KONOMOTO Takao

写真a

Affiliation

Faculty of Medicine School of Medicine Department of Developmental and Urological-Reproductive Medicine, Pediatrics

Title

Associate Professor

External Link

Degree 【 display / non-display

  • 博士(医学) ( 2016.3   宮崎大学 )

Research Areas 【 display / non-display

  • Life Science / Nephrology

  • Life Science / Embryonic medicine and pediatrics

 

Papers 【 display / non-display

  • Eculizumab for paediatric patients with atypical haemolytic-uremic syndrome: full dataset analysis of post-marketing surveillance in Japan.

    Ito S, Hataya H, Ashida A, Hamada R, Ishikawa T, Ishikawa Y, Shimono A, Konomoto T, Miyazawa T, Ogura M, Tanaka K, Kagami S

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association   2022.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1093/ndt/gfac150

    PubMed

  • Clinical and histological features in pediatric and adolescent/young adult patients with renal disease: a cross-sectional analysis of the Japan Renal Biopsy Registry (J-RBR) Reviewed

    Urushihara M., Sato H., Shimizu A., Sugiyama H., Yokoyama H., Hataya H., Matsuoka K., Okamoto T., Ogino D., Miura K., Hamada R., Hibino S., Shima Y., Yamamura T., Kitamoto K., Ishihara M., Konomoto T., Hattori M., Hasebe N., Nakagawa N., Shibazaki S., Miyamoto T., Ito M., Nishio S., Nakazawa D., Sato Y., Suzuki A., Moniwa N., Tanaka M., Fukasawa Y., Takizawa H., Soma J., Nakaya I., Kazama J.J., Tanaka K., Tanaka M., Sato T., Sanada S., Hashimoto H., Miyazaki M., Nagasawa T., Okamoto K., Konta T., Ichikawa K., Kitamura H., Imasawa T., Matsumura C., Akutsu N., Kamura K., Takeda T., Ishimitsu T., Hiromura K., Kaneko Y., Ikeuchi H., Sakairi T., Nagata D., Saito O., Akimoto T., Maeshima A., Yokoo T., Tsuboi N., Koike K., Tanno Y., Yokote S., Miyazaki Y., Ueda H., Okabe M., Tanaka M., Ikeda M., Shimizu A., Suzuki Y., Goda T., Kihara M., Takagi M., Ishikawa M., Kaname S., Karube M., Fukuoka K., Kawakami T., Ebihara I., Sato C., Sakai Y., Hirama A., Mii A., Fuke Y., Abe M., Okada H., Inoue T., Iwashita T., Kogure Y., Kanozawa K., Hasegawa H., Ubukata M., Shibata T., Inoue Y., Suzuki T., Ichikawa D., Shirai S., Shibagaki Y., Wada T.

    Clinical and Experimental Nephrology   25 ( 9 )   1018 - 1026   2021.9

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Clinical and Experimental Nephrology  

    Background: Only a few studies have investigated epidemiological and clinicopathological information regarding pediatric and adolescent and young adult (AYA) patients with renal disease. The purpose of this study was to clarify the differences and relationship of clinicopathological findings between pediatric and AYA patients using the Japan Renal Biopsy Registry (J-RBR). Methods: This cross-sectional study analyzed data from patients registered in the J-RBR between 2007 and 2017. Clinicopathological findings at diagnosis were analyzed for 3,463 pediatric (age < 15 years) and 6,532 AYA (age 15–30 years) patients. Results: Although chronic nephritic syndrome was the most common clinical diagnosis at age > 5 years, nephrotic syndrome was the most frequent diagnosis at age < 4 years. The most common pathological diagnosis as classified by pathogenesis in pediatric patients was primary glomerular disease (except IgA nephropathy), whereas IgA nephropathy was increased in AYA patients. Mesangial proliferative glomerulonephritis was the most common pathological diagnosis as classified by histopathology in both pediatric and AYA patients. Minor glomerular abnormalities were the most frequent histopathologic diagnoses of nephrotic syndrome in childhood, but their frequency decreased with age. Conclusion: To the best of our knowledge, this is the first report of clinicopathological features of pediatric and AYA patients in a large nationwide registry of renal biopsy. There were differences of clinical, pathological and histopathologic findings between pediatric and AYA patients.

    DOI: 10.1007/s10157-021-02077-w

    Scopus

    PubMed

  • 急速に片側腎の機能低下を認めたシスチン尿症の1例 Reviewed

    黒木純、此元 隆雄, 今村 秀明, 中原 梢, 寺田 直樹, 上村 敏雄, 賀本 敏行, 盛武 浩

    日本小児腎不全学会雑誌   40   297 - 300   2020.7

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

  • 神経因性膀胱を契機に診断された尾部退行症候群の乳児例 Reviewed

    堂福美佳、今村 秀明, 上別府 豊治, 上村 敏雄, 賀本 敏行, 此元 隆雄, 盛武 浩

    日本小児腎不全学会雑誌   40   139 - 142   2020.7

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    Publishing type:Research paper (scientific journal)  

  • 来たる大震災に備えて-震災時の実情と対策- 小児腎疾患と災害対策 Invited Reviewed

    此元隆雄

    日本小児腎不全学会雑誌   40   66 - 72   2020.7

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    Authorship:Lead author   Language:Japanese   Publishing type:Research paper (scientific journal)  

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Books 【 display / non-display

  • 【小児疾患診療のための病態生理2 改訂第6版】腎・泌尿器疾患 蛋白尿

    黒木純、此元隆雄( Role: Joint editor)

    東京医学社  2022.1 

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    Language:Japanese Book type:Scholarly book

MISC 【 display / non-display

  • 【小児疾患診療のための病態生理2 改訂第6版】腎・泌尿器疾患 蛋白尿

    黒木 純、此元隆雄

    小児内科   53 ( 増刊 )   2022.1

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    Authorship:Corresponding author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  • 【尿細管間質障害-最新の知見】電解質異常・代謝性疾患に伴う尿細管間質障害 アミノ酸代謝異常 Invited

    此元隆雄

    腎と透析   87 ( 2 )   303 - 307   2019.8

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  • Essential points from Evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018

    Okada H., Yasuda Y., Kashihara N., Asahi K., Ito T., Kaname S., Kanda E., Kanno Y., Shikata K., Shibagaki Y., Tsuchiya K., Tsuruya K., Nagata D., Narita I., Nangaku M., Hattori M., Hamano T., Fujimoto S., Moriyama T., Yamagata K., Yamamoto R., Wakasugi M., Ashida A., Usui J., Kawamura K., Kitamura K., Konta T., Suzuki Y., Tsuruoka S., Nishio S., Hamano T., Fujii N., Fujii H., Wada T., Yokoyama H., Aoki K., Akiyama D., Araki S., Arima H., Ishikawa E., Ishikura K., Ishizuka K., Ishimoto T., Ishimoto Y., Iseki K., Itabashi M., Ichioka S., Ichikawa K., Ichikawa D., Inoue S., Imai T., Imamura H., Iwata Y., Iwazu Y., Usui T., Uchida K., Egawa M., Ohara S., Omori N., Okada R., Okuda Y., Ozeki T., Obata Y., Kai H., Kato N., Kanasaki K., Kaneko Y., Kabasawa H., Kawaguchi T., Kawasaki Y., Kawashima K., Kawano H., Kikuchi K., Kihara M., Kimura Y., Kurita N., Koike K., Koizumi M., Kojima C., Goto S., Konomoto T., Kohagura K., Komatsu H., Komaba H., Saito C., Sakai Y., Sakaguchi Y., Satonaka H., Jimi K., Shimizu A., Shimizu S., Shirai S., Shinzawa M., Sugiyama K., Suzuki T., Suzuki H., Suyama K., Segawa H., Takahashi K., Tanaka K.

    Clinical and Experimental Nephrology   23 ( 1 )   2019.1

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Publisher:Clinical and Experimental Nephrology  

    DOI: 10.1007/s10157-018-1648-1

    Scopus

  • 浮腫・ネフローゼ状態への輸液(Q&A/特集)

    此元隆雄

    わかる輸液-体液の生理を知り、正しい輸液オーダーができる!-   4 ( 3 )   683 - 689   2014.7

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:総合医学社  

Presentations 【 display / non-display

  • 遺伝学的検査で不確実な結果が出たジュベール症候群に対する遺伝カウンセリングの経験

    丸山 るり子, 伊井 美奈代, 槇野 晋也, 土井 宏太郎, 此元 隆雄, 山口 昌俊

    第46回日本遺伝カウンセリング学会  2022.7 

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    Event date: 2022.7.1 - 2022.7.3

    Language:Japanese   Presentation type:Oral presentation (general)  

  • リツキシマブ投与後にB細胞クラススイッチ異常による遷延性低ガンマグロブリン血症きたしたネフローゼ症候群の一例

    此元 隆雄, 黒木 純, 田中 悦子, 阪口 嘉美, 盛武 浩

    第57回日本小児腎臓病学会  2022.5 

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    Event date: 2022.5.27 - 2022.5.28

    Language:Japanese   Presentation type:Oral presentation (general)  

  • ダサチニブによる薬剤性ネフローゼ症候群を発症した一例

    木下 弘一, 黒木 純, 永澤 俊, 中川 緑, 阪口 嘉美, 山田 愛, 田中 悦子, 木下 真理子, 上村 幸代, 齋藤 祐介, 此元 隆雄, 盛武 浩

    第125回日本小児科学会学術集会  2022.4 

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    Event date: 2022.4.15 - 2022.4.17

    Language:Japanese   Presentation type:Oral presentation (general)  

  • ダサチニブによる薬剤性ネフローゼ症候群を発症した一例

    木下弘一、黒木 純、永澤 俊、中川緑、阪口嘉美、山田 愛、田中悦子、木下真理子、上村幸代、齋藤祐介、此元隆雄、盛武 浩

    第34回九州小児ネフロロジー研究会  2021.9.18 

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    Event date: 2021.9.18

    Language:Japanese   Presentation type:Oral presentation (general)  

  • アセトアミノフェンによる薬剤性間質性腎炎と診断した1例

    海老原 秀生, 黒木 純, 阪口 嘉美, 田中 悦子, 此元 隆雄

    第90回日本小児科学会宮崎地方会  2021.9.12 

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    Event date: 2021.9.12

    Presentation type:Oral presentation (general)  

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Grant-in-Aid for Scientific Research 【 display / non-display

  • 尿中ボウマン嚢上皮細胞mRNAによる糸球体腎炎の非侵襲的バイオマーカーの確立

    2017.05 - 2019.03

    科学研究費補助金  基盤研究(C)

  • インターロイキン17Eの糸球体上皮細胞シグナル伝達障害による蛋白尿発症機序の解明

    2009.04 - 2011.03

    科学研究費補助金  若手研究(B)

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    Authorship:Principal investigator 

    ヒト培養ポドサイトを用いてインターロイキン17Eの糸球体上皮細胞シグナル伝達障害による蛋白尿発症機序の解明する。