金子 泰之 (カネコ ヤスユキ)

KANEKO Yasuyuki

写真a

職名

助教

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  • 宮崎大学 -  獣医学

 

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  • Disseminated Pneumocystosis in a Toy Poodle

    Sakashita T., Kaneko Y., Izzati U.Z., Hirai T., Fuke N., Torisu S., Yamaguchi R.

    Journal of Comparative Pathology   175   85 - 89   2020年02月  [査読有り]

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    © 2020 Elsevier Ltd A 1-year and 7-months-old neutered male toy poodle was presented with persistent respiratory distress, gradual weight loss and melaena. Thoracic radiography showed an unstructured interstitial lung pattern. Histopathological examination of tissues collected at necropsy examination revealed disseminated infection by Pneumocystis carinii. The organisms were detected in the lungs, lymph nodes, liver, heart, kidneys, spleen, gastrointestinal tract and pancreas. In the lungs, the organisms were present in the alveolar space and interstitial tissue, and calcified foci containing P. carinii were observed. The presence of the organism in non-thoracic lymph nodes provided evidence of lymphogenous spread. A definitive diagnosis of disseminated pneumocystosis was achieved through the use of Grocott methenamine silver staining, immunohistochemistry (IHC) and polymerase chain reaction for P. carinii. Depletion of cells expressing immunoglobulin (Ig)A and IgG was confirmed by IHC of lymphoid tissue, suggesting possible underlying immunodeficiency.

    DOI

  • Effects of a single-bolus bupivacaine injection into the coccygeal spinal canal of rabbits.

    Ong BHE, Hidaka Y, Kaneko Y, Yamamoto S, Mizutani S, Sekiguchi S, Torisu S, Naganobu K

    The Journal of veterinary medical science     2020年01月  [査読有り]

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    <p>It has been reported that drugs intended for epidural administration through the lumbosacral junction are accidentally administered into the subarachnoid space frequently in rabbits. Therefore, we evaluated the epidural single-bolus injection technique for the administration of bupivacaine into the coccygeal spinal canal of rabbits. After epidural distribution was confirmed by the injection of iohexol into the coccygeal spinal canal, 0.3 m<i>l</i>/kg 0.5% bupivacaine or 0.3 m<i>l</i>/kg normal saline was injected via the same needle. After the first attempt of iohexol injection, although the contrast was found in the epidural space in all rabbits, the additional contrast was also found in blood vessel in 3 rabbits and in muscular layer in 1 rabbit. Subarachnoid distribution was not observed in any of the rabbits. The time taken to regain normal anal reflex, movement of the hind limbs during walking, conscious proprioception of the hind limbs, and pain sensation of the tail and left hind limb, following coccygeal spinal canal injection, were significantly longer in the bupivacaine group than in the normal saline group. These findings indicated that coccygeal epidural injection of bupivacaine in rabbits may provide anesthesia for the hind limbs, perineum, and tail, but inadvertent vascular entry of the epidural drug may occur.</p>

    DOI PubMed CiNii

  • Severe Degenerative Changes in Cryptorchid Testes in Japanese Black Cattle

    Fuke N., Kitahara G., Ito S., Van Diep N., Ping Teh A.P., Izzati U.Z., Myint O., Hirai T., Torisu S., Kaneko Y., Sato H., Hidaka Y., Osawa T., Yamaguchi R.

    Veterinary Pathology   57 ( 3 ) 418 - 426   2020年  [査読有り]

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    © The Author(s) 2020. This is a histopathologic and endocrinologic study of 6 calves diagnosed with cryptorchidism. Cases 1–3 were diagnosed as resembling testicular regression syndrome. In cases 1 and 2, the extracted tissue was a small, firm, gray-white mass, and there was lack of obvious testicular tissue in case 3. Histopathologically, the excised tissue in cases 1–3 was a fibrotic testicular remnant with inflammation, mineralization, hemosiderin-laden macrophages or lipofuscin-laden macrophages, and lack of germ cells and interstitial endocrine cells. These findings were compared with cases 4–6, which were diagnosed as testicular hypoplasia due to cryptorchidism. These cases had small but otherwise grossly unremarkable intra-abdominal testicular tissue and histologically had a few germ cells and sustentacular cells with arrested spermatogenesis and an increase in interstitial endocrine cells. Cases 1–3 had more severe degenerative changes compared with cases 4–6. In case 2, the average diameter of the seminiferous tubules was much smaller than in cases 4–6, and there were few tubule cross sections. Anti-Müllerian hormone (214 pg/ml) was detected in the plasma of case 2. Based on the macroscopic and histopathologic findings as well as endocrinologic profiles, the testicular degeneration in cases 1–3 was considered similar to that of testicular regression syndrome. In this condition, it is thought that a normally developing intra-abdominal testis undergoes degeneration due to heat or a vascular disorder such as torsion.

    DOI PubMed

  • Usefulness of Urinary Creatinine/Urea Nitrogen Ratio as Indicator of Body Protein Catabolism in Dogs Fed Low Protein Diets

    Yamamoto S., Ohta Y., Hasegawa E., Hashida S., Kaneko Y., Mizutani S., Ong B., Naganobu K., Torisu S.

    Frontiers in Veterinary Science   6   449   2019年12月  [査読有り]

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    © Copyright © 2019 Yamamoto, Ohta, Hasegawa, Hashida, Kaneko, Mizutani, Ong, Naganobu and Torisu. Low protein diets (LPs) constitute a reportedly effective form of nutritional therapy for canine chronic kidney disease and cirrhosis. These diets have long been feared to result in reduced muscle mass due to protein catabolism. This adverse effect, however, remains largely unrecognized in veterinary medicine as there are no easily applicable catabolism indicators. Therefore, we focused on urinary creatinine, a metabolite of protein in the urine, and examined whether its ratio to urinary urea nitrogen (UCrn/UN) can be used to assess protein catabolism. In Experiment 1, we first consecutively fed seven healthy beagles an LP, standard protein (SP), and high protein (HP) diet for 1 week each and then measured the UCrn/UN ratio at 2-h intervals from fasting to 16 h post-prandially. We consequently found that the UCrn/UN ratio was significantly elevated in the LP pre-prandially and at all post-prandial measurement points (P < 0.01). No significant differences were observed between the SP and HP. Analysis of fasting plasma amino-acid concentrations revealed that the concentration of methionine was significantly lower in the LP than in the other diets (P < 0.05). Although the effects of this change in amino-acid concentration were unclear, the UCrn/UN ratio was considered having increased due to a deficiency in protein and/or amino acids during LP feeding. In Experiment 2, we continuously fed five healthy beagles an LP for 18 weeks and then measured the UCrn/UN ratio as described above. We also measured changes in body composition with computed tomography. At weeks 10 and 18, the fasting UCrn/UN ratio was significantly higher than it was prior to the start of the LP; however, post-prandially, the UCrn/UN ratio decreased to the point that the significant difference disappeared. Muscle mass decreased at weeks 10 and 18. These results suggest that the fasting UCrn/UN ratio could be used as an indicator of protein catabolism in LP feeding. Our experiments thus indicate that examination of potential increases in the UCrn/UN ratio 1 week after introduction of LP feeding to healthy dogs could enable detection of body protein catabolism in long-term feeding of LP before muscle breakdown occurs.

    DOI PubMed

  • Hydroxyl radical formation in lactated ringer’s solution and BSS plus® intraocular irrigating solution

    Naganobu K., Nakajima A., Kaneko Y., Torisu S., Sekiguchi S., Chuman H.

    Japanese Journal of Veterinary Research   67 ( 3 ) 209 - 214   2019年  [査読有り]

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    © Hokkaido University, All rights reserved. Free radicals generated during phacoemulsification, a method of cataract surgery, have been shown to damage corneal endothelial cells. We compared hydroxyl radical formation (HRF) in lactated Ringer’s solution (LRS) and BSS Plus® intraocular irrigating solution, as well as physiological saline solution (PSS) and Ringer’s solution (RS). Hydroxyl radicals were generated by a phacoemulsification machine or UV irradiation in the presence of hydrogen peroxide. We measured DMPO-hydroxyl radical adducts using ESR. HRF did not significantly differ between LRS and BSS Plus®, and tended to be smaller in LRS and BSS Plus® than in PSS or RS. Even if corneal damage after phacoemulsification in LRS is different from that in BSS Plus®, the influence of HRF on this difference may be small.

    DOI

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総説・解説記事 【 表示 / 非表示

  • 臨床獣医師のための内科文献情報

    金子 泰之

    SA Medicine   26 ( 152 ) 71 - 71   2020年04月  [依頼有り]

    総説・解説(商業誌)   単著

  • 胆道系手術の合併症

    金子 泰之

    SURGEON   24 ( 24 ) 38 - 57   2020年01月  [依頼有り]

    総説・解説(商業誌)   単著

  • 胆嚢粘液嚢腫(胆嚢穿孔、破裂を起こしていた症例)

    金子 泰之

    VETERINARY BOARD   1 ( 1 ) 38 - 46   2019年05月  [依頼有り]

    総説・解説(商業誌)   単著

  • Oncologic Emergency ~胆道閉塞~

    金子 泰之、鳥巣至道

    Vetrinary Oncology   6 ( 1 ) 58 - 63   2019年01月  [依頼有り]

    総説・解説(商業誌)   共著

  • ヘマブロック Case Report 7

    金子 泰之

    Small Animal Clinic   191   2018年07月  [依頼有り]

    総説・解説(商業誌)   単著

学術関係受賞 【 表示 / 非表示

  • 第98回獣医麻酔外科学会 軟部組織外科部門 優秀賞

    2019年06月   第98回獣医麻酔外科学会    人工腸弁形成により症状改善が認められた短結腸症の犬の1例  

    受賞者:  金子泰之,鳥巣至道,日高裕貴,水谷真也,山本集士,Benedict Huai Ern ONG,永延清和

  • 第90回獣医麻酔外科学会 軟部組織外科部門 研究発表 優秀賞

    2015年06月   獣医麻酔外科学会   犬における術中順行性胆道造影の有用性の検討  

    受賞者:  ○金子泰之、鳥巣至道、水谷真也、永延清和

  • 第55回日本伝統獣医学会大会 理事長賞

    2015年06月   日本伝統獣医学会   イヌの胆嚢疾患における酸化ストレスの検討  

    受賞者:  ○金子泰之、都築直、橋本千晶、水谷真也、鳥巣至道

  • 第65回九州地区獣医師大会 フレッシャーアワード

    2016年10月   第65回九州地区獣医師大会   犬と猫の周術期における血中アンモニア値と血中乳酸値に関する検討  

    受賞者:  ○高橋愛美、鳥巣至道、金子泰之、水谷真也、山本集士、永延清和

  • 第61回九州地区獣医師大会 九州地区学会長賞

    2012年10月   第61回九州地区獣医師大会(宮崎)   牛の立位による腹腔鏡下潜在精巣摘出術の検討  

    受賞者:  ○金子 泰之、鳥巣至道、北原豪、佐藤裕之、日高勇一、大澤健司 、永延清和

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  • 軟部外科 症例検討会

    金子 泰之  [招待有り]

    第98回日本獣医麻酔外科学会   (大阪国際交流センター)  2020年01月  -  2020年01月    一般社団法人日本獣医麻酔外科学会

  • 人工腸弁形成により症状改善が認められた短結腸症の犬の1例

    金子泰之, 鳥巣至道, 日高裕貴, 水谷真也, 山本集士, Benedict Huai Ern ONG, 永延清和  [招待有り]

    第99回日本獣医麻酔外科学会  (大阪国際交流センター)  2020年01月  -  2020年01月    一般社団法人日本獣医麻酔外科学会

  • A cat with congenital billiary dilation and suspected pancreatobiliary maljunction

    *Shinsuke Fujimoto1.2, Yasuyuki Kaneko1 , Shinya Mizutani1, Ong Benedict Huai Ern1, Shushi Yamamoto1 , Shidow Torisu1

    6th Asian Meeting of Animal Medicine Specialties  (Shanghai)  2019年10月  -  2019年10月    AMAMs2019

  • Examination of the usefulness of intraoperative antegrade cholangiography in dogs

    Kaneko Y, Torisu S, Mizutani S, Yamamoto S, Ong BH and Naganobu K

    6th Asian Meeting of Animal Medicine Specialties  (Shanghai )  2019年10月  -  2019年10月    AMAMS 2019

  • 免疫不全疑い犬における遺伝子診断:CD40Ligandの点変異の同定

    森正太郎, 新井良和, 金子泰之, 鳥巣至道, 西野光一郎

    第162回日本獣医学会学術集会  (つくば国際会議場)  2019年09月  -  2019年09月    公益社団法人日本獣医学会

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