OKITA Yoshiko

写真a

Affiliation

Faculty of Medicine School of Medicine Department of Clinical Neuroscience, Neurosurgery

Title

Professor

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Papers 【 display / non-display

  • Cerebral Hemodynamics in Pediatric Abusive Head Trauma: 3 Severe Cases with Preserved Motor Cortex, Hyperperfusion, and Recovery of Mild Paralysis Reviewed

    TAMURA Mitsuru, YAMASHITA Shinji, KAWANO Tomoki, KOMAKI Satoru, TSUKINO Takeru, KOJIMA Koutarou, MAEDA Kenichi, KIMOTO Yasuhiro, KADOTA Yoshihito, AZUMA Minako, OKITA Yoshiko

    NMC Case Report Journal   13 ( 0 )   69 - 75   2026.12

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:The Japan Neurosurgical Society  

    DOI: 10.2176/jns-nmc.2025-0258

    PubMed

    CiNii Research

  • Molecular characteristics of isocitrate dehydrogenase 1 R132C-mutant diffuse gliomas: association with TP53 alterations and Li-Fraumeni syndrome. Reviewed International journal

    Shinji Yamashita, Fumitaka Matsumoto, Kiyotaka Saito, Masato Hidaka, Souma Arikawa, Tomoki Kawano, Tomohiro Kawano, Mitsuru Tamura, Hironobu Okuyama, Nayuta Higa, Ryosuke Hanaya, Toshiaki Akahane, Akihide Tanimoto, Yuichiro Sato, Yoshiko Okita

    Acta neuropathologica communications   2026.7

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1186/s40478-026-02369-w

    PubMed

  • Rural medical disparities in multimodal glioblastoma treatment. Reviewed International journal

    Yasutomo Momii, Nobuhiro Hata, Hirotaka Fudaba, Hajime Yonezawa, Naoki Shinojima, Tetsuya Negoto, Kenta Ujifuku, Hideki Nagamine, Daisuke Kuga, Yukiko Nakahara, Shinji Yamashita, Yoshiteru Nakano, Toshiyuki Enomoto, Ryosuke Hanaya, Akitake Mukasa, Motohiro Morioka, Takayuki Matsuo, Tadashi Hamasaki, Koji Yoshimoto, Tatsuya Abe, Yoshiko Okita, Junkoh Yamamoto, Hiroshi Abe, Minoru Fujiki

    Scientific reports   2026.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-026-48867-8

    PubMed

  • Comparing artificial intelligence and physician performance in predicting IDH mutation status in glioma. Reviewed

    Takahashi S, Takahashi M, Kinoshita M, Miyake M, Kawaguchi R, Shinojima N, Mukasa A, Saito K, Nagane M, Otani R, Higuchi F, Tanaka S, Hata N, Tamura K, Tateishi K, Nishikawa R, Arita H, Nonaka M, Uda T, Fukai J, Okita Y, Tsuyuguchi N, Kanemura Y, Tsushima F, Kakeda S, Akashi T, Taoka T, Watanabe Y, Yamada K, Hirai T, Azuma M, Yoshiura T, Sese J, Ichimura K, Narita Y, Hamamoto R

    NPJ digital medicine   2026.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41746-026-02695-2

    PubMed

  • Genetic and structural changes leading to symptomatic Currarino syndrome – case presentation with re-analyzation of 102 cases of MNX1 genetic change Reviewed

    Okuyama H., Yokogami K., Yamashita S., Okita Y.

    Human Pathology Reports   43   2026.3

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    Publishing type:Research paper (scientific journal)   Publisher:Human Pathology Reports  

    Currarino syndrome is a rare congenital disorder characterized by a triad of presacral mass, sacral agenesis, and anorectal malformation. We report a case of Currarino syndrome with heterozygous in-frame deletion in homeobox of MNX1 gene. Currarino syndrome is an autosomal-dominant inheritance, and many cases of MNX1 mutations have been reported, but there are no reports of symptomatic with heterozygous in-frame deletions in sporadic cases. We downloaded the MNX1 data from open database ClinVar-NCBI. After adding seven literature reports not included in the database with present case, we re-analyzed the mutation type, location and symptoms. Among 81 cases with gene mutations upstream of homeobox, structural changes in homeobox were observed in 39 of 41 symptomatic cases (95.1%), while in only 1 of 40 asymptomatic cases (2.5%). This finding indicates that structural changes in the homeobox of the MNX1 gene are significantly involved in whether Currarino syndrome becomes symptomatic.

    DOI: 10.1016/j.hpr.2025.300809

    Scopus

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Presentations 【 display / non-display

  • 悪性脳腫瘍の診断と集学的治療

    沖田 典子

    神戸オンコロジーセミナー  2025.12.11 

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    Event date: 2025.12.11

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • 悪性脳腫瘍診療と私なりのリーダーシップ ― 女性が管理職になるということ

    沖田 典子

    愛知脳神経外科カンファレンス2025  2025.8.7 

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    Event date: 2025.12.6

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • 悪性脳腫瘍の診断と集学的治療

    沖田 典子

    第14回Mt.Tsukuba  2025.11.7 

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    Event date: 2025.11.7

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • KINEVO 900Sが可能にする術者の体格に左右されない脳腫瘍手術

    沖田 典子

    日本脳神経外科第84回学術集会  2025.10.29 

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    Event date: 2025.10.29 - 2025.11.1

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

  • 少人数医局における脳腫瘍手術の安全管理ー合併症対策の実際と工夫

    沖田 典子

    日本脳神経外科第84回学術集会  2025.10.30 

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    Event date: 2025.10.29 - 2025.11.1

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

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Grant-in-Aid for Scientific Research 【 display / non-display

  • 膠芽腫に対する新規治療法の探索を可能とするデジタルツインの基盤技術開発

    Grant number:25K22913  2025.04 - 2027.03

    独立行政法人日本学術振興会  科学研究費基金  挑戦的研究(萌芽)

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    Authorship:Coinvestigator(s) 

  • 膠芽腫におけるシングルセルラマン分光法の確立による腫瘍細胞特性の解明

    Grant number:24K12261  2024.04 - 2027.03

    独立行政法人日本学術振興会  科学研究費基金  基盤研究(C)

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    Authorship:Principal investigator