|
Affiliation |
Engineering educational research section Applied Chemistry Program |
|
Title |
Assistant Professor |
|
External Link |
|
|
Related SDGs |
|
MIYATAKE Munetoshi
|
|
|
Degree 【 display / non-display 】
-
博士(工学) ( 2010.3 宮崎大学 )
-
工学修士 ( 1995.3 宮崎大学 )
-
工学士 ( 1993.3 宮崎大学 )
Research Areas 【 display / non-display 】
-
Nanotechnology/Materials / Bio chemistry
-
Nanotechnology/Materials / Green sustainable chemistry and environmental chemistry
-
Manufacturing Technology (Mechanical Engineering, Electrical and Electronic Engineering, Chemical Engineering) / Biofunction and bioprocess engineering
-
Environmental Science/Agriculture Science / Environmental load reduction and remediation
-
Life Science / Applied microbiology
Papers 【 display / non-display 】
-
Yamaguchi M., Yoshiyama T., Maruyama R., Ohashi M., Nishizono S., Kobayashi T., Miyatake M., Sameshima H.
Journal of Obstetrics and Gynaecology Research 50 ( 12 ) 2299 - 2308 2024.12
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Journal of Obstetrics and Gynaecology Research
Aim: To evaluate Hyuganatsu oranges (Citrus tamurana Hort. Ex Tanaka) derived arabinogalactan for bone turnover, we performed a randomized placebo-controlled trial. Methods: Sixty-three postmenopausal women were age-stratified and randomly assigned to receive arabinogalactan-rich hyuganatsu juice (study group) or a placebo drink (control group) for 90 days. We measured blood tartrate-resistant acid phosphatase 5b (TRACP5b), type I procollagen N-terminal propeptide (P1NP), and other bone turnover biomarker levels at baseline, days 45 and 90 (T90) of the intervention, and day 30 of recovery. Cumulative effects were compared between groups using repeated-measures linear mixed model analysis. The primary endpoint was the difference between the pre- and post-intervention TRACP5b and P1NP levels. Results: Using repeated measures linear mixed model analysis, the study group had significantly lower TRACP5b and P1NP levels at day 90 than the control group (mean [95% confidence interval]; TRACP5b: 310.0 [269.2–350.9] vs. 386.4 [341.2–431.6] mU/dL; P1NP: 53.7 [48.6–58.7] vs. 70.3 [64.1–76.4] ng/mL), whereas other biomarker levels showed no change. Conclusion: Arabinogalactan-rich Hyuganatsu juice suppressed bone mineral turnover and potentially improved ovarian hormone deficiency-induced osteoporosis in postmenopausal women.
DOI： 10.1111/jog.16116
-
Study on Arsenic Methyltransferase of Cellulomonas sp. K31 Expressed in Recombinant E. coli Reviewed
Munetoshi MIYATAKE, Hideki MATSUNE, Koichiro SHIOMORI
Resources Processing 69 ( 3 ) 127 - 132 2023.2
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
-
Study on Arsenic Methylation Properties of Cellulomonas sp. K31 Reviewed
Munetoshi MIYATAKE, Jun HIROSE, Koichiro SHIOMORI, Haruhiko YOKOI
Resources Processing 68 ( 3 ) 117 - 123 2022.2
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.4144/rpsj.68.117
-
M. Miyatake, S. Nishizono, T. Kobayashi, S. Sakatani, J. Matsubara, M. Yamaguchi
Food Science and Technology Research 27 ( 6 ) 907 - 914 2021.11
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) Publisher：公益社団法人 日本食品科学工学会
DOI： 10.3136/fstr.27.907
-
Hirose J., Tsukimata R., Miyatake M., Yokoi H.
Genes 11 ( 12 ) 1 - 13 2020.12
Language：English Publishing type：Research paper (scientific journal) Publisher：Genes
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Pseudomonas sp. strain LLC-1 (NBRC 111237) is capable of degrading lignin-derived low-molecular-weight compounds (LLCs). The genes responsible for the catabolism of LLCs were characterized in this study using whole-genome sequencing. Despite the close phylogenetic relationship with Pseudomonas putida, strain LLC-1 lacked the genes usually found in the P. putida genome, which included fer, encoding an enzyme for ferulic acid catabolism, and rvdh encoding an NAD+-dependent aldehyde dehydrogenase specific for its catabolic intermediate, vanillin. Cloning and expression of the 8.5 kb locus adjacent to the van operon involved in vanillic acid catabolism revealed the bzf gene cluster, which is involved in benzoylformic acid catabolism. One of the structural genes identified, bzfC, expresses the enzyme (BzfC) having the ability to transform vanillin and syringaldehyde to corresponding acids, indicating that BzfC is a multifunctional enzyme that initiates oxidization of LLCs in strain LLC-1. Benzoylformic acid is a catabolic intermediate of (R,S)-mandelic acid in P. putida. Strain LLC-1 did not possess the genes for mandelic acid racemization and oxidation, suggesting that the function of benzoylformic acid catabolic enzymes is different from that in P. putida. Genome-wide characterization identified the bzf gene responsible for benzoylformate and vanillin catabolism in strain LLC-1, exhibiting a unique mode of dissimilation for biomass-derived aromatic compounds by this strain.
Presentations 【 display / non-display 】
-
Cellulomonas sp. M27株によるヒ素のメチル化特性
宮武宗利、廣瀬 遵、松根英樹、塩盛弘一郎
環境バイオテクノロジー学会2024年度大会 2024.5.30
Event date： 2024.5.30 - 2024.5.31
Language：Japanese Presentation type：Poster presentation
-
環境浄化に寄与するPseudomonas属細菌由来の染色体組込み型接合因子のデータベースからの検索
藤波寛人、宮武宗利、廣瀬 遵
環境バイオテクノロジー学会2024年度大会 2024.5.30
Event date： 2024.5.30 - 2024.5.31
Language：Japanese Presentation type：Poster presentation
-
Pseudomonas sp. LLC-1株によるα-トルイル酸の分解特性
福吉晃大、稲吉秀次郎、榎本翔也、宮武宗利、廣瀬 遵
環境バイオテクノロジー学会2024年度大会 2024.5.30
Event date： 2024.5.30 - 2024.5.31
Language：Japanese Presentation type：Poster presentation
-
Study on Arabinogalactan Estimation for Hyuganatsu Orange (Citrus tamurana Hort. ex Tanaka) Using FT-IR/ATR
2023.9.7
Event date： 2023.9.4 - 2023.9.8
Language：Japanese Presentation type：Oral presentation (general)
-
Research on highly active porous capsules encapsulating enzymes
2023.7.1
Event date： 2023.7.1
Language：Japanese Presentation type：Poster presentation
Awards 【 display / non-display 】
-
日本果汁協会技術賞
2021.9 日本果汁協会 日向夏を用いた骨代謝改善飲料の開発
西園祥子、宮武宗利、小林太一、山口昌俊、坂谷洋一郎、松原順子、武曽歩
Award type：Honored in official journal of a scientific society, scientific journal
Grant-in-Aid for Scientific Research 【 display / non-display 】
-
微生物のヒ素メチル基転移酵素を担持した高メチル化活性クライオゲルの開発
Grant number：24K15339 2024.04 - 2027.03
独立行政法人日本学術振興会 科学研究費基金 基盤研究(C)
Authorship：Principal investigator
-
オリゴシルセスキオキサンを用いた次世代型遺伝子導入剤の開発
Grant number：22K04818 2022.04 - 2025.03
独立行政法人日本学術振興会 科学研究費補助金 基盤研究(C)
松根 英樹、
Authorship：Coinvestigator(s)
-
Bacillus属菌が生産するセルラーゼに関する研究
Grant number：9915033 1997.04 - 1998.03
科学研究費補助金 奨励研究(B)
Authorship：Principal investigator
土壌より分離したBacillus属菌が生産するセルラーゼについて、基質への作用様式を明らかにするため、結合ドメインを同定しセロオリゴ糖を基質に用いたときの分解生成物を検討した。さらに天然及び再生セルロースへ作用させ、構造との関連を調べた。
Available Technology 【 display / non-display 】
-
微生物機能を利用した環境浄化・修復に関する研究
微生物を利用した機能性物質の生産に関する研究
機能性多糖の構造に関する研究Message：・共同研究の希望テーマ：糖質の構造と機能に関する研究