SAKAGUCHI Shuhe

写真a

Affiliation

Faculty of Medicine College Hospital Cardiovascular surgery

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Papers 【 display / non-display

  • Single-Stage Surgical Treatment of Acute Type A Aortic Dissection and Blunt Abdominal Trauma: A Case Report

    Taniguchi Tomoaki, Furukawa Koji, Ishii Hirohito, Kawagoe Katsuya, Sakaguchi Shuhei, Meiri Risa

    Annals of Vascular Diseases   16 ( 3 )   238 - 241   2023.9

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:The Editorial Committee of Annals of Vascular Diseases  

    DOI: 10.3400/avd.cr.23-00017

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  • Successful Surgical Repair of Type A Acute Aortic Dissection in a Patient with Vascular Ehlers–Danlos Syndrome

    Mori Kousuke, Ishii Hirohito, Sakaguchi Shuhei, Sakurahara Daichi, Iwasaki Ayaka, Furukawa Koji

    Annals of Vascular Diseases   15 ( 1 )   58 - 61   2022.3

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:The Editorial Committee of Annals of Vascular Diseases  

    DOI: 10.3400/avd.cr.21-00122

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  • A case of aorto-esophageal fistula after arch aortic replacement rescued by esophagectomy and reconstruction with omental flap

    Uchise Yukako, Tashiro Kousei, Munakata Shun, Kitamura Eiji, Hamada Roko, Kawano Fumiaki, Takeno Shinsuke, Mori Kousuke, Sakaguchi Shuhei, Ishii Hirohito, Furukawa Koji, Nanashima Atsushi

    Japanese Journal of Acute Care Surgery   advpub ( 0 )   95 - 99   2022

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Japanese Society for the Acute Care Surgery  

    A 73 y.o.-male underwent the arch aortic replacement for type A acute aortic dissection. Two years after operation, the computed tomography showed the rupture of thoracic aortic aneurysm and thoracic endovascular aortic repair (TEVAR) was urgently performed. Aorto-esophageal fistula (AEF) subsequently occurred at day 5 after TEVAR. Therefore, we urgently performed esophagectomy under right thoracotomy with accompanied fistulectomy, followed by omentopexy and esophageal reconstruction using gastric conduit 12 days later. To secure AEF patients, the immediate bleeding and infectious control is required. Although urgent artificial blood vessel replacement with esophagectomy with fistulectomy of AEF is desirable, the strategy of surgical intervention depends on the patient’s organ functions or systemic status. Omentopexy is an effective option to reinforce the postoperative infectious control and, additionally, the intraoperative ICG fluorescence angiography may improve to evaluate the omental vascularity by our experience.

    DOI: 10.50840/jjacs.12-5

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  • Influence of preoperative right ventricular function on left ventricular remodeling and survival after subvalvular repair for functional mitral regurgitation.

    Furukawa K, Yano M, Ishii H, Sakaguchi S, Mori K, Nishimura M, Nakamura K

    Heart and vessels   36 ( 7 )   1064 - 1071   2021.1

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Heart and Vessels  

    Objectives: The objective of this study was to analyze our surgical experiences with mitral valve plasty (MVP) combined with subvalvular procedures (SVPs) for functional mitral regurgitation (FMR) and to determine which preoperative factors affected clinical outcomes. Methods: This study retrospectively analyzed 33 patients who underwent MVP combined with SVPs for FMR with a left ventricular ejection fraction lower than 40% and advanced remodeled left ventricles. The mean follow-up period was 49 ± 33 months. Results: The preoperative mean right ventricular fractional area change (RVFAC) used to quantify right ventricular (RV) systolic function was 26 ± 11%. Sixteen patients (48%) had an RVFAC < 26%. One patient died during hospital stay, and nine more patients died of cardiac causes during follow-up. The 3- and 5-year rates of freedom from cardiac-related mortality were 78% and 68%, respectively. RVFAC was the significant predictor of cardiac-related mortality in a univariate analysis (risk ratio [RR] = 0.92, 95% confidence interval [CI] 0.85–0.99, p = 0.03) and demonstrated a non-significant tendency to predict cardiac-related mortality in the Cox multivariate analysis (RR = 0.94, 95% CI 0.86–1.003, p = 0.08). Continued reverse left ventricular remodeling was associated with an RVFAC ≥ 26%. At 3 years, there was also a significant difference in survival rates of cardiac-related mortality between patients with an RVFAC ≥ 26% and < 26% (94% vs. 61%; p = 0.03). Conclusions: Preoperative RV function affected left ventricular remodeling and cardiac-related mortality after MV surgery. MVP combined with SVPs for FMR provided promising results for patients without severe RV dysfunction.

    DOI: 10.1007/s00380-021-01774-6

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  • Clinical Outcomes of a Customized Mitral Valve Plasty for Functional Mitral Regurgitation with a Low Ejection Fraction and Implications for Preoperative Right Ventricular Function

    Furukawa Koji, Yano Mitsuhiro, Ishii Hirohito, Sakaguchi Shuhei, Mori Kousuke, Nishimura Masanori, Nakamura Kunihide

    Annals of Thoracic and Cardiovascular Surgery   27 ( 1 )   32 - 40   2020.6

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    Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery  

    Purpose: To evaluate clinical outcomes of customized mitral valve plasty (MVP) for the treatment of functional mitral regurgitation (FMR) with a low ejection fraction (EF) and to determine which preoperative factors affected the clinical outcome.Methods and Results: MVP was adjusted according to the degree of left ventricle (LV) remodeling. We performed mitral annuloplasty (MAP) alone in 14 patients and added subvalvular procedures (SVPs) in 22 patients at a high risk of recurrent MR. During follow-up, reverse LV remodeling was obtained and the 3-year and 5-year non-recurrence rates of MR grade ≥2 were 94% and 89%, respectively. Two patients died during their hospital stay, and four more patients died of cardiac causes during follow-up. The 3-year and 5-year rates of freedom from cardiac-related mortality were 86% and 81%, respectively; no significant difference was observed between the two treatment groups. Right ventricular fractional area change (RVFAC) was a significant predictor of cardiac mortality. Patients with an RVFAC of <26% had significantly poorer cardiac-related mortality (71% at 3 years) than those with an RVFAC of ≥26% (95% at 3 years).Conclusion: Customized MVP provided durable mitral competence and reverse LV remodeling. Preoperative RV function was associated with cardiac-related mortality.

    DOI: 10.5761/atcs.oa.20-00035

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Presentations 【 display / non-display

  • The actin-organizing formin protein Fhod3 plays a crucial role in sarcomere morphology in mouse postnatal cardiomyocytes

    Shuhei Sakaguchi

    The 76th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery  2023.10.21 

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    Event date: 2023.10.18 - 2023.10.21

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Accessory mitral valve tissue: A surgical case of left ventricular outflow tract obstruction

    Shuhei Sakaguchi

    The 53th Annual Meeting of the Japanese Society for Cardiovascular Surgery  2023.3.24 

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    Event date: 2023.3.23 - 2023.3.25

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Outcomes of surgery for Coarctation of the Aorta in adolescents and adults

    Shuhei Sakaguchi

    The 75th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery  2022.10.6 

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    Event date: 2022.10.5 - 2022.10.8

    Language:Japanese   Presentation type:Oral presentation (general)  

  • Stroke after surgical AVR in young patients and future prosthetic valve selection

    Shuhei Sakaguchi

    The 52nd Annual Meeting of the Japanese Society for Cardiovascular Surgery  2022.3 

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    Event date: 2022.3.3 - 2022.3.5

    Language:English   Presentation type:Oral presentation (general)  

  • Long-term outcome of surgical AVR for under the age of 60: single-center study over a 25-year period

    Shuhei Sakaguchi

    The 74th Annual Scientific Meeting of the Japanese Association for Thoracic Surgery  2021.11 

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    Event date: 2021.10.31 - 2021.11.3

    Language:English   Presentation type:Oral presentation (general)  

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