Papers - KANEKO Masatoki
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Work environment to achieve work-life balance in workers raising children: A questionnaire survey of young in Miyazaki Cityy Reviewed
21 ( 1 ) 1 - 8 2023.3
Authorship：Corresponding author Language：Japanese Publishing type：Research paper (bulletin of university, research institution)
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A qualitative study of maternal and child health coordinators on mothers' concerns Reviewed
kaho Yamshita, Keiko Yamazaki, Ayaka Matsuoka, Masatoki Kaneko
20 ( 1 ) 9 - 16 2023.3
Authorship：Corresponding author Language：Japanese Publishing type：Research paper (bulletin of university, research institution)
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Kaneko M., Yang L., Tanabe A., Fujii Y., Nakao H., Minematsu T.
Journal of Infection and Chemotherapy 29 485 - 489 2023
Authorship：Lead author, Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Journal of Infection and Chemotherapy
Introduction: Variable rates of cytomegalovirus (CMV) seropositivity in mothers from different individual's background may translate to distinct epidemiological patterns of congenital CMV infection. Methods: The prospective cohort study was conducted in Japan to evaluate the prevalence of vertical transmission rate according to the type of maternal infection. Post hoc power as a follow-up analysis was evaluated to compare the statistical power with other studies from France, Finland and Brazil. One thousand one hundred sixty-three pregnant women were measured IgG, IgM and IgG avidity index. The urine samples of neonates of these women were evaluated using polymerase chain reaction to diagnose the vertical transmission. Results: The prevalence of congenital CMV infection in the study population was 0.4%. The proportions of patients with primary and nonprimary infections were 60% and 40%, respectively, with a maternal seroprevalence of 82.5%. The rate of vertical transmission among the seronegative pregnant women before pregnancy was statistically higher than that among the seropositive pregnant women before pregnancy (p < 0.05), with a study power of 52.7%. The same difference was observed in France and Finland for maternal seroprevalence of 61% and 72% and statistical power of 56.9% and 66.7%, respectively. Conclusion: The maternal seroprevalence of the present study conducted in Japan was much higher than that of studies in France and Finland. Nevertheless, seronegative pregnant women had a higher risk of vertical transmission before pregnancy.
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Sakakibara Kouhei, Yamada Naoshi, Kodama Yuki, Obata Shizuka, Tsuzuki Yasue, Muraoka Junsuke, Aoki Yoshinori, Yamashita Rie, Nakame Kazuhiko, Kaneko Masatoki, Katsuragi Shinji, Tsuzuki Ryo, Sato Yuichiro
Journal of Japan Society of Perinatal and Neonatal Medicine 59 ( 1 ) 116 - 121 2023
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Japan Society of Perinatal and Neonatal Medicine
Here we report a case of pulmonary lymphangiectasia that caused exacerbation of respiratory status after an infection. A preterm infant born at 23 weeks of gestation without obvious clinical intrauterine infection showed worsening respiratory status and increased c-reactive protein on day 15 of life. Chest X-ray showed consolidation in right upper lobe and whole left lung. Several broad-spectrum antibiotics were administered unsuccessfully. Finally, <i>Ureaplasma urealyticum</i> was detected in sputum culture, and azithromycin was administered. Although the inflammation improved, tension pneumothorax and pulmonary hypertension developed and he died on day 44 of life. At autopsy, there were few findings of lung inflammation, and congenital lymphangiectasia was diagnosed. It seems that exacerbation was triggered by the infection, although there was no remarkable evidence to support causality. There have been few case reports of pulmonary lymphangiectasia in extremely low birth weight infants. This case was considered to be classified as primary, although the respiratory condition at birth was relatively good. There are no clear diagnostic criteria for this disease and no effective treatments. Clinically, neonatologists should keep in mind pulmonary lymphangiectasia if respiratory failure in newborns does not respond to common treatment approach.
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先天性感染症
金子 政時
周産期医学 53 1214 - 1216 2023
Publishing type：Research paper (scientific journal)
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増刊号 191の疑問に答える周産期の栄養 産科編Q & A 妊娠中期 Q80 食後の胸焼けがひどくなりました。 食事はどうしたらよいですか? 薬はありますか? Reviewed
金子 政時, 前山 彩, 松岡 あやか
周産期医学 52 ( 13 ) 179 - 180 2022.11
Publishing type：Research paper (scientific journal) Publisher：東京医学社
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Muraoka J., Kaneko M., Doi K., Kodama Y., Sameshima H.
Microbiology Research 13 ( 3 ) 598 - 608 2022.9
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：Microbiology Research
The use of prenatal antibiotics should be carefully considered, owing to their potential adverse effects on neonatal outcomes. This study aimed to identify the contributing factors to early-onset neonatal infection and to determine the influence of antepartum antibiotics on women and neonates. This study included 127 pregnant women without obvious intra-amniotic infection on admission, who delivered under 34 weeks of gestation. Information on maternal and neonatal characteristics was obtained from their medical charts. Vaginal swabs were taken from all women on admission. In total, 29 (22.8%) neonates developed early-onset infection. Multivariate analysis revealed that antepartum antibiotics were the most strongly associated factor for early-onset neonatal infection (odds ratio, 11.2; 95% confidence interval, 4.08–31.02). The frequency of early-onset neonatal infection was significantly higher in women who received antibiotic therapy than in those who did not; no significant difference in prolonging their gestation or neonatal morbidities was observed. The prevalence of women who hosted vaginal microorganisms on admission was similar to that in women whose infants subsequently developed early-onset neonatal infection compared with that of women whose infants did not. Among infants of the 40 women who received antepartum antibiotic therapy, 21 developed early-onset infection. Of the women who delivered these 21 infants, 62% (13/21) showed reduced lactobacilli and 43% (9/21) had resistant bacterial strains in their vaginal microbiota at the time of delivery. The use of antepartum antibiotics is the most strongly associated factor in early-onset neonatal infection; it does not prolong gestation and would change the vaginal environment.
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Antepartum antibiotic therapy under 34 weeks of gestation and its impact on early-onset neonatal infection and maternal vaginal microbiota Reviewed
Masatoki Kaneko
Microbiological Reserch 13 598 - 608 2022.8
Publishing type：Research paper (scientific journal)
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Association between chorioamnionitis severity and procalcitonin levels in umbilical venous blood Reviewed International journal
Masatoki Kaneko, Junsuke Muraoka, Naoshi Yamada, Yuki Kodama
Clinical and Experimental Obstetrics & Gynecology 49 ( 7 ) 160 2022.7
Authorship：Lead author, Corresponding author Language：English Publishing type：Research paper (scientific journal) Publisher：IMR Press
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Association between chorioamnionitis severity and procalcitonin levels in umbilical venous blood Reviewed
Masatoki Kaneko
Clinical and Experimental Obstetrics & Gynecology 49 ( 7 ) 16 2022.7
Publishing type：Research paper (scientific journal)
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先天性サイトメガロウイルス感染症の現状と課題 Invited
金子政時
日本周産期・新生児医学会雑誌 57 ( 4 ) 606 - 609 2022.4
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)
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A comparative study of changes in postural alignment, muscle stiffness around the shoulders over time and between good and bad posture in Cradle-hold position Reviewed
Ai Osaki, Ayaka Matsuoka, Masatoki Kaneko, Keiko Yamazaki
Japanese Journal of Maternal Health 63 ( 1 ) 112 - 120 2022.4
Authorship：Corresponding author Language：Japanese Publishing type：Research paper (scientific journal)
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A survey regarding why the medical staff works while sick -Survey on the working conditions of medical personnel working at tertiary obstetric care facilities when they are sick- Reviewed
20 ( 1 ) 10 - 17 2022.4
Authorship：Corresponding author Language：Japanese Publishing type：Research paper (bulletin of university, research institution)
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Matsuoka Ayaka, Kaneko Masatoki, Imamura Tomomi
The South Kyusyu journal of nursing 20 ( 1 ) 10 - 17 2022.3
Authorship：Corresponding author Language：Japanese Publishing type：Research paper (scientific journal)
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Analysis of the factors affecting parents' hospital visit to their extremely low-birthweight infants in the Neonatal Care Unit Reviewed
Saki Yanagita, Masatoki Kaneko, Keiko Yamazaki, Ayaka Matsuoka
Japanese Journal of Maternal Health 62 ( 4 ) 771 - 778 2022.1
Authorship：Last author Publishing type：Research paper (scientific journal)
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Evaluation of blood collection training in collaboration with clinical nurses Reviewed
KATO Sayaka, SUETSUGU Norie, YOSHINAGA Saori, TSURUTA Kurumi, KANEKO Masatoki
Journal of Japan Association for Simulation-based Education in Healthcare Professionals 10 ( 0 ) 43 - 50 2022
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Japan Association for Simulation-based Education in Healthcare Professionals
This study aimed to clarify the educational value of venous blood collection technique exercises in collaboration with clinical nurses. 52 nursing students were evaluated in their second and fourth years and were asked to complete a self-administered original questionnaire survey. The Wilcoxon signed-rank test was used to compare the results. Most of the self-evaluation scores were higher for the fourth-years compared with the second-years, particularly for factors that can be categorized as “medical security” and “venipuncture maneuver”. In particular, a significantly higher proportion of fourth-years compared to second-years were able to select the appropriate venipuncture site and puncture blood vessels(p < .05). The approach of clinical and university cooperation increased the motivation of nursing students to learn before graduation, suggesting the need for a smooth transition from basic nursing education to continuing practical nursing education.
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特集 周産期医学必修知識(第9版) 性感染症(STI/STD) Reviewed
金子 政時
周産期医学 51 ( 13 ) 9 - 12 2021.12
Publishing type：Research paper (scientific journal) Publisher：(株)東京医学社
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A case of facial cellulitis caused by group B streptococcus in an extremely low birthweight infant Reviewed
Muraoka J., Kodama Y., Higashi M., Yamada N., Yamashita R., Nakame K., Kaneko M., Sameshima H.
Journal of Infection and Chemotherapy 27 ( 9 ) 1369 - 1372 2021.9
Language：English Publishing type：Research paper (scientific journal) Publisher：Journal of Infection and Chemotherapy
Group B streptococcus (GBS) is an important pathogen that causes neonatal sepsis and meningitis, which have high mortality and morbidity. Cellulitis is a rare presentation of late-onset neonatal GBS infection. We report the case of an extremely low birthweight infant with facial cellulitis caused by late-onset GBS infection. A 590-g male neonate was delivered by Cesarean section at 23 gestational weeks due to intrauterine GBS infection. Although he was effectively treated with 2 weeks of antimicrobial therapy for early-onset GBS sepsis, he subsequently developed facial and submandibular cellulitis caused by GBS at 44 days of age. He was treated with debridement and antibiotic therapy, and after 2 months his facial involvement had improved, but cosmetic issues remained. Neonatal GBS infection requires a prompt sepsis workup followed by the initiation of empiric antibiotic therapy. Additionally, lifesaving surgical debridement is sometimes necessary for cellulitis, even in premature infants.
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Congenital Cytomegalovirus Infection and Hearing Loss Invited
Masatoki Kaneko
261 27 - 30 2021.8
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)
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先天性サイトメガロウイルス感染症の胎児診断 Invited
金子 政時
ENTONI 261 27 - 30 2021.8
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)