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Affiliation |
Faculty of Medicine College Hospital Pediatrics department |
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Title |
Assistant Professor |
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External Link |
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KAMIMURA Sachiyo
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Papers 【 display / non-display 】
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Severe Traumatic Brain Injury in a Patient with von Willebrand Disease Type 2A Successfully Treated with Factor VIII/von Willebrand Factor Concentrates: A Case Report.
Koroki T, Abe T, Kamimura S, Ochiai H
The American journal of case reports 23 e936690 2022.8
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.12659/AJCR.936690
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Kinoshita M., Yamada A., Saito Y., Kamimura S., Moritake H.
Pediatrics international : official journal of the Japan Pediatric Society 64 ( 1 ) e14975 2022.1
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Pediatrics international : official journal of the Japan Pediatric Society
DOI： 10.1111/ped.14975
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Nagasawa S., Yamada A., Kinoshita M., Kamimura S., Moritake H.
Pediatrics international : official journal of the Japan Pediatric Society 64 ( 1 ) e14970 2022.1
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Pediatrics international : official journal of the Japan Pediatric Society
DOI： 10.1111/ped.14970
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Yamada A., Kinoshita M., Kamimura S., Nakame K., Moritake H.
Journal of Pediatric Hematology/Oncology 44 ( 2 ) E589 - E592 2021
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Journal of Pediatric Hematology/Oncology
Neuroblastoma with bone metastasis is well known to have an extremely poor prognosis. We experienced the case of a patient with adrenal ganglioneuroblastoma (GNB) with metastases of subcutaneous nodules, a lymph node, and multiple bones. A pathologic examination of tumors from different sites revealed both GNB and ganglioneuroma. A genetic comparison between these tumors identified the same molecular signatures, suggesting the possibility of spontaneous differentiation in the remaining GNB. The patient has been healthy without aggressive chemotherapy, and the patient's pathologic urinary catecholamines normalized. Even if unusual, we have to recognize probable spontaneous differentiation from neuroblastoma to GNB and then to ganglioneuroma, even in sites of bone metastasis.
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Yokoyama Ryohei, Yamada Ai, Kinoshita Mariko, Sawa Daisuke, Saito Yusuke, Kamimura Sachiyo, Moritake Hiroshi
The Japanese Journal of Pediatric Hematology / Oncology 58 ( 1 ) 40 - 44 2021
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japanese Society of Pediatric Hematology / Oncology
Ewing sarcoma (ES) is a malignant tumor originating from bone and soft tissue, and it frequently occurs in children and young adults. Although patients with localized ES normally have a disease-free survival rate of 70%, those with metastatic ES and who are refractory to primary chemotherapy have an extremely poor prognosis. We report on the case of a 19-year-old male diagnosed as having ES, who had an <i>EWSR1-FLI1</i> chimeric transcript originating from the right iliac bone. Chest computed tomography revealed multiple pulmonary metastases. He received VDC-IE consisting of vincristine, doxorubicin, cyclophosphamide, ifosfamide, and etoposide, followed by high-dose chemotherapy including busulfan and melphalan with autologous peripheral blood stem cell rescue and local radiotherapy. Afterwards, several lines of additional chemotherapy were performed; however, they failed to achieve a complete response. The administration of pazopanib induced a transient response, which allowed him to survive for an additional 7 months. Pazopanib is thus an available treatment option for refractory ES.
DOI： 10.11412/jspho.58.40
MISC 【 display / non-display 】
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Prevention of cisplatin-induced hearing-loss by sodium thiosulfate in medulloblastoma
Harao T., Yamada A., Kinoshita M., Kamimura S., Moritake H.
Pediatrics International 62 ( 10 ) 1204 - 1206 2020.10
Language：Japanese Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：Pediatrics International
DOI： 10.1111/ped.14271
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Noguchi M., Moritake H., Kamimura S., Sonoda M., Ishimura M., Inagaki J.
Bone Marrow Transplantation 53 ( 9 ) 1214 - 1217 2018.9
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution) Publisher：Bone Marrow Transplantation
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Yamada A., Moritake H., Kinoshita M., Sawa D., Kamimura S., Iwamoto S., Yamashita Y., Inagaki J., Takahashi T., Shimada A., Obara M., Nunoi H.
Pediatrics International 58 ( 9 ) 905 - 908 2016.9
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution) Publisher：Pediatrics International
© 2016 Japan Pediatric Society Inversion of chromosome 16 [inv(16)] has a good prognosis in acute myeloid leukemia (AML), but additional genetic aberrations influence the outcome. We herein describe the case of a 15-year-old Japanese boy with inv(16) harboring a low-allelic burden internal tandem duplication of FLT3 (FLT3-ITD) and KIT mutations. Conventional chemotherapy eradicated a clone with a low-al lelic burden FLT3-ITD mutation, although another clone with a KIT mutation occurred 17 months later. Further investigation is necessary to identify AML with inv(16) conferring poor prognosis, to facilitate appropriate treatment with additional drugs, such as dasatinib or gemtuzumab ozogamicin.
DOI： 10.1111/ped.13010
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Moritake H., Shimonodan H., Marutsuka K., Kamimura S., Kojima H., Nunoi H.
American Journal of Hematology 86 ( 1 ) 75 - 78 2011.1
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution) Publisher：American Journal of Hematology
DOI： 10.1002/ajh.21887