Papers - TAJIMA Takuya
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Age- and sex-related differences in upper-body joint and endpoint kinematics during a drinking task in healthy adults. Reviewed
Jun Nakatake, Hideki Arakawa, Takuya Tajima, Shigeaki Miyazaki, Etsuo Chosa
PeerJ 2023.12
Language:English Publishing type:Research paper (scientific journal)
DOI: 10.7717/peerj.16571
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Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway Reviewed
Nagai Takuya, Sekimoto Tomohisa, Kurogi Syuji, Ohta Tomomi, Miyazaki Shihoko, Yamaguchi Yoichiro, Tajima Takuya, Chosa Etsuo, Imasaka Mai, Yoshinobu Kumiko, Araki Kimi, Araki Masatake, Choijookhuu Narantsog, Sato Katsuaki, Hishikawa Yoshitaka, Funamoto Taro
Scientific Reports 13 ( 1 ) 14639 2023.12
Language:English Publishing type:Research paper (scientific journal)
Bone remodeling is an extraordinarily complex process involving a variety of factors, such as genetic, metabolic, and environmental components. Although genetic factors play a particularly important role, many have not been identified. In this study, we investigated the role of transmembrane 161a (Tmem161a) in bone structure and function using wild-type (WT) and Tmem161a-depleted (Tmem161aGT/GT) mice. Mice femurs were examined by histological, morphological, and bone strength analyses. Osteoblast differentiation and mineral deposition were examined in Tmem161a-overexpressed, -knockdown and -knockout MC3T3-e1 cells. In WT mice, Tmem161a was expressed in osteoblasts of femurs; however, it was depleted in Tmem161aGT/GT mice. Cortical bone mineral density, thickness, and bone strength were significantly increased in Tmem161aGT/GT mice femurs. In MC3T3-e1 cells, decreased expression of alkaline phosphatase (ALP) and Osterix were found in Tmem161a overexpression, and these findings were reversed in Tmem161a-knockdown or -knockout cells. Microarray and western blot analyses revealed upregulation of the P38 MAPK pathway in Tmem161a-knockout cells, which referred as stress-activated protein kinases. ALP and flow cytometry analyses revealed that Tmem161a-knockout cells were resistant to oxidative stress. In summary, Tmem161a is an important regulator of P38 MAPK signaling, and depletion of Tmem161a induces thicker and stronger bones in mice.
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Okura T, Tajima T, Fukuda H, Matsuoka T, Chosa E
Journal of clinical ultrasound : JCU 51 ( 9 ) 1522 - 1528 2023.10
Language:English Publishing type:Research paper (scientific journal) Publisher:Journal of Clinical Ultrasound
Purpose: To investigate the efficacy of sagittal ultrasonography of the median nerve in diagnosing carpal tunnel syndrome (CTS). Methods: Seventy-six hands with idiopathic CTS and 80 hands of asymptomatic subjects were included. All patients with CTS underwent ultrasonographic examination, electrodiagnostic testing, and CTS-6 assessment. In the sagittal ultrasonographic examination, the maximum and minimum median nerve diameters (MNDs) were measured at the proximal and distal ends of the carpal tunnel, respectively. The median nerve stenosis rate (MNSR) was computed as (1 – minimum MND/maximum MND) × 100 (%). The cross-sectional area (CSA) of the median nerve at the level of the pisiform was measured. Results: In the sagittal ultrasonographic examination, the mean maximum MNDs were 0.252 cm and 0.202 cm, mean minimum MNDs were 0.145 cm and 0.165 cm, and mean MNSRs were 41.83% and 17.35% in the CTS and control groups, respectively; the mean maximum MND and MNSR were considerably larger in the CTS group. The maximum MND and MNSR were correlated with the electrodiagnostic testing results and CTS-6 score. The MNSR with a cut-off value of 34.0% had a higher sensitivity and specificity than the CSA in diagnosing CTS. Conclusions: Sagittal ultrasonographic examination is useful in diagnosing CTS.
DOI: 10.1002/jcu.23584
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Remnant-Preserved Single-Bundle Anterior Cruciate Ligament Augmentation in Multi-ligamentous Knee Reconstruction. Reviewed
Tajima T, Yamaguchi N, Morita Y, Yokoe T, Nagasawa M, Ota T, Kawagoe S, Nakamura Y, Chosa E.
J Knee Surg 36 ( 10 ) 1095 - 1101 2023.10
Language:English Publishing type:Research paper (scientific journal)
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第2趾DIP関節脱臼に対する観血的整復術後の早期スポーツ復帰の一例 Reviewed
川越 亮, 田島 卓也, 山口 奈美, 大田 智美, 長澤 誠, 森田 雄大, 横江 琢示, 帖佐 悦男
整形外科と災害外科 72 ( 3 ) 485 - 487 2023.9
Language:Japanese Publishing type:Research paper (scientific journal) Publisher:西日本整形・災害外科学会
【はじめに】観血的整復術を必要とした第2趾のDIP関節脱臼の1例を経験した.【症例】16歳男性.空手中に受傷.第2趾DIP関節脱臼で徒手整復を行ったが整復不能であったため,観血的整復術を行った.整復阻害因子は長趾屈筋腱であり,蹠側板の嵌頓は認めなかった.術後早期の競技復帰希望があったため母趾とのbuddy tapingを指示し復帰とした.術後6か月が経過し特に問題なく競技継続している.【考察】DIP関節脱臼の整復阻害因子は蹠側板や長趾屈筋腱の報告があり,本症例では長趾屈筋腱であった.また,術後のスポーツ復帰について,競技によっては症状次第で早期復帰が見込めると考えられた.
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Tmem161a regulates bone formation and bone strength through the P38 MAPK pathway Reviewed
Takuya Nagai,Tomohisa Sekimoto,Syuji Kurogi,Tomomi Ohta, Shihoko Miyazaki,Yoichiro Yamaguchi,Takuya Tajima, Etsuo Chosa,Mai Imasaka,Kumiko Yoshinobu,Yoshitaka Hishikawa,Taro Funamoto
Scientific reports ( 14639 ) 2023.9
Language:English Publishing type:Research paper (bulletin of university, research institution)
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私論 学会で発表することの意義 Reviewed
田島 卓也
整形外科 74 ( 10 ) 1072 - 1072 2023.9
Publishing type:Research paper (scientific journal) Publisher:南江堂
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Is the Small Ossicle of Type 1 Accessory Navicular a Cause of Foot Pain?-A Case Report. Reviewed
Yokoe T, Uemichi K, Tajima T, Chosa E
Medicina (Kaunas, Lithuania) 59 ( 9 ) 2023.8
Language:English Publishing type:Research paper (scientific journal) Publisher:Medicina Lithuania
Background and objectives: An accessory navicular (AN) bone is often classified into types 1–3 according to the Veitch classification, and symptomatic type 1 patients usually receive non-surgical treatment. However, there are cases in which AN cannot be classified into one of these three types using this classification system, and the small ossicle of type 1 AN may not be the cause of foot pain. This report aimed to present a case of symptomatic type 1 AN that required surgical treatment without the excision of the small ossicle after long-term conservative treatment had failed. Case presentation: A 15-year-old girl who was diagnosed with symptomatic type 1 AN was referred to our department. Medial-side foot pain had prevented her from playing soccer well. She had been treated conservatively for type 1 AN for more than 12 months at several orthopedic clinics. Tenderness of the prominent navicular tubercle was identified, and computed tomography and magnetic resonance imaging findings suggested that the cause of her foot pain was derived from the prominent navicular tubercle not the small ossicle itself. Osteotomy of the prominent navicular tubercle with the advancement of the tibialis posterior tendon, without excision of the ossicle, was performed. At the 12-month follow-up examination, she was completely free from foot pain, and the patient-reported outcome measures were excellent. She now plays soccer at the pre-injury level. Conclusions: We report the case of a patient with symptomatic type 1 AN who underwent osteotomy of the prominent navicular tubercle with advancement of the tibialis posterior tendon, without excision of the ossicle, and who showed favorable short-term clinical outcomes. The evaluation of symptomatic patients with AN based on the Veitch classification alone may lead to inappropriate management. The small ossicle of type 1 AN was not the cause of foot pain in the present case.
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Is the Small Ossicle of Type 1 Accessory Navicular a Cause of Foot Pain?—A Case Report Reviewed
Takuji Yokoe,Kazushi Uemichi,Takuya Tajima,Etsuo Chosa
medicina 59 ( 9 ) 1562 2023.8
Language:English Publishing type:Research paper (bulletin of university, research institution)
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Risk factors associated with throwing injuries in young baseball players Reviewed
長澤 誠, 田島 卓也, 山口 奈美, 森田 雄大, 横江 琢示, 大田 智美, 石田 康行, 帖佐 悦男
Journal of Shoulder and Elbow Surgery 32 ( 8 ) 1673 - 1680 2023.8
Authorship:Corresponding author Language:English Publishing type:Research paper (scientific journal) Publisher:Elsevier
Background
Few studies have retrospectively analyzed the relationship between joint range of motion (ROM) and muscle flexibility and shoulder and elbow throwing injuries in a large number of elementary school baseball players. The purpose of this study was to retrospectively identify the physical factors related to shoulder and elbow throwing injuries in younger baseball players.
Methods
A total of 2466 younger baseball players belonging to our Prefecture Rubber Baseball Federation who participated in medical check-ups from 2016 to 2019 were analyzed. Players completed a questionnaire and had a medical check-up that included a physical examination and ultrasonography. ROM (internal rotation [IR] angle and external rotation angle) of the shoulder and hip and the finger-to-floor distance and heel-to-buttock distance were measured. The straight leg raise was also performed. The results of two groups (normal group and injury group) were compared using the χ2 test, Mann-Whitney U test, and Student t test. Stepwise forward logistic regression models were developed to identify risk factors.
Results
On univariate analysis, nine of the 13 evaluated items showed significant decreases in ROM and muscle flexibility in the injury group. On multiple logistic regression analysis, grade, finger-to-floor distance, IR angle of the dominant side shoulder, and IR angle of the nondominant side hip were significantly associated with the occurrence of throwing injuries. Decreased total shoulder angle was observed not only on the dominant side but also on the nondominant side in the injury group.
Conclusion
Decreased ROM and muscle flexibility were risk factors for baseball-related throwing injuries in elementary school baseball players. To prevent shoulder and elbow throwing injuries, players, coaches, medical staff, and parents need to be aware of these findings. -
Shear stress in the medial meniscus posterior root during daily activities.
Yokoe T, Ouchi K, Yamaguchi Y, Enzaki M, Tajima T, Chosa E
The Knee 43 176 - 183 2023.7
Language:English Publishing type:Research paper (scientific journal) Publisher:Knee
Background: Medial meniscus posterior root (MMPR) tears have been reported to occur in middle-aged patients with minor trauma. However, the injury mechanism of MMPR tears remains unclear. The purpose of this study was to evaluate the shear stress in the MMPR during daily activities using a finite-element analysis. Methods: Subject-specific finite-element models of the knee joint of a healthy middle-aged subject were developed from computed tomographic and magnetic resonance images. A three-dimensional motion capture system “VICON” was used to capture four daily activities: walking, jogging, descending stairs, and landing. The knee joint reaction force was estimated using the AnyBody modeling system. Based on these procedures, the shear stress in the MMPR was calculated during each motion. The shear stress in the lateral meniscus posterior root (LMPR) was also measured to compare the stress between the MMPR and LMPR. Results: The shear stress in the MMPR increased as the knee flexion angle increased during each motion. Descending stairs caused more than two-fold greater stress in the MMPR than walking and a similar or greater amount of stress than jogging. The LMPR tended to receive more shear stress than the MMPR throughout each motion. Conclusions: The present study showed that descending stairs confers almost the same amount of shear stress to the MMPR as jogging. The results of the present study may suggest that descending motion of the knee is an important cause of MMPR tear, and the initiation of descending stairs should be delayed after MMPR repair.
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宮崎式サーフィン競技安全度評価を1シーズン使用してみて Reviewed
小島岳史、柏木輝行、柏木悠吾、福嶋研人、吉田尚紀、石田翔太郎、帖佐悦男、田島卓也
九州・山口 スポーツ医・科学研究会誌 34 28 - 32 2023.7
Language:Japanese Publishing type:Research paper (conference, symposium, etc.) Publisher:Elsevier
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Shear stress in the medial meniscus posterior root during daily activities Reviewed
Takuji Yokoe,Koki Ouchi,Yoichiro Yamaguchi,Masahiro Enzaki, Takuya Tajima,Etsuo Chosa
The Knee 43 176 - 183 2023.6
Language:English Publishing type:Research paper (bulletin of university, research institution) Publisher:Elsevier
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Evaluation of Sit-to-Stand Movement in Older Adults with Locomotive Syndrome Using the Nintendo Wii Balance Board. Sensors Reviewed
Go Yamako, Niroshan G Punchihewa, Hideki Arakawa, Takuya Tajima, Etsuo Chosa
Sensors 2023.5
Language:English Publishing type:Research paper (scientific journal)
DOI: 10.3390/s23073368
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Ureter position and risk of ureteral injury during lateral lumbar interbody fusion Reviewed
Makoto Nagasawa,MD,Takuya Tajima,MD,PhD,Shuichi Kawagoe, MD,Nami Yamaguchi,MD,PhD, Yudai Morita,MD,Takuji Yokoe, MD,Tomomi Ota,MD,Toshihiko Izumi, MD, PhD,Yasuyuki Ishida, MD,Etsuo Chosa,MD,PhD
Journal of Clinical Medicine 32 ( 8 ) 1673 - 1680 2023.5
Language:English Publishing type:Research paper (bulletin of university, research institution) Publisher:Elsevier
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Imazato H, Takahashi N, Hirakawa Y, Yamaguchi Y, Hiyoshi M, Tajima T, Chosa E, Sawaguchi A
Scientific reports 13 ( 1 ) 6352 2023.4
Language:English Publishing type:Research paper (scientific journal) Publisher:Scientific Reports
Recent physiological studies have shown that the deep fascia has received much attention concerning clinical medicine; however, histological examination of the deep fascia has not been well established. In this study, we aimed to clarify and visualize the structure of the deep fascia by taking advantage of cryofixation techniques and low-vacuum scanning electron microscopy. As a result, the ultrastructural observations revealed three-dimensional stratification of the deep fascia composed of three layers: the first superficial layer consisting of collagen fibers extending in various directions with blood vessels and peripheral nerves; the second intermediate layer formed by single straight and thick collagen fibers with flexibility; and the third deepest layer, consisting of relatively straight and thin collagen fibers. We explored the use of two hooks to hold a piece of deep fascia in place through the course of cryo-fixation. A comparative observation with or without the hook-holding procedure would indicate the morphological adaptation to physiological stretch and contraction of the deep fascia. The present morphological approach paves the way to visualize three-dimensional ultrastructures for future biomedical studies including clinical pathophysiology.
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Three‑dimensional fine structures in deep fascia revealed by combined use of cryo‑fixed histochemistry and low‑vacuum scanning microscopy Reviewed
Hiroyuki Imazato,NobuyasuTakahashi,Yusuke Hirakawa, Yoichiro Yamaguchi,Masaru Hiyoshi,Takuya Tajima, Etsuo Chosa, Akira Sawaguchi
Scientific reports 13 ( 1 ) 6352 2023.4
Language:English Publishing type:Research paper (bulletin of university, research institution) Publisher:Springer
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Yamako G, Punchihewa NG, Arakawa H, Tajima T, Chosa E
Sensors (Basel, Switzerland) 23 ( 7 ) 2023.3
Language:English Publishing type:Research paper (scientific journal) Publisher:Sensors
Standing up from a chair is a mechanically demanding daily motion, and its biomechanics represent motor performance. In older adults with locomotive syndrome (LS), sit-to-stand (STS) movement with adequate postural control is essential to prevent falls. This study evaluated the characteristics of dynamic balance during STS movement on older adults with LS. A total of 116 participants aged ≥65 years were divided into Non-LS, LS stage 1, and LS stage 2 groups using the LS risk test. The participants were instructed to stand on the Nintendo Wii Balance Board as quickly as possible, and the STS movement was quantified using the vertical ground reaction force (VGRF) and center of pressure (CoP). The STS score, which represented dynamic balance, was significantly different among the groups (p < 0.001). The rate of VGRF development was significantly lower in the LS stages 1 and 2 than in the Non-LS group (p < 0.001). On the other hand, the total distance of the CoP path did not differ among the groups (p = 0.211). These findings indicated a reduction of postural control in older adults with LS. The STS score emphasized the importance of balance training to prevent falls in older adults with LS.
DOI: 10.3390/s23073368
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Risk factors of failure results after double-bundle reconstruction with autogenous hamstring grafts for isolated posterior cruciate ligament rupture cases Reviewed
Yudai Morita,Takuya Tajima,Nami Yamaguchi,Takuji Yokoe,Makoto Nagasawa,Tomomi Ota,Kouki Ouchi,Etsuo Chosa
Scientific reports 6192 2023.3
Language:English Publishing type:Research paper (bulletin of university, research institution)
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Risk factors of failure results after double-bundle reconstruction with autogenous hamstring grafts for isolated posterior cruciate ligament rupture cases Reviewed
Yudai Morita,Takuya Tajima,Nami Yamaguchi,Takuji Yokoe,Makoto Nagasawa,Tomomi Ota,Kouki Ouchi,Etsuo Chosa
Scientific reports 6192 2023.3
Language:English Publishing type:Research paper (bulletin of university, research institution) Publisher:nature portfolio