Details of a Researcher - TAJIMA Takuya

Risk of Skull Perforation with Halo Vest Skull Pins Reviewed

Hamanaka Hideaki, Tajima Takuya, Kurogi Syuji, Higa Kiyoshi, Nagai Takuya, Takahashi Takumi, Matsumoto Takayuki, Chosa Etsuo

Spine Surgery and Related Research 8 ( 5 ) 480 - 484 2024

Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：The Japanese Society for Spine Surgery and Related Research

Introduction: A halo vest is an immobilization device widely used to stabilize the cervical spine. Pain and infection at the skull pin insertion site are common complications, but skull perforation is rare, and most published studies are case reports. This study aimed to identify risk factors for skull perforation by comparing patients who did and did not develop perforation.Methods: Overall thickness and the thicknesses of the internal and external laminae of the skull at the skull pin insertion sites were measured on cranial computed tomography scans of 66 patients fitted with a halo vest. The results were compared between patients who did and did not develop perforation.Results: Four patients developed perforations. All patients with perforation were older women, and their external and internal laminae were significantly thinner than those of patients who did not develop perforation.Conclusions: The reported causes of skull pin perforation include infection around the pin, osteoporosis, and an enlarged frontal sinus. However, most patients with perforation in the present study were older women, and the cause was the thinning of the external and external laminae.

DOI： 10.22603/ssrr.2023-0261

3．ジャパンラグビーリーグワンにおける外傷・障害調査 Reviewed

田島卓也, 帖佐悦男, 中村明彦

日本臨床スポーツ医学会誌 32 ( 3 ) 342 - 344 2024

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：一般社団法人日本臨床スポーツ医学会

DOI： 10.57474/jjcsm.32.3_342

Spatiotemporal gait characteristics post-total hip arthroplasty and its impact on locomotive syndrome: a before-after comparative study in hip osteoarthritis patients Reviewed

Miyazaki S., Fujii Y., Tsuruta K., Yoshinaga S., Hombu A., Funamoto T., Sakamoto T., Tajima T., Arakawa H., Kawaguchi T., Nakatake J., Chosa E.

Peerj 12 ( 10 ) e18351 2024

Authorship：Lead author,　Last author,　Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Peerj

Background. Understanding the gait pattern of patients eligible for total hip arthroplasty (THA) due to hip osteoarthritis (OA) offers valuable information for improving locomotive syndrome (LS). This study aims to measure the gait patterns of THA-eligible patients using an optical motion capture system and to analyze these patterns using principal component analysis (PCA). Additionally, this study examines the relationship between THA-induced gait patterns and LS. Methods. This before-after study included 237 patients who underwent unilateral primary THA due to hip OA. The primary outcome measures were spatiotemporal gait parameters. Secondary outcome measures included three LS risk tests: a stand-up test, a two-step test, a 25-question Geriatric Locomotive Function Scale (GLFS-25), and total clinical decision limits stages. PCA was performed using 16 spatiotemporal gait parameters collected before and three months after THA. Principal components (PC) were selected to achieve a cumulative contribution rate of 90% (0.9) or higher. Each summarized PC was compared using a paired t-test before and three months after THA. Furthermore, multiple regression analysis was conducted to determine how changes in each PC between before and three months after THA related to changes in the four LS evaluation items. Results. PCA identified three principal components (PC1, PC2, PC3) that accounted for a cumulative contribution rate of 0.910 using 16 spatiotemporal gait parameters. When comparing before and three months after THA for all three PCs, significant differences were observed in each PC (p < 0.001), with overall walking ability and stance phase being higher three months after THA than before THA, while the asymmetry of support time was lower three months after THA. The results of multiple regression analysis revealed that PC1, PC2, and PC3 were the most influential factors in total clinical decision limits stage. For each LS risk test, the factors related to the stand-up test were identified as PC1, PC2, and PC3, while the factors related to the two-step test were identified as PC1 and PC2. The factors related to the GLFS-25 were also identified as PC1 and PC2. Conclusions. The most important findings of this study indicate that the three PCs represent over 90% of the 16 spatiotemporal gait parameters, which are associated with total clinical decision limits stage and LS risk tests. The present results suggest that PC1 represents overall walking ability, PC2 represents the stance phase, and PC3 represents asymmetry of support time. Gait pattern characteristics, such as overall walking ability, stance phase, and asymmetry of support time, were clearly defined by these PCs. Regarding the relationship between PC and LS, all three PCs are related to total clinical decision limits stage. In addition, PC1 and PC2 related to all three LS risk tests, and PC3 related only to the stand-up test.

DOI： 10.7717/peerj.18351

Age- and sex-related differences in upper-body joint and endpoint kinematics during a drinking task in healthy adults. Reviewed

Jun Nakatake, Hideki Arakawa, Takuya Tajima, Shigeaki Miyazaki, Etsuo Chosa

PeerJ 2023.12

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.7717/peerj.16571

Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway Reviewed

Nagai T., Sekimoto T., Kurogi S., Ohta T., Miyazaki S., Yamaguchi Y., Tajima T., Chosa E., Imasaka M., Yoshinobu K., Araki K., Araki M., Choijookhuu N., Sato K., Hishikawa Y., Funamoto T.

Scientific Reports 13 ( 1 ) 14639 2023.12

Language：English Publishing type：Research paper (scientific journal) Publisher：Scientific Reports

Bone remodeling is an extraordinarily complex process involving a variety of factors, such as genetic, metabolic, and environmental components. Although genetic factors play a particularly important role, many have not been identified. In this study, we investigated the role of transmembrane 161a (Tmem161a) in bone structure and function using wild-type (WT) and Tmem161a-depleted (Tmem161aGT/GT) mice. Mice femurs were examined by histological, morphological, and bone strength analyses. Osteoblast differentiation and mineral deposition were examined in Tmem161a-overexpressed, -knockdown and -knockout MC3T3-e1 cells. In WT mice, Tmem161a was expressed in osteoblasts of femurs; however, it was depleted in Tmem161aGT/GT mice. Cortical bone mineral density, thickness, and bone strength were significantly increased in Tmem161aGT/GT mice femurs. In MC3T3-e1 cells, decreased expression of alkaline phosphatase (ALP) and Osterix were found in Tmem161a overexpression, and these findings were reversed in Tmem161a-knockdown or -knockout cells. Microarray and western blot analyses revealed upregulation of the P38 MAPK pathway in Tmem161a-knockout cells, which referred as stress-activated protein kinases. ALP and flow cytometry analyses revealed that Tmem161a-knockout cells were resistant to oxidative stress. In summary, Tmem161a is an important regulator of P38 MAPK signaling, and depletion of Tmem161a induces thicker and stronger bones in mice.

DOI： 10.1038/s41598-023-41837-4

Diagnostic utility of anteroposterior measurements of the median nerve on sagittal ultrasonographic images and their correlation with clinical findings in carpal tunnel syndrome. Reviewed

Okura T, Tajima T, Fukuda H, Matsuoka T, Chosa E

Journal of clinical ultrasound : JCU 2023.10

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1002/jcu.23584

第2趾DIP関節脱臼に対する観血的整復術後の早期スポーツ復帰の一例 Reviewed

Remnant-Preserved Single-Bundle Anterior Cruciate Ligament Augmentation in Multi-ligamentous Knee Reconstruction. Reviewed

Tajima T, Yamaguchi N, Morita Y, Yokoe T, Nagasawa M, Ota T, Kawagoe S, Nakamura Y, Chosa E.

J Knee Surg 36 ( 10 ) 1095 - 1101 2023.10

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.1055/s-0042-1749603

川越亮, 田島卓也, 山口奈美, 大田智美, 長澤誠, 森田雄大, 横江琢示, 帖佐悦男

整形外科と災害外科 72 ( 3 ) 485 - 487 2023.9

Language：Japanese Publishing type：Research paper (scientific journal) Publisher：西日本整形・災害外科学会

【はじめに】観血的整復術を必要とした第2趾のDIP関節脱臼の1例を経験した．【症例】16歳男性．空手中に受傷．第2趾DIP関節脱臼で徒手整復を行ったが整復不能であったため，観血的整復術を行った．整復阻害因子は長趾屈筋腱であり，蹠側板の嵌頓は認めなかった．術後早期の競技復帰希望があったため母趾とのbuddy tapingを指示し復帰とした．術後6か月が経過し特に問題なく競技継続している．【考察】DIP関節脱臼の整復阻害因子は蹠側板や長趾屈筋腱の報告があり，本症例では長趾屈筋腱であった．また，術後のスポーツ復帰について，競技によっては症状次第で早期復帰が見込めると考えられた．

DOI： 10.5035/nishiseisai.72.485

Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway Reviewed

Takuya Nagai,Tomohisa Sekimoto,Syuji Kurogi,Tomomi Ohta, Shihoko Miyazaki,Yoichiro Yamaguchi,Takuya Tajima, Etsuo Chosa,Mai Imasaka,Kumiko Yoshinobu,Yoshitaka Hishikawa,Taro Funamoto

Scientific reports ( 14639 ) 2023.9

Language：English Publishing type：Research paper (bulletin of university, research institution)

DOI： doi.org/10.1038/s41598-023-41837-4

私論学会で発表することの意義 Reviewed

田島卓也

整形外科 74 ( 10 ) 1072 - 1072 2023.9

Publishing type：Research paper (scientific journal) Publisher：南江堂

DOI： 10.15106/j_seikei74_1072

Is the Small Ossicle of Type 1 Accessory Navicular a Cause of Foot Pain?-A Case Report. Reviewed

Yokoe T, Uemichi K, Tajima T, Chosa E

Medicina (Kaunas, Lithuania) 59 ( 9 ) 2023.8

Language：English Publishing type：Research paper (scientific journal)

DOI： 10.3390/medicina59091562

Is the Small Ossicle of Type 1 Accessory Navicular a Cause of Foot Pain?—A Case Report Reviewed

Takuji Yokoe,Kazushi Uemichi,Takuya Tajima,Etsuo Chosa

medicina 59 ( 9 ) 1562 2023.8

Language：English Publishing type：Research paper (bulletin of university, research institution)

DOI： doi.org/10.3390/medicina59091562

Risk factors associated with throwing injuries in young baseball players Reviewed

長澤誠, 田島卓也, 山口奈美, 森田雄大, 横江琢示, 大田智美, 石田康行, 帖佐悦男

Journal of Shoulder and Elbow Surgery 32 ( 8 ) 1673 - 1680 2023.8

Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier

Background
Few studies have retrospectively analyzed the relationship between joint range of motion (ROM) and muscle flexibility and shoulder and elbow throwing injuries in a large number of elementary school baseball players. The purpose of this study was to retrospectively identify the physical factors related to shoulder and elbow throwing injuries in younger baseball players.

Methods
A total of 2466 younger baseball players belonging to our Prefecture Rubber Baseball Federation who participated in medical check-ups from 2016 to 2019 were analyzed. Players completed a questionnaire and had a medical check-up that included a physical examination and ultrasonography. ROM (internal rotation [IR] angle and external rotation angle) of the shoulder and hip and the finger-to-floor distance and heel-to-buttock distance were measured. The straight leg raise was also performed. The results of two groups (normal group and injury group) were compared using the χ2 test, Mann-Whitney U test, and Student t test. Stepwise forward logistic regression models were developed to identify risk factors.

Results
On univariate analysis, nine of the 13 evaluated items showed significant decreases in ROM and muscle flexibility in the injury group. On multiple logistic regression analysis, grade, finger-to-floor distance, IR angle of the dominant side shoulder, and IR angle of the nondominant side hip were significantly associated with the occurrence of throwing injuries. Decreased total shoulder angle was observed not only on the dominant side but also on the nondominant side in the injury group.

Conclusion
Decreased ROM and muscle flexibility were risk factors for baseball-related throwing injuries in elementary school baseball players. To prevent shoulder and elbow throwing injuries, players, coaches, medical staff, and parents need to be aware of these findings.

Shear stress in the medial meniscus posterior root during daily activities.

Yokoe T, Ouchi K, Yamaguchi Y, Enzaki M, Tajima T, Chosa E

The Knee 43 176 - 183 2023.7

Language：English Publishing type：Research paper (scientific journal) Publisher：Knee

Background: Medial meniscus posterior root (MMPR) tears have been reported to occur in middle-aged patients with minor trauma. However, the injury mechanism of MMPR tears remains unclear. The purpose of this study was to evaluate the shear stress in the MMPR during daily activities using a finite-element analysis. Methods: Subject-specific finite-element models of the knee joint of a healthy middle-aged subject were developed from computed tomographic and magnetic resonance images. A three-dimensional motion capture system “VICON” was used to capture four daily activities: walking, jogging, descending stairs, and landing. The knee joint reaction force was estimated using the AnyBody modeling system. Based on these procedures, the shear stress in the MMPR was calculated during each motion. The shear stress in the lateral meniscus posterior root (LMPR) was also measured to compare the stress between the MMPR and LMPR. Results: The shear stress in the MMPR increased as the knee flexion angle increased during each motion. Descending stairs caused more than two-fold greater stress in the MMPR than walking and a similar or greater amount of stress than jogging. The LMPR tended to receive more shear stress than the MMPR throughout each motion. Conclusions: The present study showed that descending stairs confers almost the same amount of shear stress to the MMPR as jogging. The results of the present study may suggest that descending motion of the knee is an important cause of MMPR tear, and the initiation of descending stairs should be delayed after MMPR repair.

DOI： 10.1016/j.knee.2023.06.008