|
Affiliation |
Faculty of Medicine School of Nursing Integrated clinical nursing course |
|
Title |
Professor |
|
External Link |
|
|
Related SDGs |
|
YANAGITA Toshihiko
|
|
|
Degree 【 display / non-display 】
-
Doctor (Medicine) ( 1997.3 Miyazaki Medical College )
-
) ( 1990.3 Miyazaki Medical College )
Papers 【 display / non-display 】
-
巻頭言 Reviewed
柳田 俊彦
エキスパートナース 41 ( 6 ) 3 - 3 2025.4
Publishing type：Research paper (scientific journal) Publisher：(株)照林社
-
Maruta T., Kouroki S., Kurogi M., Hidaka K., Koshida T., Miura A., Nakagawa H., Yanagita T., Takeya R., Tsuneyoshi I.
Journal of Neuroscience Research 102 ( 10 ) e25386 2024.10
Language：English Publishing type：Research paper (scientific journal) Publisher：Journal of Neuroscience Research
Voltage-gated sodium channels, including NaV1.7, NaV1.8, and NaV1.9, play important roles in pain transmission and chronic pain development. However, the specific mechanisms of their action remain unclear, highlighting the need for in vivo stimulation studies of these channels. Optogenetics, a novel technique for targeting the activation or inhibition of specific neural circuits using light, offers a promising solution. In our previous study, we used optogenetics to selectively excite NaV1.7-expressing neurons in the dorsal root ganglion of mice to induce nocifensive behavior. Here, we further characterize the impact of nocifensive behavior by activation of NaV1.7, NaV1.8, or NaV1.9-expressing neurons. Using CRISPR/Cas9-mediated homologous recombination, NaV1.7–iCre, NaV1.8–iCre, or NaV1.9–iCre mice expressing iCre recombinase under the control of the endogenous NaV1.7, NaV1.8, or NaV1.9 gene promoter were produced. These mice were then bred with channelrhodopsin-2 (ChR2) Cre–reporter Ai32 mice to obtain NaV1.7–ChR2, NaV1.8–ChR2, or NaV1.9–ChR2 mice. Blue light exposure triggered paw withdrawal in all mice, with the strongest response in NaV1.8–ChR2 mice. These light sensitivity differences observed across NaV1.x–ChR2 mice may be dependent on ChR2 expression or reflect the inherent disparities in their pain transmission roles. In conclusion, we have generated noninvasive pain models, with optically activated peripheral nociceptors. We believe that studies using optogenetics will further elucidate the role of sodium channel subtypes in pain transmission.
DOI： 10.1002/jnr.25386
-
Assessment of insulin balls: A scoping review
Nakamura Sayuri, Kageura Naoko, Oe Makoto, Matsui Yuko, Horiguchi Tomomi, Ueda Terumi, Seto Natsuko, Yanagita Toshihiko, Sugama Junko
Journal of International Nursing Research 3 ( 1 ) e2023-0010 - e2023-0010 2024.2
Language：English Publishing type：Research paper (scientific journal) Publisher：一般社団法人 日本看護研究学会
Insulin balls are subcutaneous induration caused by amyloid deposition due to repeated insulin injections to the same site, and subcutaneous injections in this area cause poor glycemic control. Therefore, it is important to assess the site for insulin balls and change the injection site at an early stage, but the assessment method remains unclear. Therefore, we aimed to clarify the available methods for insulin ball assessment. Using the scoping review method, we searched Japanese and English literature from January 1964 to November 2022 using the keywords "insulin ball" and "assessment" and included those that met the selection criteria. Database searches were conducted in Japan Abstracts Society, PubMed, Scopus, and CINAHL. The number of adopted studies regarding insulin ball assessment was 11. Palpation and visual examination were the assessment methods used in all studies. Blood tests and ultrasonography were both performed in nine articles, magnetic resonance imaging (MRI) was performed in five articles, and computed tomography (CT) was performed in four articles. There were two types of insulin balls: palpable and nonpalpable. A paper reporting that nonpalpable insulin balls can be detected by ultrasonography was noted. In addition to palpation and visual examination, imaging tests such as ultrasonography, MRI, and CT are necessary because some insulin balls cannot be palpated. This study suggested that incorporating ultrasonography in addition to palpation and visual examination may be useful as a screening tool for the early detection of insulin balls. We now need to validate the accuracy of the assessment by ultrasonography.
-
Yanagita Toshihiko, Sasaguri Toshiyuki
Folia Pharmacologica Japonica 158 ( 2 ) 111 - 111 2023
Authorship：Lead author, Corresponding author Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japanese Pharmacological Society
DOI： 10.1254/fpj.23002
-
Yanagita Toshihiko
Folia Pharmacologica Japonica 158 ( 2 ) 119 - 127 2023
Authorship：Lead author, Corresponding author Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japanese Pharmacological Society
Active learning in pharmacology education “pharmacology role-play,” in which students pretend to be health professionals and patients and explain diseases and drug treatments. Because pharmacology role-play is based on cases presented in advance and active learning through communication, named Case & Communication based approach (C&C approach). Pharmacology role-play was started in 2010 at the University of Miyazaki, it has been shared by 28 schools in 4 faculties of medicine, pharmacy, dentistry, and nursing (23 medical schools, 1 pharmaceutical school, 2 dental schools, and 2 nursing universities) over the 13 years until 2022. Although it is a common program, it is implemented with diversity while devoting various ingenuity according to the characteristics of the University. Pharmacology role-play is effective in (1) understanding of medical treatment, (2) understanding patient’s feelings, (3) improvement of mental attitude and motivation as health professionals (4) positive influence upon study attitude, regardless of universities that conducted the pharmacology role-play. Various efforts include combining with Personal Drugs, developing interprofessional education through joint role-playing by medical students and nursing students, and developing Oriental medicine education through the cases including Kampo medicine. In addition, there are online lectures in response to the Covid-19, and a joint implementation of two universities, all of which are highly effective. The advantage of the multi-institution common program is that a lot of information can be obtained at once, and it is easy to quickly reflect successful ideas. The flexibility and high resilience that can flexibly change the implementation method (face-to-face/remote) according to the situation are also great strengths.
DOI： 10.1254/fpj.22111
Books 【 display / non-display 】
-
赤瀬 智子, 柳田 俊彦（ Role： Supervisor (editorial)）
メディカ出版 2023 （ ISBN:9784840478342 ）
Language：Japanese Book type：Scholarly book
-
柳田 俊彦（ Role： Sole author）
羊土社 2023 （ ISBN:9784758121699 ）
Language：Japanese Book type：Scholarly book
-
知りたいことだけ集めたくすりの"なるほど!" : 日々のギモンを"なるほど!"に変える
柳田 俊彦（ Role： Sole author）
照林社 2023
Language：Japanese Book type：Scholarly book
-
武田 泰生, 齋藤 秀之 (応用薬理学), 伊東 弘樹, 池田 龍二 (医療系薬学), 柳田 俊彦（ Role： Sole author）
南山堂 2023 （ ISBN:9784525500719 ）
Language：Japanese Book type：Scholarly book
-
臨床麻酔インスリンと記憶：海馬におけるその働きと治療へのアプローチ
柳田俊彦、丸田豊明、根本隆行（ Role： Joint author）
真興交易 2020.3
Language：Japanese
MISC 【 display / non-display 】
-
連載 事例で解説!｢この場面｣の"なぜ?"がわかるくすりの知識(第24回)(最終回)アトピー性皮膚炎の患者への投薬 Reviewed
柳田 俊彦
エキスパートナース 41 ( 3 ) 95 - 110 2025.2
Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(株)照林社
-
連載 事例で解説!｢この場面｣の"なぜ?"がわかるくすりの知識(第23回)認知症(アルツハイマー型認知症)患者への投薬 Reviewed
柳田 俊彦
エキスパートナース 41 ( 2 ) 79 - 92 2025.1
Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(株)照林社
-
連載 事例で解説!｢この場面｣の"なぜ?"がわかるくすりの知識(第22回)痛みを訴える患者へのさまざまな投薬 Reviewed
柳田 俊彦
エキスパートナース 41 ( 1 ) 113 - 128 2024.12
Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(株)照林社
-
連載 事例で解説!｢この場面｣の"なぜ?"がわかるくすりの知識(第21回)妊娠している患者への投薬 Reviewed
柳田 俊彦
エキスパートナース 40 ( 15 ) 83 - 94 2024.11
Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(株)照林社
-
連載 事例で解説!｢この場面｣の"なぜ?"がわかるくすりの知識(第20回)腎機能が低下している患者への投薬 Reviewed
柳田 俊彦
エキスパートナース 40 ( 13 ) 103 - 122 2024.10
Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(株)照林社
Presentations 【 display / non-display 】
-
ロールプレイのすゝめ 〜学生主体型 ”医師-患者ロールプレイ” による実践的薬物治療教育の有効性〜（薬理学教育シンポジウム） 次世代の医学部薬理学実習の提案
柳田俊彦
第93回 日本薬理学会年会
Event date： 2020.3.16 - 2020.3.18
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
-
看護における臨床薬理学教育 〜 漢方教育の充実に向けて 〜 Invited
柳田俊彦
第12回 看護学系漢方教育研究会
Event date： 2019.9.28
Language：Japanese Presentation type：Oral presentation (invited, special)
-
薬理学ロールプレイを活用した 漢方医学教育の試み （ランチョンセミナー） Invited
柳田俊彦
第51回 日本医学教育学会大会
Event date： 2019.9.28
Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech
-
看護の視点と薬物治療 〜 看護が変える・看護が変わる 〜(教育講演）
柳田俊彦
看護薬理学カンファレンス2019 in 大阪
Event date： 2019.3.16
Language：Japanese Presentation type：Oral presentation (invited, special)
-
看護師による与薬の質と安全性の向上を目指して- integrated Drug (iDrug)と与薬のしおり- （シンポジウム）与薬の実践者である看護師に必要な薬理学教育とは- 看護師・薬剤師・医師の立場から -
柳田俊彦, 池田龍二, 平原康寿
第92回日本薬理学会年会
Event date： 2019.3.14 - 2019.3.16
Language：Japanese Presentation type：Symposium, workshop panel (public)
Awards 【 display / non-display 】
-
加藤記念バイオサイエンス研究振興財団 研究助成金
2002.5 加藤記念バイオサイエンス研究振興財団
柳田俊彦
Award type：International academic award (Japan or overseas) Country：Japan
-
日本薬理学会年会 優秀発表賞
2002.3 日本薬理学会
柳田 俊彦
Award type：Award from Japanese society, conference, symposium, etc. Country：Japan
-
金原一郎記念医学医療振興財団 研究助成金
2000.9 金原一郎記念医学医療振興財団
柳田俊彦
Award type：Award from publisher, newspaper, foundation, etc. Country：Japan
-
9th International Symposium on Chromaffin Cell Biology Young Investigator Award
1997.5 International Symposium on Chromaffin Cell Biology
Toshihiko Yanagita
Award type：Award from international society, conference, symposium, etc. Country：Japan
Grant-in-Aid for Scientific Research 【 display / non-display 】
-
看護のリアリティとバーチャル融合型シミュレーションプラットフォームの構築
Grant number：23K27870 2024.04 - 2027.03
独立行政法人日本学術振興会 科学研究費基金 基盤研究(B)
Authorship：Coinvestigator(s)
-
実践的看護臨床薬理学教育モデル(iDrug)に基づいた新たな教育システムの開発
Grant number：23K21531 2024.04 - 2025.03
独立行政法人日本学術振興会 科学研究費基金 基盤研究(B)
Authorship：Principal investigator
-
看護のリアリティとバーチャル融合型シミュレーションプラットフォームの構築
Grant number：23H03180 2023.04 - 2027.03
独立行政法人日本学術振興会 科学研究費補助金 基盤研究(B)
Authorship：Coinvestigator(s)
-
実践的看護臨床薬理学教育モデル（iDrug）に基づいた新たな教育システムの開発
Grant number：21H03223 2021.04 - 2025.03
独立行政法人日本学術振興会 科学研究費補助金 基盤研究(B)
Authorship：Principal investigator
-
神経細胞のインスリン抵抗性：改善因子・増悪因子の同定とその作用機序の解明
Grant number：24500442 2012.04 - 2015.03
科学研究費補助金 基盤研究(C)
Authorship：Principal investigator
神経細胞のインスリン抵抗性：改善因子・増悪因子の同定とその作用機序の解明