論文 - 河上 洋
-
Kogure H., Kawahata S., Mukai T., Doi S., Iwashita T., Ban T., Ito Y., Kawakami H., Hayashi T., Sasahira N., Kubota K., Togawa O., Kato H., Okabe Y., Matsubara S., Yagioka H., Saito T., Nakai Y., Isayama H.
Endoscopy 52 ( 9 ) 736 - 744 2020年9月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Endoscopy
Background Endoscopic papillary large balloon dilation (EPLBD) has been increasingly used for the management of large common bile duct (CBD) stones. Although EPLBD is often preceded by endoscopic sphincterotomy (EST), EPLBD alone without EST has been increasingly reported as an alternative to EST for large CBD stones. Methods This multicenter randomized trial was conducted at 19 Japanese institutions to compare the efficacy and safety of EPLBD alone versus EST for the removal of large (≥ 10 mm) CBD stones. The primary end point was complete stone removal in a single session. The secondary end points included: Overall complete stone removal, lithotripsy use, procedure time, adverse events, and cost. Results 171 patients with large CBD stones were included in the analysis. The rate of single-session complete stone removal was significantly higher in the EPLBD-alone group than in the EST group (90.7 % vs. 78.8 %; P = 0.04). Lithotripsy use was significantly less frequent in the EPLBD group than in the EST group (30.2 % vs. 48.2 %; P = 0.02). The rates of early adverse events were comparable between the two groups: Rates of overall adverse events were 9.3 % vs. 9.4 % and of pancreatitis were 4.7 % vs. 5.9 % in the EPLBD and EST groups, respectively. The procedure costs were $1442 vs. $1661 in the EPLBD and EST groups, respectively (P = 0.12). Conclusion EPLBD without EST for the endoscopic treatment of large CBD stones achieved a significantly higher rate of complete stone removal in a single session compared with EST, without increasing adverse events.
DOI： 10.1055/a-1145-3377
-
Diarrhea, Fever, and Polyarthralgia with Colitis
Yamamoto S, Miike T, Kawakami H
American Journal of Gastroenterology 115 ( 8 ) 1161 2020年8月
担当区分：最終著者, 責任著者 記述言語：英語 掲載種別：研究論文（学術雑誌） 出版者・発行元：American Journal of Gastroenterology
-
膵・胆管合流異常症
河上 洋
Medical Practice 2020年8月
記述言語：日本語 掲載種別：学位論文（その他）
-
今月の主題 H. pylori未感染胃の上皮性腫瘍 主題 H. pylori未感染胃上皮性腫瘍の臨床的特徴
鈴木 翔, 上堂 文也, 河上 洋, 石原 立
胃と腸 55 ( 8 ) 981 - 987 2020年7月
-
Nanashima, A., Imamura, N., Hiyoshi, M., Hamada, T., Yano, K., Wada, T., Kawakami, H., Ban, T., Kubota ,Y., Sato, Y. and Harada, K.
Clinical Journal of Gastroenterology 13 ( 2 ) 233 - 239 2020年4月
記述言語：英語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Clinical Journal of Gastroenterology
Intraductal papillary neoplasm of the bile duct (IPNB) is defined as a non-invasive malignancy; however, since there are disparities in its histological diagnosis, the operative strategy for typical IPNB has not yet been established. A 69-year-old male was diagnosed with a bile duct mass lesion at the confluence of the cystic duct by ultrasonography without clinical symptoms. Liver functional parameters and tumor markers were within normal ranges. Computed tomography showed an enhanced tumor with no findings of ductal invasion or node metastasis. The tumor was exposed in the hepatic duct lumen and biopsy via SpyGlass DS cholangiography revealed that it was a low-grade papillary lesion, indicating type 1 IPNB. Under preoperative diagnostic modalities, limited resection of the extrahepatic bile duct with D2 lymphadenectomy was planned and R0 resection was achieved. The postoperative histological diagnosis was type 1 IPNB without node metastasis. The postoperative course was uneventful and a good prognosis is expected at this stage. In the field of biliary surgery, although extended resection is generally performed for bile duct carcinomas, satisfactory limited surgical resection is possible for type 1 IPNB with lower malignant behavior.
-
Hiroshi Kawakami, Tadashi Miike, Shojiro Yamamoto, Hiroo Abe, Kazuya Shimoda, Shinya Ashizuka, Haruhiko Inatsu, Yoshimasa Kubota, Tesshin Ban, Kenji Yorita, Hiroaki Kataoka
Internal Medicine 30 ( 3 ) 400 - 402 2020年3月
記述言語：英語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Internal Medicine
Although a few reports of neuroendocrine tumor (NET) in the stomach or appendix with surrounding micronests have been published, cases of rectal NET are rare. We herein report a unique case of a patient with single rectal NET treated endoscopically. A pathological examination revealed multiple endocrine cell micronests (ECMs) in the submucosal layer around the main NET lesion. Neither lymph node metastasis nor distant metastasis in computed tomography was observed six years after the treatment. Because case reports of multiple ECM are very rare, the significance of malignancy is unclear. It therefore appears to be necessary to accumulate similar cases.
-
Kawakami H., Itoi T.
Journal of Hepato-Biliary-Pancreatic Sciences 27 ( 3 ) 149 - 150 2020年3月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Journal of Hepato-Biliary-Pancreatic Sciences
DOI： 10.1002/jhbp.693
-
A novel integrated inside biliary stent and nasobiliary drainage catheter system for biliary drainage (with video). 査読あり
Kawakami H, itoi T.
J Hepatobiliary Pancreat Sci 27 ( 3 ) 149 - 150 2020年3月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
Nanashima A., Hiyoshi M., Imamura N., Hamada T., Nishida T., Kawakami H., Ban T., Kubota Y., Nakashima K., Yano K., Wada T., Takeno S., Kai M.
Clinical Journal of Gastroenterology 13 ( 1 ) 102 - 109 2020年2月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Clinical Journal of Gastroenterology
The efficacy of adjuvant photodynamic therapy (PDT) using the new photosensitizer, talaporfin sodium (TPS) has been clinically examined in some patients with bile duct carcinoma (BDC). Based on our previous cohorts, a prospective clinical trial was attempted; however, only two cases were ultimately enrolled in 27 months. A 664-nm semiconductor laser (100 J/cm2) was applied through an endoscope to the tumor lesion within 6 h of an intravenous injection of 40 mg/m2 TPS according to the protocol for lung cancer. Case 1 was an 82-y.o. female patient with BDC at the left hepatic duct with biliary obstruction, percutaneous transhepatic biliary drainage (PTBD) was achieved, and the patient did not consent to surgery. She was followed up for 15 months to search for non-surgical treatments and eventually received PDT. Although mild photosensitivity occurred, she was discharged without severe adverse events. Biliary stenosis markedly extended and a PTBD tube was scheduled at 1 month. However, cancer immediately metastasized to the liver and she died 155 days after PDT. Case 2 was a 70-y.o. female with perihilar BDC and multiple biliary stenoses. Multiple biliary stenting was considered to be difficult. She received PDT and no adverse events were observed. Biliary stenoses markedly improved and multiple stenting was successfully performed. On day 132, she died of cancer progression. These two cases demonstrated the safety and efficacy of biliary malignant stenosis soon after PDT; however, long-term survival and a sufficient quality of life were not achieved. The combination of the PDT protocol and system chemotherapy or brachytherapy needs to be examined in clinical trials for advanced stage BDC.
-
Kawakami H, Itoi T, Ban T
Journal of Hepato-Biliary-Pancreatic Sciences 27 ( 2 ) E11 - E12 2020年2月
担当区分：筆頭著者, 責任著者 記述言語：英語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Journal of Hepato-Biliary-Pancreatic Sciences
DOI： 10.1002/jhbp.676
-
Intrahepatic biliary stones extraction via an EUS-guided hepaticogastrostomy route confirmed by peroral video cholangioscopy. 査読あり
Kawakami H, Itoi T, Ban T.
J Hepatobiliary Pancreat Sci 27 ( 2 ) E11 - E12 2020年2月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
Kurita A., Yasukawa S., Zen Y., Yoshimura K., Ogura T., Ozawa E., Okabe Y., Asada M., Nebiki H., Shigekawa M., Ikeura T., Eguchi T., Maruyama H., Ueki T., Itonaga M., Hashimoto S., Shiomi H., Minami R., Hoki N., Takenaka M., Itokawa Y., Uza N., Hashigo S., Yasuda H., Takada R., Kamada H., Kawamoto H., Kawakami H., Moriyama I., Fujita K., Matsumoto H., Hanada K., Takemura T., Yazumi S.
Gastrointestinal Endoscopy 91 ( 2 ) 373 - 381.e2 2020年2月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Gastrointestinal Endoscopy
Background and Aims: Histologic diagnosis of autoimmune pancreatitis (AIP) using EUS-guided FNA (EUS-FNA) is difficult. To address this issue, new fine-needle biopsy (FNB) needles were recently developed. Here, we prospectively evaluated 2 newly designed EUS-FNB needles for histologic evaluation in patients with type 1 AIP. Methods: This was a prospective, randomized, multicenter trial comparing biopsy specimens obtained with a 22-gauge Franseen needle or a 20-gauge forward-bevel needle in patients with suspected type 1 AIP. AIP was diagnosed according to international consensus diagnostic criteria. The primary endpoint was the sensitivity of EUS-FNB needles, and secondary endpoints were the amount of specimen obtained, histology of the pancreas based on evaluation of lymphoplasmacytic sclerosing pancreatitis (LPSP), and contribution of histologic findings to the diagnosis of AIP. Results: One hundred ten patients were randomly assigned to the Franseen group (22-gauge Franseen needle) or the forward-bevel group (20-gauge forward-bevel needle). EUS-FNB sampling was successful in all patients. Nine patients were excluded because of diagnoses other than AIP. Compared with the forward-bevel needle, the Franseen needle obtained a significantly greater number of high-power fields. Of 101 patients, 39 patients (78%) in the Franseen group and 23 patients (45%) in the Forward-bevel group were diagnosed with level 1 or 2 LPSP (P =.001). Thirty-six patients could not be diagnosed with type 1 AIP without EUS-FNB specimen results. Conclusions: The 22-gauge Franseen needle should be routinely used for histologic diagnosis of type 1 AIP. (Clinical trial registration number: UMIN 000027668.)
-
胆嚢のヘリコバクター・ピロリ感染と慢性胆嚢炎，胆石のリスク：システマティック・レビューとメタアナリシス
河上 洋
Helicobacter日本語抄訳版 2020年1月
記述言語：日本語 掲載種別：研究論文（学術雑誌）
-
炎症性腸疾患類縁疾患の内視鏡診断
芦塚伸也，山本章二朗，河上 洋
日本消化器内視鏡学会雑誌 2020年1月
記述言語：日本語 掲載種別：研究論文（学術雑誌）
-
Endoscopic ultrasonography-guided fine-needle biopsy from ascending colon using a novel curved linear echoendoscope. 査読あり
Kawakami H, Ban T, Kubota Y, Noda T, Oshikawa K.
Endoscopy 52 ( 1 ) E24 - E26 2020年1月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
ERCP後膵炎発生率の低減を目的としたearlyとprimary precutの無作為化比較試験
河上 洋
日本消化器内視鏡学会雑誌 62 ( 10 ) 2330 - 2330 2020年
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：一般社団法人 日本消化器内視鏡学会
【背景と目的】通常，PrecutはERCP後膵炎（PEP）の危険因子の１つである選択的胆管挿管困難例に対して施行される．近年，primary precutの有用性が報告されているが，これまで報告は少ない．今回はprimary precutの安全性と有用性を評価する目的に研究を計画した．【方法】very early precut群（A群：パピロトームを用いたwire-guided cannulationにより胆管挿管を２回試行しても困難であった群）とprimary precut群（B群：direct precut群）を単施設で無作為化比較試験（RCT）を行った．術者はエキスパートが行い，主要評価項目はPEPの発生率とした．【結果】303例をA：B群＝152：151に割付した．背景やERCPの適応に有意差はなかった．PEP発生率はA：B群＝5.2：0.67％（<i>P</i>＝0.04），高アミラーゼ血症はA：B群＝12.5：2.6％（<i>P</i>＝0.01）とB群で有意に低く，選択的胆管挿管時間はA：B群＝13.8±2.2：7.2±1.7分（<i>P</i>＝0.001）とB群で有意に短時間であった．最終胆管挿管率はA：B群＝98：98.6％（<i>P</i>＝0.001）と両群に有意差はなかった．【結語】エキスパートの内視鏡医によるprimary precutはPEPの発生頻度は低かった．
DOI： 10.11280/gee.62.2330
-
Endoscopic diagnosis of inflammatory bowel disease-related diseases
Ashizuka S., Yamamoto S., Kawakami H.
Gastroenterological Endoscopy 62 ( 1 ) 15 - 33 2020年
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Gastroenterological Endoscopy
The diagnosis of inflammatory bowel disease (IBD) including ulcerative colitis (UC) and Crohn's disease (CD) in the absence of typical endoscopic features is often challenging. In such cases, UC or CD cannot be definitively diagnosed, and these conditions are categorized as "nflammatory bowel disease-unclassified". Recent technological advances have introduced balloon-assisted endoscopy and capsule endoscopy for the management of patients with chronic enteritis. These techniques enable the detection of mucosal lesions in the small intestine. Furthermore, these innovations have changed the diagnostic strategy of IBD and IBD-related diseases. In this review, we present an overview, as well as the clinical characteristics and endoscopic diagnosis of IBD-related diseases including intestinal Behçet's disease with simple ulcer, trisomy 8-associated enteritis, chronic enteropathy associated with the SLCO2A1 gene, and familial Mediterranean fever with enteritis.
DOI： 10.11280/gee.62.15
-
Kawakami H, Ban T, Kubota Y, Noda T, Oshikawa K
Endoscopy 52 ( 1 ) E24 - E26 2020年
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Endoscopy
DOI： 10.1055/a-0982-2688
-
抗血小板薬・抗凝固薬内服患者に対するEUS-FNA
川久保和道，河上 洋，坂本直哉
日本消化器内視鏡学会雑誌 2019年12月
記述言語：日本語 掲載種別：研究論文（学術雑誌）
-
Huge enterolithiasis in Crohn's disease. 査読あり
Hirata T, Kawakami H, Kubota Y.
Clinical Gastroenterology and Hepatology 17 ( 12 ) e141 - e141 2019年12月
記述言語：英語 掲載種別：研究論文（学術雑誌）