭帯再建術後の３種類の膝固定期間と骨孔拡大の関係査読あり

田島卓也

整形外科 68 ( 2 ) 184 - 186 2017年2月

記述言語：日本語掲載種別：研究論文（学術雑誌）

ラグビーワールドカップ2019におけるメディカルネットワーク構築（共著）査読あり

田島卓也, 中村明彦, 帖佐悦男

臨床スポーツ医学 34 ( 2 ) 106 - 110 2017年2月

記述言語：日本語掲載種別：研究論文（学術雑誌）

膝関節外側滑膜ヒダ障害による弾発膝を来した1例査読あり

三股奈津子, 石田康行, 谷口昇, 田島卓也, 山口奈美, 大田智美, 帖佐悦男

九州・山口スポーツ医・科学研究会誌 28 78 - 80 2016年7月

記述言語：日本語掲載種別：研究論文（学術雑誌）

BTBと薄筋腱を併用した2重束ACL再建術の臨床成績と画像評価

田島卓也、石田康行、谷口昇、山口奈美、帖佐悦男

JOSKAS 41 ( 1 ) 116 - 117 2016年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Remnant-preservint, selective single-bundle augmentation of the anterior cruciate ligament using a bone-patellar tendon-bone autograft: a technical note(共著) 査読あり

Takuya Tajima, Etsuo Chosa, Nami Yamaguchi, Noboru Taniguchi, Yasuyuki Ishida

The Knee 2016年2月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1016/j.knee.2015.11.024

横江琢示, 田島卓也, 中村嘉宏, 山口奈美, 黒木修司, 帖佐悦男

整形外科と災害外科 65 ( 1 ) 54 - 57 2016年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

宮崎大学医学部整形外科は宮崎県と連携し，積極的にスポーツイベントへのメディカルサポートを行なっている．平成25年度に当科が行ったメディカルサポート状況につき調査した．宮崎大学医学部整形外科所属の医師が出務した宮崎県外・海外へのチーム帯同や医事運営は10件でその期間は3日間から32日間であった．内訳としては，U-17女子サッカー日本代表帯同が3件，国民体育大会（国体）宮崎県選手団帯同が3件，国体サッカー少年の部帯同が3件，全国高校ラグビー大会帯同が1件であった．宮崎県内で開催されたスポーツイベントのマッチドクター，医事運営への出務は46競技会62日間であった．内訳としては，ラグビー32日，サッカー11日，柔道8日，マラソン2日でその他競技が9日であった．出務医師総数は15人で8人はスポーツドクター資格保持者であった．当科でのスポーツイベントへの医師派遣の現状および課題について報告する．

DOI： 10.5035/nishiseisai.65.54

宮崎県における2014春季キャンプに対するメディカルサポート報告－キャンプの地の総合的メディカルサポート体制の構築にむけて－(共著) 査読あり

小島岳史, 田島卓也, 帖佐悦男, 石田康行, 河原勝博, 山口奈美, 日吉優, 永井琢哉, 園田典生, 松岡知己, 井上篤, 田島直也, 山本惠太郎, 樋口潤一

九州・山口スポーツ医・科学研究会誌 ( 27 ) 4 - 7 2015年7月

記述言語：日本語掲載種別：研究論文（学術雑誌）

フルスレッドアンカーを用いたスーチャーブリッジ法後のアンカー孔の検討(共著) 査読あり

石田康行, 帖佐悦男, 谷口昇, 田島卓也, 山口奈美, 大田智美, 中村志保子

JOSKAS 40 ( 3 ) 587 - 590 2015年6月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Takuya Tajima, Etsuo Chosa, Katsuhiro Kawahara, Nami Yamaguchi.

Arthroscopy 31 ( 4 ) 651 - 658 2015年4月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1016/j.arthro.2014.10.015

自家ハムストリング腱を用いたbi-socket法によるPCL再建術の術後短期成績査読あり

田島卓也, 河原勝博, 山口奈美, 石田康行, 谷口昇, 帖佐悦男

日本関節鏡・膝・スポーツ整形外科学会雑誌（JOSKAS） 40 ( 1 ) 176 - 177 2015年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Comprehensive Safety Manegement and Assessment at Rugby Football Competitions. 招待あり査読あり

Tajima T, Chosa E, Kawahara K, Nakamura Y, Yoshikawa D, Yamaguchi N, Kashiwagi T.

International Journal of sports medicine 35 1012 - 1016 2014年12月

記述言語：英語掲載種別：研究論文（学術雑誌）

ランニング障害とその対策：股関節招待あり査読あり

田島卓也, 帖佐悦男

臨床スポーツ医学 31 ( 9 ) 884 - 889 2014年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）

春シーズンに開催されたラグビー競技会で発生した熱中症の2例査読あり

山口洋一朗, 山口奈美, 田島卓也, 帖佐悦男

九州・山口スポーツ医・科学研究会誌 26 100 - 102 2014年7月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Os acromialeを伴った腱板断裂に対する鏡視下腱板修復，Os acromiale切除術査読あり

石田康行, 帖佐悦男, 谷口昇, 田島卓也, 山口奈美, 大田智美, 中村志保子

JOSKAS 39 ( 3 ) 564 - 568 2014年6月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Comprehensive Safety Manegement and Assessment at Rugby Football Competitions. 査読あり

Tajima T, Chosa E, Kawahara K, Nakamura Y, Yoshikawa D, Yamaguchi N, Kashiwagi T.

International Journal of sports medicine 2014年5月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1055/s-0034-1372634

子どもからのロコモ予防の重要性－運動器検診を通して－招待あり査読あり

山口奈美, 山本惠太郎, 河原勝博, 石田康行, 田島卓也, 帖佐悦男

日本臨床スポーツ医学会誌 22 ( 2 ) 250 - 253 2014年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

ラグビー選手における頚椎退行変性の予防－頚部体幹コアトレーニング導入の効果－査読あり

田島卓也, 帖佐悦男, 河原勝博, 山口奈美, 中村嘉宏

日本整形外科スポーツ医学会雑誌 34 ( 1 ) 80 - 84 2014年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

前十字靭帯不全膝における半月縫合術の成績査読あり

森田雄大, 河原勝博, 田島卓也, 山口奈美, 矢野浩明, 石田康行, 村上恵美, 大田智美, 中村志保子, 大塚記史, 帖佐悦男

整形外科と災害外科 63 ( 2 ) 260 - 262 2014年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

ハムストリング腱を用いた2重束ACL再建術後の膝固定期間の相違と骨孔拡大の関係査読あり

田島卓也, 石田康行, 山口奈美, 帖佐悦男, 山本惠太郎

JOSKAS　日本関節鏡・膝・スポーツ整形外科学会雑誌 39 170 - 171 2014年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

前十字靭帯不全膝における半月縫合術の成績

森田雄大, 河原勝博, 田島卓也, 山口奈美, 矢野浩明, 石田康行, 村上恵美, 大田智美, 中村志保子, 大塚記史, 帖佐悦男

整形外科と災害外科 63 ( 2 ) 260 - 262 2014年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

【はじめに】われわれは，膝前十字靱帯（以下，ACL）損傷と半月損傷を合併した症例で，諸事情により半月縫合術を単独で施行した症例について，ACL再建術時に半月の状態を評価検討した．【対象・方法】対象は2006年1月から2012年12月の期間に，ACL損傷に半月損傷を合併した症例のうち半月縫合のみ施行した症例6例6膝である．これらについて半月損傷形態，縫合方法，再鏡視所見，待機期間との関連について検討した．【結果】6膝中2膝に再断裂を認め，いずれも待機期間の長い症例であった．【考察】ACL不全膝で半月縫合術を施行した症例は，半月単独損傷で半月縫合術を施行した症例と比較し再断裂は高率であった．待機期間の長い症例で再断裂の可能性が高くなることが示唆された．ACL不全膝に対する半月縫合術は半月単独損傷に比べ再断裂の危険性は高いが，癒合率は66.7％であり禁忌でないと思われた．

DOI： 10.5035/nishiseisai.63.260

ラグビー選手における頚椎退行変性の予防－頚部体幹コアトレーニング導入の効果－査読あり

田島卓也, 帖佐悦男, 河原勝博, 山口奈美, 中村嘉宏

日本整形外科スポーツ医学会雑誌 34 80 - 84 2013年8月

記述言語：日本語掲載種別：研究論文（学術雑誌）

ラグビー選手の上腕二頭筋腱遠位端断裂に対する自家ハムストリング腱を用いた再建術の経験査読あり

梅﨑哲矢, 田島卓也, 山本惠太郎, 山口奈美, 帖佐悦男

日本整形外科スポーツ医学会雑誌 33 ( 3 ) 321 - 326 2013年7月

記述言語：日本語掲載種別：研究論文（学術雑誌）

変形性膝関節症患者の??骨高原骨折??骨骨幹部骨折術後偽関節に対し１期的にTKA施行した3例査読あり

小島岳史, 柏木輝行, 田島卓也, 帖佐悦男

Journal of Japanese Orthopaedic Society of Knee ,Arthroscopy and Sports Medicine 38 ( 2 ) 244 - 245 2013年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

BTBと薄筋腱を併用した2重束ACL再建術査読あり

田島卓也, 山本惠太郎, 河原勝博, 石田康行, 山口奈美, 大田智美, 帖佐悦男

JOSKAS　日本関節鏡・膝・スポーツ整形外科学会雑誌 38 54 - 55 2013年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

変形性膝関節症患者の脛骨高原骨折・脛骨骨幹部骨折術後偽関節に対し1期的にTKA施行した3例

小島岳史, 柏木輝行, 田島卓也, 帖佐悦男

JOSKAS 38 ( 2 ) 244 - 245 2013年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

鏡視下腱板修復術後における非吸収性アンカー孔の検討査読あり

石田康行、帖佐悦男、山本惠太郎、田島卓也、山口奈美、大田智美

Journal of Japanese Orthopaedic Society of Knee, Arthroscopy and Sports Medicine 38 ( 1 ) 16 - 17 2013年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

膝外側円板状半月に合併した大腿骨内顆離断性骨軟骨炎の治療経験査読あり

山口奈美、山本惠太郎、石田康行、河原勝博、田島卓也、大田智美、帖佐悦男

Journal of Japanese Orthopaedic Society of Knee, Arthroscopy and Sports Medicine 38 ( 1 ) 150 - 151 2013年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

ＢＴＢと薄筋腱を併用した２重束ＡＣＬ再建術査読あり

田島卓也、山本惠太郎、河原勝博、石田康行、山口奈美、大田智美、帖佐悦男

Journal of Japanese Orthopaedic Society of Knee, Arthroscopy and Sports Medicine 38 ( 1 ) 54 - 55 2013年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

BTBと薄筋腱を併用した2重束ACL再建術

田島卓也, 山本惠太郎, 河原勝博, 石田康行, 山口奈美, 大田智美, 帖佐悦男

JOSKAS 38 ( 1 ) 54 - 55 2013年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

膝外側円板状半月に合併した大腿骨内顆離断性骨軟骨炎の治療経験

山口奈美, 山本惠太郎, 石田康行, 河原勝博, 田島卓也, 大田智美, 帖佐悦男

JOSKAS 38 ( 1 ) 150 - 151 2013年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

鏡視下腱板修復術後における非吸収性アンカー孔の検討

石田康行, 帖佐悦男, 山本惠太郎, 田島卓也, 山口奈美, 大田智美

JOSKAS 38 ( 1 ) 16 - 17 2013年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Anterior cruciate ligament reconstruction in a patient with Athetoid cerebral palsy: a case report

Tajima T., Chosa E., Yamamoto K., Kawahara K., Yamaguchi N., Watanabe S.

Sports Medicine, Arthroscopy, Rehabilitation, Therapy and Technology 4 ( 1 ) 36 2012年10月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Sports Medicine, Arthroscopy, Rehabilitation, Therapy and Technology

Recent years have seen ACL reconstruction performed in a broad range of patients, regardless of age, sex or occupation, thanks to great advances in surgical techniques, instrumentation and the basic research. Favorable results have been reported; however, we have not been able to locate any reports describing ACL reconstruction in patients with athetoid cerebral palsy.We present herein a previously unreported anterior cruciate ligament (ACL) reconstruction performed in a patient with athetoid cerebral palsy. The patient was a 25-year-old woman with level II athetoid cerebral palsy according to the Gross Motor Function Classification System. She initially injured her right knee after falling off a bicycle. Two years later, she again experienced right-knee pain and a feeling of instability. A right-knee ACL tear and avulsion fracture was diagnosed upon physical examination and confirmed with magnetic resonance imaging (MRI) and X-ray examination at that time. An ACL reconstruction using an autologous hamstring double-bundle graft was performed for recurrent instability nine years after the initial injury. Cast immobilization was provided for 3 weeks following surgery and knee extension was restricted for 3 months with the functional ACL brace to prevent hyperextension due to involuntary movement. Partial weight-bearing was started 1 week postoperatively, with full weight-bearing after 4 weeks. The anterior drawer stress radiography showed a 63% anterior displacement of the involved tibia on the femur six months following the surgery, while the contralateral knee demonstrated a 60% anterior displacement of the tibia. The functional ACL functional brace was then removed. A second-look arthroscopy was performed 13 months after the ACL reconstruction, and both the anteromedial and posterolateral bundles were in excellent position as per Kondo's criteria. The Lachman and pivot shift test performed under anesthesia were also negative. An anterior drawer stress radiography of the involved knee at 36 months following surgery showed a 61% anterior translation of the tibia. The preoperative symptoms of instability resolved and the patient expressed a high degree of satisfaction with the result of her surgery. © 2012 Tajima et al.; licensee BioMed Central Ltd.

DOI： 10.1186/1758-2555-4-36

Effect of genu recurvatum on the anterior cruciate ligament-deficient knee during gait

手術適応厳選前後の鏡視下腱板修復術の成績

石田康行, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也, 山口奈美, 大田智美, 中村志保子, 帖佐悦男

整形外科と災害外科 61 ( 3 ) 346 - 349 2012年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

以前，鏡視下腱板修復術（ARCR）の成績を報告した．術後臨床成績は良好であったが大，広範囲断裂例，術前筋萎縮進行例で再断裂が多かった．この反省を踏まえ適応を厳選しARCRを行ってきた．今回，適応厳選前後の成績を調査したので報告する．2005年10月から2009年7月の前期に行った80肩と2009年8月から2010年8月の後期に行った58肩を対象とした．両期での断裂形態，断裂腱板筋萎縮，腱板修復状態，臨床成績を調査した．大，広範囲断裂，筋萎縮進行例の割合が有意差はなかったが後期で減少していた．腱板修復状態は後期で有意に改善していた．臨床成績は両期とも術後有意に改善していた．適応を厳選すれば再断裂例は減少していた．一時修復不能例の多くは陳旧性腱板断裂の有症状化と考えられる．個々の症例に合わせた保存療法も含めた治療法の選択が必要である．近年のARCRの成績から若年の修復可能な症候性腱板断裂例は修復不能例を予防するためにも積極的な手術が推奨される．

DOI： 10.5035/nishiseisai.61.346

手術適応厳選前後の鏡視下腱板修復術の成績査読あり

石田康行、矢野浩明、山本惠太郎、河原勝博、田島卓也、山口奈美、大田智美、中村志保子、帖佐悦男

整形外科と災害外科　別冊 61 ( 3 ) 346 - 349 2012年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Ｍenisｃo Capsular Separationに対する鏡視下半月縫合術の検討査読あり

小島岳史、花堂祥治、矢野良英、柏木輝行、塩﨑猛、田島卓也、帖佐悦男

九州・山口スポーツ医・科学研究会誌 24 89 - 92 2012年8月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Kawahara K., Sekimoto T., Watanabe S., Yamamoto K., Tajima T., Yamaguchi N., Chosa E.

Knee Surgery, Sports Traumatology, Arthroscopy 20 ( 8 ) 1479 - 1487 2012年8月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Knee Surgery, Sports Traumatology, Arthroscopy

Purpose: This study aimed to investigate the effects of genu recurvatum, which is considered to carry a high risk for anterior cruciate ligament (ACL) injury, on healthy and post-ACL injury gait and lower extremity muscle strength. Methods: Subjects were 36 patients with ACL-deficient knee and 40 healthy controls without pain or restricted range of motion of the lower extremity during gait. The knee joints of all subjects were examined; those with over 10° hyperextension of both knees were defined as exhibiting genu recurvatum. On this basis, the subjects were further subdivided into two groups: with or without genu recurvatum. A three-dimensional motion analysis system and force plates were used for gait analysis. Isokinetic dynamometers were used to measure knee muscle strength. Results: There were no differences in joint angles, joint moments, or components of ground reaction force during gait or in knee strength for the healthy control subjects with and without genu recurvatum. ACL-deficient subjects without genu recurvatum showed a decrease in knee angles during the stance phase and a decrease in extension moments during the early stance phase compared with ACL-deficient subjects with genu recurvatum and controls. In contrast, neither knee angles nor extension moments during the stance phase differed significantly between ACL-deficient subjects with genu recurvatum and controls. Conclusions: This study provides clinically relevant information regarding the effects of genu recurvatum on gait parameters. The results suggest that in ACL injuries, the presence of genu recurvatum alters gait pattern. Consideration of the presence of genu recurvatum would be useful during rehabilitation following ACL injuries or ACL reconstruction. Level of evidence: II. Prospective comparative study. © 2011 Springer-Verlag.

DOI： 10.1007/s00167-011-1701-z

Arthroscopic anatomical double-bundle anterior cruciate ligament reconstruction for asian patient using a bone-patellar tendon-bone and gracilis tendon composite autograft: A technical note

鏡視下腱板修復術後における吸収性アンカー孔の拡大

石田康行, 山本惠太郎, 田島卓也, 山口奈美, 大田智美, 帖佐悦男

JOSKAS 37 ( 3 ) 391 - 394 2012年6月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Menisco Capsular Separation に対する鏡視下半月縫合術の検討査読あり

小島岳史、花堂祥冶、矢野良英、柏木輝行、田島卓也、帖佐悦男

宮崎整形外科懇話会論文集 ( 16 ) 43 - 44 2012年6月

記述言語：日本語掲載種別：研究論文（学術雑誌）

ラグビ―競技会における医療体制向上と重症事故発生予防を目的とした安全度評価法の活用査読あり

田島卓也、帖佐悦男、山本惠太郎、中村嘉宏、山口奈美、柏木輝行

日本整形外科スポーツ医学会雑誌 32 ( 2 ) 35 - 40 2012年5月

記述言語：日本語掲載種別：研究論文（学術雑誌）

膝複合靭帯修復・再建術症例の検討査読あり

田島卓也、山本惠太郎、石田康行、山口奈美、﨑濱智美、帖佐悦男

Journal of Japanese Orthopaedic Society of Knee, Arthroscopy and Sports Medicine 37 126 - 127 2012年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

膝複合靱帯修復・再建術症例の検討

田島卓也, 山本惠太郎, 石田康行, 山口奈美, 崎濱智美, 帖佐悦男

JOSKAS 37 ( 1 ) 126 - 127 2012年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

Tajima T., Chosa E., Yamamoto K., Yamaguchi N.

Sports Medicine, Arthroscopy, Rehabilitation, Therapy and Technology 4 ( 1 ) 9 2012年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Sports Medicine, Arthroscopy, Rehabilitation, Therapy and Technology

Background: Recent years have seen anterior cruciate ligament (ACL) reconstruction being performed in a broad range of patients, regardless of age, sex and occupation, thanks to great advances in surgical techniques, surgical instruments and basic research. In cases of ACL reconstruction, bone-patellar tendon-bone (BTB) graft or hamstring graft are frequency used. However, potential complications associated with tunnel enlargement due to soft tissue graft such as hamstring were reported. On the other hand, an altered rotational axis resulting in significantly greater translation of the lateral compartment in the single bundle compared with double bundle ACL reconstruction was reported.Method and procedure: A reconstruction procedure was modified for the ACL using a double bundle that is the combination of BTB and gracilis tendon composite autograft. Two tibial and two femoral bone tunnels are used to reconstruct two bundles of ACL; an anteromedial bundle (AMB) and a posterolateral bundle (PLB). The femoral bone tunnels are created just posterior to the resident's ridge. The tibial bone tunnels are created at the center of AM and PL tibial attachment, respectively. BTB is fixed in the AM tunnels produced on the anatomical points of tibia and femur. The gracilis graft is fixed in an anatomical PL tunnel produced. The mean width of BTB is 7 mm, since10 mm graft is sometimes not suitable for patients, especially small Asian people and females. For these patients, 10 mm graft is bigger than one third of patella tendon width.Conclusion: The devised surgical procedure based on a combination of BTB and gracilis autograft is suitable reconstruction method for patients who have small or medium width of patellar tendon such as Asian people and females. This technique is also applicable to revision surgery. © 2012 Tajima et al; licensee BioMed Central Ltd.

DOI： 10.1186/1758-2555-4-9

当科における鏡視下腱板修復術の成績 : 術後1年のMRI像と臨床成績

上腕骨骨頭に発生した軟骨芽細胞腫の1症例

宮元修子, 矢野浩明, 山本惠太郎, 石田康行, 田島卓也, 山口奈美, 崎濱智美, 長澤誠, 帖佐悦男

整形外科と災害外科 60 ( 4 ) 692 - 696 2011年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）

鏡視下腱板修復術々後再断裂例の検討

石田康行, 帖佐悦男, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也, 山口奈美, 崎濱智美, 長澤誠, 川野啓介

整形外科と災害外科 60 ( 3 ) 373 - 377 2011年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）

石田康行, 山本惠太郎, 田島卓也, 山口奈美, 崎濱智美, 帖佐悦男

JOSKAS 36 ( 2 ) 212 - 216 2011年5月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：日本関節鏡・膝・スポーツ整形外科学会

Recently, good clinical outcomes of ARCR are reported. On the other hand, the rate of retear which of massive and large rotator cuff tear with advanced fatty degeneration are high. The purpose of this study is to review the clinical outcome and the postoperative cuff integrity of ARCR in our hospital. We evaluated 65 shoulders (52 male, 13 female), which the range of the age was 30-78 (average : 61.8 years old). The size of tears were 7 small, 15 medium, 32 large and 11 massive. We evaluated the pre and postoperative JOA score, and the postoperative MRI findings, performed 12 months postoperatively. We evaluated the cuff integrity by Sugaya's classification, and the fatty degeneration of ruptured cuff by Goutallier's classification. The average of the postoperative JOA score was 92.2, improved from 59.2. Postoperative JOA score of all size was improved. But, as the size of tear was larger, the postoperative JOA score was lower. Postoperative MRI findings showed that complete repair in 46 shoulders (71%), retear in 19 shoulders (29%). Postoperative JOA score was improved regardless of retear. But JOA score of retear cases was worse than that of complete repair cases. The rate of retear was high of the larger size tears and tears with advanced fatty degeneration. We should review the operative indication and the surgical procedure for the larger tears and the advanced fatty degeneration tears.近年, 鏡視下腱板修復術(ARCR)の良好な成績が報告されているが, 断裂サイズが大きい例, 断裂腱板の脂肪変性が高度な例では再断裂が多いといわれる. 当科で行ったARCRの術後成績,腱板修復状態を検討したので報告する. 2005年9月より重層固定法でARCRを行い,術後1年でMRI評価ができた65肩,男性52肩,女性13肩を対象とした. サイズは小断裂7肩, 中断裂15肩, 大断裂32肩, 広範囲断裂11肩であった. 手術時年齢は30～78歳,平均61.8歳であった. 臨床成績を術前と術後1年時のJOA scoreで評価し, 腱板修復状態を術後1年時MRIでの菅谷の分類で評価した. 断裂腱板の脂肪変性をGoutallierの分類で評価した. サイズ別のJOA scoreは各サイズで術前より術後有意に改善していたが, 術後JOA scoreはサイズが増大するにつれて低下傾向であった. 腱板修復状態はtype1が28肩,type2が11肩,type3が7肩,type4が9肩,type5が10肩であった. 再断裂とされるtype4, 5は全例中29%であった.### 腱板修復状態別のJOA scoreはすべてのtypeで術前より術後有意に改善していたが, 術後JOA scoreは再断裂であるtype4, 5で低下傾向であった. サイズ別でtype4, 5の占める割合は小, 中断裂は0%, 大断裂は31.3%, 広範囲断裂は81,8%であった. 断裂腱板脂肪変性別でのtype4, 5の占める割合はgrade0, grade1は0%, grade2は23.1%, grade3は39.1%, grade4は87.5%であった.### 我々の鏡視下重層固定法の成績は諸家の報告と同等であったがサイズが大きい例, 断裂腱板脂肪変性が進んだ例で再断裂率が高かった.### 再断裂率を低下させるために, 手術手技や後療法の工夫が行われている. しかし, 腱板の質が不良な例では手技や後療法を工夫しても再断裂は生じ,一次修復の限界である. 患者の活動性を考慮し保存療法を見直し,手術適応を再検討していきたい. また,腱板の質が不良な例で手術が必要な場合は一次修復にこだわらず, patch法, 部分修復, debridement, 筋移行といった手術法を患者の活動性を考慮し選択していく方針である.

膝前十字靭帯再再建術症例の検討

田島卓也, 山本惠太郎, 石田康行, 山口奈美, 崎濱智美, 帖佐悦男

JOSKAS 36 ( 2 ) 258 - 263 2011年5月

記述言語：日本語掲載種別：研究論文（学術雑誌）

上腕骨骨頭に発生した軟骨芽細胞腫の１症例

宮元修子, 矢野浩明, 山本惠太郎, 石田康行, 田島卓也, 山口奈美, 崎濱智美, 長澤誠, 帖佐悦男

整形外科と災害外科 60 ( 4 ) 692 - 696 2011年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

軟骨芽細胞腫は10歳代の長管骨骨端部に好発する比較的稀な腫瘍である．今回我々は軟骨芽細胞腫の1症例を経験したので文献的考察を加え報告する．症例は15歳女性，右肩を壁に打ちつけ，右肩痛・可動域制限が出現した．その後，右肩挙上困難が出現したため近医受診し，レントゲンで上腕骨頚部に仮骨を認めたため，骨折の診断でリハビリを施行されていた．数か月後，右肩の腫脹に気づいたが放置していた．右背部の外傷あり，その際のレントゲンにて上腕骨に骨透亮像認めたため，MRI施行したところ骨腫瘍疑われ，当科紹介初診となった．生検術を施行し，軟骨芽細胞腫の診断となり，骨腫瘍掻爬と人工骨移植術を施行した．術後3年の最終経過観察時，再発なく右肩可動域制限もない．

DOI： 10.5035/nishiseisai.60.692

鏡視下腱板修復術々後再断裂例の検討

石田康行, 川野啓介, 帖佐悦男, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也, 山口奈美, 崎濱智美, 長澤誠

整形外科と災害外科 60 ( 3 ) 373 - 377 2011年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

鏡視下腱板修復術（ARCR）の良好な成績が報告されているが再断裂例も存在する．ARCRの再断裂率，再断裂に関わる因子，臨床成績，再断裂MRIの検討を行ったので報告する．当科でARCRを行い，調査可能であった80肩，男性61肩，女性19肩を対象とした．年齢は30～78歳であった．臨床成績を術後1年時のJOA score，再断裂の有無を術後1年時MRIで評価した．全例中30％に再断裂を認め，断裂が大きい例，術前腱板脂肪変性が進んだ例，肩甲下筋断裂合併例で再断裂率が高かった．臨床成績は再断裂なし群が術後平均93.9点，再断裂あり群が術後平均87.2点であった．再断裂例を菅谷分類type 4，5に分けるとtype 4がtype 5に比べ有意に術後JOA scoreが改善していた．本術式は置換術ではないので残存腱板の状態が重要である．手術適応，手技についてさらなる検討が必要である．

DOI： 10.5035/nishiseisai.60.373

変形性肘関節症に対する鏡視下手術の治療経験

崎浜智美, 石田康行, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也, 山口奈美, 深尾悠, 河野雅充, 帖佐悦男

整形外科と災害外科 59 ( 3 ) 533 - 535 2010年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）

宮崎県高校女子バスケットボール国体候補選手10名に対するメディカルチェック : 3年間の調査結果と問題点

山口奈美, 山本惠太郎, 石田康行, 河原勝博, 田島卓也, 帖佐悦男, 田島直也

日本整形外科スポーツ医学会雑誌 = Japanese journal of orthopaedic sports medicine 30 ( 2 ) 79 - 86 2010年5月

記述言語：日本語掲載種別：研究論文（学術雑誌）

肩関節過外転で生じた bony PASTA lesion の1例

石田康行, 帖佐悦男, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也, 山口奈美, 崎濱智美

JOSKAS 35 ( 3 ) 468 - 471 2010年5月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：日本関節鏡・膝・スポーツ整形外科学会

Partial-thickness articular-side tears of the rotator cuff were termed "partial articular surface tendon avulsion" (PASTA) by Snyder et al. Avulsion fracture of the medial aspect of the greater tuberosity in the region of the supraspinatus footprint was termed "bony PASTA lesion" by Bhatia et al. Kaspar et al. described a case of hyperabduction injury to the shoulder with fracture and extensive cavitary bone defect in the superolateral proximal humerus, caused by impression of the acromion.### We describe a case of bony PASTA lesion caused by hyperabduction injury to the shoulder. A 41-year-old male fell from a scaffold and hung from it. At that time, his left shoulder was placed in hyperabduction, causing a bony PASTA lesion. Because the displacement of the fragment was slight, he was given only conservative therapy for 7 months. He came to our hospital because motion pain and impingement in his left shoulder were not improved after 7 months. Physical examination revealed impingement sign and motion pain in his left shoulder. Radiographic examination revealed a 10 mm diameter cavitary bone defect and a small bone fragment of his injured greater tuberosity.### We diagnosed impingement syndrome caused by the small bone fragment, and performed arthroscopic operation. The bone fragment was removed, and the PASTA lesion was repaired with arthroscopic transtendon repair technique which preserved the superficial layer of the rotator cuff (arthroscopic PASTA repair). His postoperative course was good, and the preoperative symptoms disappeared.### In such cases, arthroscopic operation is best, because it is less invasive.2004年Kasparらは肩関節過外転による肩峰と上腕骨の衝突で上腕骨近位に骨欠損と骨折を生じる症例があると報告し,2007年Bhatiaらは肩関節前方脱臼後に生じた棘上筋腱大結節付着部関節面側裂離骨折をbony PASTA lesionと称した. 今回,肩関節過外転で生じたbony PASTA lesionの症例を経験したので報告する. 症例は41歳,男性で建築作業中,足場より転落し左手でぶら下がり左肩関節過外転となり,左棘上筋腱大結節付着部関節面側裂離骨折を受傷した. 転位が軽度であったため近医にて保存的加療を行った. 左肩関節運動時痛,ひっかかり感が改善しないため受傷後7カ月で当科紹介受診となった. 画像所見上,上腕骨大結節に直径約10mmの骨欠損像と棘上筋腱大結節付着部関節面側に2×2×5mm大の小骨片を認め,小骨片による肩インピンジメント症候群と考え鏡視下手術を施行した. 小骨片は切除し,棘上筋腱関節面部分断裂を残存腱板を温存し,鏡視下に経腱板的に修復した(arthroscopic PASTA repair). 術後経過良好で術前の症状は消失した. 本例に対する鏡視下手術は鏡視による低侵襲での病変部の評価と残存組織を温存した修復が可能で最良の方法であった.

棘窩切痕部ガングリオンに対する肩峰下滑液包からの鏡視下除圧術の短期成績

石田康行, 帖佐悦男, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也, 山口奈美, 崎濱智美

JOSKAS 35 ( 2 ) 338 - 341 2010年5月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：日本関節鏡・膝・スポーツ整形外科学会

Background : Arthroscopic decompression of a spinoglenoid notch ganglion cyst causing suprascapular nerve palsy is generally performed from the glenohumeral joint (GHJ). However, in some patients, a ganglion is located far from the glenoid, and decompression from the GHJ is difficult. We perform decompression from the subacromial bursa (SAB).### Purpose : We review clinical results of arthroscopic decompression of spinoglenoid notch ganglion cysts from the SAB.### Method : We reviewed 4 shoulders in which we performed arthroscopic decompression of spinoglenoid notch ganglion cysts from the SAB. The patients were 3 males and 1 female. The mean follow-up period was 17.8 months range : 8-33 months. Their mean age was 43.5 years (range : 36-56 years). Preoperative symptoms were shoulder pain in 2 shoulders, muscle weakness in external rotation in 1 shoulder, and both in 1 shoulder. In 1 shoulder we performed decompression from the SAB because we could not do it from the GHJ. In 1 shoulder we performed decompression from both the GHJ and the SAB, because of multilocular cysts. In 2 shoulders we performed decompression from the SAB only. Also in 1 shoulder we added arthroscopic SLAP repair.### Result: One year postoperatively, all cases had improved from their preoperative symptoms, and there were no recurrences observed on MRI.### Discussion : The safety zone for decompressing the course of the suprascapular nerve from the GHJ is said to be 1 cm from the glenoid at the level of the scapular spine. Approaching from the SAB allows safer decompression at a location further from the suprascapular nerve. If a ganglion is multilocular, decompression from both the GHJ and the SAB are also performed to prevent recurrence.【目的】肩甲上神経麻痺を呈する棘窩切痕部ガングリオンに対する鏡視下除圧術は肩甲上腕関節(GHJ)からの除圧が主流であった. しかし,GHJから除圧が困難な症例を時に経験する. 我々はGHJからの除圧が困難な症例や多房性の症例には肩峰下滑液包(SAB)からの除圧術を行っている. 同法を紹介し成績を評価する. ###【対象と方法】2006年5月より棘窩切痕部ガングリオンに対して鏡視下除圧術を行った4肩,男性3肩,女性1肩を対象とした. 年齢は36～56歳. 平均43.5歳. 経過観察期間は8～33カ月,平均17.8カ月. 発生部位は棘上窩1肩,棘上窩2肩,棘上窩から棘下窩1肩であった. 主訴は肩痛が2肩,外旋筋力低下が1肩,肩痛と外旋筋力低下が1肩であった. 除圧は全例鏡視下に行い,GHJから行ったが除圧できずSABから行ったのが1肩,多房性でGHJとSAB双方から行ったのが1肩,SAB単独で行ったのが2肩であった. 1例に関節唇修復を追加した. ###【結果】全例,術前の症状は改善し,経過観察時のMRIで再発を認めていない. ###【考察】肩甲上神経の走行からGHJから除圧する場合のsafety zoneは肩甲棘レベルで関節窩から1cmといわれている. ガングリオンが関節窩の近位に存在する場合,GHJからと比べてSABからの除圧は神経損傷の危険性が少なくなる. また,多房性の場合SABからの除圧はGHJからと併用すれば再発の危険性も少なくなる. SABからの除圧は肩甲上神経より離れた部位での除圧が可能でより安全である.

膝複合靱帯損傷例における後十字靱帯治療法の検討

深尾悠, 山本惠太郎, 矢野浩明, 河原勝博, 石田康行, 田島卓也, 山口奈美, 崎〓智美, 山口志保子, 帖佐悦男

整形外科と災害外科 59 ( 1 ) 178 - 182 2010年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

宮崎県少年選手におけるメディカルチェック : 障害・外傷と関節弛緩性・筋柔軟性との関連について

河原勝博, 帖佐悦男, 山本惠太郎, 田島卓也, 園田典生, 田島直也

日本臨床スポーツ医学会誌 = The journal of Japanese Society of Clinical Sports Medicine 18 ( 1 ) 59 - 66 2010年1月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：日本臨床スポーツ医学会

変形性肘関節症に対する鏡視下手術の治療経験

崎浜智美, 石田康行, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也, 山口奈美, 深尾悠, 河野雅充, 帖佐悦男

整形外科と災害外科 59 ( 3 ) 533 - 535 2010年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

我々は疼痛や可動域制限を有する変形性肘関節症に対して関節鏡視下関節形成術を行なっている．今回，その短期成績を報告する．症例は変形性肘関節症に対し肘関節鏡を施行し術後4ヶ月以上経過観察可能であった5例5肘で男性5肘を対象とした．手術時平均年齢は54.0歳，平均経過観察期間は14.2ヶ月であった．評価方法として，術前後の日本整形外科学会肘機能評価法（JOAスコア）および可動域，合併症の有無で評価した．JOA肘スコアは平均69.0点から91.2点に，可動域は屈曲が平均106.4度から115.6度に，伸展が平均－12.4度から－3.6度と改善が見られたが，術前可動域制限が強い症例での改善度が低い傾向にあった．術後合併症は全例なかった．変形性肘関節症に対する鏡視下手術は組織への侵襲が少なく，有効な手術法であるが，術前可動域制限が強い症例では手術手技の更なる検討が必要である．

DOI： 10.5035/nishiseisai.59.533

膝複合靱帯損傷例における後十字靱帯治療法の検討

深尾悠, 帖佐悦男, 山本惠太郎, 矢野浩明, 河原勝博, 石田康行, 田島卓也, 山口奈美, 崎濱智美, 山口志保子

整形外科と災害外科 59 ( 1 ) 178 - 182 2010年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

膝複合靱帯損傷は交通外傷，転落事故やハイエナジースポーツによって生じ，損傷靱帯の組み合わせや各々の再建方法など治療方針の決定にしばしば難渋することがある．PCL単独損傷例ではしばしば保存的に経過を観察されるが，PCLを含む膝複合靱帯損傷例では近年他の靱帯と同様に手術的に加療される傾向にある．平成17年6月より平成20年7月の間にPCLを含む膝複合靱帯再建術を施行した5例5膝に対し，文献的考察を加え報告する．受傷原因は柔道2例，スキー，交通事故，転落が各1例で，すべて男性であった．平均年齢は29.0歳（17～42歳）であった．損傷靱帯の内訳はACL＋PCL＋MCLが2例，ACL＋PCL，MCL＋PCL，LCL＋PCLが各1例であった．これらの症例に対し，損傷靱帯を同時再建もしくは修復術を行った．PCLの再建材料は全例自家ハムストリング腱を用いた．適応・再建法および術後成績について検討する．

DOI： 10.5035/nishiseisai.59.178

上肢における見過ごされやすいスポーツ外傷・障害

矢野浩明, 帖佐悦男, 山本惠太郎, 石田康行, 河原勝博, 田島卓也, 山口奈美, 崎濱智美

臨床スポーツ医学 = The journal of clinical sports medicine 26 ( 8 ) 975 - 983 2009年8月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：文光堂

前十字靭帯損傷患者のジョギングにおける動作分析 : 関節弛緩性の有無での比較

河原勝博, 帖佐悦男, 鳥取部光司, 山本惠太郎, 田島卓也, 宮崎茂明

運動療法と物理療法 = The Journal of physical medicine 20 ( 2 ) 2009年6月

記述言語：日本語掲載種別：研究論文（学術雑誌）

当科における中高年女性に対する膝前十字靱帯再建術の治療成績

山口志保子, 山本惠太郎, 矢野浩明, 河原勝博, 石田康行, 田島卓也, 三橋龍馬, 帖佐悦男

整形外科と災害外科 58 ( 2 ) 192 - 198 2009年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

当科における中高年女性に対する膝前十字靱帯再建術の治療成績

山口志保子, 山本惠太郎, 矢野浩明, 河原勝博, 石田康行, 田島卓也, 三橋龍馬, 帖佐悦男

整形外科と災害外科 58 ( 2 ) 192 - 198 2009年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

従来は保存的治療を優先された中高年女性のACL損傷例の中で再建を要する症例が増加している．当科における40歳以上の女性のACL再建術の治療成績を検討した．対象は女性43例43膝（右膝16例，左膝27例）で，手術時年齢は14歳～54歳で平均29.8±11.9歳であった．評価項目は受傷原因，術前待機期間，半月損傷合併と関節症性変化（以下OA）の有無，術前と術後12ケ月経過時のJOA score，膝関節可動域，膝関節伸展・屈曲筋力の健患側比について評価し検討した．術前待機期間は年齢と比例して延長していた．手術時に40歳以上の58％に半月損傷合併を認めた．JOA score，関節可動域の年齢差は認めなかった．膝屈曲筋力の健患側比は40歳以上で低下する傾向がみられた．中高年女性のACL再建の治療成績は良好であるが，術前待機期間の長期化を認め半月損傷合併を伴いやすく，術後の膝屈曲筋力の低下傾向がみられた．

DOI： 10.5035/nishiseisai.58.192

Paralabral cyst に対する肩峰下滑液包からの鏡視下除圧術の経験

石田康行, 帖佐悦男, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也

関節鏡 33 ( 3 ) 2008年10月

記述言語：日本語掲載種別：研究論文（学術雑誌）

九州地方にて開催されたラグビー競技会に対する安全度評価

田島卓也, 帖佐悦男, 山本恵太郎, 河原勝博, 中村嘉宏, 吉川大輔, 吉川教恵, 柏木輝行, 東原潤一郎

日本臨床スポーツ医学会誌 = The journal of Japanese Society of Clinical Sports Medicine 16 ( 3 ) 402 - 407 2008年8月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：日本臨床スポーツ医学会

鏡視下骨性バンカート修復術

石田康行, 帖佐悦男, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也

整形外科と災害外科 57 2008年5月

記述言語：日本語掲載種別：研究論文（学術雑誌）

手術適応別の鏡視下腱板修復術の成績

石田康行, 帖佐悦男, 矢野浩明, 山本恵太郎, 河原勝博, 田島卓也

関節鏡 33 ( 2 ) 153 - 158 2008年4月

記述言語：日本語掲載種別：研究論文（学術雑誌）

鏡視下腱板修復術後に生じた肩鎖関節ガングリオンの1例

崎浜智美, 石田康行, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也, 菅田耕, 帖佐悦男

整形外科と災害外科 57 ( 1 ) 162 - 166 2008年3月

記述言語：日本語掲載種別：研究論文（学術雑誌）

鏡視下腱板修復術後に生じた肩鎖関節ガングリオンの１例

崎浜智美, 石田康行, 矢野浩明, 山本惠太郎, 河原勝博, 田島卓也, 菅田耕, 帖佐悦男

整形外科と災害外科 57 ( 1 ) 162 - 166 2008年

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

【はじめに】鏡視下腱板修復術後に生じた肩鎖関節ガングリオンの症例を経験したので報告する．【症例】62歳，女性．平成17年4月転倒し右肩腱板広範囲断裂受傷．保存的加療するも右肩痛改善しないため，平成17年10月鏡視下腱板修復術施行した．術後右肩痛改善するも術後7ヶ月，右肩鎖関節痛と同部位に腫瘤出現した．MRIにて肩鎖関節直上にT1 low，T2 highの多房性の腫瘤認め，肩峰下滑液包造影で肩峰下滑液包から肩鎖関節，腫瘤へと造影剤の流出を認めた．肩鎖関節ガングリオンの診断で，平成18年11月肩関節鏡，ガングリオン切除，鎖骨遠位端切除術施行した．術後肩鎖関節痛，ガングリオン再発なく経過している．

DOI： 10.5035/nishiseisai.57.162

肩関節脱臼後に腋窩神経麻痺を伴った腱板広範囲断裂の治療経験

石田康行, 帖佐悦男, 矢野浩明, 山本恵太郎, 河原勝博, 田島卓也, 小牧ゆか, 樋口誠二, 酒井健, 海田博志

整形外科と災害外科 56 ( 4 ) 525 - 528 2007年9月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：西日本整形・災害外科学会

【目的】神経麻痺を伴った腱板断裂の治療法は見解が分かれる．我々は肩関節脱臼後に腋窩神経麻痺を伴った腱板広範囲断裂2例に対し鏡視下腱板修復術を行い良好な成績を得たので報告する．【症例1】60歳，男性．転倒し右肩関節受傷．右肩自力挙上困難にて受傷後6週で初診．右三角筋に筋萎縮，右肩外側に痺れ感を認めた．受傷後3ヶ月で鏡視下腱板修復術施行した．JOA scoreは術前31点が術後1年で94点に改善した．【症例2】47歳，男性．転倒し右肩関節受傷．右肩自力挙上困難にて受傷後3週で初診．右三角筋の筋萎縮，右肩外側に痺れ感を認め，EMGにて右三角筋に安静時脱神経電位を認めた．受傷後1ヶ月で鏡視下腱板修復術を施行した．JOA scoreは術前45点が術後6ヶ月で93点に改善した．【考察】腱板の変性を考えると断裂が大きい場合は神経の回復傾向がみられたら早期に手術を考慮していいのではと考える．

DOI： 10.5035/nishiseisai.56.525

Hemoglobin stimulates the expression of matrix metalloproteinases, MMP-2 and MMP-9 by synovial cells: A possible cause of joint damage after intra-articular hemorrhage

Tajima T., Yoshida E., Yamashita A., Ohmura S., Tomitaka Y., Sugiki M., Asada Y., Maruyama M.

Journal of Orthopaedic Research 23 ( 4 ) 891 - 898 2005年7月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Journal of Orthopaedic Research

Intra-articular bleeding causes degradation of articular cartilage leading to joint disorders, but the mechanisms is not well understood. The present study examined the effect of hemoglobin on the ability of synovial tissues to produce plasminogen activators and matrix metalloproteinases that play important roles in the degradation of articular cartilage. Human Hb added to primary cultures of human knee synovial cells markedly increased fibrinolytic activity and gelatinolytic activity. The fibrinolytic activity was due to an increase in uPA activity. Western blot analysis and gelatin zymography indicated that the increased gelatinolytic activity was due to increased MMP-2 and -9. In order to know whether the effect of Hb on cultured synovial tissue is also true in in vivo system or not, rabbit hemoglobin was injected into rabbit knee joints. Coinciding with in vitro study, hemoglobin elicited considerable increase in fibrinolytic and gelatinolytic activity. The level of proteoglycan fragments in the hemoglobin-treated joint fluid was significantly elevated, indicating cartilage matrix degradation. Cartilage damage after hemoglobin treatment was also confirmed by histological study. These findings suggest that hemoglobin stimulates the secretion of uPA, MMP-2 and MMP-9 by synovial tissues, and raise a possible role of hemoglobin in joint damage after intra-articular bleeding. © 2005 Published by Elsevier Ltd. on behalf of Orthopaedic Research Society.

DOI： 10.1016/j.orthres.2005.01.003