Papers - TAJIMA Takuya
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交通外傷による下腿切断症例における膝関節靭帯断裂と義肢歩行に関する研究－遷延する歩行障害と社会復帰の改善および変形性膝関節症予防を目指して. Reviewed
田島卓也
医研センタージャーナル 5 - 14 2023
Language：Japanese Publishing type：Research paper (scientific journal)
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Risk Factors of Loss of Knee Range of Motion after Primary Anterior Cruciate Ligament Reconstruction following Preoperative Recovery of Knee Range of Motion Reviewed
Takuji Yokoe, Takuya Tajima, Nami Yamaguchi, Yudai Morita, Etsuo Chosa
The Journal of Knee Surgery 2022.12
Language：English Publishing type：Research paper (scientific journal) Publisher：Thieme
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Yokoe T., Tajima T., Kawagoe S., Yamaguchi N., Morita Y., Chosa E.
BMC Musculoskeletal Disorders 23 ( 1 ) 887 2022.12
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：BMC Musculoskeletal Disorders
Background: A number of studies have evaluated risk factors for lateral ankle sprain (LAS) or chronic lateral ankle instability (CLAI). However, the definitive risk factors for LAS or CLAI remain controversial. The purpose of this study was to evaluate whether the contralateral healthy ankles of subjects with ipsilateral mechanical lateral ankle laxity (group I) show greater lateral ankle laxity in comparison to the healthy ankles of bilateral healthy controls (group B). Methods: From March 2020, anterior talofibular ligament (ATFL) lengths of young adult volunteers were cross-sectionally measured in non-stress and stress positions using a previously reported stress ultrasonography (US) procedure. The ATFL ratio (the ratio of stress ATFL/non-stress ATFL length) was calculated as an indicator of lateral ankle laxity. The manual anterior drawer test (ADT) was also performed. The US findings of healthy ankles from groups I and B were compared. Results: A total of 154 subjects in group B (mean age, 24.5 ± 2.8 years; male/female, 84/70) and 40 subjects in group I (mean age, 24.4 ± 2.3 years; male/female, 26/14) were included in the study. There was no significant difference in the ADT between the groups. There were no significant differences in the non-stress ATFL length (19.4 ± 1.8 vs. 19.3 ± 1.9, p = 0.84), stress ATFL length (20.8 ± 1.8 vs. 20.9 ± 1.9, p = 0.66), length change (1.5 ± 0.6 vs. 1.6 ± 0.6, p = 0.12) and ATFL ratio (1.08 ± 0.03 vs. 1.08 ± 0.03, p = 0.13) between the groups. Conclusion: No significant difference was detected between the contralateral healthy ankles of subjects with ipsilateral mechanical lateral ankle laxity and those of bilateral healthy controls.
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The Results of Orthopaedic Medical Examinations in Adolescent Amateur Weightlifters
Yokoe T., Tajima T., Yamaguchi N., Nagasawa M., Morita Y., Chosa E.
International Journal of Environmental Research and Public Health 19 ( 21 ) 2022.11
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：International Journal of Environmental Research and Public Health
Few studies have reported injuries and physical characteristics in adolescent weightlifters. The purpose of this study was to report the results of orthopaedic medical examinations in adolescent amateur weightlifters that were performed cross-sectionally from 2012 to 2019. The orthopaedic medical examination included physical examinations, generalized joint laxity, muscle and joint tightness, static alignment, muscle volume of the lower extremities, and medial longitudinal arch of the foot (the height from the tip of the navicular tubercle to the ground surface). A questionnaire survey regarding pain in the spine and lower extremities was also performed. A total of 99 adolescent weightlifters were included (male/female, 71/28; mean age, 16.2 ± 0.2 years). A total of 9.1% had received orthopaedic treatments, with spine injuries being the most prevalent. Of those who had not received orthopaedic treatments, 31.1% had pain in the spine or lower extremities (for >4 weeks). There were no significant gender differences in the incidence of pain or positive findings of physical examinations. Female weightlifters had a more reduced dorsiflexion of the ankle joint than male weightlifters (p = 0.02). Male weightlifters had a lower flexibility of the quadriceps than female weightlifters. The results of orthopaedic medical examinations in this study may help clinicians and young weightlifters to prevent injuries in competitive weightlifting.
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The Results of Orthopaedic Medical Examinations in Adolescent Amateur Weightlifters Reviewed
Takuji Yokoe, Takuya Tajima, Nami Yamaguchi, Makoto Nagasawa, Yudai Morita, Etsuo Chosa
International Journal of Environmental Research and Public Health 19 ( 21 ) 13947 2022.10
Language：English Publishing type：Research paper (scientific journal) Publisher：MDPI
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The Results of Orthopaedic Medical Examinations in Adolescent Amateur Weightlifters Reviewed
Takuji Yokoe,Takuya Tajima,Nami Yamaguchi,Makoto Nagasawa,Yudai Morita and Etsuo Chosa
International Journal of Environmental Research and Public Health 19 13947 2022.10
Language：English Publishing type：Research paper (scientific journal) Publisher：International Journal fo Environmental Research and Public Health
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Yokoe T, Tajima T, Yamaguchi N, Morita Y, Chosa E
Medicina (Kaunas, Lithuania) 58 ( 11 ) 2022.10
Language：English Publishing type：Research paper (scientific journal) Publisher：Medicina (Lithuania)
Osteochondral lesion (OCL) of the patellofemoral (PF) joint is not an uncommon cause of knee pain, and surgery is needed when conservative treatment fails. However, there is a lack of evidence regarding the optimal surgical treatment for OCL of the PF joint. Fixation of OCLs using autogenous osteochondral grafts has been reported to be effective for OCL of the knee. However, in this surgical technique, the biomechanical strength of osteochondral grafts may not be sufficient in patients with open physes due to the specific quality of the cartilage and subchondral bone given their age. There is a lack of studies reporting fixation of the OCL located in the PF joint using autogenous osteochondral grafts. We herein report a case of OCL of the femoral intercondylar groove where autogenous osteochondral grafts augmented with bioabsorbable pins were used to fix the lesion in a 14-year-old patient with open physes. Preoperative MRI revealed a completely detached OCL of the intercondylar groove (36 mm × 20 mm). Although a total of four osteochondral grafts were harvested from the non-weightbearing area of the lateral femoral condyle, cartilage detached from one of the grafts. The quality of the osteochondral grafts was considered to be insufficient for stabilization of the OCL; thus, two bioabsorbable pins were additionally inserted following fixation of the lesion using three osteochondral grafts. After two years of follow-up, postoperative functional scores were favorable without knee pain. The present case suggests that fixation of the OCL using autogenous osteochondral grafts may not be appropriate for young patients with open physes.
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Fixation of an Osteochondral Lesion of the Femoral Intercondylar Groove Using Autogenous Osteochondral Grafts and Bioabsorbabale Pins in a Patient with Open Physes:A Case Report Reviewed
Takuji Yokoe,Takuya Tajima,Nami Yamaguchi,Yudai Morita and Etsuo Chosa
medicina 2022.10
Language：English Publishing type：Research paper (scientific journal) Publisher：MDPI
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足部びまん性色素性絨毛結節性滑膜炎に対し，関節鏡下腫瘍切除術を施行した一例
外山 宗樹, 横江 琢示, 田島 卓也, 山口 奈美, 大田 智美, 長澤 誠, 森田 雄大, 川越 秀一, 帖佐 悦男
整形外科と災害外科 71 ( 4 ) 725 - 729 2022.9
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：西日本整形・災害外科学会
【背景】色素性絨毛結節性滑膜炎（Pigmented villonodular Synovitis, PVS）は関節滑膜や腱鞘に発生する比較的稀な良性腫瘍である．多くは膝関節周囲に発生し，足関節発生症例は稀である．今回，足部びまん性PVSに対して関節鏡下腫瘍切除術を行い，良好な短期成績を得た一例を経験したので報告する．【症例】23歳女性．数年前から左足部外側に腫瘤を自覚していたが，放置していた．しかしながら，腫瘤の消退を認めず前医を受診し，PVSの疑いで当科紹介となった．当科では関節鏡下腫瘍切除術を施行した．足関節前方および後足部鏡視下併用で足関節，足関節周囲，距骨下に病変を認め，関節鏡視下に腫瘍を切除した．術後病理診断ではびまん性PVSの診断であった．術後26ヶ月経過し，再発なく経過している．【結語】足部びまん性PVSに対し，足関節前方および後足部鏡視下併用での関節鏡下腫瘍切除術を施行し，良好な短期成績を得た一例を経験した．
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足部びまん性色素性絨毛結節性滑膜炎に対し，関節鏡下腫瘍切除術を施行した一例 Reviewed
外山 宗樹,横江 琢示,田島 卓也,山口 奈美,大田 智美,長澤 誠,森田 雄大,川越 秀一,帖佐 悦男
整形外科と災害外科 71 ( 4 ) 725 - 729 2022.9
Language：Japanese Publishing type：Research paper (other academic) Publisher：西日本整形・災害外科学会
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Head Injury Assessment in the Elite Level Rugby Union in Japan: Review of 3 Seasons
Tajima T., Ota O., Nagayama M., Takahashi M., Yamada M., Ishiyama N., Yoshida I., Takemura M., Hara K., Akama T., Mitsumori N., Higashihara J., Toyama Y., Furuya M., Chosa E., Nakamura A.
International Journal of Sports Medicine 43 ( 10 ) 889 - 894 2022.9
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：International Journal of Sports Medicine
Head Injury Assessment (HIA) is the screening tool for head injury during a rugby game. The purpose of this study was to investigate the epidemiology of HIA in the Japan Rugby Top League (JRTL). The incidences of HIA, defined concussion (per 1,000 player-hours) and repeated concussions were evaluated in three seasons (2016-17, 2017-18, 2018-19; total 360 games). The HIA incidence rates were 12.7 (95% confidence interval 9.5-15.9), 20.8 (16.8-24.9), and 25.0 (20.5-29.5) in each season. HIA-1 criteria 2, which is applied for suspected concussion cases, was performed for 46 cases in the 2016-17 season, 81 cases in the 2017-18 season, and 88 cases in the 2018-19 season. The concussion incidence rates were significantly greater in the 2017-18 season (9.6/1000 player-hours, 95% confidence interval 6.8-12.4) and the 2018-19 season (14.4, 11-17.8) compared to the 2016-17 season (4.8, 2.8-6.8). The number of repeated concussion cases in the same season was 1 in the 2016-17 season and 4 in both the 2017-18 and 2018-19 seasons. This study confirmed significantly higher HIA and concussion incidence rates over time. Although the HIA system might have been established in the three seasons in JRTL, comprehensive management needs to be improved to prevent repeated concussions.
DOI： 10.1055/a-1810-6509
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健常者スポーツ，パラスポーツの相互理解を目指して‐合同メディカルチェックの試み- Reviewed
喜多恒允，田島卓也，横江琢示，森田雄大，長澤誠，山口奈美，帖佐悦男
日本臨床スポーツ医学会誌 30 ( 3 ) 695 - 702 2022.8
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：日本臨床スポーツ医学会
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宮崎県の高校ラグビーにおけるメディカルサポート－３年間の外傷調査－ Reviewed
森田 恭史,今里 浩之,岩佐 一真,横江 琢示,森田 雄大,比嘉 聖,山口 奈美,中村 嘉宏,田島 卓也,帖佐 悦男,吉川 大輔
九州・山口スポーツ医・科学研究会誌 33 37 - 40 2022.7
Language：Japanese Publishing type：Research paper (conference, symposium, etc.) Publisher：九州・山口スポーツ医・科学研究会
我々は宮崎県で開催されるラグビーの公式戦で要請のあった全試合にマッチデイドクター配備および後方支援病院を整備している．今回，15人制高校ラグビー宮崎県大会の外傷調査を行ったため報告する．
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サーフィン競技会における医療体制の向上と重症事故発生予防を目的とした安全評価法の作成 Reviewed
石田 翔太郎,小島 岳史,帖佐 悦男,田島 卓也
九州・山口スポーツ医・科学研究会誌 33 6 - 11 2022.7
Language：Japanese Publishing type：Research paper (conference, symposium, etc.) Publisher：九州・山口スポーツ医・科学研究会
サーフィンは海上競技であり，陸上競技では助かる脳震盪でさえも死亡事故につながってしまう．そのため安全に競技会を開催するためにはドクター派遣だけではなくライフセーバー，救急車や後方支援病院との連携，AEDの設置が必要となる．しかし現在このような安全対策ができている競技会は少ない．今回安全度向上を目的としてサーフィン競技会専用の宮崎式安全評価法を作成した．
宮崎県では過去10年間で12例のサーフィン中（競技会外）の死亡例が発生しており，競技会中も重大事故が発生しうる．今回作成した評価法を今後の競技会で継続的に使用し、医療体制の向上に努める必要があると考える． -
Miyazaki Shihoko, Funamoto Taro, Sekimoto Tomohisa, Kurogi Syuji, Ohta Tomomi, Nagai Takuya, Tajima Takuya, Imasaka Mai, Yoshinobu Kumiko, Araki Kimi, Araki Masatake, Choijookhuu Narantsog, Hishikawa Yoshitaka, Chosa Etsuo
ACTA HISTOCHEMICA ET CYTOCHEMICA 55 ( 3 ) 99 - 110 2022.6
Language：English Publishing type：Research paper (scientific journal) Publisher：JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY
Epithelial protein lost in neoplasm (EPLIN) is an actin-associated cytoskeletal protein that plays an important role in epithelial cell adhesion. EPLIN has two isoforms: EPLINα and EPLINβ. In this study, we investigated the role of EPLINβ in osteoblasts using EPLINβ-deficient (<i>EPLINβ<sup>GT/GT</sup></i>) mice. The skeletal phenotype of <i>EPLINβ<sup>GT/GT</sup></i> mice is indistinguishable from the wildtype (WT), but bone properties and strength were significantly decreased compared with WT littermates. Histomorphological analysis revealed altered organization of bone spicules and osteoblast cell arrangement, and decreased alkaline phosphatase activity in <i>EPLINβ<sup>GT/GT</sup></i> mouse bones. Transmission electron microscopy revealed wider intercellular spaces between osteoblasts in <i>EPLINβ<sup>GT/GT</sup></i> mice, suggesting aberrant cell adhesion. In <i>EPLINβ<sup>GT/GT</sup></i> osteoblasts, α- and β-catenins and F-actin were observed at the cell membrane, but OB-cadherin was localized at the perinuclear region, indicating that cadherin-catenin complexes were not formed. EPLINβ knockdown in MC3T3-e1 osteoblast cells showed similar results as in calvaria cell cultures. Bone formation markers, such as <i>RUNX2</i>, <i>Osterix</i>, <i>ALP</i>, and <i>Col1a1</i> mRNA were reduced in EPLINβ knockdown cells, suggesting an important role for EPLINβ in osteoblast formation. In conclusion, we propose that EPLINβ is involved in the assembly of cadherin-catenin complexes in osteoblasts and affects bone formation.
DOI： 10.1267/ahc.22-00027
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EPLINβ Is Involved in the Assembly of Cadherin-catenin Complexes in Osteoblasts and Affects Bone Formation Reviewed
Shihoko Miyazaki, Taro Funamoto, Tomohisa Sekimoto, Syuji Kurigi, Tomomi Ohta, Takuya Nagai, Takuya Tajima, Mai Imasaka, Kumiko Yoshinobu, Kimi Araki, Masatake Asaki, Narantsog Choijookhuu, Yoshitaka Hishikawa, Etsuo Chosa
ACTA HISTOCHEMICA ET CYTOCHEMICA 55 ( 3 ) 99 - 110 2022.6
Language：English Publishing type：Research paper (scientific journal) Publisher：Japan Society of Histochemistry and Cytochemistry
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Remnant-Rreserved Single-Bundle Anterior Cruciate Ligament Augmentation in Multi-ligamentous Knee Reconstruction Reviewed
Takuya Tajima,MD, PhD NamiYamaguchi,MD,PhD Yudai Morita,MD Takuji Yokoe,MD Makotot Nagasawa,MD Tomomi Ota,MD Shuichi Kawagoe,MD Yoshihiro Nakamura, MD Etsuo Chosa,MD,PhD
The Journal of Knee Surgery 2022.6
Language：English Publishing type：Research paper (scientific journal) Publisher：Thieme Medical Publishers,Inc.
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特集 スポーツ外傷･障害の予防と治療--TOKYO 2020が終了して 成長期のスポーツ障害の予防と早期発見のポイント Reviewed
田島 卓也, 帖佐 悦男
医学のあゆみ 281 ( 8 ) 812 - 814 2022.5
Authorship：Lead author, Corresponding author Publishing type：Research paper (scientific journal) Publisher：医歯薬出版
DOI： 10.32118/ayu28108812
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Elective one-stage all four-ligament reconstruction after open knee dislocation: A case report Reviewed
Takuji Yokoe, Takuya Tajima, Nami Yamaguchi, Etsuo Chosa
Journal of Orthopaedic Science 27 ( 3 ) 743 - 749 2022.5
Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier
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A longer duration from injury to surgery is associated with preoperative deterioration of an isolated meniscal tear in patients aged 40 years or older Reviewed
Takuji Yokoe, Takuya Tajima, Nami Yamaguchi, Yudai Morita, Etsuo Chosa
Journal of Orthopaedic Surgery (Hong Kong) 30 ( 2 ) 10225536221101692 2022.5
Language：English Publishing type：Research paper (scientific journal) Publisher：SAGE Publishing