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医学部 医学科 内科学講座循環器・腎臓内科学分野 |
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准教授 |
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論文 【 表示 ／ 非表示 】
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Hiroki Tanaka, Yunosuke Matsuura, Kinuko Yamamoto, Soichi Komaki, Masashi Yamaguchi, Kohei Moribayashi, Takeshi Ideguchi, Michikazu Nakai, Toshihiro Tsuruda, Koichi Kaikita
Circulation Reports 2025年12月
担当区分：責任著者 記述言語：英語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Japanese Circulation Society
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Left Ventricular Outflow Tract Obstruction Due to Accessory Mitral Valve Tissue: An Unusual Systolic Murmur in an Elderly Patient. 査読あり 国際誌
Kohei Kurogi, Tomoaki Taniguchi, Yunosuke Matsuura, Yoshimasa Yamamura, Nozomi Watanabe, Koji Furukawa, Koichi Kaikita
JACC. Case reports 106288 - 106288 2025年12月
担当区分：責任著者 記述言語：英語 掲載種別：研究論文（学術雑誌）
BACKGROUND: Accessory mitral valve tissue (AMVT) is a rare congenital anomaly that is typically diagnosed during childhood and overlooked in elderly patients presenting with left ventricular outflow tract (LVOT) obstruction. CASE SUMMARY: A 73-year-old man presented with exertional presyncope and a systolic murmur. Transthoracic echocardiography revealed a mobile sac-like structure protruding into the LVOT, causing a 74 mm Hg gradient despite a normal aortic valve. Multimodal imaging confirmed a type IIB2 AMVT with dynamic prolapse. Surgical resection and histological analysis confirmed valve-like tissues. At the 3-year follow-up, the patient had remained asymptomatic with no recurrence. DISCUSSION: This case shows that AMVT, although congenital, can rarely present in elderly individuals. A crescendo systolic murmur with beat-to-beat variability aids diagnosis. Multimodal imaging is critical for diagnosis and surgical planning. Prompt excision and careful perioperative management ensure durable relief and favorable long-term outcomes. TAKE-HOME MESSAGES: AMVT, although congenital, can present as LVOT obstruction, even in elderly patients. A crescendo systolic murmur with beat-to-beat variability is a clinical sign of dynamic obstruction caused by AMVT.
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Response to Letter - referencing JCCT-D-25-426 ''Integrating radiomics into coronary computed tomography angiography: Enhancing prognostic value after percutaneous coronary intervention'' by Macit Kalçık et al. 招待あり 査読あり 国際誌
Yunosuke Matsuura, Soichi Komaki, Yoshikazu Uchiyama, Koichi Kaikita
Journal of cardiovascular computed tomography 2025年10月
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Coronary computed tomography angiography radiomics for predicting major adverse cardiovascular events after percutaneous coronary interventions 査読あり
Soichi Komaki, Yunosuke Matsuura, Yoshikazu Uchiyama, Shintaro Izumoto, Hiroki Tanaka, Masashi Yamaguchi, Kohei Moribayashi, Kazumasa Kurogi, Nobuyasu Yamamoto, Michikazu Nakai, Koichi Kaikita
Journal of Cardiovascular Computed Tomography 2025年7月
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Akiko Uchida, Yunosuke Matsuura, Shuhei Sakaguchi, Koji Furukawa, Koichi Kaikita
European Heart Journal - Case Reports 2025年6月
担当区分：責任著者 記述言語：英語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Oxford University Press (OUP)
Abstract
Background
Migraines are commonly associated with cardiovascular diseases. Notable associations are found between migraines and right-to-left shunts (RLS); however, the direct causality between them remains controversial.
Case Summary
A 55-year-old woman with persistent hypoxemia and over 30 years of history of migraines with aura was referred for precise evaluation. Hypoxemia-related symptoms were limited, and physical examinations showed normal findings, with no evidence of pulmonary compromise on imaging or function tests. Contrast-enhanced computed tomography (CT) and venography revealed congenital anomalies of systemic venous return: the right superior vena cava (RSVC) draining into the left atrium (LA) and the left superior vena cava draining into the right atrium via the coronary sinus (PLSVC). Echocardiography did not find the RSVC draining into the LA. Concerning the risk of paradoxical embolization, RSVC was surgically ligated, successfully closing the shunt. Postoperatively, hypoxemia normalized, and the patient experienced an unexpected improvement in migraine symptoms, with a Headache Impact Test (HIT)-6 score dropping from 65 (indicating severe headache impact) to 38 (indicating minimal impact on daily life). Five years post-surgery, migraine symptoms are under control in the absence of specific medications.
Discussion
RSVC drainage into the LA represents chronic hypoxemia, but symptoms are commonly limited and may not be detected until serious brain complications develop. However, this rare congenital anomaly may, at times, be causally related to migraines with aura.
書籍等出版物 【 表示 ／ 非表示 】
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最新 MINOCA/INOCA の診断と治療
松浦祐之介, 海北幸一（ 担当： 分担執筆 , 範囲: 1. MINOCAの診断 (4. 冠攣縮の診断), 2. INOCAの診断(3. 冠攣縮性狭心症の診断)）
日本医事新報社 2025年10月
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内科臨床誌 メディチーナ Vol.60 No.13 特集 : 一般医家のためのDOAC時代の心房細動診療
小牧聡一, 松浦祐之介, 海北幸一（ 担当： 分担執筆 , 範囲: 18. PCI後の抗血栓療法をどうする？）
医学書院 2023年12月
MISC 【 表示 ／ 非表示 】
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Association between angiopoietin-like protein 3 and frailty in cardiovascular disease patients
H Tanaka, Y Matsuura, K Yamamoto, S Komaki, M Yamaguchi, K Moribayashi, T Ideguchi, T Tsuruda, K Kaikita
European Heart Journal, Volume 46, Issue Supplement_1, November 2025, ehaf784.4076, 2025年11月
掲載種別：速報，短報，研究ノート等（学術雑誌）
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Unique amino acid profile and prognostic significance of the Fischer ratio in end-stage kidney disease patients with cardiovascular disease
K Moribayashi, Y Matsuura, K Yamamoto, H Tanaka, S Komaki, M Yamaguchi, T Ideguchi, T Tsuruda, K Kaikita
European Heart Journal, Volume 46, Issue Supplement_1, November 2025, ehaf784.4188, 2025年11月
掲載種別：速報，短報，研究ノート等（学術雑誌）
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Renal blood flow response after transcatheter aortic valve replacement for severe aortic stenosis: a longitudinal renal artery doppler ultrasound study
N Kodama, Y Matsuura, K Yamamoto, H Tanaka, S Komaki, M Yamaguchi, K Moribayashi, T Ideguchi, T Tsuruda, K Kaikita
European Heart Journal, Volume 46, Issue Supplement_1, November 2025, ehaf784.2261 2025年11月
掲載種別：速報，短報，研究ノート等（学術雑誌）
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Prognostic predictive value of circulating angiopoietin-like protein 3 in patients with chronic coronary syndrome
H Tanaka, Y Matsuura, K Yamamoto, S Komaki, M Yamaguchi, K Moribayashi, T Ideguchi, T Tsuruda, K Kaikita
European Heart Journal, Volume 46, Issue Supplement_1, November 2025, ehaf784.1632, 2025年11月
掲載種別：速報，短報，研究ノート等（学術雑誌）
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ATTR型心アミロイドーシスにおける右房ストレイン異常の臨床的意義
尾方 美幸, 松浦 祐之介, 伊藤 芽生, 田中 美与, 山口 昌志, 鶴田 敏博, 海北 幸一, 古川 貢之, 渡邉 望
超音波医学 52 ( Suppl. ) S494 - S494 2025年4月
記述言語：日本語 掲載種別：速報，短報，研究ノート等（学術雑誌） 出版者・発行元：(公社)日本超音波医学会
科研費（文科省・学振・厚労省）獲得実績 【 表示 ／ 非表示 】
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健康寿命延伸を見据えた抗血栓療法のための新規出血リスクスコアの開発
研究課題/領域番号：24K11294 2024年04月 - 2027年03月
独立行政法人日本学術振興会 科学研究費基金 基盤研究(C)
担当区分：研究代表者
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末梢血単球の糖代謝モニタリングを用いた糖尿病性動脈硬化進展予防スキームの構築
研究課題/領域番号：20K17121 2020年04月 - 2023年03月
独立行政法人日本学術振興会 科学研究費補助金 若手研究
担当区分：研究代表者