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Faculty of Medicine School of Medicine Department of Medicine of Sensory and Motor Organs, Orthopedic Surgery |
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Assistant Professor |
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Related SDGs |
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NAGAI Takuya
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Papers 【 display / non-display 】
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Engineered Expression of Hepatocyte Growth Factor Activator Inhibitor-1 (HAI-1) Reduces the Growth of Bladder Cancer Cells. Reviewed
Katayama Y, Akioka T, Kimura S, Fujii M, Nagai T, Kiwaki T, Kawaguchi M, Fukushima T, Sato Y, Mukai S, Kamoto T, Sawada A
Biomedicines 13 ( 4 ) 2025.4
Authorship：Lead author, Last author, Corresponding author Language：English Publishing type：Research paper (scientific journal)
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Shimura A., Nojiri H., Ishijima M., Moridaira H., Arai H., Takada S., Yamada K., Kondo N., Morino T., Nakamura E., Tomori M., Otani K., Akeda K., Nagai T., Toyoda H., Ito K., Katayanagi J., Taneichi H.
Spine 50 ( 3 ) 179 - 186 2025.2
Authorship：Lead author, Last author, Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Spine
Study Design. This was a multicenter retrospective cohort study. Objective. We investigated the incidence of postoperative shoulder imbalance (PSI) and its risk factors in patients with Lenke types 1 and 2 scoliosis corrected using vertebral coplanar alignment (VCA). Summary of Background Data. PSI in scoliosis affects patient quality of life. While other correction methods have reported a high correction rate for the main thoracic curve (MTC) in relation to PSI, this correlation has not been confirmed for the VCA technique. Materials and Methods. We studied 176 patients with Lenke types 1 and 2 scoliosis who underwent posterior corrective fusion surgery using the VCA technique at 11 institutions. At 2 years postoperatively, patients were divided into two groups based on radiographic shoulder height (RSH): PSI- (RSH<2 cm) and PSI+ (RSH ≥2 cm) groups. We analyzed the risk factors for PSI. Results. The overall incidence of PSI 2 years postoperatively was 11.4% (20/176), with 9.2% (11/119) and 15.8% (9/57) in patients with Lenke types 1 and 2, respectively. Contrary to a previous study, a high MTC correction rate did not emerge as a risk factor for PSI. Instead, preoperative left shoulder elevation, low postoperative thoracic kyphosis, greater T1 tilt, and high apical vertebral body-to-rib ratio were associated with PSI in patients with Lenke type 1. Preoperative left shoulder elevation and a low postoperative proximal thoracic curve (PTC) correction rate were identified as risk factors for PSI in patients with Lenke type 2. Conclusion. Our results suggest that proper PTC correction, rather than compromising MTC correction, may help prevent PSI in the VCA technique. This method is particularly advantageous for addressing Lenke type 1 scoliosis and yields favorable outcomes in shoulder balance. Patients with preoperative left shoulder elevation, especially Lenke type 2, are at high risk of developing PSI. Level of Evidence. Level 4.
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Shimura Arihisa, Nojiri Hidetoshi, Moridaira Hiroshi, Arai Hidekazu, Takada Satoshi, Yamada Katsutaka, Kondo Naoya, Morino Tadao, Nakamura Eiichiro, Tomori Masaki, Otani Kazuyuki, Akeda Koji, Nagai Takuya, Toyoda Hiromitsu, Ito Kenyu, Katayanagi Junya, Taneichi Hiroshi
Journal of Spine Research 16 ( 1 ) 39 - 47 2025.1
Authorship：Lead author, Last author, Corresponding author Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japanese Society for Spine Surgery and Related Research
<b>Introduction: </b>Postoperative shoulder imbalance (PSI) significantly affects the quality of life of patients with scoliosis. Several studies report the risk factors for PSI; however, the imaging factors that define T1 tilt and RSH motion are unknown, and there are no reports on the magnitude of change in these factors. Herein, we investigated the factors influencing radiographic shoulder height (RSH) and T1 tilt in patients who underwent scoliosis correction using the vertebral coplanar alignment (VCA) technique.<b>Methods: </b>In total, 76 patients with Lenke type 1, who underwent posterior spinal fusion using the VCA technique at 11 centers, were included. Correlation coefficients between pre- and post-operative changes in RSH and T1 tilt (ΔRSH and ΔT1 tilt) and changes in other parameters were analyzed.<b>Results: </b>Flexibility of the proximal thoracic curve (PTC) showed a weak negative correlation with ΔRSH. PTC correction rate revealed a weak negative correlation with ΔT1 tilt from preoperative to 2 years postoperative. Change in the main thoracic apical vertebral translation (ΔMT-AVT) indicated a positive weak correlation with ΔRSH from preoperative to immediate postoperative and ΔT1 tilt immediate postoperative and 2 years postoperative.<b>Conclusions: </b>PTC flexibility and correction rate are important for achieving good shoulder balance in Lenke type 1 scoliosis. ΔMT-AVT is the defining factor for ΔRSH and ΔT1 tilt and the marker for intraoperative evaluation to adjust shoulder balance.
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脊椎手術の術中・術後の止血に難渋し発覚した血小板機能異常症の1例
肥後 聖, 比嘉 聖, 濱中 秀昭, 黒木 修司, 永井 琢哉, 日髙 三貴, 高橋 巧, 帖佐 悦男
整形外科と災害外科 73 ( 3 ) 415 - 420 2024.9
Authorship：Lead author, Last author, Corresponding author Language：Japanese Publishing type：Research paper (scientific journal) Publisher：西日本整形・災害外科学会
【はじめに】凝固能の評価のために手術前には凝固能検査を行うことが一般的である．今回，脊椎手術の術中・術後の止血に難渋し発覚した血小板機能異常症の1例を経験したため報告する．【症例】74歳男性，間欠跛行を主訴に当院受診され，MRI検査にてL3/4/5に変性すべり症に伴う腰部脊柱管狭窄症を認めた．腰椎固定術を施行し，術中に軟部組織からの出血が多く止血に難渋し，また術後ドレーンや創部からの多量の出血を認めた．過去にも当院で腰部脊柱管狭窄症に対して椎弓切除術施行した際に術後血腫を認め血腫除去術を施行していた．父親も痔核術後に大量出血で逝去した家族歴があるため遺伝性血液凝固異常があると考えられた．精査の結果，遺伝性の血小板機能異常症の診断となった．【考察】脊椎手術の術中・術後の止血に難渋し発覚した血小板機能異常症の1例を経験した．家族歴があり術中術後の止血に難渋する場合は血小板機能異常症を考慮する必要がある．
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Paratesticular cellular angiofibroma: a case report. Reviewed
Murashima T, Kida K, Gi T, Hida T, Fujii M, Nagai T, Takamori H, Mukai S, Sato Y, Kamoto T
Journal of medical case reports 18 ( 1 ) 170 2024.4
Authorship：Lead author, Last author, Corresponding author Language：English Publishing type：Research paper (scientific journal)
MISC 【 display / non-display 】
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上肢 Roos test Invited
永井琢哉、帖佐悦男
関節外科 38 ( 9 ) 104 - 105 2019.9
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media) Publisher：メディカルビュー
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脊椎-胸椎 腹皮反射 Invited
永井琢哉、帖佐悦男
関節外科 37 ( 5 ) 110 - 111 2018.5
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media) Publisher：メディカルビュー
Presentations 【 display / non-display 】
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Col2A1異常に関連した胸椎後側弯症の1例
永井琢哉、黒木修司、比嘉聖、高橋巧、松本尊行、帖佐悦男
第39回九州小児整形外科集談会 2024.1.13
Event date： 2024.1.13
Presentation type：Oral presentation (general)
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思春期特発性側弯症手術において術前ＣＴは術中の回旋の指標となるか？
永井琢哉、比嘉聖、黒木智文、高橋巧、帖佐悦男
第57回日本側弯症学会学術集会 2023.11.11
Event date： 2023.11.10 - 2023.11.11
Presentation type：Oral presentation (general)
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Lumber modifier BまたはC胸椎特発性側弯症に対する選択的胸椎固定術におけるLIV -サブタイプ別の解析-
森平泰、高田知史、山田勝崇、内野洋介、野尻英俊、志村有永、村上裕介、明田浩司、片柳順也、友利正樹、都島幹人、中村英一郎、永井琢哉、大谷和之、種市洋
第57回日本側弯症学会学術集会 2023.11.11
Event date： 2023.11.10 - 2023.11.11
Presentation type：Oral presentation (general)
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胸腰椎ダブルカーブを有する特発性側弯症に対する術式の検討-後方単独と前後合併の比較-
高田知史、森平泰、山田勝崇、内野洋介、野尻英俊、志村有永、村上裕介、明田浩司、片柳順也、友利正樹、都島幹人、中村英一郎、永井琢哉、大谷和之、種市洋
第57回日本側弯症学会学術集会 2023.11.10
Event date： 2023.11.10 - 2023.11.11
Presentation type：Oral presentation (general)
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Coplanar法におけるロッドの直径や材質による治療成績の検討
村上裕介、森野忠夫、森平泰、高田知史、山田勝崇、内野洋介、野尻英俊、志村有永、明田浩司、片柳順也、友利正樹、都島幹人、中村英一郎、永井琢哉、大谷和之
第57回日本側弯症学会学術集会 2023.11.10
Event date： 2023.11.10 - 2023.11.11
Presentation type：Oral presentation (general)