脇谷 晶一 (ワキタニ ショウイチ)

WAKITANI Shoichi

写真a

所属

農学部 獣医学科

職名

准教授

外部リンク

学位 【 表示 / 非表示

  • 博士(獣医学) ( 2011年9月   山口大学 )

 

論文 【 表示 / 非表示

  • Anatomical View of the Internal Carotid Artery Occlusion in Japanese Black Cattle 査読あり

    Jadi A.R., Fujisaki H., Ramah A., Baakhtari M., Imatake S., Wakitani S., Yasuda M.

    Animals   14 ( 3 )   2024年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Animals  

    The internal carotid artery (ICA) is a branch of the common carotid artery (CCA), along with the external carotid artery (ECA), which together provide the blood supply for the brain. The description of the ICA in cattle is vague, including denial of its existence or degeneration at an early stage after birth. This anatomical study investigated the internal carotid artery in Japanese black cattle. Sixty-five heads of Japanese black cattle aged from newborn to 13 years were dissected and injected with colored latex from the CCA after separating the head and body. Diameter measurements of the artery branches from the CCA on its bifurcation were conducted. Furthermore, a histological examination of the ICA wall’s structures, which consist of the tunica intima, tunica media, and tunica externa, was performed. The ICA of Japanese black cattle is closed on the left side after age 3 years, except for a small lumen at 13 years, whereas the right ICA remains open at all ages. The location of occlusion of the left internal carotid artery (LICA) shows thickness of the tunica intima and an increased connective tissue layer area. The diameter of the ICA does not differ between the left and right sides, and there is no correlation with age. Therefore, further studies are needed, especially of ICA occlusion related to Japanese black cattle’s physiology or cerebrospinal disease.

    DOI: 10.3390/ani14030365

    Scopus

    PubMed

  • Naturally occurring phytanic acid exerts anti-inflammatory effects in a mouse model of dextran sulfate sodium-induced colitis 査読あり

    Nakanishi T., Suga K., Wakitani S., Yamaguchi K., Sugamoto K., Erickson L., Kawahara S.

    European Journal of Lipid Science and Technology   2024年

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:European Journal of Lipid Science and Technology  

    Phytanic acid is one of the branched-chain fatty acids in the human diet. Humans incorporate it into their bodies through the ingestion of ruminant meat and milk since these animal products contain the 3RS, 7R, 11R-isomer, as naturally occurring phytanic acid (nPA). Although phytanic acid has been reported to have health-promoting effects such as immunomodulatory effects, these findings were obtained mostly from in vitro cell-based experiments. In this study, the in vivo anti-inflammatory effects of nPA were investigated using a mouse model of dextran sulfate sodium (DSS)-induced colitis. Mice were fed diets containing 0%, 0.05%, or 0.1% nPA for 4 weeks. During the fourth week, acute colitis was induced by administration of a 3% DSS solution. The intake of 0.05% and 0.1% nPA inhibited DSS-induced body weight loss in mice, and showed improvement of histopathological changes in colon epithelium. nPA also inhibited the production of proinflammatory cytokines, especially macrophage-related cytokines such as interleukin-1β in the colon. These results suggest that nPA exerts anti-inflammatory effects under in vivo physiological conditions. Practical application: There is a growing demand for fatty acids possessing distinct nutritional and physical characteristics in the realms of health, nutrition, and food-related applications. The present study demonstrated that a branched-chain fatty acid, phytanic acid, exerts anti-inflammatory activity under not only in vitro but also in vivo conditions, using a commonly used mouse model of human inflammatory bowel disease. Our findings encourage further studies to determine whether phytanic acid elicits beneficial properties in humans, and suggest that phytanic acid enrichment can be a novel product strategy in the food market.

    DOI: 10.1002/ejlt.202300165

    Scopus

  • Use of platelet lysate for in-vitro embryo production and treatment of repeat breeding in cows 査読あり

    Hassaneen A.S.A., Rawy M.S., Yamanokuchi E., Elgendy O., Kawano T., Wakitani S., Kitahara G., Osawa T.

    Theriogenology   210   199 - 206   2023年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Theriogenology  

    Platelet-rich plasma (PRP) is a biological hemocomponent derived from blood after the complete removal of red blood cells and the partial or complete removal of white blood cells to concentrate platelets in an appropriate volume of plasma. Platelets have important growth factors, cytokines, and active metabolites that improve the endometrial environment and positively affect implantation. This study evaluated the effect of the addition of activated PRP (platelets lysate; PL) on in vitro bovine oocyte maturation and embryonic development and the effect of intrauterine (IU) infusion of autologous PL in repeat breeder (RB) cows. Experiment 1 examined the effects of allogeneic PL, fetal calf serum (FCS), mixed PL + FCS, or platelet-poor plasma (PPP) supplementations to in vitro maturation and development media on in vitro oocyte maturation and embryo development in good- and poor-quality oocytes of Japanese Black cows. Experiment 2 examined the IU infusion of autologous PL, 24 h post-insemination, in 21 RB Holstein-Friesian dairy cows. The cleavage rate of good-quality oocytes was higher in the PL group (85.93 ± 2.50%) than in the PPP group (67.16 ± 3.41%) (P < 0.05), while the cleavage rate of the poor-quality oocytes was higher in the PL alone (76.13 ± 4.04%) and mixed PL + FCS treated (73.59 ± 4.22%) groups than in the PPP group (54.64 ± 2.93%) (P < 0.05). The blastocyst rate of the good-quality oocytes was higher in the PL group (40.97 ± 3.03%) than in the FCS (27.97 ± 3.31%) and PPP (25.33 ± 2.15%) groups (P < 0.05). The blastocyst rate of poor-quality oocytes and the hatching rates of both good and poor-quality oocytes showed no significant differences among all groups. The conception rate in the autologous PL-treated group was 41.67% (5/12), while it was 11.11% (1/9) in the control group. The platelets' count in the pregnant PL-treated cows (n = 5; mean ± SEM, 1.07 ± 0.10 × 109/mL) was higher than in the non-pregnant ones (n = 7; 0.67 ± 0.10 × 109/mL) (P < 0.05). In conclusion, allogeneic PL was effective in stimulating the in vitro oocyte maturation and embryonic development in both good and poor-quality bovine oocytes, and post-insemination IU infusion of autologous PL derived from high platelets’ count-PRP would be recommended for the treatment of RB cows.

    DOI: 10.1016/j.theriogenology.2023.07.034

    Scopus

    PubMed

  • Prevalence of anatomic variants in coronary arteries of Japanese Black cattle 査読あり

    Ohashi Y., Wakitani S., Yasuda M.

    Journal of Veterinary Medical Science   85 ( 2 )   135 - 142   2023年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Veterinary Medical Science  

    Coronary artery anomalies that can cause sudden cardiac death have been described in some mammals. However, few studies have investigated coronary anomalies and coronary artery branching patterns in cattle. Therefore, understanding of bovine coronary arteries is incomplete. The aim of this study was to clarify anatomic variants in coronary arteries of Japanese Black cattle. The gross anatomy of the coronary arteries was examined in the hearts of 100 cattle. A total of 14 of 100 hearts exhibited confirmed coronary anomalies in the left main trunk. These 14 hearts were classified into 5 types potentially associated with cardiac ischemia. Regarding the coronary branches, the subsinuosal interventricular branch originated from the left circumflex branch (LCX) in 98 hearts and from the right coronary artery in 2 hearts. The origin of the sinoatrial nodal branch was classified into 3 types. In 99 hearts, the atrioventricular nodal branch originated from the LCX at the heart crux. This study characterized the prevalence of coronary anomalies, branching patterns of coronary arteries, and coronary artery anatomic variants in Japanese Black cattle.

    DOI: 10.1292/jvms.22-0369

    Scopus

    PubMed

    CiNii Research

  • Feeding ecology of Swinhoe’s tree lizard (Diploderma swinhonis (Günther, 1864)) in Hyuga City, Miyazaki Prefecture, Japan 査読あり

    Tanaka M., Imatake S., Takeshita H., Wakitani S., Yasuda M.

    Journal of Veterinary Medical Science   84 ( 12 )   1610 - 1616   2022年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Journal of Veterinary Medical Science  

    Swinhoe’s tree lizard (Diploderma swinhonis: D. swinhonis) is an arboreal agamid that is native to Taiwan. In Taiwan, the lizard is considered to be a generalist that feeds primarily on ants and a diversity of small insect prey by employing an opportunistic sit-and-wait foraging strategy. In Japan, D. swinhonis is considered as an invasive alien species that was discovered in Hyuga city, Miyazaki Prefecture, in 2016. Despite concerns about the impact of D. swinhonis on native fauna, little information about the diet of this alien species has been published to date. This study, therefore, investigated the feeding ecology of D. swinhonis in Hyuga city to evaluate their potential impact on the ecosystem. Specifically, prey preference was investigated by examining the stomach contents of males, females, and juveniles captured from April to December 2020 and in March 2021. The results showed that the lizards in Hyuga preyed upon a wide variety of invertebrates as in Taiwan, while ants accounted for the largest proportion of the prey items consumed regardless of sex, age or changes in season. These findings indicated that D. swinhonis might cause a decrease in the abundance of the native insect fauna of Hyuga city or competition with native lizards for foods in Hyuga city. Since its impact is not currently apparent, it’s necessary to monitor its effect in the future.

    DOI: 10.1292/jvms.22-0153

    Scopus

    PubMed

    CiNii Research

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書籍等出版物 【 表示 / 非表示

  • 獣医組織学 第8版

    日本獣医解剖学会( 担当: 分担執筆 ,  範囲: 第14章 心臓血管系)

    学窓社  2020年3月 

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    担当ページ:141-153   記述言語:日本語 著書種別:教科書・概説・概論

  • 平成31年度・令和元年度畜産生産に関する研究調査成果報告書

    脇谷 晶一, 保田 昌宏( 担当: 共著)

    一般財団法人 畜産ニューテック協会  2020年 

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    記述言語:日本語 著書種別:調査報告書

  • 獣医発生学 第2版

    T. A. McGeady, P. J. Quinn, E. S. Fitzpatrick, M. T. Ryan, D. Kilroy, P. Lonergan( 担当: 共訳 ,  範囲: 第14章 心臓血管系)

    学窓社  2019年2月 

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    担当ページ:141-153   記述言語:日本語 著書種別:教科書・概説・概論

  • 平成29年度食肉に関する助成研究調査成果報告書

    脇谷 晶一, 保田 昌宏( 担当: 共著)

    公益財団法人 伊藤記念財団  2018年11月 

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    記述言語:日本語 著書種別:調査報告書

MISC 【 表示 / 非表示

  • TGF-β superfamily signaling in testis formation and early male germline development

    Julia C. Young, Shoichi Wakitani, Kate L. Loveland

    Seminars in Cell & Developmental Biology   2015年10月

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    記述言語:英語   掲載種別:記事・総説・解説・論説等(学術雑誌)   出版者・発行元:Elsevier Ltd.  

講演・口頭発表等 【 表示 / 非表示

  • スウィンホーキノボリトカゲの性決定様式および孵卵温度による性比の変化

    今竹翔一朗,佐藤暢,脇谷晶一,保田昌宏

    第29回日本野生動物医学会大会 

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    開催年月日: 2023年9月22日 - 2023年9月24日

    記述言語:日本語   会議種別:口頭発表(一般)  

  • 黒毛和種廃用子牛の胸腺の病理組織学的異常度と胸腺トランスクリプトームの関連

    古川 涼悟、脇谷 晶一、川端 理紗子、保田 昌宏

    第166回日本獣医学会学術集会 

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    開催年月日: 2023年9月5日 - 2023年9月8日

    記述言語:日本語   会議種別:口頭発表(一般)  

  • 野鳥における前翼膜靭帯の比較解剖

    深沢 英恵、杉山 真言、進藤 順治、脇谷 晶一、吉岡 一機

    第166回日本獣医学会学術集会 

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    開催年月日: 2023年9月5日 - 2023年9月8日

    記述言語:日本語   会議種別:口頭発表(一般)  

  • 新規骨軟骨染色法(JFRL 染色)の医療機器生物学的安全性試験への応用

    辻絵里香,鷲見嘉奈子,中村鉄平,近藤大輔,辻尾祐志,細谷実里奈,難波貴志, 脇谷晶一,市居 修,西野光一郎,昆 泰寛,三嶋 隆,吉安友二,勝田真一

    第44回日本バイオマテリアル学会大会  2022年11月22日 

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    開催年月日: 2022年11月21日 - 2022年11月22日

    記述言語:日本語   会議種別:ポスター発表  

  • Diploderma 属のトカゲ 2 種の皮膚色素胞の配置と超微細構造

    岡 亮太朗、脇谷 晶一、今竹 翔一朗、保田 昌宏

    第28回日本野生動物医学会大会  2022年9月23日 

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    開催年月日: 2022年9月22日 - 2022年9月24日

    記述言語:日本語   会議種別:口頭発表(一般)  

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科研費(文科省・学振・厚労省)獲得実績 【 表示 / 非表示

  • 虚弱子牛症候群の低免疫状態に関与する胸腺皮質上皮細胞の特性解析

    研究課題/領域番号:22K05988  2022年04月 - 2025年03月

    独立行政法人日本学術振興会  科学研究費補助金  基盤研究(C)

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    担当区分:研究代表者 

  • ヒトiPS細胞のFGF依存性機構の解明:Nodalシグナリングの多重制御

    研究課題/領域番号:16K21243  2016年04月 - 2018年03月

    独立行政法人日本学術振興会  科学研究費補助金  若手研究(B)

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    担当区分:研究代表者 

    ヒトiPS細胞のFGF依存性機構の解明:Nodalシグナリングの多重制御