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Affiliation |
Faculty of Medicine School of Medicine Department of community Pediatrics and Support Raising Next-Generation |
KODAMA Yoshihiko
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Research Areas 【 display / non-display 】
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Life Science / Embryonic medicine and pediatrics
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Life Science / Cardiology
Papers 【 display / non-display 】
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Novel splice site variant of TMEM38B in osteogenesis imperfecta type XIV
Kodama Y., Meiri S., Asada T., Matsuyama M., Makino S., Iwai M., Yamaguchi M., Moritake H.
Human Genome Variation 10 ( 1 ) 25 2023.12
Authorship：Lead author, Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Human Genome Variation
Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by brittle bones. In this case report, we describe a patient who suffered from OI type XIV with a novel splice site variant in the TMEM38B gene. Further research is needed to better understand the relationship between the phenotype of OI type XIV and this variant.
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Suzuki S., Kodama Y., Kuraoka A., Hara T., Ishikawa Y., Nakano T., Sagawa K.
Pediatric Cardiology 2023.10
Authorship：Corresponding author Publishing type：Research paper (scientific journal) Publisher：Pediatric Cardiology
Postoperative chylothorax in patients with congenital heart diseases (CHD) results in poor outcomes if anatomical and functional abnormalities of the lymphatic system are present. While these abnormalities are typically diagnosed by intranodal lymphangiography and dynamic contrast magnetic resonance lymphangiography, the usefulness of lymphoscintigraphy in these patients has not been evaluated. Between January 2019 and December 2021, 28 lymphoscintigraphies were performed in our institution for investigating prolonged pleural effusion after cardiac surgery. The images were assessed by three board-certified pediatric cardiologists retrospectively to determine the likelihood of a central lymphatic flow disorder. The likelihood was scored (range 1–3) based on structural abnormalities and congestive flow in the lymphatic system. Those scores were summed and the likelihood was categorized as low to intermediate (< 8 points) or high (8 or 9 points). Median age at lymphoscintigraphy was 129 days (IQR, 41–412 days), it was performed at a median of 22 days (IQR, 17–43) after surgery, and median score was 6 points (IQR, 4–7.5). Kendall’s coefficient of concordance (0.867; p < 0.05) indicated high inter-rater reliability. Overall survival at 6 months after surgery was 92.5% in the low-to-intermediate group but 68.6% in the high group (p < 0.05), and duration of postoperative thoracic drainage was 27 and 58 days, respectively (p < 0.05). Lymphatic abnormalities detected by lymphoscintigraphy were associated with poorer outcomes. Lymphoscintigraphy was thought to be useful in assessing anatomic and functional lymphatic abnormalities, despite its minimal invasiveness.
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Pulmonary Artery Development Over Time in Severe Ebstein Anomaly. Reviewed
Shirozu H, Kodama Y, Kuraoka A, Ishikawa Y, Nakano T, Kado H, Sagawa K.
Pediatric Cardiology 2022.10
Authorship：Corresponding author Publishing type：Research paper (scientific journal)
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Hemodynamic Characteristics After Fontan Procedure in Patients with Down's Syndrome. Reviewed
Otsuka M, Kodama Y, Kuraoka A, Ishikawa Y, Nakamura M, Nakano T, Kado H, Umemoto S, Ishikita A, Sakamoto I, Ide T, Tsutsui H, Sagawa K.
Pediatric Cardiology 2022.2
Authorship：Corresponding author Publishing type：Research paper (scientific journal)
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The complication of Fontan procedure using extracardiac conduit Reviewed
Kodama Y, Oda S, Umemoto S, Kuraoka A, Ishikawa Y, Nakamura M, Nakano T, Kado H, Sakamoto I, Ohtani K, Ide T, Tsutsui H, Sagawa K
International Journal of Cardiology Congenital Heart Disease 2021.8
Authorship：Lead author, Corresponding author Publishing type：Research paper (scientific journal)
MISC 【 display / non-display 】
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【成人移行支援の二面性】成人医療との連携の場 小児科と成人診療科との連携 異なる病院間での連携． Invited
兒玉 祥彦
小児内科 2021.8
Authorship：Lead author Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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【小児の症候群】循環器 Bland-White-Garland症候群(左冠動脈肺動脈起始症) Invited
兒玉 祥彦, 石川 司朗
小児科診療 2016.10
Authorship：Lead author Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
Awards 【 display / non-display 】
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第56回日本小児循環器学会 会長賞
2020.10 日本小児循環器学会
兒玉 祥彦
Award type：Award from Japanese society, conference, symposium, etc.
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第53回欧州小児循環器学会 YIA賞
2019.5 欧州小児循環器学会（AEPC）
兒玉 祥彦
Award type：International academic award (Japan or overseas)
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第21回日本心不全学会 YIA最優秀賞
2017.10 日本心不全学会
兒玉 祥彦
Award type：Award from Japanese society, conference, symposium, etc.
Grant-in-Aid for Scientific Research 【 display / non-display 】
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深層学習を用いた複雑心奇形患者の心室機能推定プログラムの開発
Grant number：23K07480 2023.04 - 2026.03
独立行政法人日本学術振興会 科学研究費補助金 基盤研究(C)
Authorship：Principal investigator
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先天性骨系統疾患の医療水準と患者QOLの向上を目的とした研究
Grant number：22FC1012 2022.04 - 2025.03
厚生労働省 厚生科研 厚生労働科学研究費補助金 難治性疾患政策研究事業
Authorship：Coinvestigator(s)
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フォンタン術後青年期患者の予後改善を目的とした安全で新しい運動管理プランの開発
Grant number：20K08417 2020.04 - 2024.03
独立行政法人日本学術振興会 科学研究費補助金 基盤研究(C)
Authorship：Principal investigator