INOUE Yoshiyuki

写真a

Affiliation

Faculty of Agriculture Department of Veterinary Science

Title

Assistant Professor

External Link

Degree 【 display / non-display

  • 獣医学博士 ( 2013.3   山口大学 )

Research Areas 【 display / non-display

  • Life Science / Veterinary medical science

 

Papers 【 display / non-display

  • Surgical Treatment of a Retropharyngeal Abscess in a Japanese Black Cow

    Okada S., Sueun K., Ichikado R., Kuroda K., Inoue Y., Nakama Y., Satoh H., Sato R.

    Veterinary Sciences   9 ( 8 )   2022.8

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Veterinary Sciences  

    A 17-month-old Japanese Black cow presented with inappetence, wheezing, dysphagia, and drooling. Radiography and ultrasonography revealed an oval, dorsal, pharyngeal mass, with an internal horizontal line demarcating the radiolucent area from the radio-opaque area. Upper airway endoscopy revealed pus-like deposits in the dorsal nasal passage, hyperemia, and edema in the dorsal pharynx, leading to swelling and airway obstruction. Manual palpation, after sedation, revealed a thickened mass surface, which was difficult to rupture with manual pressure. After inserting a linear sonographic probe through the mouth to establish the vascularity surrounding the mass and to identify a relatively thin-walled area, a trocar was pierced into the mass under endoscopic guidance, and the opening was enlarged manually. The mass was filled with stale pus-like material, which was removed manually. The abscess cavity was washed using saline and povidone–iodine. Day 1 post-surgery, dysphagia and wheezing disappeared. Day 16 post-surgery, endoscopy showed significant improvement in the airway patency. One year postoperatively, the owner reported that the cow had an uneventful recovery. For deep abscesses, such as bovine pharyngeal abscesses, it is important to perform a preoperative transoral Doppler ultrasonography to assess the vascularity and thickness of the abscess wall for safe trocar insertion and abscess drainage.

    DOI: 10.3390/vetsci9080446

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  • Identification of domestic cat hepadnavirus from a cat blood sample in Japan. Reviewed

    Takahashi K, Kaneko Y, Shibanai A, Yamamoto S, Katagiri A, Osuga T, Inoue Y, Kuroda K, Tanabe M, Okabayashi T, Naganobu K, Minobe I, Saito A

    The Journal of veterinary medical science   2022.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.22-0010

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  • Radiographic diagnosis and surgical management for successful outcomes for osteochondrosis in Japanese Black calves. Reviewed

    Mrunmayi Vishwanath Naik, Yumi Kirino, Ryoko Uemura, Sueun Kim, Yoshiyuki Inoue, Yuichi Hidaka

    The Journal of veterinary medical science   83 ( 1 )   151 - 157   2021.1

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:JAPANESE SOCIETY OF VETERINARY SCIENCE  

    DOI: 10.1292/jvms.20-0310

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  • Bilateral rostral mandibulectomy for treatment of necrotic mandibular open fractures in two Japanese Black cattle. Reviewed

    Naik MV, Nishikawa G, Kirino Y, Inoue Y, Iwamoto K, Yamabe R, Nakayama T, Tsuzuki N, Hidaka Y

    The Journal of veterinary medical science   82 ( 2 )   204 - 208   2020.2

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:公益社団法人 日本獣医学会  

    <p>Two-month-old (Case 1) and one-year-old (Case 2) Japanese Black cattle presented with bilateral rostral mandibular open fractures. At presentation, the proximal edges of each fracture were discolored and had a severe stench, indicating necrosis caused by infection. In both cases, a bilateral rostral mandibulectomy over the symphysis was performed. Although the tongues of both animals prolapsed post-surgery, they had no significant problems with eating or drinking. Case 1 showed excellent growth during fattening, and Case 2 successfully became pregnant and gave birth. Rostral mandibulectomy can be an effective surgical option for the treatment of cattle with difficulty in internal or external fixation due to unfavorable necrotic cranial mandibular open fractures.</p>

    DOI: 10.1292/jvms.19-0160

    PubMed

  • Des-acyl ghrelin prevents heatstroke-like symptoms in rats exposed to high temperature and high humidity

    Inoue Y., Hayashi Y., Kangawa K., Suzuki Y., Murakami N., Nakahara K.

    Neuroscience Letters   615   28 - 32   2016.2

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Neuroscience Letters  

    © 2016 Elsevier Ireland Ltd. We have shown previously that des-acyl ghrelin decreases body temperature in rats through activation of the parasympathetic nervous system. Here we investigated whether des-acyl ghrelin ameliorates heatstroke in rats exposed to high temperature. Peripheral administration of des-acyl ghrelin significantly attenuated hyperthermia induced by exposure to high-temperature (35°C) together with high humidity (70-80%). Although biochemical analysis revealed that exposure to high temperature significantly increased hematocrit and the serum levels of aspartate amino transferase (AST), alanine transaminase (ALT), blood urea nitrogen (BUN), creatinine and electrolytes (Na+, K+, Cl-), most of these heatstroke-associated reactions were significantly reduced by treatment with des-acyl ghrelin. The level of des-acyl ghrelin in plasma was also found to be significantly increased under high-temperature conditions. These results suggest that des-acyl ghrelin could be useful for preventing heatstroke under high temperature condition.

    DOI: 10.1016/j.neulet.2016.01.003

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  • Intra-abdominal mass containing controlled internal drug release (CIDR) devices detected by CT in a Japanese Black cow

    SATO Reiichiro, SATOH Hiroyuki, OKADA Shoichi, GODA Yoshimichi, SUEUN Kim, KURODA Kohei, INOUE Yoshiyuki, KITAHARA Go, OSAWA Takeshi

    Journal of Veterinary Medical Science   84 ( 8 )   1088 - 1092   2022

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    Language:Japanese   Publishing type:Rapid communication, short report, research note, etc. (scientific journal)   Publisher:JAPANESE SOCIETY OF VETERINARY SCIENCE  

    <p>This report describes an intra-abdominal mass caused by progesterone-containing controlled internal drug release (CIDR) devices in the abdominal cavity of a 28-month-old Japanese Black heifer presenting with infertility. Rectal examination revealed a mass containing a cartilage-like object in the pelvic cavity. Computed tomography revealed a mass containing two T-shaped foreign bodies. Laparotomy was performed to remove the mass containing the foreign bodies. The heifer was healthy at discharge seven days post-surgery. This case adds CIDR device as a new etiology for intra-abdominal masses. Furthermore, it highlights the usefulness of CT in diagnosing deep abdominal lesions.</p>

    DOI: 10.1292/jvms.22-0180

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Presentations 【 display / non-display

  • 『 犬の頸部椎間板ヘルニアに対する外科治療 』 腹側減圧術 Invited

    井上賀之

    年度第103回日本獣医麻酔外科学会学術集会パネルディスカッション 

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    Event date: 2022.3.18 - 2022.3.20

    Presentation type:Symposium, workshop panel (nominated)  

  • 小脳に発生したラブドイド髄膜腫の犬の1例

    井上賀之、黒田晃平、水谷真也、水谷祐子、佐藤裕之、 添田久仁子、二瓶和美、日高勇一

    令和3年度獣医学術九州地区学会 

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    Event date: 2021.10.22 - 2021.10.31

    Presentation type:Oral presentation (general)  

  • 頚長筋における化膿性肉芽腫性筋炎と診断された犬の1例

    井上賀之,中村健介,水谷祐子,高木千尋,Naik Mrunmayi Vishwanath,Kim Su Eun,土本彩花,城戸 洋,二瓶和美,日高勇一

    第16 回日本獣医内科学アカデミー学術大会 

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    Event date: 2020.2

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 先天性リンパ水腫と診断した黒毛和種牛の1例

    土本彩花,桐野有美,山内詩乃,柳 祐介,Naik Mrunmayi Vishwanath,Kim Su Eun,佐藤裕之,山口良二,保田昌宏,井上賀之,日高勇一

    日本産業動物獣医学会九州地区 

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    Event date: 2019.11.8

    Language:Japanese   Presentation type:Oral presentation (general)  

  • 椎孔内浸潤を示した犬のダンベル型悪性末梢神経鞘腫瘍の1例

    今富美波,平井卓哉,井上賀之,山口良二

    日本小動物獣医学会九州地区 

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    Event date: 2019.11.8

    Language:Japanese   Presentation type:Oral presentation (general)  

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Awards 【 display / non-display

  • 小動物獣医学会フレッシャーアワード

    2019.11   日本小動物獣医学会  

    井上賀之,土本彩花,水谷真也,水谷祐子,Naik Mrunmayi Vishwanath,坂井秀二,桐野有美,日高勇一

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 産業動物獣医学会九州獣医師連合会会長賞

    2019.11   日本産業動物獣医学会   内固定および外固定を併用して治療した踵骨骨折の黒毛和種子牛の1例

    井上賀之,加藤梨帆,茂木渉,Naik Mrunmayi Vishwanath,Kim Su Eun,桐野有美,日高 勇一

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 日本産業動物獣医学会九州地区連合会長賞

    2017.10   日本獣医産業動物獣医学会   両側下顎骨開放骨折に対し吻側下顎骨切除術を行った黒毛和種子牛の1例

    西川豪亜, 日高勇一, 岩本希生, Naik Mrunmayi Vishwanath, 山部竜正, 都築 直, 桐野有美, 井上賀之

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

Grant-in-Aid for Scientific Research 【 display / non-display

  • 新規ペプチド“NURP”と“NSRP”のトランスレーショナルリサーチ

    Grant number:20H03153  2020.04 - 2024.03

    日本学術振興会  科学研究費助成事業 基盤研究(B)  基盤研究(B)

    中原 桂子, 丸山 圭介, 永延 清和, 井上 賀之

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    Authorship:Principal investigator 

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  • Neuromedin U/Sとそれらの新規関連ペプチドの機能探索および橋渡し研究

    Grant number:18H02354  2018.04 - 2021.03

    日本学術振興会  科学研究費助成事業 基盤研究(B)  基盤研究(B)

    村上 昇, 井上 賀之, 中原 桂子

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    Authorship:Principal investigator 

    昨年に掲げた研究実施計画は、NMU,NMS, NURPおよびNSRPの4つのペプチドの作用部位の違いを明確にすることであった。その方法としては、それら4つのペプチドをラットの脳室内に投与し、投与後のcFos発現を蛍光免疫染色によって比較することを掲げた。その結果、NMU及びNMS投与群では、室傍核、視索上核、扁桃体中心核で顕著に多いcFos発現が認められたのに対し、NURP及びNSRP投与群では、視交叉上核、視索上核、扁桃体中心核でのcFos発現は認められなかった。弓状核ではどのペプチド投与群においてもcFos発現がみられたが、その領域は異なっており、NMU、NMS投与では弓状核内側領域で、NURP、NSRP投与では弓状核外側領域で発現が認められた。また、NURP投与群でのみ腹側海馬台においてcFos発現が認められた。さらに、視床下部前領域ではNSRP投与群で発現量が多く、動眼神経副核ではNMS投与群で発現量が多い傾向がみられた。NMU、NMSが同様の部位にcFos発現を示したのは、両者が同じ受容体のNMU-R1、R2に結合している結果であると思われる。一方で、NMUとNMSの前駆体中の新規ペプチドのNURPとNSRPはそれらと異なる作用部位に作用していることが推測された。さらにNURPとNSRPが同じような作用部位を示したことは、それらの分子のアミノ酸配列に一部ホモロジーの高い部位が存在するためと考えられる。しかし、腹側海馬台において両者が異なっていたことから、それぞれが別の受容体を有している可能性も否定できないとも考えられる。

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  • デスアシルグレリンの新規生理作用の探索ならびに受容体の同定

    2011.04 - 2013.03

    科学研究費補助金  特別研究員奨励費