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Affiliation |
Faculty of Medicine College Hospital Endoscopic Medicine/Center for Degestive Disease |
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Associate Professor |
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External Link |
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Related SDGs |
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TAKENO Shinsuke
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Research Areas 【 display / non-display 】
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Life Science / General surgery and pediatric surgery / Thoracic Surgery
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Life Science / Experimental pathology / Experimental Pathology
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Life Science / Digestive surgery / Digestive Organ Surgery
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Life Science / Human pathology / Human Pathology
Papers 【 display / non-display 】
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Salvage Esophagectomy after Photodynamic Therapy for Secondary Squamous Cell Carcinoma in a Patient with a History of Complete Response to Chemoradiotherapy for Unresectable Advanced Esophageal Neuroendocrine Carcinoma Reviewed
Araki Yusuke, Takeno Shinsuke, Ikenoue Makoto, Tashiro Kosei, Kawano Fumiaki, Ochiai Takahiro, Shimizu Ikko, Chiyotanda Teru, Tahira Kosei, Ota Yusuke, Nakashima Koji, Nanashima Atsushi
Nihon Kikan Shokudoka Gakkai Kaiho 76 ( 3 ) 167 - 173 2025.6
Language：English Publishing type：Case report Publisher：The Japan Broncho-esophagological Society
Esophageal neuroendocrine carcinoma (NEC) is a relatively rare esophageal malignancy with high histological grade and poor prognosis. Chemotherapy with or without radiation is recommended because NEC is often detected at an advanced stage and the recurrence rate is relatively high. For esophageal cancer, photodynamic therapy (PDT) is indicated after chemoradiotherapy (CRT), and salvage surgery is rarely performed afterwards. We report here a case in which PDT and salvage surgery were performed for secondary esophageal squamous cell carcinoma after esophageal NEC showed complete response to CRT. Eighteen months before this presentation, a 71-year-old woman underwent CRT for esophageal NEC (cT4b (trachea) N2M0 Stage IV) and no residual lesion was detected. Upper gastrointestinal endoscopy revealed multiple superficial-type squamous cell carcinomas in the esophagus at 25, 26, and 38 cm from the incisors. The lesion 38 cm from the incisors had invaded to the submucosal layer and the others represented in situ carcinomas. PDT was performed twice for all lesions, but residual tumor remained at 38 cm from the incisors. Ivor Lewis esophagectomy was performed because the earlier NEC had invaded to the trachea before CRT. Intraoperative findings included edema and scarring of the esophageal wall. The postoperative course was good and the patient was discharged on postoperative day 23.
DOI： 10.2468/jbes.76.167
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Delorme Procedure for Mucosal Prolapse after Laparoscopic Intersphincteric Resection: A Case Report Reviewed
Ichihara Akiko, Takeno Shinsuke
Nihon Daicho Komonbyo Gakkai Zasshi 78 ( 6 ) 257 - 261 2025.6
Authorship：Last author Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japan Society of Coloproctology
A 45-year-old man underwent laparoscopic-assisted partial ISR for additional resection of rectal neuroendocrine tumor after endoscopic submucosal dissection. The patient recognized mucosal prolapse following stoma closure at four months postoperatively and underwent DP for prolonged dyschezia with frequent bowel movements and incontinence. Mucosal detachment was performed transanally at the oral side of the anastomosis to form the 8-cm mucosal tube. The muscle layer was sutured circumferentially from the dentate line side, and the mucosal tube was resected and anastomosed. Surgery was completed after confirming the reduction of the intestinal tract and anal skin inversion. The patient experienced no perioperative complications, improved dyschezia, and had no recurrence of mucosal prolapse or neuroendocrine tumor at one year and four months after DP. DP can be performed safely in patients with mucosal prolapse after ISR and is an effective treatment option. We studied the mechanism of postoperative mucosal prolapse and its prevention, including innovative techniques for ISR.
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河野 文彰, 千代反田 顕, 中目 和彦, 明利 聡瑠, 福島 剛, 佐藤 勇一郎, 山口 秀樹, 池ノ上 実, 宗像 駿, 樋口 和宏, 武野 慎祐, 七島 篤志
Endocrinology Diabetes and Metabolism Case Reports 2025 ( 2 ) e250014 2025.5
Language：English Publishing type：Case report Publisher：Bioscientifica
Summary
Spindle epithelial tumor with thymic-like elements (SETTLE) is an extremely rare tumor that occurs primarily in the thyroid gland. Histologically, SETTLE is characterized by the presence of spindle-shaped epithelial cells and glandular structures. However, it is known that diagnosis via fine-needle aspiration cytology can be challenging. SETTLE predominantly occurs in younger individuals and has a less favorable prognosis compared to differentiated thyroid carcinoma. Therefore, ensuring accurate diagnosis and appropriate treatment is crucial. We encountered a case of spindle epithelial tumor with thymus-like differentiation in a 10-year-old patient for whom the preoperative diagnosis was successfully established through fine-needle aspiration cytology, which facilitated appropriate surgical resection. Comprehensive histopathological examination and immunohistochemical analysis are essential to ensure appropriate management and surveillance of SETTLE.
Learning points
A rare thyroid tumor, spindle epithelial tumor with thymic-like elements (SETTLE), was diagnosed preoperatively and treated surgically.
SETTLE presents with characteristic histological features that must be recognized for accurate diagnosis. In addition, diagnosis through cytology is often challenging.
The primary treatment for SETTLE is surgical intervention as radiotherapy and pharmacological treatments are generally not expected to be highly effective.
Radical resection is the only effective treatment, making the selection of the surgical procedure according to the stage of the disease essential.DOI： 10.1530/EDM-25-0014
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Strategies for NOMI : Toward standardization with ICG fluorography Reviewed
Ochiai Takahiro, Kawano Fumiaki, Ikenoue Makoto, Takeno Shinsuke, Nanashima Atsushi
Japanese Journal of Acute Care Surgery advpub ( 0 ) 2025.4
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japanese Society for the Acute Care Surgery
Non-occlusive mesenteric ischemia （NOMI） is a disease that results in impaired intestinal blood flow without organic obstruction of the main trunk of mesenteric vessels. Despite improvements in diagnosis and surgical treatment, it remains an emergency condition with a high mortality rate. At our hospital, before 2021, the physician in charge individually decided the treatment plan and surgical procedure for NOMI, but after 2022, indocyanine green （ICG） fluorescence angiography, open abdominal management （OAM）, and second-look operation were standardized in all cases. With this strategy, after naked eye confirmation of an abnormal color of the intestinal tract, blood flow is evaluated using ICG fluorescence angiography, and the extent of resection is determined. A second-look operation is performed within 48 hours after OAM without anastomosis, during which ICG fluorescence angiography is also performed. These procedures support the surgeon in determining the extent of the resection required, and reduce the surgeon's mental stress. We would like to continue further studies to improve surgical outcomes and the prognosis of NOMI by accumulating cases in which these strategies are used.
DOI： 10.50840/jjacs.15-3
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What should acute care surgery be like in regional facilities? Reviewed
Kawano Fumiaki, Tashiro Kousei, Ikenoue Makoto, Munakata Shun, Suzuki Yasuto, Takeno Shinsuke, Furukawa Kouji, Ochiai Hidenobu, Nanashima Atsushi
Japanese Journal of Acute Care Surgery 15 ( 1 ) 2025.4
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japanese Society for the Acute Care Surgery
We looked back on the 10 years of acute care surgery 〈ACS） at our department and discussed what type of ACS is required in facilities in regional cities. In our department, the emergency and critical care unit started in 2012, which required major changes in the surgical emergency treatment system. At the regional level, we focused on maintaining the existing emergency system, and we established a system in which severe injuries and trauma cases were concentrated in our department. At the facility level, ACS team was formed with existing surgeons to facilitate trauma care and actively intervene in trauma care. In addition, to maintain the team, we improved the on-call system and implemented complete division of labor in perioperative management. At the individual level, we performed daily surgical tasks with a specialty to maintain surgical skills and motivation. In addition, we made efforts to encourage young surgeons and residents to intervene in the practice in order to foster the Acute care surgeons. In this way, we believe that ACS in regional cities can be established by maintaining the existing emergency system and having existing surgeons create a system that is suited to the facilities.
DOI： 10.50840/jjacs.15-1
Books 【 display / non-display 】
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Kyoto Summer Institute, 武野 正三
Springer-Verlag 1985
Language：Japanese
MISC 【 display / non-display 】
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特集 必携 消化器・一般外科医のための外科解剖アトラス【I 食道・胃1】食道癌頸部リンパ節郭清に必要な局所解剖 Invited Reviewed
武野慎祐，河野文彰，田代耕盛，池ノ上実，七島篤志，井手慎介
手術 78 ( 4 ) 395 - 402 2024.3
Authorship：Lead author, Corresponding author Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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特集 臓器損傷治療の工夫 【手術手技】 腹部開放創陰圧治療法システムによるopen abdominal management Invited Reviewed
桝屋隆太, 中目和彦, 宗像 駿, 河野文彰, 武野慎祐, 七島篤志, 家入里志
小児外科 57 ( 2 ) 231 - 235 2025.2
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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特集【Acute Care Surgery入門-外傷対応の基礎知識】Open abdominal management-若手外科医が知っておくこと Invited Reviewed
河野文彰，池ノ上実，宗像 駿，武野慎祐，七島篤志
臨床外科 79 ( 12 ) 1233 - 1241 2024.11
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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【診療】当院におけるNOMIの治療戦略 Invited Reviewed
落合貴裕，河野文彰，田代耕盛，池ノ上実，古川貢之，落合秀信，武野慎祐，七島篤志
宮崎県医師会医学会誌 48 ( 1 ) 31 - 37 2024.3
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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【診療】鏡視下甲状腺手術の現状と課題 Invited Reviewed
河野文彰，田代耕盛，池ノ上実，落合貴裕，清水一晃，千代反田顕，古川貢之，武野慎祐，七島篤志
宮崎県医師会医学会誌 48 ( 1 ) 42 - 47 2024.3
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
Presentations 【 display / non-display 】
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内視鏡切除後に外科的追加切除が必要となった食道悪性腫瘍症例の検討
田代耕盛，武野慎祐，河野文彰，千代反田顕，宗像 駿，宮﨑康幸，濵田朗子，中島孝治，三池 忠，河上 洋，七島篤志，中村都英
第2回宮崎食道癌研究会 (宮崎) 宮崎食道癌研究会
Event date： 2018.3.16
Language：Japanese Presentation type：Oral presentation (general)
Venue：宮崎
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当院における外傷性腹壁破裂の経験例．
田代耕盛，河野文彰，守永圭吾，池田拓人，武野慎祐，落合秀信，七島篤志，中村都英
第54回日本腹部救急医学会総会 (東京) 日本腹部救急医学会
Event date： 2018.3.8 - 2018.3.9
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京
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手術適応に苦慮した腸管気腫性嚢胞症の1例．
千代反田顕，河野文彰，田代耕盛，西田卓弘，宮崎康幸，宗像 駿，落合貴祐，清水一晃，長友謙三，濱田朗子，鈴東昌也,市原明子，池田拓人，武野慎祐，七島篤志
第54回日本腹部救急医学会総会 (東京) 日本腹部救急医学会
Event date： 2018.3.8 - 2018.3.9
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京
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当院での外傷性副腎損傷の経験．
宗像 駿，河野文彰，田代耕盛，池ノ上実，池田拓人，武野慎祐，榮 建文，中村都英，落合秀信，七島篤志
第54回日本腹部救急医学会総会 (東京) 日本腹部救急医学会
Event date： 2018.3.8 - 2018.3.9
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京
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精巣癌の空腸転移による腸重積の1例．
清水一晃，武野慎祐，河野文彰，田代耕盛，西田卓弘，濵田朗子，田上幸憲，七島篤志
第54回日本腹部救急医学会総会 (東京) 日本腹部救急医学会
Event date： 2018.3.8 - 2018.3.9
Language：Japanese Presentation type：Oral presentation (general)
Venue：東京