|
Affiliation |
Faculty of Medicine Center for the Support and Development of Medical Professionals Department of Clinical Education |
|
Related SDGs |
|
MEIRI Satoru
|
|
|
Papers 【 display / non-display 】
-
河野 文彰, 千代反田 顕, 中目 和彦, 明利 聡瑠, 福島 剛, 佐藤 勇一郎, 山口 秀樹, 池ノ上 実, 宗像 駿, 樋口 和宏, 武野 慎祐, 七島 篤志
Endocrinology Diabetes and Metabolism Case Reports 2025 ( 2 ) 2025.5
Language：English Publishing type：Research paper (scientific journal) Publisher：Bioscientifica
Summary
Spindle epithelial tumor with thymic-like elements (SETTLE) is an extremely rare tumor that occurs primarily in the thyroid gland. Histologically, SETTLE is characterized by the presence of spindle-shaped epithelial cells and glandular structures. However, it is known that diagnosis via fine-needle aspiration cytology can be challenging. SETTLE predominantly occurs in younger individuals and has a less favorable prognosis compared to differentiated thyroid carcinoma. Therefore, ensuring accurate diagnosis and appropriate treatment is crucial. We encountered a case of spindle epithelial tumor with thymus-like differentiation in a 10-year-old patient for whom the preoperative diagnosis was successfully established through fine-needle aspiration cytology, which facilitated appropriate surgical resection. Comprehensive histopathological examination and immunohistochemical analysis are essential to ensure appropriate management and surveillance of SETTLE.
Learning points
A rare thyroid tumor, spindle epithelial tumor with thymic-like elements (SETTLE), was diagnosed preoperatively and treated surgically.
SETTLE presents with characteristic histological features that must be recognized for accurate diagnosis. In addition, diagnosis through cytology is often challenging.
The primary treatment for SETTLE is surgical intervention as radiotherapy and pharmacological treatments are generally not expected to be highly effective.
Radical resection is the only effective treatment, making the selection of the surgical procedure according to the stage of the disease essential. -
Citrin Deficiency with Elevated Galactose Levels Managed by Protein Hydrolysate and Medium-Chain Triglyceride Formula Reviewed
Satoru Meiri
Bulletin on Special Formula ( 60 ) 49 - 52 2025.2
Authorship：Lead author Language：Japanese Publishing type：Case report
Grant-in-Aid for Scientific Research 【 display / non-display 】
-
新生児スクリーニングを契機に発見される家系内ファブリー病症例のコホート研究
Grant number：25K13371 2025.04 - 2028.03
独立行政法人日本学術振興会 科学研究費基金 基盤研究(C)
Authorship：Coinvestigator(s)