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Faculty of Medicine School of Nursing Integrated clinical nursing course |
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Related SDGs |
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YANAGITA Toshihiko
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Degree 【 display / non-display 】
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Doctor (Medicine) ( 1997.3 Miyazaki Medical College )
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) ( 1990.3 Miyazaki Medical College )
Papers 【 display / non-display 】
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Co-occurrence network analysis of learning effects in inter-university online pharmacology role-play
Higashi Youichirou, Liu Shuang, Shimizu Takahiro, Togo Mio, Mogi Masaki, Yanagita Toshihiko, Saito Motoaki
Folia Pharmacologica Japonica 161 ( 1 ) 38 - 44 2026.1
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：The Japanese Pharmacological Society
Pharmacology role-play is a participatory learning exercise in which students take on the roles of healthcare providers and patients or family members, explaining diseases and pharmacological treatments based on presented case scenarios, and actively learning through mutual communication. Traditionally conducted face-to-face within a single university, this exercise has shifted to online formats during the COVID-19 pandemic, and more recently, attempts have been made to implement inter-university online sessions that utilize remote collaborative learning. In this study, we compared the educational outcomes of online role-play conducted independently at Kochi University and Ehime University in 2020 with those of an inter-university online role-play jointly conducted by both universities in 2021. Participants were third-year medical students at Kochi University and second-year medical students at Ehime University. After completing all assignments, students were asked to complete a post-session questionnaire. Five-point Likert scale responses were analyzed, and free-text comments were further examined using text mining with co-occurrence network analysis. The results indicated that inter-university role-play, compared with single-university sessions, facilitated the recognition of diverse perspectives and promoted deeper reflection through discussion. This experience contributed to enhanced understanding of patients’ perspectives, increased motivation for becoming physicians, and improved learning attitudes. These findings suggest that inter-university online role-play is an effective educational approach for enhancing learning outcomes in pharmacology education.
DOI： 10.1254/fpj.25063
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看護師に必要な薬理学・臨床薬理学教育とは ～8年の時を経て～
柳田 俊彦
日本薬理学雑誌 160 ( 4 ) 227 - 228 2025.7
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：公益社団法人 日本薬理学会
DOI： 10.1254/fpj.25036
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丸田 豊明, 日髙 康太郎, 越田 智広, 黒木 未央, 鹿毛 陽子, 三浦 綾子, 中川 光, 柳田 俊彦, 武谷 立, 恒吉 勇男
Plos One 20 ( 5 ) e0323628 2025.5
Language：English Publishing type：Research paper (scientific journal) Publisher：Public Library of Science (PLoS)
Neuropathic pain has a significant social impact, with high morbidity and reduced productivity, the underlying mechanisms of neuropathic pain remain poorly understood, and effective therapeutic strategies remain elusive. The development of animal models of neuropathic pain that stimulate only the nociceptors and not the other sensory receptors or motor nerves is desirable for elucidating the complex pathogenesis of neuropathic pain. We have previously reported the generation of NaV1.7−channelrhodopsin-2 (ChR2), NaV1.8−ChR2, and NaV1.9−ChR2 mice. Optogenetics was employed in these light-responsive pain mice for generating nociceptive pain by specifically exciting the spinal dorsal root ganglion neurons, in which the respective Na+ channels are expressed through exposure to blue light. This study aimed to compare the neuropathic pain produced by the prolonged exposure of light-responsive pain mice to blue light. A reversible neuropathic pain state was established persisting for a minimum of 24 hours when each light-responsive pain mouse was irradiated with light of an intensity that consistently elicited pain. Furthermore, the mice also showed pain sensitivity to light irradiation and mechanical stimulation. The expression of c-Fos, a marker for neuronal activity following noxious stimulation, was increased in the dorsal horn of the spinal cord on the light irradiated side. DS-1971a, a selective NaV1.7 inhibitor, was effective in attenuating neuropathic pain in all light-responsive pain mice. In conclusion, optogenetics helps elucidate the specific functions of sodium channel subtypes in pain signaling, thereby advancing our understanding and paving the way for the development of further effective treatments for pain disorders in the future.
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Kouroki S., Maruta T., Hidaka K., Koshida T., Kurogi M., Kage Y., Miura A., Nakagawa H., Yanagita T., Takeya R., Tsuneyoshi I.
Plos One 20 ( 5 May ) e0323628 2025.5
Language：English Publishing type：Research paper (scientific journal) Publisher：Plos One
Neuropathic pain has a significant social impact, with high morbidity and reduced productivity, the underlying mechanisms of neuropathic pain remain poorly understood, and effective therapeutic strategies remain elusive. The development of animal models of neuropathic pain that stimulate only the nociceptors and not the other sensory receptors or motor nerves is desirable for elucidating the complex pathogenesis of neuropathic pain. We have previously reported the generation of Na<inf>V</inf>1.7−channelrhodopsin-2 (ChR2), Na<inf>V</inf>1.8−ChR2, and Na<inf>V</inf>1.9−ChR2 mice. Optogenetics was employed in these light-responsive pain mice for generating nociceptive pain by specifically exciting the spinal dorsal root ganglion neurons, in which the respective Na<sup>+</sup> channels are expressed through exposure to blue light. This study aimed to compare the neuropathic pain produced by the prolonged exposure of light-responsive pain mice to blue light. A reversible neuropathic pain state was established persisting for a minimum of 24 hours when each light-responsive pain mouse was irradiated with light of an intensity that consistently elicited pain. Furthermore, the mice also showed pain sensitivity to light irradiation and mechanical stimulation. The expression of c-Fos, a marker for neuronal activity following noxious stimulation, was increased in the dorsal horn of the spinal cord on the light irradiated side. DS-1971a, a selective Na<inf>V</inf>1.7 inhibitor, was effective in attenuating neuropathic pain in all light-responsive pain mice. In conclusion, optogenetics helps elucidate the specific functions of sodium channel subtypes in pain signaling, thereby advancing our understanding and paving the way for the development of further effective treatments for pain disorders in the future.
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巻頭言 Reviewed
柳田 俊彦
エキスパートナース 41 ( 6 ) 3 - 3 2025.4
Publishing type：Research paper (scientific journal) Publisher：(株)照林社
Books 【 display / non-display 】
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赤瀬 智子, 柳田 俊彦（ Role： Supervisor (editorial)）
メディカ出版 2023 （ ISBN:9784840478342 ）
Language：Japanese Book type：Scholarly book
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柳田 俊彦（ Role： Sole author）
羊土社 2023 （ ISBN:9784758121699 ）
Language：Japanese Book type：Scholarly book
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知りたいことだけ集めたくすりの"なるほど!" : 日々のギモンを"なるほど!"に変える
柳田 俊彦（ Role： Sole author）
照林社 2023
Language：Japanese Book type：Scholarly book
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武田 泰生, 齋藤 秀之 (応用薬理学), 伊東 弘樹, 池田 龍二 (医療系薬学), 柳田 俊彦（ Role： Sole author）
南山堂 2023 （ ISBN:9784525500719 ）
Language：Japanese Book type：Scholarly book
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臨床麻酔インスリンと記憶：海馬におけるその働きと治療へのアプローチ
柳田俊彦、丸田豊明、根本隆行（ Role： Joint author）
真興交易 2020.3
Language：Japanese
MISC 【 display / non-display 】
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連載 事例で解説!｢この場面｣の"なぜ?"がわかるくすりの知識(第24回)(最終回)アトピー性皮膚炎の患者への投薬 Reviewed
柳田 俊彦
エキスパートナース 41 ( 3 ) 95 - 110 2025.2
Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(株)照林社
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連載 事例で解説!｢この場面｣の"なぜ?"がわかるくすりの知識(第23回)認知症(アルツハイマー型認知症)患者への投薬 Reviewed
柳田 俊彦
エキスパートナース 41 ( 2 ) 79 - 92 2025.1
Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(株)照林社
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連載 事例で解説!｢この場面｣の"なぜ?"がわかるくすりの知識(第22回)痛みを訴える患者へのさまざまな投薬 Reviewed
柳田 俊彦
エキスパートナース 41 ( 1 ) 113 - 128 2024.12
Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(株)照林社
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連載 事例で解説!｢この場面｣の"なぜ?"がわかるくすりの知識(第21回)妊娠している患者への投薬 Reviewed
柳田 俊彦
エキスパートナース 40 ( 15 ) 83 - 94 2024.11
Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(株)照林社
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連載 事例で解説!｢この場面｣の"なぜ?"がわかるくすりの知識(第20回)腎機能が低下している患者への投薬 Reviewed
柳田 俊彦
エキスパートナース 40 ( 13 ) 103 - 122 2024.10
Publishing type：Rapid communication, short report, research note, etc. (scientific journal) Publisher：(株)照林社
Presentations 【 display / non-display 】
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ロールプレイのすゝめ 〜学生主体型 ”医師-患者ロールプレイ” による実践的薬物治療教育の有効性〜（薬理学教育シンポジウム） 次世代の医学部薬理学実習の提案
柳田俊彦
第93回 日本薬理学会年会
Event date： 2020.3.16 - 2020.3.18
Language：Japanese Presentation type：Symposium, workshop panel (nominated)
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看護における臨床薬理学教育 〜 漢方教育の充実に向けて 〜 Invited
柳田俊彦
第12回 看護学系漢方教育研究会
Event date： 2019.9.28
Language：Japanese Presentation type：Oral presentation (invited, special)
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薬理学ロールプレイを活用した 漢方医学教育の試み （ランチョンセミナー） Invited
柳田俊彦
第51回 日本医学教育学会大会
Event date： 2019.9.28
Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech
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看護の視点と薬物治療 〜 看護が変える・看護が変わる 〜(教育講演）
柳田俊彦
看護薬理学カンファレンス2019 in 大阪
Event date： 2019.3.16
Language：Japanese Presentation type：Oral presentation (invited, special)
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看護師による与薬の質と安全性の向上を目指して- integrated Drug (iDrug)と与薬のしおり- （シンポジウム）与薬の実践者である看護師に必要な薬理学教育とは- 看護師・薬剤師・医師の立場から -
柳田俊彦, 池田龍二, 平原康寿
第92回日本薬理学会年会
Event date： 2019.3.14 - 2019.3.16
Language：Japanese Presentation type：Symposium, workshop panel (public)
Awards 【 display / non-display 】
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加藤記念バイオサイエンス研究振興財団 研究助成金
2002.5 加藤記念バイオサイエンス研究振興財団
柳田俊彦
Award type：International academic award (Japan or overseas) Country：Japan
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日本薬理学会年会 優秀発表賞
2002.3 日本薬理学会
柳田 俊彦
Award type：Award from Japanese society, conference, symposium, etc. Country：Japan
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金原一郎記念医学医療振興財団 研究助成金
2000.9 金原一郎記念医学医療振興財団
柳田俊彦
Award type：Award from publisher, newspaper, foundation, etc. Country：Japan
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9th International Symposium on Chromaffin Cell Biology Young Investigator Award
1997.5 International Symposium on Chromaffin Cell Biology
Toshihiko Yanagita
Award type：Award from international society, conference, symposium, etc. Country：Japan
Grant-in-Aid for Scientific Research 【 display / non-display 】
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看護のリアリティとバーチャル融合型シミュレーションプラットフォームの構築
Grant number：23K27870 2024.04 - 2027.03
独立行政法人日本学術振興会 科学研究費基金 基盤研究(B)
Authorship：Coinvestigator(s)
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実践的看護臨床薬理学教育モデル(iDrug)に基づいた新たな教育システムの開発
Grant number：23K21531 2024.04 - 2025.03
独立行政法人日本学術振興会 科学研究費基金 基盤研究(B)
Authorship：Principal investigator
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看護のリアリティとバーチャル融合型シミュレーションプラットフォームの構築
Grant number：23H03180 2023.04 - 2027.03
独立行政法人日本学術振興会 科学研究費補助金 基盤研究(B)
Authorship：Coinvestigator(s)
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実践的看護臨床薬理学教育モデル（iDrug）に基づいた新たな教育システムの開発
Grant number：21H03223 2021.04 - 2025.03
独立行政法人日本学術振興会 科学研究費補助金 基盤研究(B)
Authorship：Principal investigator
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神経細胞のインスリン抵抗性：改善因子・増悪因子の同定とその作用機序の解明
Grant number：24500442 2012.04 - 2015.03
科学研究費補助金 基盤研究(C)
Authorship：Principal investigator
神経細胞のインスリン抵抗性：改善因子・増悪因子の同定とその作用機序の解明