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Affiliation |
Faculty of Medicine School of Medicine Department of Clinical Neuroscience, Neurosurgery |
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Professor |
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Related SDGs |
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OKITA Yoshiko
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Papers 【 display / non-display 】
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TAMURA Mitsuru, YAMASHITA Shinji, KAWANO Tomoki, KOMAKI Satoru, TSUKINO Takeru, KOJIMA Koutarou, MAEDA Kenichi, KIMOTO Yasuhiro, KADOTA Yoshihito, AZUMA Minako, OKITA Yoshiko
NMC Case Report Journal 13 ( 0 ) 69 - 75 2026.12
Language：English Publishing type：Research paper (scientific journal) Publisher：The Japan Neurosurgical Society
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Okuyama H., Yokogami K., Yamashita S., Okita Y.
Human Pathology Reports 43 2026.3
Publishing type：Research paper (scientific journal) Publisher：Human Pathology Reports
Currarino syndrome is a rare congenital disorder characterized by a triad of presacral mass, sacral agenesis, and anorectal malformation. We report a case of Currarino syndrome with heterozygous in-frame deletion in homeobox of MNX1 gene. Currarino syndrome is an autosomal-dominant inheritance, and many cases of MNX1 mutations have been reported, but there are no reports of symptomatic with heterozygous in-frame deletions in sporadic cases. We downloaded the MNX1 data from open database ClinVar-NCBI. After adding seven literature reports not included in the database with present case, we re-analyzed the mutation type, location and symptoms. Among 81 cases with gene mutations upstream of homeobox, structural changes in homeobox were observed in 39 of 41 symptomatic cases (95.1%), while in only 1 of 40 asymptomatic cases (2.5%). This finding indicates that structural changes in the homeobox of the MNX1 gene are significantly involved in whether Currarino syndrome becomes symptomatic.
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Accurate classification of ependymomas and medulloblastomas using Raman spectroscopy and pilot transcriptomic profiling. Reviewed International journal
Yuki Kawamoto, Yoshiko Okita, Kenta Temma, Toshiki Kubo, Yasuaki Kumamoto, Yasuhiro Fujii, Keisuke Nishimoto, Reina Utsugi, Chisato Yokota, Ryuichi Hirayama, Noriyuki Kijima, Khoo Hui Ming, Naoki Tani, Satoru Oshino, Naoki Kagawa, Daisuke Motooka, Katsumasa Fujita, Haruhiko Kishima
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 352 127532 - 127532 2026.1
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
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A Rare Case of a Solid Variant Aneurysmal Bone Cyst of the Medial Sphenoid Bone: Clinical Features, Diagnostic Points, and Treatment Reviewed
YAMASHITA Shinji, MATSUMOTO Fumitaka, OKUYAMA Hironobu, OGASAWARA Natsuki, TAMURA Mitsuru, KAWANO Tomoki, YOKOGAMI Kiyotaka, KIWAKI Takumi, FUKUSHIMA Tsuyoshi, SATO Yuichiro, TOMONAGA Takumi, OKITA Yoshiko
NMC Case Report Journal 12 ( 0 ) 369 - 375 2025.12
Language：English Publishing type：Research paper (scientific journal) Publisher：一般社団法人 日本脳神経外科学会
A 5-year-old boy presented to our hospital with ptosis and an abnormal ocular position. Magnetic resonance imaging showed a well-defined mass measuring 20 mm in diameter in the medial sphenoid bone extending to the orbit and compressing the external ocular muscle. The patient underwent total surgical excision and was subsequently diagnosed with a solid variant of aneurysmal bone cyst via molecular integrated diagnosis. Solid variant of aneurysmal bone cyst is an extremely rare subtype of aneurysmal bone cyst, accounting for 0.2% of all primary bone tumors. It is characterized by the absence of a solid cystic component, which is difficult to diagnose via conventional hematoxylin and eosin staining. Molecular analyses revealed that this subtype is also characterized by the rearrangement of <i>USP6</i> and the absence of the H3F3A mutation. This report discusses the clinical features of this extremely rare neoplastic lesion, the importance of an integrated diagnosis, and treatment options.
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KADOTA Yoshihito, ODA Yoshinao, AKIYAMA Yuri, AZUMA Minako, YAMASHITA Atsushi, OKITA Yoshiko, YAMASHITA Shinji, OGURI Nobuyuki, KAWANO Tomoki, AKIZUKI Keiichi, TOMONAGA Takumi, MATSUMOTO Fumitaka
NMC Case Report Journal 12 ( 0 ) 525 - 530 2025.12
Language：English Publishing type：Research paper (scientific journal) Publisher：The Japan Neurosurgical Society
Presentations 【 display / non-display 】
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悪性脳腫瘍の診断と集学的治療
沖田 典子
神戸オンコロジーセミナー 2025.12.11
Event date： 2025.12.11
Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech
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悪性脳腫瘍診療と私なりのリーダーシップ ― 女性が管理職になるということ
沖田 典子
愛知脳神経外科カンファレンス2025 2025.8.7
Event date： 2025.12.6
Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech
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悪性脳腫瘍の診断と集学的治療
沖田 典子
第14回Mt.Tsukuba 2025.11.7
Event date： 2025.11.7
Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech
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KINEVO 900Sが可能にする術者の体格に左右されない脳腫瘍手術
沖田 典子
日本脳神経外科第84回学術集会 2025.10.29
Event date： 2025.10.29 - 2025.11.1
Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech
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少人数医局における脳腫瘍手術の安全管理ー合併症対策の実際と工夫
沖田 典子
日本脳神経外科第84回学術集会 2025.10.30
Event date： 2025.10.29 - 2025.11.1
Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech
Grant-in-Aid for Scientific Research 【 display / non-display 】
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膠芽腫に対する新規治療法の探索を可能とするデジタルツインの基盤技術開発
Grant number：25K22913 2025.04 - 2027.03
独立行政法人日本学術振興会 科学研究費基金 挑戦的研究（萌芽）
Authorship：Coinvestigator(s)
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膠芽腫におけるシングルセルラマン分光法の確立による腫瘍細胞特性の解明
Grant number：24K12261 2024.04 - 2027.03
独立行政法人日本学術振興会 科学研究費基金 基盤研究(C)
Authorship：Principal investigator