Details of a Researcher

Optimization of zwitterionic polymers for cell cryopreservation Reviewed International journal

Yui Kato, Takuya Uto, Takeru Ishizaki, Daisuke Tanaka, Kojiro Ishibashi, Yuya Matsuda, Issei Onoda, Akiko Kobayashi, Masaharu Hazawa, Richard W. Wong, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda

Macromolecular Bioscience 24 ( 7 ) Article number: e2300499 2024.7

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1002/mabi.202300499

Extended ensemble simulation study of structural polysaccharide crystal structures Invited

Toshifumi Yui, Takuya Uto

Cellulose Communications 31 18 - 21 2024.3

Authorship：Last author Language：Japanese Publishing type：Research paper (scientific journal)

Physicochemical properties of pyrrolidinium-based room temperature ionic liquids with propoxyethyl, ethoxypropyl, or (methoxymethoxy)ethyl group Reviewed International journal

Kazuki Yoshii, Takuya Uto

Electrochemistry 92 ( 4 ) Article number: 043007 2024.2

Authorship：Last author,　Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：The Electrochemical Society of Japan

Room temperature ionic liquids (RTILs) with ether oxygen atoms in the side chain have been investigated for electrochemical applications because they show favorable transport properties compared with alkyl analogs. However, the influence of the position and number of ether oxygen atoms on physical properties has not yet been fully clarified. In the present study, the physicochemical properties of RTILs consisting of bis(trifluoromethanesulfonyl)amide (TFSA−) with 1-methy-1-propoxyethylpyrrolidinium (Pyr1,2O3+), 1-methyl-1-ethoxypropylpyrrolidinium (Pyr1,3O2+), and 1-methyl-1-(methoxymethoxy)ethylpyrrolidinium (Pyr1,2O1O1+) was investigated using experimental and computational approach. Pyr1,2O3TFSA exhibited the lowest viscosity and highest ionic conductivity. Pyr1,2O1O1TFSA with two oxygen atoms in the side chain showed relatively high viscosity, indicating the physicochemical properties were affected sensitively by the position and number of ether oxygen atoms. Furthermore, by comparing with the structural isomers reported so far, we were able to systematically discuss the introduction effect of ether oxygen on the physicochemical properties of RTILs.

DOI： 10.5796/electrochemistry.23-69154

Protein cryoprotectant ability of the aqueous zwitterionic solution Reviewed International journal

Takahiro Takekiyo, Shuto Yamada, Takuya Uto, Masaharu Nakayama, Tetsuya Hirata, Takeru Ishizaki, Kosuke Kuroda, Yukihiro Yoshimura

Journal of Physical Chemistry B 128 ( 2 ) 526 - 535 2024.1

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1021/acs.jpcb.3c05614

Cell-compatible isotonic freezing media enabled by thermo-responsive osmolyte-adsorption/exclusion polymer matrices Reviewed International journal

Yui Kato, Yuya Matsuda, Takuya Uto, Daisuke Tanaka, Kojiro Ishibashi, Takeru Ishizaki, Akio Ohta, Akiko Kobayashi, Masaharu Hazawa, Richard W. Wong, Kazuaki Ninomiya, Kenji Takahashi, Eishu Hirata, Kosuke Kuroda

Communications Chemistry 6 ( 1 ) Article number: 260 2023.12

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1038/s42004-023-01061-7

Control of thermal diffusivity of nanocellulose papers by introduction of metal ions Invited

Kojiro Uetani, Takuya Uto

Journal of the Japan Society of Colour Material 96 ( 7 ) 228 - 232 2023.7

Authorship：Last author Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Japan Society of Colour Material

Crystalline cellulose nanofibers (nanocelluloses) are produced through chemical purification and nanofibrillation of biomass such as ascidian mantles and wood flour. Nanocellulose with carboxy groups introduced on the surface is dried to make a freestanding paper, and when immersed in an aqueous solution of metal chloride, metal ions can be introduced into the nanocellulose paper. The thermal diffusivity of these metal ion-introduced papers was measured in a low-humidity environment and found to vary depending on the ionic radius and electronegativity. This review outlines the recently revealed thermal conductive properties of nanocellulose papers and the control of thermal diffusivity by ion introduction.

DOI： 10.4011/shikizai.96.228

Extended ensemble molecular dynamics study of ammonia-cellulose I complex crystal models: Free-energy landscape and atomistic pictures of ammonia diffusion in the crystalline phase Reviewed International journal

Toshifumi Yui, Takuya Uto, Kotaro Noda

Journal of Chemical Information and Modeling 63 ( 13 ) 4088 - 4099 2023.7

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1021/acs.jcim.3c00106

Strong attractive interaction between finite element models of twisted cellulose nanofibers by intermeshing of twists Reviewed International journal

Kojiro Uetani, Takuya Uto

RSC Advances 13 ( 24 ) 16387 - 16395 2023.5

Authorship：Last author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1039/d3ra01784b

Molecular dynamics simulation study of chitosan−zinc chloride complex model Reviewed

Kotaro Noda, Takuya Uto, Toshifumi Yui

Journal of Fiber Science and Technology 79 ( 2 ) 24 - 31 2023.3

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Society of Fiber Science and Technology, Japan

We report molecular dynamics simulation study of chitosan－zinc chloride complex crystal model to predict a hydrated structure and to evaluate the potential of mean force (PMF), namely, the free energy difference, in migration of a guest zinc chloride molecule in the crystal model. The accelerated molecular dynamics method was adopted to predict the hydrate structure of the crystal model, which proposed the crystal model interior involving four to five water molecules per a unit cell. The water molecules were mostly located in the crystal void surrounded by the functional groups of D-glucosamine and zinc chloride molecules, where the water molecules were mostly coordinated to zinc atoms. The PMF profile, obtained by using adaptive steered molecular dynamics method, exhibited continuously increase in the base line accompanied with appreciable minima, each of which corresponded to formations of interactions between the zinc chloride molecule and the polar functional groups, suggesting that the zinc chloride molecule on migration was handed over the C6 hydroxyl and C2 amino groups, while C3 hydroxyl groups were irrelevant to such an interaction. It was suggested that a zinc chloride molecule was more readily accommodated in the void through coordination with a C6 hydroxyl group which was more spatially mobile through C5-C6 bond rotation.

DOI： 10.2115/fiberst.2023-0004

Tunability of the thermal diffusivity of cellulose nanofibril films by addition of multivalent metal ions Reviewed International journal

Kojiro Uetani, Keitaro Kasuya, Soh Yoshikawa, Takuya Uto

Carbohydrate Polymers 297 Article number: 120010 2022.12

Authorship：Last author,　Corresponding author Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1016/j.carbpol.2022.120010

Theoretical study on dissolution mechanism of chitin crystal in ionic liquids Reviewed

Takuya Uto

Chitin and Chitosan Research 28 16 - 21 2022.4

Authorship：Lead author,　Last author,　Corresponding author Language：Japanese Publishing type：Research paper (scientific journal)