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Affiliation |
Faculty of Agriculture Department of Biochemistry and Applied Biosciences |
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Title |
Associate Professor |
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External Link |
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OGAWA Kenjiro
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Papers 【 display / non-display 】
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Effects of the Polyphenols Delphinidin and Rosmarinic Acid on the Inducible Intra-cellular Aggregation of Alpha-Synuclein in Model Neuron Cells.
Yamamoto H, Matsumura R, Nakashima M, Adachi M, Ogawa K, Hongo K, Mizobata T, Kawata Y
Applied biochemistry and biotechnology 195 ( 7 ) 4134 - 4147 2023.7
Language：English Publishing type：Research paper (scientific journal)
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Blueberry Stem Extract Prevents Lacrimal Hyposecretion in Non-obese Diabetic Mice via Activation of AMPK.
Ogawa K, Ohno Y, Tagashira A, Urata K, Satoh K, Fujimoto N, Sonoda H, Ikeda M, Matsuzaki T, Nishiyama K, Kunitake H, Goto YO, Yamasaki M
In vivo (Athens, Greece) 37 ( 3 ) 1003 - 1015 2023.5
Language：English Publishing type：Research paper (scientific journal)
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Blueberry stem extract and stem active components prevent blue light-emitting diode light-induced retinal photoreceptor cell damage in vitro.
Ogawa K, Urata K, Suzuki Y, Sugamoto K, Goto Y, Nakayama T, Nishiyama K, Kunitake H, Yamasaki M
Bioscience, biotechnology, and biochemistry 87 ( 4 ) 378 - 388 2023.3
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1093/bbb/zbad001
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Blueberry Leaf Extract Prevents Lacrimal Hyposecretion in Sjögren's Syndrome-like Model of Non-obese Diabetic Mice.
Ogawa K, Urata K, Maeda S, Ohno Y, Satoh K, Yamada Y, Suzuki Y, Koga Y, Sugamoto K, Kawaguchi M, Kunitake H, Nishiyama K, Goto YO, Nakayama T, Yamasaki M
In vivo (Athens, Greece) 37 ( 1 ) 149 - 162 2023.1
Language：English Publishing type：Research paper (scientific journal)
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Protective effect of Vaccinium myrtillus L. extract against UVA-induced injury in ARPE-19 cells
Otsu Wataru, Hara Hideaki, Ogawa Kenjiro
Food Science and Technology International, Tokyo advpub ( 0 ) 2023
Language：English Publishing type：Research paper (scientific journal) Publisher：公益社団法人 日本食品科学工学会
Retinal pigment epithelium (RPE) is an essential vision component of the human eye due to its nutritional and functional support to photoreceptors. Age-related macular degeneration (AMD) is a progressive, degenerative retinal disease characterized by RPE loss. Ultraviolet (UV) light exposure induces injurious effects on human eyes by generating excess reactive oxygen species (ROS) and is responsible for photoaging. Bilberry (<i>Vaccinium myrtillus</i> L.) and its extract (VME) are known for their potent antioxidant properties. In the present study, we examined the effect of VME on UVA-induced RPE injury. Using an <i>in vitro</i> system with human RPE (ARPE-19) cells, pretreatment with VME suppressed cell death, mitochondrial superoxide production, and activation of the stress response that occurs following UVA irradiation. Furthermore, VME attenuated rotenone-induced mitochondrial ROS and concomitant reduction in cell viability. Our findings suggest that VME has a protective effect against UVA-induced RPE cell damage.
MISC 【 display / non-display 】
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The involvement of anthocyanin-rich foods in retinal damage. Invited
Ogawa K., Hara H.
Recent Advances in Polyphenol Research 193 - 205 2017
Language：English Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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ビルベリー由来アントシアニンが目に与える機能性―ヒト臨床試験と機能性表示食品― Invited
小川健二郎，原英彰
岐阜薬科大学紀要 65 20 - 27 2016
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution) Publisher：岐阜薬科大学
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網膜障害に対する食品色素成分の有効性（特集 色のもつ多彩な食機能） Invited
小川健二郎，原英彰
Foods & Food Ingredients Journal of Japan 219 ( 2 ) 114 - 125 2014
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)
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アントシアニン（特集 眼科で使えるサプリメント） Invited
小川健二郎，田中潤司，原英彰
眼科 54 ( 7 ) 873 - 886 2012
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal) Publisher：金原出版
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アレルギー疾患とキノコ
沼津工業高等専門学校研究報告
沼津工業高等専門学校研究報告 38 123 - 128 2004
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution)
Grant-in-Aid for Scientific Research 【 display / non-display 】
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涙液分泌機能におけるポリフェノール・パラドックスを脳腸軸から紐解く
Grant number：22K14844 2022.04 - 2025.03
独立行政法人日本学術振興会 科学研究費補助金 若手研究
Authorship：Principal investigator