論文 - 大澤 健司
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Effect of active immunization of pony mares against recombinant porcine inhibin alpha subunit on ovarian follicular development and plasma steroids and gonadotropins.
Derar RI, Maeda Y, Hoque SM, Osawa T, Watanabe G, Taya K, Miyake Y
The Journal of veterinary medical science 66 ( 1 ) 31 - 5 2004年1月
記述言語：日本語 掲載種別：研究論文（学術雑誌）
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Comparison of the effectiveness of ovulation synchronization protocol in anestrous and cycling beef cows 査読あり
Osawa, T., Morishige, D., Ohta, D., Kimura, Y., Hirata, T-I. and Miyake, Y-I.
Journal of Reproduction and Development 49 ( 6 ) 513 - 521 2003年12月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Comparison of the effectiveness of ovulation synchronization protocol in anestrous and cycling beef cows.
Osawa T, Morishige D, Ohta D, Kimura Y, Hirata T, Miyake Y
The Journal of reproduction and development 49 ( 6 ) 513 - 21 2003年12月
記述言語：日本語 掲載種別：研究論文（学術雑誌）
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Endocrinological changes before and after removal of the granulosa theca cell tumor (GTCT) affected ovary in 6 mares 査読あり
Hoque, M.S., Senba H., Tsunoda N., Derar R. I., Watanabe, G., Taya, K., Osawa, T. and Miyake, Y-I.
Journal of Veterinary Medical Science 65 ( 8 ) 887 - 891 2003年8月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Endocrinological changes before and after removal of the granulosa theca cell tumor (GTCT) affected ovary in 6 mares.
Hoque S, Senba H, Tsunoda N, Derar RI, Watanabe G, Taya K, Osawa T, Miyake Y
The Journal of veterinary medical science 65 ( 8 ) 887 - 91 2003年8月
記述言語：日本語 掲載種別：研究論文（学術雑誌）
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Spontaneous repair of the atrophic contaralateral ovary without ovariectomy in the case of a granulosa theca cell tumor (GTCT) affected mare 査読あり
Hoque, M. S., Derar R. I., Osawa, T., Taya, K., Watanabe, G. and Miyake, Y-I.
Journal of Veterinary Medical Science 65 ( 6 ) 749 - 751 2003年6月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Origin of plasma insulin-like growth factor-I (IGF-I) during estrus in goats 査読あり
Nonaka, S., Hashizume, T., Horiuchi, M., Mikami, U., Osawa, T., Miyake, Y-I. and Hara, S.
Journal of Reproduction and Development 49 ( 3 ) 253 - 258 2003年6月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Localization of inhibin α-, βA- and βB-subunits and aromatase in the ovarian follicles with granulosa theca cell tumor (GTCT) in 6 mares 査読あり
Hoque, M.S., Derar R. I., Senba, H., Osawa, T., Kano, K., Taya, K. and Miyake, Y-I.
Journal of Veterinary Medical Science 65 ( 6 ) 713 - 717 2003年6月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Localization of inhibin alpha-, betaA- and betaB-subunits and aromatase in ovarian follicles with granulosa theca cell tumor (GTCT) in 6 mares. 査読あり
Hoque S, Derar RI, Senba H, Osawa T, Kano K, Taya K, Miyake Y
The Journal of veterinary medical science 65 ( 6 ) 713 - 7 2003年6月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Spontaneous repair of the atrophic contralateral ovary without ovariectomy in the case of a granulosa theca cell tumor (GTCT) affected mare. 査読あり
Hoque S, Derar RI, Osawa T, Taya K, Watanabe G, Miyake Y
The Journal of veterinary medical science 65 ( 6 ) 749 - 51 2003年6月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Origin of plasma insulin-like growth factor-I (IGF-I) during estrus in goats. 査読あり
Nonaka S, Hashizume T, Horiuchi M, Mikami U, Osawa T, Miyake Y, Hara S
The Journal of reproduction and development 49 ( 3 ) 253 - 8 2003年6月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Hoque S., Derar R., Senba H., Osawa T., Kano K., Taya K., Miyake Y.
Journal of Veterinary Medical Science 65 ( 6 ) 713 - 717 2003年6月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Journal of Veterinary Medical Science
To clarify the morphological and immunohistochemical characteristics in mares with granulosa theca cell tumor (GTCT), the localization of inhibin subunits (α, βA, βB) and aromatase in the granulosa cell layers and theca layers in the ovarian follicles were determined by immunohistochemical staining. The follicles were obtained from the ovaries of 6 mares with GTCT and 4 normal mares as controls. Immunohistochemically, inhibin α-subunit was localized in the granulosa cells of all follicles showing different sizes in all GTCT cases and βA- subunit was localized in two GTCT cases in all sized follicles. But inhibin βB- subunit and aromatase were not localized in GTCT cases. On the other hand, inhibin α-, βA-, and βB- subunits and aromatase were localized in the large and medium sized follicles, but inhibin βA- and βB-subunits and aromatase were not stained in the small sized follicles in normal cases. These findings suggest that some mares with GTCT can secrete dimeric inhibin (inhibin A), but all GTCT cases cannot secrete inhibin B. By the results of aromatase staining it is clear that testosterone is not converted into estradiol due to the lack of aromatase in the GTCT follicles.
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Application of timed artificial insemination protocols to grazing Japanese Black cattle with long open period 査読あり
Osawa, T., Morishige, D., Ohta, D., Kimura, Y. and Miyake, Y-I.
Journal of Veterinary Medical Science 65 ( 4 ) 459 - 464 2003年4月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Application of timed artificial insemination protocols to grazing Japanese black cattle with long open period.
Osawa T, Morishige D, Ohta D, Kimura Y, Miyake Y
The Journal of veterinary medical science 65 ( 4 ) 459 - 64 2003年4月
記述言語：日本語 掲載種別：研究論文（学術雑誌）
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乳牛の嚢腫卵胞を伴う繁殖障害の３症例 –超音波画像およびプロジェステロン値による経過観察–
大澤 健司
岩手県獣医師会報 29 ( 3 ) 87 - 91 2003年
記述言語：日本語 掲載種別：研究論文（学術雑誌）
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Seroprevalence of Neospora caninum infection in dairy and beef cattle in Paraguay 査読あり
Osawa, T., Wastling, J., Acosta, L., Ortellado, C., Ibarra, J. and Innes, E. A.
Veterinary Parasitology 110 17 - 23 2002年12月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Seroprevalence of Neospora caninum infection in dairy and beef cattle in Paraguay. 査読あり
Osawa T, Wastling J, Acosta L, Ortellado C, Ibarra J, Innes EA
Veterinary parasitology 110 ( 1-2 ) 17 - 23 2002年12月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Clinical findings before and after the removal of ovaries affected with granulosa theca cell tumor (GTCT) in 16 mares 査読あり
Hoque MD. Shafiqul, Derar R. I., Tsunoda, N., Senba, H., Osawa, T. and Miyake, Y-I.
Journal of Equine Science 13 ( 3 ) 75 - 81 2002年9月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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The peripheral levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), immunoreactive (ir-) inhibin, progesterone (P) and estradiol-17β (E2) at the time of control of ovulation with gonadotropin releasing hormone (GnRH) agonist (Deslorelin) in pony mares. 査読あり
Derar R. I., Maeda, Y., Tsunoda, N., Hoque, M. S., Osawa, T. and Miyake, Y-I.
Journal of Equine Science 13 ( 3 ) 83 - 87 2002年9月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Derar R., Maeda Y., Tsunoda N., Hoque M., Osawa T., Miyake Y.
Journal of Equine Science 13 ( 3 ) 83 - 87 2002年1月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Journal of Equine Science
Control of ovulation in mares obviously has many advantages in a breeding program. Two pony mares were challenged against synthetic Gonadotropin Releasing Hormone (GnRH) agonist (Deslorelin) for six consecutive cycles. Clinical and endocrinological findings after treatment (n=6) with GnRH agonist were compared with those of the control findings before treatment (n=3) of the same mares. The time interval from administration of the GnRH agonist till ovulation (43.5 ±4.0 hr) and the length of the estrous cycle (19.5 ±1.0 days) at the time of treatment were significantly (p < 0.05) shortened as compared with those of the control. A preovulatory sharp rise in plasma luteinizing hormone (LH) and folliclestimulating hormone (FSH) was also noticed 24 hr from the time of GnRH agonist injection and one day prior to ovulation in the studied mares, but there were no significant differences before and after treatment with GnRH agonist on the levels of ir-inhibin, progesterone (P) and estradiol-l7β (E 2 ). It seems likely that GnRH agonist is beneficent in reducing the number of matings needed for conception in a natural mating program and that ovulation in mares may be induced by a sharp preovulatory rise in LH and FSH.