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Faculty of Medicine College Hospital Cardiovascular surgery |
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SAKAGUCHI Shuhe
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Papers 【 display / non-display 】
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Rapidly expanding Stanford type B aortic dissection associated with coarctation of the aorta in Turner syndrome Reviewed
Shuhei Sakaguchi
Discover Medicine 2026.3
Authorship：Lead author Publishing type：Research paper (scientific journal)
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Tsuda Yuki, Arinaga Koichi, Shuto Takashi, Sonoda Hiromichi, Matsumoto Kazuhisa, Sakaguchi Shuhei, Kuwahara Go, Eto Masataka, Takaki Jun, Inafuku Hitoshi, Takamatsu Masanori, Matsumaru Ichiro, Takagi Kazuyoshi, Kawashima Takayuki, Ushijima Tomoki, Kanda Hideaki, Nakamura Kunihide, Teratani Hiromitsu, Yasutsune Toru, Yoshinaga Takashi, Kise Yuya, Morokuma Hiroyuki, Eishi Kiyoyuki, Miura Takashi, Kamohara Keiji, Furukawa Kojiro, Fukui Toshihiro, Nishimura Yosuke, Wada Hideichi, Furukawa Koji, Soga Yoshiharu, Shiose Akira, Miyamoto Shinji, Tayama Eiki, Fujino Yoshihisa, Otsuji Yutaka, Kataoka Masaharu, on behalf of the ASPIRIN-Trial Investigators
Circulation Journal advpub ( 0 ) 2026.1
Language：English Publishing type：Research paper (scientific journal) Publisher：The Japanese Circulation Society
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Tsuda Yuki, Arinaga Koichi, Shuto Takashi, Sonoda Hiromichi, Matsumoto Kazuhisa, Sakaguchi Shuhei, Kuwahara Go, Eto Masataka, Takaki Jun, Inafuku Hitoshi, Takamatsu Masanori, Matsumaru Ichiro, Takagi Kazuyoshi, Kawashima Takayuki, Ushijima Tomoki, Kanda Hideaki, Nakamura Kunihide, Teratani Hiromitsu, Yasutsune Toru, Yoshinaga Takashi, Kise Yuya, Morokuma Hiroyuki, Eishi Kiyoyuki, Miura Takashi, Kamohara Keiji, Furukawa Kojiro, Fukui Toshihiro, Nishimura Yosuke, Wada Hideichi, Furukawa Koji, Soga Yoshiharu, Shiose Akira, Miyamoto Shinji, Tayama Eiki, Fujino Yoshihisa, Otsuji Yutaka, Kataoka Masaharu, on behalf of the ASPIRIN-Trial Investigators
Circulation Journal advpub ( 0 ) 2026.1
Language：English Publishing type：Research paper (scientific journal) Publisher：The Japanese Circulation Society
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Anomalous Left Circumflex Artery in Valve Interventions: Surgical and Transcatheter Challenges Reviewed
Furukawa K., Ishii H., Sakaguchi S., Mori K., Iwasaki A., Meiri R.
Annals of Thoracic Surgery 2026
Language：English Publishing type：Research paper (scientific journal) Publisher：Annals of Thoracic Surgery
Background Anomalous origin of the left circumflex coronary artery (AOLCX) with a retroaortic course is at risk of compression during valve interventions. Although AOLCX is typically benign, iatrogenic injury can cause catastrophic ischemia. As transcatheter aortic valve replacement (TAVR) expands to lower-risk populations, understanding mechanisms of injury in both surgical and transcatheter settings is becoming crucial. Methods A narrative review was performed focusing on anatomic risks, injury mechanisms, and management of AOLCX. Forty-five relevant publications were synthesized to integrate technical and anatomic evidence. Results Left circumflex artery compromise is determined by the vessel’s proximity to the aortic and mitral annuli. In surgery, deep sutures and prosthetic rings are the primary causes. In TAVR, mechanisms involve retroaortic compression and ostial occlusion, necessitating preprocedural assessment of coronary height, sinus dimensions, calcification, and annular proximity. Preventive strategies include surgical mobilization, prophylactic bypass, and guidewire protection. Bailout strategies include bypass and emergency stenting. For aortic stenosis, procedure selection between surgery and TAVR should be individualized on the basis of age, calcification, and anatomic metrics. Late complications such as delayed coronary obstruction necessitate longitudinal surveillance. Conclusions Preprocedural computed tomographic angiography is essential to quantify anatomic risk. A heart team approach is required to select the optimal intervention and implement mechanism-specific protection. Long-term clinical and imaging surveillance is warranted to prevent both acute and delayed left circumflex artery compromise.
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The Role of Left Ventricular Reconstruction in Ischemic Cardiomyopathy Reviewed
Furukawa Koji, Sakaguchi Shuhei, Mori Kousuke
Journal of Coronary Artery Disease 31 ( 3 ) 98 - 105 2025.9
Language：English Publishing type：Research paper (scientific journal) Publisher：特定非営利活動法人 日本冠疾患学会
We review the relevant literature and our own experience to identify cases in which left ventricular reconstruction (LVR) has been successful, particularly for ischemic cardiomyopathy (ICM). Despite substantial advances in medical and device therapies, surgical treatment of ICM remains important. In this context, LVR for ICM is expected to play a complementary role between heart transplantation or ventricular assist device therapy and surgical treatments such as coronary artery bypass surgery. However, the number of LVRs performed has decreased. This may be because of the lack of well-established cases of successful LVR. Although a good outcome can be expected if the left ventricular (LV) volume is controlled after LVR, it is difficult to identify surgical responders based on preoperative LV volume. Here, we focused on the LV diastolic function, assessed by the echocardiographic mitral inflow waveform ratio (E/A ratio), as an index of the degree of progression of LV remodeling and examined the outcomes of LVR. The preserved LV diastolic function group (E/A ratio < 2) had significantly better outcomes than the impaired LV diastolic function group. The relationship between the degree of LV diastolic function and the efficacy of LVR has recently been investigated. Additionally, LVR has evolved from the resection of ventricular aneurysms to the isolation of the infarct area, reduction of LV volume, and restoration of the normal conical structure of the left ventricle, with promising results. Therefore, selective LVR is an option for HF treatment of heart failure.
DOI： 10.7793/jcad.31.006
Presentations 【 display / non-display 】
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Very long-term outcome of AVR with mechanical valve for under the age of sixty International conference
Shuhei Sakaguchi
The 33rd Annual Meeting of the Asian Society for Cardiovascular and Thoracic Surgery
Event date： 2025.5.14 - 2025.5.17
Language：English Presentation type：Oral presentation (general)
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Acute Stanford type B aortic dissection with rapid expansion associated with aortic coarctation and Turner syndrome: a case report International conference
Shuhei Sakaguchi
2024 STS-ASCVTS Aortic summit
Event date： 2024.11.14 - 2024.11.16
Presentation type：Oral presentation (general)
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The actin-organizing formin protein Fhod3 plays a crucial role in sarcomere morphology in mouse postnatal cardiomyocytes
Shuhei Sakaguchi
The 76th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery 2023.10.21
Event date： 2023.10.18 - 2023.10.21
Language：Japanese Presentation type：Oral presentation (general)
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Accessory mitral valve tissue: A surgical case of left ventricular outflow tract obstruction
Shuhei Sakaguchi
The 53th Annual Meeting of the Japanese Society for Cardiovascular Surgery 2023.3.24
Event date： 2023.3.23 - 2023.3.25
Language：Japanese Presentation type：Oral presentation (general)
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Outcomes of surgery for Coarctation of the Aorta in adolescents and adults
Shuhei Sakaguchi
The 75th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery 2022.10.6
Event date： 2022.10.5 - 2022.10.8
Language：Japanese Presentation type：Oral presentation (general)
Grant-in-Aid for Scientific Research 【 display / non-display 】
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近赤外ハイパースペクトラルイメージングを用いた心臓刺激伝導系可視化技術の創出
Grant number：25K11892 2025.04 - 2028.03
独立行政法人日本学術振興会 科学研究費基金 基盤研究(C)
Authorship：Principal investigator
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近赤外ボクセル分光による非染色三次元解剖構造描出法の創成
Grant number：25K03501 2025.04 - 2028.03
独立行政法人日本学術振興会 科学研究費基金 基盤研究(B)
Authorship：Coinvestigator(s)
Available Technology 【 display / non-display 】
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先天性および後天性不全心筋における細胞骨格制御分子発現の生化学・組織学的検討
未熟心筋２核化の分子メカニズムの解明Home Page： 宮崎大学医学部 外科学講座 心臓血管外科分野
Related fields where technical consultation is available：心臓血管外科手術に関わる臨床データ収集、臨床サンプル収集
細胞骨格制御分子に関連したモデルマウス作成Message：臨床と基礎の垣根を超えた研究を行なっております。ご興味のある方はぜひご連絡ください。