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Affiliation |
Faculty of Medicine College Hospital Mother and child health center of integrated perinatal period |
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NAKAME Kazuhiko
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Degree 【 display / non-display 】
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Doctor of philosophy in Medical Science ( 2017.3 Kagoshima University )
Papers 【 display / non-display 】
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A retrospective analysis of the real-time ultrasound-guided supraclavicular approach for the insertion of a tunneled central venous catheter in pediatric patients. Reviewed International journal
Kazuhiko Nakame, Tatsuru Kaji, Shun Onishi, Masakazu Murakami, Ayaka Nagano, Mayu Matsui, Taichiro Nagai, Keisuke Yano, Toshio Harumatsu, Koji Yamada, Waka Yamada, Ryuta Masuya, Mitsuru Muto, Satoshi Ieiri
The journal of vascular access 11297298211008084 - 11297298211008084 2021
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
PURPOSE: Tunneled central venous catheter (tCVC) placement plays an important role in the management of pediatric patients. We adopted a real-time ultrasound (US)-guided supraclavicular approach to brachiocephalic vein cannulation. We evaluated the outcomes of tCVC placement via a US-guided supraclavicular approach. METHODS: A retrospective study was performed for patients who underwent US-guided central venous catheterization of the internal jugular vein (IJV group) and brachiocephalic vein (BCV group) in our institution. The background information and outcomes were reviewed using medical records. RESULTS: We evaluated 85 tCVC placements (IJV group: n = 59, BCV group: n = 26). Postoperative complications were recognized in 19 patients in the IJV group (catheter-related bloodstream infection (CRBSI), n = 14 (1.53 per 1000 catheter days); occlusion, n = 1 (1.7%, 1.09 per 1000 catheter days); accidental removal, n = 3 (5.2%, 0.33 per 1000 catheter days); and other, n = 1 (1.7%, 1.09 per 1000 catheter days)) and five patients in the BCV group (CRBSI, n = 2 (0.33 per 1000 catheter days); catheter damage, n = 1 (3.8%, 1.67 per 1000 catheter days); and accidental removal, n = 2 (7.7%, 0.33 per 1000 catheter days)). In the BCV group, despite that, the incidence of postoperative complications was lower (p = 0.205) and the period of placement was significantly longer in comparison to the IJV group (p = 0.024). CONCLUSION: US-guided placement of tunneled CVC though the BCV results in a low rate of postoperative complications despite longer CVC indwelling times compared to IJV insertion. Our results suggest that BCV insertion of tunneled CVC in children may offer advantages in terms of device performance and patient safety.
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Iwamoto Y., Onishi S., Sugita K., Nakame K., Kaji T., Yano K., Ogata M., Takada L., Kedoin C., Nagano A., Murakami M., Harumatsu T., Yamada K., Yamada W., Masuya R., Kawano T., Muto M., Ieiri S.
Pediatric Surgery International 40 ( 1 ) 207 2024.12
Language：English Publishing type：Research paper (scientific journal) Publisher：Pediatric Surgery International
Purpose: Ultrasound-guided supraclavicular catheterization (UGSC) of the brachiocephalic vein (BCV) for long-term tunneled central venous catheter (tCVC) insertion may be safer than the internal jugular vein approach due to its superior field of view. We examined the clinical outcomes of tCVC insertions performed by junior residents through UGSC of the BCV. Patients and methods: From January 2018 to December 2023, we assessed clinical outcomes and compared the experience levels of surgeons conducting tCVC insertions. Surgeons were categorized into three groups: junior residency (JR), senior residency (SR), and board-certified pediatric surgeons (BCPS). Results: 177 tCVC insertions were done on 146 patients. Intraoperative complications included 6 cases of arterial puncture, 1 case of pneumothorax, 1 case of over insertion of catheter tip, and 1 case of suspected hemothorax. Distribution across groups was as follows: 28 cases (15.8%) in JR group, 92 (52.0%) in SR group, and 57 (32.2%) in BCPS group. Although the JR group exhibited longer operation times than the BCPS group, no significant differences in intraoperative complications were noted. Conclusion: Junior residents can safely perform UGSC for tCVC insertion. However, careful consideration of complications such as arterial or thoracic puncture is essential and case selection should be based on experience.
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Masuya R., Muraji T., Harumatsu T., Machigashira S., Iwamoto Y., Ogata M., Takada L., Nishida N., Kedoin C., Nagano A., Matsui M., Murakami M., Sugita K., Yano K., Onishi S., Yamada K., Yamada W., Matsukubo M., Kawano T., Muto M., Nakame K., Kaji T., Nanashima A., Ieiri S.
Surgery Today 54 ( 5 ) 452 - 458 2024.5
Language：English Publishing type：Research paper (scientific journal) Publisher：Surgery Today
Purpose: We compared the clinical features of patients with biliary atresia (BA) associated with a bleeding tendency (BT) at the time of the diagnosis with those of patients without a bleeding tendency (NBT). Methods: The patients’ background characteristics, age in days at the first visit, Kasai portoenterostomy (KPE), and postoperative course were retrospectively analyzed. Results: Nine of the 93 BA patients (9.7%) showed a BT, including 7 with intracranial hemorrhaging (ICH), 1 with gastrointestinal bleeding, and 1 with a prothrombin time (PT) of 0%. The age at the first visit was 62 ± 12 days old for BT patients and 53 ± 27 days old for NBT patients (p = 0.4); the age at KPE was 77 ± 9 days old for BT patients and 65 ± 24 days old for NBT patients (p = 0.2); the time from the first visit to surgery was 13 ± 7 days for BT patients and 11 ± 10 days for NBT patients (p = 0.5); and the native liver survival rate was 56% for BT patients and 58% for NBT patients (p = 1), with no significant difference in any of the parameters. The neurological outcomes of survivors of ICH were favorable. Conclusions: Appropriate BT correction allowed early KPE even after ICH, resulting in native liver survival rates comparable to those of NBT patients without significant neurological complications.
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特集 小児領域におけるGLP-2アナログ製剤(テデュグルチド)の応用 総論 GLP-2の基礎研究
矢野 圭輔, 杉田 光士郎, 武藤 充, 大西 峻, 岩元 祐実子, 緒方 将人, 高田 倫, 祁答院 千寛, 村上 雅一, 松久保 眞, 川野 孝文, 中目 和彦, 加治 建, 家入 里志
小児外科 56 ( 4 ) 320 - 325 2024.4
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：東京医学社
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Nakame Kazuhiko, Masuya Ryuta, Nakazawa Shun, Nakagawa Midori, Yamada Ai, Kinoshita Mariko, Kamimura Sachiyo, Moritake Hiroshi, Ieiri Satoshi, Nanashima Atushi
Journal of the Japanese Society of Pediatric Surgeons 60 ( 2 ) 158 - 165 2024.4
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japanese Society of Pediatric Surgeons
<i>Purpose</i>: Central venous catheters (CVCs) are used in the treatment of pediatric hematological and oncological diseases. Recently, the ultrasound (US)-guided supraclavicular approach to brachiocephalic vein cannulation with in-plane views has been described as a safe central venous catheterization technique.<i>Methods</i>: A retrospective study was performed on patients who underwent US-guided tunneled CVC insertion into the internal jugular vein with out-of-plane views (IJV group) and the brachiocephalic vein with in-plane views (BCV group). The patients’ background characteristics, surgical outcomes, and complications were compared retrospectively.<i>Results</i>: A total of 40 tunneled CVCs (IJV group: n = 15, BCV group: n = 25) were inserted in 34 patients. The patients’ background characteristics were not significantly different between the two groups. The operative times were 30 min (range: 27–33 min) in the IJV group and 25.8 min (range: 22–27 min) in the BCV group. The BCV group had a significantly shorter operative time (p = 0.0026). Intraoperative complications were observed in one patient (6.7%) in the IJV group and none of the patients in the BCV group. Complications during maintenance were observed in 10 patients (66.7%) in the IJV group and 17 patients (68%) in the BCV group. Catheter-related bloodstream infection was noted in 10 patients (66.7%) in the IJV group and 12 patients (52%) in the BCV group; these infection rates were not significantly different. The periods of CVC implantation were 273 days (172–363.5 days) in the IJV group and 152 days (101–280 days) in the BCV group, which were not significantly different.<i>Conclusions</i>: A real-time US-guided supraclavicular approach to brachiocephalic catheterization was considered a safe technique for pediatric patients with hematological and oncological diseases.
MISC 【 display / non-display 】
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胃穿孔による汎発性腹膜炎を生じた急性胃軸捻転の1小児例 Reviewed
桝屋 隆太, 中目 和彦, 西牟田 雅人, 長友 謙三, 和田 敬, 甲斐 健吾, 池ノ上 実, 田代 耕盛, 市原 明子, 河野 文彰, 池田 拓人, 武野 慎祐, 七島 篤志
日本腹部救急医学会雑誌 40 ( 2 ) 313 - 313 2020.2
Language：Japanese Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(一社)日本腹部救急医学会
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鹿児島県内の後天性声門下腔狭窄症例発生状況と患者背景からの考察 Reviewed
武藤 充, 連 利博, 永井 太一郎, 大西 峻, 春松 敏夫, 山田 耕嗣, 松久保 眞, 町頭 成郎, 中目 和彦, 向井 基, 加治 建, 家入 里志
日本小児外科学会雑誌 56 ( 1 ) 132 - 132 2020.2
Language：Japanese Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(一社)日本小児外科学会
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声門下嚢胞による反復性クループ様症状を呈した1幼児例 Reviewed
永井 太一朗, 連 利博, 大西 峻, 武藤 充, 中目 和彦, 家入 里志
日本小児科学会雑誌 124 ( 1 ) 91 - 91 2020.1
Language：Japanese Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(公社)日本小児科学会
Presentations 【 display / non-display 】
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呼吸管理に難渋した先天性気管狭窄を合併した 超低出生体重児の一例
中目 和彦,當瀬 ちひろ,桝屋 隆太,村岡 純輔,山田 直史, 青木良則,牧 洋平,牧 愛美 ,山内 綾 , 山下 理絵,金子政時 ,児玉 由紀,桂木 真司 ,七島 篤志森田 圭一,畠山 理
第58回日本周産期・新生児医学会学術集会 2022.7.12
Event date： 2022.7.10 - 2022.7.12
Language：Japanese Presentation type：Oral presentation (general)
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臍帯ヘルニアから見えた腹壁破裂の遷延性貧血 国内5施設の後方視的観察研究
杉田 光士郎, 武藤 充, 大城 清哲, 久田 正昭, 金城 僚, 桝屋 隆太, 町頭 成郎, 川野 孝文, 中目 和彦, 鳥飼 源史, 茨 聡, 加治 建, 家入 里志
第59回日本小児外科学会学術集会 2022.5.21
Event date： 2022.5.19 - 2022.5.21
Language：Japanese Presentation type：Oral presentation (general)
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地域医療を支える小児外科医の働き方改革はどうあるべきか? 宮崎県の場合
永田 公二, 林田 真, 三好 きな, 谷口 直之, 桝屋 隆太, 中目 和彦, 七島 篤志, 家入 里志, 田尻 達郎
第59回日本小児外科学会学術集会 2022.5.20
Event date： 2022.5.19 - 2022.5.21
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
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新生児消化管穿孔と動脈管開存の関連性に関する検討 過去10年間の経験症例をもとに
武藤 充, 生駒 真一郎, 村上 雅一, 川野 正人, 杉田 光士郎, 山田 和歌, 桝屋 隆太, 松久保 眞, 川野 孝文, 町頭 成郎, 坂本 浩一, 中目 和彦, 新山 新, 鳥飼 源史, 池江 隆正, 野口 啓幸, 茨 聡, 家入 里志
第59回日本小児外科学会学術集会 2022.5.20
Event date： 2022.5.19 - 2022.5.21
Language：Japanese Presentation type：Oral presentation (general)
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術前に判明した右肝動脈の破格を伴う先天性胆道拡張症に対する腹腔鏡手術の工夫
桝屋 隆太, 中目 和彦, 三好 きな, 松久保 眞, 七島 篤志, 家入 里志
第59回日本小児外科学会学術集会 2022.5.21
Event date： 2022.5.19 - 2022.5.21
Language：Japanese Presentation type：Oral presentation (general)
Grant-in-Aid for Scientific Research 【 display / non-display 】
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GVHD誘導マウスでのサイトカイン阻害による胆道閉鎖症の炎症標的型治療法の開発
Grant number：23K08052 2023.04 - 2026.03
独立行政法人日本学術振興会 科学研究費基金 基盤研究(C)
桝屋 隆太
Authorship：Coinvestigator(s)
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新生児壊死性腸炎の死亡0を目指した核酸医薬RAGEアプタマーによる革新的治療法の開発
Grant number：23K07281 2023.04 - 2026.03
独立行政法人日本学術振興会 科学研究費補助金 基盤研究(C)
Authorship：Coinvestigator(s)