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Faculty of Medicine School of Medicine Department of Medicine of Pathophysiological Diagnosis and Therapy, Emergency, Critical Care, and Disaster Medicine |
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OCHIAI Hidenobu
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Degree 【 display / non-display 】
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Ph.D (Medicine) ( 2005.3 University of Miyazaki )
Papers 【 display / non-display 】
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投稿 症例 細菌性髄膜炎の経過中に低カリウム血症を契機にBrugada症候群様の心電図異常を呈し,心室細動をきたした1例 Reviewed
法化図 陽一, 中平 孝明, 日髙 颯之介, 北條 健人, 落合 秀信
内科 135 ( 6 ) 1397 - 1400 2025.6
Publishing type：Research paper (scientific journal) Publisher：南江堂
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What should acute care surgery be like in regional facilities? Reviewed
Kawano Fumiaki, Tashiro Kousei, Ikenoue Makoto, Munakata Shun, Suzuki Yasuto, Takeno Shinsuke, Furukawa Kouji, Ochiai Hidenobu, Nanashima Atsushi
Japanese Journal of Acute Care Surgery advpub ( 0 ) 2025.4
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japanese Society for the Acute Care Surgery
We looked back on the 10 years of acute care surgery 〈ACS） at our department and discussed what type of ACS is required in facilities in regional cities. In our department, the emergency and critical care unit started in 2012, which required major changes in the surgical emergency treatment system. At the regional level, we focused on maintaining the existing emergency system, and we established a system in which severe injuries and trauma cases were concentrated in our department. At the facility level, ACS team was formed with existing surgeons to facilitate trauma care and actively intervene in trauma care. In addition, to maintain the team, we improved the on-call system and implemented complete division of labor in perioperative management. At the individual level, we performed daily surgical tasks with a specialty to maintain surgical skills and motivation. In addition, we made efforts to encourage young surgeons and residents to intervene in the practice in order to foster the Acute care surgeons. In this way, we believe that ACS in regional cities can be established by maintaining the existing emergency system and having existing surgeons create a system that is suited to the facilities.
DOI： 10.50840/jjacs.15-1
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Tanohata Rina, Saito Katsutoshi, Nagano Takehiko, Ochiai Hidenobu
Journal of Rural Medicine 20 ( 2 ) 125 - 131 2025.4
Language：English Publishing type：Research paper (scientific journal) Publisher：THE JAPANESE ASSOCIATION OF RURAL MEDICINE
DOI： 10.2185/jrm.2024-053
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Saito Katsutoshi, Abe Tomohiro, Tanohata Rina, Nagano Takehiko, Ochiai Hidenobu
Journal of Rural Medicine 20 ( 2 ) 92 - 101 2025.4
Language：English Publishing type：Research paper (scientific journal) Publisher：THE JAPANESE ASSOCIATION OF RURAL MEDICINE
DOI： 10.2185/jrm.2024-038
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Abe T., Saito K., Nagano T., Yamada Y., Ochiai H.
Thrombosis Research 247 109281 2025.3
Language：English Publishing type：Research paper (scientific journal) Publisher：Thrombosis Research
Background: Sepsis-induced disseminated intravascular coagulation (DIC) increases mortality in sepsis patients. Complement system activation is concomitant with sepsis-induced DIC; however, it is unclear how these two pathologies influence clinical parameters of sepsis individually and in combination, and which of the complement pathways activation is predominantly associated with mortality. Methods: In this ancillary analysis of a prospective observational study, 49 adult sepsis patients were assigned to four groups according to the absence/presence of DIC and complement activation. Effects of complement activation and DIC on clinical demographics including parameters of DIC, systemic severities, and 60-days all-cause mortality were assessed by comparing the groups. We analyzed each complement pathway by comparing Bb, C3a/C3 ratio, SC5b-9/C3 ratio, C4d, C4d/C4 ratio, C3a, C5a, and SC5b-9 between survivors/non-survivors both in all the patients and in the DIC+ subgroup. Results: Complement system activation induced thrombocytopenia and enhanced sepsis severity measured as APACHE2 and SOFA scores. 60-days all-cause mortality was different between groups, with 0 % in the complement activation alone group, 14 % in the DIC alone group and 66 % in the combined DIC and complement activation group. Bb and C3a/C3 and SC5b-9/C3 ratios were higher in non-survivors, with Bb and SC5b-9/C3 ratio still higher in DIC+ non-survivors. Conclusion: Complement activation worsen the severity of sepsis and cause thrombocytopenia. Co-occurrence of complement activation and DIC increased sepsis mortality. The alternative pathway of complement activation plays a major role in sepsis mortality.
Books 【 display / non-display 】
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今日の治療指針2023年版 私はこう治療している
落合 秀信（ Role： Contributor , 【中毒性疾患】塩素ガス中毒）
医学書院 2023.1
Responsible for pages：143-143 Book type：Scholarly book
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今日の治療指針2022年版 私はこう治療している
落合 秀信（ Role： Contributor , 【中毒性疾患】シアン中毒）
医学書院 2022.1
Responsible for pages：143-143 Book type：Scholarly book
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今日の治療指針2021年版 私はこう治療している
落合 秀信（ Role： Contributor , 【中毒性疾患】酸・アルカリ化学損傷）
医学書院 2021.1
Responsible for pages：146-147 Book type：Scholarly book
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今日の治療指針2020年版 私はこう治療している
落合 秀信（ Role： Contributor , 【中毒性疾患】グリホサート・グルホシネート中毒）
医学書院 2020.1
Responsible for pages：134-135 Language：Japanese Book type：Scholarly book
MISC 【 display / non-display 】
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Azuma M., Nakada H., Takei M., Nakamura K., Katsuragawa S., Shinkawa N., Terada T., Masuda R., Hattori Y., Ide T., Kimura A., Shimomura M., Kawano M., Matsumura K., Meiri T., Ochiai H., Hirai T.
Emergency Radiology 29 ( 2 ) 425 2022.4
Language：Japanese Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：Emergency Radiology
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Complement-mediated thrombotic microangiopathy secondary to sepsis-induced disseminated intravascular coagulation successfully treated with eculizumab: A case report.
Abe T, Sasaki A, Ueda T, Miyakawa Y, Ochiai H.
Wolters Kluwer Health 96 ( 6 ) e6056 2017.2
Language：English Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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ノロウイルス性胃腸炎に合併した劇症型Clostridium perfringens感染症の1例 Reviewed
長野健彦, 安部智大, 長嶺育弘, 今井光一, 松岡博史, 金丸勝弘, 落合秀信, 牧原真治, 廣兼民徳
宮崎県医師会医学会誌 40 ( 1 ) 60 - 64 2016.3
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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【E Word 私が大切にしている言葉】及ばざるは過ぎたるよりまされり 平常心
落合秀信
Emergency Care 26 ( 8 ) 1 - 1 2013.7
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media) Publisher：メディカ出版
Presentations 【 display / non-display 】
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地域医療機関と宮崎大学救命救急センターとの連携の過去・現在・未来について
落合秀信
第23回宮崎生協病院地域連携懇談会 (宮崎)
Event date： 2023.3.24
Presentation type：Oral presentation (invited, special)
Venue：宮崎
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宮崎大学における重度四肢外傷治療の実情と今後の課題
日吉優，帖佐悦男，中村嘉宏，今里浩之，平川雄介，山口洋一朗，森田雄大，落合秀信
第57回宮崎救急医学会 (宮崎)
Event date： 2023.3.18
Presentation type：Oral presentation (general)
Venue：宮崎
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宮崎県北部地域精神科救急疾患対応の現状と課題について
長嶺育弘，森久保裕，島津志帆子，岩本和樹，佐藤由佳子，出口ゆかり，木佐貫ゆかり，金丸勝弘，落合秀信
第57回宮崎救急医学会 (宮崎)
Event date： 2023.3.18
Presentation type：Oral presentation (general)
Venue：宮崎
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宮崎県北部地域救急医療体制の変化及び今後の課題について
長嶺育弘，森久保裕，島津志帆子，岩本和樹，木佐貫ゆかり，金丸勝弘，落合秀信
第57回宮崎救急医学会 (宮崎)
Event date： 2023.3.18
Presentation type：Oral presentation (general)
Venue：宮崎
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胃石形成により循環不全が遷延したアムロジピン中毒に対して上部消化管内視鏡を用いて洗浄・胃石除去を施行した1例
畠中健吾, 工藤陽平, 落合秀信
第6回日本臨床・分析中毒学会総会・学術集会 (川崎)
Event date： 2023.3.11
Presentation type：Oral presentation (general)
Venue：川崎