沖田　典子 (オキタ　ヨシコ)

OKITA Yoshiko

写真a

所属

医学部 医学科 臨床神経科学講座脳神経外科学分野

職名

教授

関連SDGs


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  • Ophthalmic Artery Feeders in Meningioma Reduce the Effectiveness of Transarterial Embolization With n-Butyl Cyanoacrylate 査読あり

    Takenaka T., Nishida T., Takagaki M., Okita Y., Kijima N., Hirayama R., Matsui Y., Yamada S., Fukuda T., Nakagawa R., Matsumura T., Nakamura H., Kagawa N., Kishima H.

    World Neurosurgery   194   123463   2025年2月

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    記述言語：英語   掲載種別：研究論文（学術雑誌）   出版者・発行元：World Neurosurgery  

    Background: N-butyl cyanoacrylate (n-BCA) is often used for preoperative transarterial embolization (TAE) of meningiomas. However, factors affecting the embolization effect with n-BCA remain unclear. This study aimed to clarify the factors associated with the embolization rate after TAE using n-BCA in meningioma, from the aspect of feeder architecture. Methods: We retrospectively analyzed 62 patients with meningioma who underwent preoperative TAE with n-BCA between 2016 and 2021. Patient variables, including characteristics, intraoperative findings, and outcomes, were collected. Feeder architecture was classified into 7 groups: 1) internal maxillary artery, 2) occipital artery, 3) ascending pharyngeal artery, 4) posterior meningeal artery, 5) infraclinoidal internal carotid artery, 6) ophthalmic artery (OphA), and 7) pial feeder group, based on preoperative angiography. We set primary outcome as the embolization rate, representing the reduction rate of the gadolinium-enhanced lesion volume observed on contrast-enhanced magnetic resonance imaging. Angiographic findings following n-BCA injection were classified as feeder occlusion or intratumoral embolization. We analyzed the factors associated with the embolization rate. Results: The OphA feeder group showed a decrease in the embolization rate (P = 0.008). The number of feeder groups with intratumoral embolization showed a robust positive correlation (r = 0.557). The OphA feeder group showed an increase in the number of feeder groups (P < 0.001) and larger tumor volume (P = 0.005). Conclusions: The OphA feeder group was associated with a lower embolization rate. Our study suggested that the vascular architecture in meningioma affected the efficacy of TAE with n-BCA.

    DOI： 10.1016/j.wneu.2024.11.046

    Scopus

    PubMed

  • When machines start examining tissue specimens on their own. 査読あり

    Kinoshita M, Okita Y, Kishima H

    Neuro-oncology   2025年1月

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    記述言語：英語   掲載種別：研究論文（学術雑誌）  

    DOI： 10.1093/neuonc/noaf021

    PubMed

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科研費（文科省・学振・厚労省）獲得実績 【 表示 ／ 非表示 】

  • 膠芽腫におけるシングルセルラマン分光法の確立による腫瘍細胞特性の解明

    研究課題/領域番号：24K12261  2024年04月 - 2027年03月

    独立行政法人日本学術振興会  科学研究費基金  基盤研究(C)

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    担当区分：研究代表者 

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