KOMATSU Hiroyuki

写真a

Affiliation

Faculty of Medicine Center for the Support and Development of Medical Professionals Department of Clinical Education

Title

Professor

External Link

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Degree 【 display / non-display

  • Doctor of Philosophy in Medicine ( 2005.3   University of Miyazaki )

Research Interests 【 display / non-display

  • 医学

  • Education, human, and sociology

Research Areas 【 display / non-display

  • Life Science / Nephrology

  • Life Science / Medical management and medical sociology  / 医学教育学

Education 【 display / non-display

  • University of Miyazaki   Graduate School, Division of Medicine   the speciality of Bioregulation

    - 2005.3

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    Country:Japan

  • Miyazaki Medical College   Faculty of Medicine

    - 1998.3

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    Country:Japan

Campus Career 【 display / non-display

  • University of Miyazaki   Faculty of Medicine   Center for the Support and Development of Medical Professionals   Professor

    2021.04 - Now

  • University of Miyazaki   Faculty of Medicine   Center for the Support and Development of Medical Professionals   Professor

    2016.03 - 2021.03

  • University of Miyazaki   Faculty of Medicine   Medicine educational reform promotion center   Associate Professor

    2008.11 - 2016.02

  • University of Miyazaki   Faculty of Medicine   College Hospital   Clinical training center after [sotsu]   Assistant Professor

    2007.04 - 2008.10

  • University of Miyazaki   Faculty of Medicine   College Hospital   Clinical training center after [sotsu]   Research Assistant

    2006.01 - 2007.03

External Career 【 display / non-display

  • 天理よろづ相談所病院   総合診療部ジュニアレジデント

    1998.5 - 2000.3

Professional Memberships 【 display / non-display

  • Japanese Society of Internal Medicine

    1998.6

  • Japanese Society of Nephrology

    2001.5

  • Japanese Society of Dialysis Therapy

    2001.4

  • Japanese Society for Medical Education

    1999.7

  • The Japan Primary Care Association

    2010.4

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Papers 【 display / non-display

  • Effect of tonsillectomy combined with steroid pulse therapy upon IgA nephropathy depending on proteinuria status at diagnosis: a nationwide multicenter cohort study in Japan Reviewed

    Komatsu H., Fujimoto S., Sato Y., Yasuda T., Yasuda Y., Matsuzaki K., Hirano K., Kawamura T., Yokoo T., Suzuki Y., Maruyama S.

    Clinical and Experimental Nephrology   28 ( 12 )   1272 - 1281   2024.12

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Clinical and Experimental Nephrology  

    Background: The effects of tonsillectomy combined with steroid pulse (TSP) therapy for IgA nephropathy (IgAN) are little known. Therefore, we examined the effects of TSP therapy on the kidney outcomes of IgAN in a large, nationwide cohort study in Japan. Methods: Between 2002 and 2004, 632 IgAN patients with ≥ 0.5 g/day proteinuria at diagnosis were divided into three groups with mild (0.50–0.99 g/day; n = 264), moderate (1.00–1.99 g/day, n = 216), or severe (≥ 2.00 g/day; n = 153). Decline in kidney function and urinary remission were compared among the three groups after TSP therapy, corticosteroid (ST) therapy, or conservative therapy during a mean follow-up of 6.2 ± 3.3 years. 10.6% and 5.9% of patients in the ST and conservative therapy group underwent tonsillectomy. Results: The rate of urinary remission at the final observation was significantly higher in the TSP therapy group than in the ST or conservative therapy groups (mild proteinuria: 64%, 43%, and 41%; moderate proteinuria: 51%, 45%, and 28%; severe proteinuria: 48%, 30%, and 22%, respectively). In contrast, the rate of a 50% increase in serum creatinine was lower in groups TSP therapy, than ST or conservative therapy (mild proteinuria: 2.1%, 10.1% and 16.7%; moderate proteinuria: 4.8%, 8.8% and 27.7%; severe proteinuria: 12.0%, 28.9% and 43.1%, respectively). In multivariate analysis, TSP therapy significantly prevented a 50% increase in serum creatinine levels compared with conservative therapy in groups with moderate and severe proteinuria (hazard ratio, 0.12 and 0.22, respectively). Conclusion: TSP significantly increased the rate of proteinuria disappearance and urinary remission in IgAN patients with mild-to-moderate urinary protein levels. It may also reduce the decline in kidney function in patients with moderate-to-severe urinary protein levels.

    DOI: 10.1007/s10157-024-02530-6

    Scopus

    PubMed

  • Development of medical knowledge content for problem-solving competencies through dialogue with the undergraduate medical education community in Japan Reviewed

    Nomura O., Komatsu H., Matsuyama Y., Onoue T., Ikusaka M., Okazaki H., Konishi Y.

    Medical Teacher   46 ( sup1 )   S61 - S66   2024

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Medical Teacher  

    Background: Discrepancies existed between the medical knowledge sections of the Model Core Curriculum for Medical Education (MCC) and the Guidelines for the National Examination for Medical Practitioners (GNEMP) in Japan. These discrepancies have been one of the underlying factors hindering the development of learner-centered medical education in the country. The project team responsible for the ‘Problem-Solving’ section of the MCC aimed to address discrepancies between the disease lists in the MCC and the GNEMP. Method: We refined the disease list for the 2022 revision of the MCC using a three-phase process: (a) procedure development, (b) selection, and (c) adjudication. First, we developed a scoring system for sifting and prioritizing diseases in the GNEMP, selecting those that met our scoring criteria. An expert adjudication panel then finalized the list of diseases through discussion. Results: Among the 1,456 diseases identified in the GNEMP, 781 met the selection criteria. The adjudication panel selected 56 of these diseases to be newly added to the 2022 MCC, resulting in a total of 691 diseases. Conclusions: The list of diseases defined as required medical knowledge in the MCC was finalized through dialogue among medical education stakeholders, effectively minimizing discrepancies between the MCC and GNEMP.

    DOI: 10.1080/0142159X.2024.2385707

    Scopus

    PubMed

  • Current treatment status of IgA nephropathy in Japan: a questionnaire survey Reviewed

    Matsuzaki K., Suzuki H., Kikuchi M., Koike K., Komatsu H., Takahashi K., Narita I., Okada H.

    Clinical and Experimental Nephrology   27 ( 12 )   1032 - 1041   2023.12

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Clinical and Experimental Nephrology  

    Background: In 2020, the Committee of Clinical Practical Guideline for IgA Nephropathy (IgAN) revised the clinical practice guidelines. Herein, we conducted a questionnaire survey to assess the potential discrepancies between clinical practice guidelines and real-world practice in Japan. Methods: A web-based survey of members of the Japanese Society of Nephrology was conducted between November 15 and December 28, 2021. Results: A total of 217 members (internal physicians: 203, pediatricians: 14) responded to the questionnaire. Of these respondents, 94.0% answered that the clinical practice guidelines were referred to “always” or “often.” Approximately 66.4% respondents answered that histological grade (H-Grade) derived from the “Clinical Guidelines for IgA nephropathy in Japan, 3rd version” and the “Oxford classification” were used for pathological classification. Moreover, 73.7% respondents answered that the risk grade (R-grade) derived from the “Clinical Guidelines for IgA nephropathy in Japan, 3rd version” was referred to for risk stratification. The prescription rate of renin–angiotensin system blockers increased based on urinary protein levels (> 1.0 g/day: 88.6%, 0.5–1.0 g/day: 71.0%, < 0.5 g/day: 25.0%). Similarly, the prescription rate of corticosteroids increased according to proteinuria levels (> 1.0 g/day: 77.8%, 0.5–1.0 g/day: 52.8%, < 0.5 g/day: 11.9%). The respondents emphasized on hematuria when using corticosteroids. In cases of hematuria, the indication rate for corticosteroids was higher than in those without hematuria, even if the urinary protein level was 1 g/gCr or less. Few severe infectious diseases or serious deterioration in glycemic control were reported during corticosteroid use. Conclusion: Our questionnaire survey revealed real-world aspects of IgAN treatment in Japan.

    DOI: 10.1007/s10157-023-02396-0

    Scopus

    PubMed

  • Kidney outcomes associated with haematuria and proteinuria trajectories among patients with IgA nephropathy in real-world clinical practice: The Japan Chronic Kidney Disease Database Reviewed

    Yano Y., Nagasu H., Kanegae H., Nangaku M., Hirakawa Y., Sugawara Y., Nakagawa N., Wada J., Sugiyama H., Nakano T., Wada T., Shimizu M., Suzuki H., Komatsu H., Nakashima N., Kitaoka K., Narita I., Okada H., Suzuki Y., Kashihara N.

    Nephrology   2023.10

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:Nephrology  

    Aim: Among patients with Immunoglobulin A (IgA) nephropathy, we aimed to identify trajectory patterns stratified by the magnitude of haematuria and proteinuria using repeated urine dipstick tests, and assess whether the trajectories were associated with kidney events. Methods: Using a nationwide multicentre chronic kidney disease (CKD) registry, we analysed data from 889 patients with IgA nephropathy (mean age 49.3 years). The primary outcome was a sustained reduction in eGFR of 50% or more from the index date and thereafter. During follow-up (median 49.0 months), we identified four trajectories (low-stable, moderate-decreasing, moderate-stable, and high-stable) in both urine dipstick haematuria and proteinuria measurements, respectively. Results: In haematuria trajectory analyses, compared to the low-stable group, the adjusted hazard ratios (HRs) (95% confidence interval [CI]) for kidney events were 2.59 (95% CI, 1.48–4.51) for the high-stable, 2.31 (95% CI, 1.19–4.50) for the moderate-stable, and 1.43 (95% CI, (0.72–2.82) for the moderate-decreasing groups, respectively. When each proteinuria trajectory group was subcategorized according to haematuria trajectories, the proteinuria group with high-stable and with modest-stable haematuria trajectories had approximately 2-times higher risk for eGFR reduction ≥50% compared to that with low-stable haematuria trajectory. Conclusion: Assessments of both haematuria and proteinuria trajectories using urine dipstick could identify high-risk IgA nephropathy patients.

    DOI: 10.1111/nep.14250

    Scopus

    PubMed

  • 4. Alignment of the 2022 Revision of the Model Core Curriculum for Medical Education in Japan with the‘Standards of the National Medical Practitioners Qualifying Examination' Reviewed

    Komatsu Hiroyuki, Yamawaki Masanaga, Ikusaka Masatomi, Eto Masato, Konishi Yasuhiko, Suzuki Keiichiro, Shimada Shoichi, Nomura Osamu, Matsuyama Yasushi, Gomi Harumi, Yamamoto Akira, Onoue Takeshi, Hasegawa Hitoshi, Takami Hideki, Okazaki Hitoaki

    Igaku Kyoiku / Medical Education (Japan)   54 ( 2 )   157 - 163   2023.4

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    Authorship:Lead author, Corresponding author   Language:Japanese   Publishing type:Research paper (scientific journal)   Publisher:Japan Society for Medical Education  

     In this revision, we have attempted to align the Model Core Curriculum for Medical Education competency, "problem-solving ability based on specialized knowledge," with the "Standards of National Examination for Medical Practitioners." The major diseases and syndromes in "Essential Fundamentals" correspond to the basic diseases in Table 1 of the Core Curriculum, symptoms, physical and laboratory examinations, and treatment in "General Medicine" correspond to the items in Table 2 of the Core Curriculum, and the diseases in "Medical Theory" correspond to the diseases in PS-02 of the Core Curriculum. The validity of the diseases in the Core Curriculum was verified using the evaluation results of the examination level classification of the "Research for Revision of National Examination Criteria." Approximately 690 diseases were conclusively selected. This revision mentions the number of diseases in the Core Curriculum for the first time. Hopefully, this will lead to a deeper examination of diseases that should be studied in medical schools in the future.

    DOI: 10.11307/mededjapan.54.2_157

    CiNii Research

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Books 【 display / non-display

  • エビデンスに基づくIgA腎症診療ガイドライン2020

    成田一衛、藤元昭一、鈴木祐介、小松弘幸、他( Role: Contributor)

    東京医学社  2020.8 

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    Total pages:78   Responsible for pages:43-45,55-58   Language:Japanese Book type:Scholarly book

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  • IgA腎症の病態と治療

    富野康日己、川村哲也、鈴木祐介、他( Role: Joint editor)

    中外医学社  2019.11 

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    Language:Japanese Book type:Scholarly book

  • 日常診療の中で学ぶプロフェッショナリズム

    宮田靖志、小泉俊三、他( Role: Joint editor)

    カイ書林  2018.7 

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    Language:Japanese Book type:Scholarly book

  • エビデンスに基づくCKD腎症診療ガイドライン2018

    岡田浩一、安田宣成、他(CKD診療ガイド・ガイドライン改定委員会)( Role: Joint editor)

    東京医学社  2018.6 

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    Language:Japanese Book type:Scholarly book

  • エビデンスに基づくIgA腎症診療ガイドライン2017

    藤元昭一、鈴木祐介、佐々木環、湯澤由紀夫、片渕律子、後藤眞、小松弘幸、鈴木仁、板野精之、高橋和男、酒巻裕一、渡辺博文、福田顕弘( Role: Joint editor)

    東京医学社  2017.6 

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    Total pages:130   Responsible for pages:64-68, 79-81, 121-127   Language:Japanese Book type:Scholarly book

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MISC 【 display / non-display

  • 第1回宮崎県病院内メディカルラリー開催

    小松弘幸

    日州医事   ( 825 )   19 - 21   2018.5

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)   Publisher:宮崎県医師会  

  • 平成29年度「All Miyazaki研修医スタートアップセミナー&ウェルカムパーティ」開催報告

    小松弘幸

    日州医事   ( 814 )   24 - 26   2017.6

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)   Publisher:宮崎県医師会  

  • 平成28年度「宮崎県内視鏡外科アニマルラボセミナーin佐土原」開催報告

    小松弘幸

    日州医事   ( 807 )   30 - 33   2016.11

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)   Publisher:宮崎県医師会  

  • IgA腎症の現状と宮崎大学の取り組み Invited

    小松弘幸

    宮崎県医師会医学会誌   40 ( 2 )   95 - 102   2016.9

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • 医師養成制度変革の現状と宮崎大学医療人育成支援センターの使命・挑戦 Invited

    小松弘幸

    宮崎県医師会医学会誌   40 ( 2 )   87 - 94   2016.9

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

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Presentations 【 display / non-display

  • Impact of tonsillectomy on renal survival in patients with IgA nephropathy. International conference

    Komatsu H, Fujimoto S, Hara S, Sato Y, Yamada K, Eto T

    ASN Renal Week 2003, 36th Annual Meeting  (San Diego, CA, USA)  American Society of Nephrology

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    Event date: 2003.11.12 - 2003.11.17

    Language:English   Presentation type:Poster presentation  

    Venue:San Diego, CA, USA  

  • Serum IgA/C3 ratio in patients with IgA nephropathy:The marker of the histological severity and treatment efficacy. International conference

    Komatsu H, Fujimoto S, Hara S, Sato Y, Yamada K, Eto T

    ASN Renal Week 2003, 36th Annual Meeting  (San Diego, CA, USA)  American Society of Nephrology

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    Event date: 2003.11.12 - 2003.11.17

    Language:English   Presentation type:Poster presentation  

    Venue:San Diego, CA, USA  

  • Significance of ‘Point of No Return’ in progressive IgA nephropathy. International conference

    Komatsu H, Fujimoto S, Hara S, Sato Y, Yamada K, Eto T

    ASN Renal Week 2004, 37th Annual Meeting  (St. Louis, Missouri, USA)  American Society of Nephrology

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    Event date: 2004.10.27 - 2004.11.1

    Language:English   Presentation type:Poster presentation  

    Venue:St. Louis, Missouri, USA  

  • A prospective cohort study on the effect of tonsillectomy combined with steroid pulse on IgA nephropathy. International conference

    Komatsu H, Fujimoto S, Hara S, Sato Y, Yamada K, Eto T

    ASN Renal Week 2005, 38th Annual Meeting  (Philadelphia, Pennsylvania, USA)  American Society of Nephrology

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    Event date: 2005.11.8 - 2005.11.13

    Language:English   Presentation type:Poster presentation  

    Venue:Philadelphia, Pennsylvania, USA  

  • A repeat biopsy study on the effect of tonsillectomy combined with steroid pulse therapy on IgA nephropathy. International conference

    Komatsu H, Fujimoto S, Hara S, Sato Y, Yamada K, Eto T

    ASN Renal Week 2006, 39th Annual Meeting  (San Diego, California, USA)  American Society of Nephrology

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    Event date: 2006.11.14 - 2006.11.19

    Language:English   Presentation type:Oral presentation (general)  

    Venue:San Diego, California, USA  

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Grant-in-Aid for Scientific Research 【 display / non-display

  • 共用試験の公的化を受けたシームレスな医師養成の実現に資する、共用試験と他の制度の評価・検討のための研究

    Grant number:25CA2015  2025.04 - 2026.03

    厚生労働省  厚生労働行政推進調査事業費補助金  医療政策・医師養成

    小西靖彦、小松弘幸

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    Authorship:Coinvestigator(s) 

  • AIによる対話技術を活用した模擬患者アバターでの仮想空間医療面接教育基盤の創生

    Grant number:24H00170  2024.04 - 2029.03

    独立行政法人日本学術振興会  科学研究費補助金  基盤研究(A)

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    Authorship:Coinvestigator(s) 

  • ICTを利用した医師国家試験の評価方法の開発と検証のための研究

    Grant number:24AC1001  2024.04 - 2027.03

    厚生労働省  厚生労働科学研究費補助金(政策科学総合研究事業)  医療政策・医師養成

    河北博文、淺田 義和、岡崎 仁昭、久保 沙織、小西 靖彦、小松弘幸、高村 昭輝、内藤 俊夫、奈良 信雄、錦織 宏、伴 信太郎、松山 泰、森 博威

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    Authorship:Coinvestigator(s) 

 

Committee Memberships 【 display / non-display

  • 文部科学省   「高度医療人材養成事業推進委員会」専門委員  

    2025.1 - 2025.3   

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    Committee type:政府

  • 文部科学省   質の高い臨床教育・研究の確保事業推進委員会  

    2023.5 - 2024.4   

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    Committee type:政府

  • 厚生労働省   医道審議会専門委員  

    2022.8   

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    Committee type:政府

  • 医学系大学間共用試験実施評価機構   医学系OSCE 実施管理委員会  

    2022.5   

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    Committee type:学協会

  • 医療系大学間共用試験実施評価機構   医学系OSCE 学修・評価項目改訂委員会  

    2022.5   

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    Committee type:学協会

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Social Activities 【 display / non-display

  • 宮崎から医師をめざそう!応援フォーラム

    Role(s): Appearance, Commentator, Presenter, Lecturer, Planner, Organizing member

    宮崎県臨床研修・専門研修運営協議会、宮崎大学医学部医療人育成推進センター  2025.10.12

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    Audience: Junior students, High school students, Teachers, Guardians, Governmental agency

    Type:Lecture

    宮崎県内の高校生に医師を目指してもらうために、宮崎県の医療の現状や医学部での教育内容、医師のキャリア、医学部合格への学習方法等を講演やパネルディスカッション方式で企画した。

  • 宮崎から医師をめざそう!応援フォーラム

    Role(s): Appearance, Commentator, Presenter, Lecturer, Planner, Organizing member

    宮崎県臨床研修・専門研修運営協議会、宮崎大学医学部医療人育成推進センター  2024.10.6

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    Audience: Junior students, High school students, Teachers, Guardians, Governmental agency

    Type:Lecture

    宮崎県内の高校生に医師を目指してもらうために、宮崎県の医療の現状や医学部での教育内容、医師のキャリア、医学部合格への学習方法等を講演やパネルディスカッション方式で企画した。

  • All Miyazaki研修医スタートアップセミナー&祝賀会

    Role(s): Appearance, Commentator, Presenter, Informant, Planner, Organizing member

    宮崎県臨床研修・専門研修運営協議会、宮崎大学医学部附属病院卒後臨床研修センター  2024.4.27

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    Audience: Governmental agency

    Type:Lecture

    宮崎県内の新研修医を対象に、イベント通じて基幹型臨床研修病院間の親睦を深め、特別講演会等で宮崎での研修意欲を高めてもらうために企画・開催している。

  • 宮崎から医師をめざそう!応援フォーラム

    Role(s): Appearance, Commentator, Presenter, Lecturer, Planner, Organizing member

    宮崎県臨床研修・専門研修運営協議会、宮崎大学医学部医療人育成推進センター  2023.10.15

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    Audience: Junior students, High school students, Teachers, Guardians, Governmental agency

    Type:Lecture

    宮崎県内の高校生に医師を目指してもらうために、宮崎県の医療の現状や医学部での教育内容、医師のキャリア、医学部合格への学習方法等を講演やパネルディスカッション方式で企画した。

  • All Miyazaki研修医スタートアップセミナー&祝賀会

    Role(s): Appearance, Commentator, Presenter, Informant, Planner, Organizing member

    宮崎県臨床研修・専門研修運営協議会、宮崎大学医学部附属病院卒後臨床研修センター  2023.4.8

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    Audience: Governmental agency

    Type:Lecture

    宮崎県内の新研修医を対象に、イベント通じて基幹型臨床研修病院間の親睦を深め、特別講演会等で宮崎での研修意欲を高めてもらうために企画・開催している。

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Media Coverage 【 display / non-display

  • 医療ルネサンス

    読売新聞  2025.11.11

  • 宮崎から医師をめざそう!応援フォーラム Newspaper, magazine

    宮崎日日新聞  2025.10.13

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    Author:Other 

  • 地域枠医師養成のキーパーソン

    宮崎県地域医療支援機構  KATERU 第18号  2025.3.1

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    Author:Other 

  • 宮崎から医師をめざそう!応援フォーラム Newspaper, magazine

    宮崎日日新聞  2024.10.7

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    Author:Other 

  • 宮崎から医師をめざそう!応援フォーラム Newspaper, magazine

    宮崎日日新聞  2023.10.16

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    Author:Other 

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