Papers - KANEKO Masatoki
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Perinatal death and neurological damage as a sequential chain of poor outcome Reviewed
Masatoki Kaneko
The Journal of Maternal-Fetal and Neonatal Medicine 1 - 4 2011.4
Language：English Publishing type：Research paper (scientific journal)
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Kaneko M., Tokunaga S., Mukai M., MacHigashira S., Maki Y., Kodama Y., Sameshima H., Ikenoue T.
Journal of Pediatric Surgery 46 ( 2 ) e37 - 40 2011.2
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Journal of Pediatric Surgery
Fetal monitoring is required to avoid hypoxic injury during ex utero intrapartum treatment (EXIT). We performed a tracheostomy under EXIT in a case of suspected airway obstruction caused by a cervical teratoma. The scalp electrode was applied for continuous fetal heart rate monitoring. This device enabled us to promptly deal with fetal bradycardia caused by cord compression. We describe here the usefulness of the fetal scalp electrode for fetal monitoring under EXIT. Crown Copyright © 2011 Published by Elsevier Inc. All rights reserved.
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町頭 成郎, 松藤 凡, 加治 建, 下野 隆一, 向井 基, 中目 和彦, 枡屋 隆太, 鮫島 浩, 金子 政時, 児玉 由紀, 池ノ上 克
日本小児外科学会雑誌 47 ( 6 ) 2011
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：特定非営利活動法人 日本小児外科学会
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6)一絨毛膜双胎妊娠管理スコア指標とする立場に立って((3)一絨毛膜双胎娩出のタイミング,4)周産期,1.クリニカルディベート,生涯研修プログラム,第63回日本産科婦人科学会学術講演会)
金子 政時
日本産科婦人科學會雜誌 63 ( 2 ) 2011
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：日本産科婦人科学会
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Rubella outbreak on Tokunoshima Island in 2004 : A population-based study of pregnant women
KUSUMOTO Kazumi, KANEKO Masatoki, SAMESHIMA Hiroshi, MINEMATSU Toshio, FURUTA Ken, IKENOUE Tsuyomu
The journal of obstetrics and gynaecology research 36 ( 5 ) 938 - 943 2010.10
Language：Japanese Publishing type：Research paper (scientific journal)
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Clinical factors that enhance morbidity and mortality in intrauterine growth restricted foetuses delivered between 23 and 30 weeks of gestation. Reviewed
Sameshima H, Kodama Y, Kaneko M, Ikenoue T.
Journal of Maternal Fetal neonatal Medicine 23 ( 10 ) 1218 - 1224 2010.10
Language：English Publishing type：Research paper (scientific journal)
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Rubella outbreak on Tokunoshima Island in 2004: a population-based study of pregnat women. Reviewed
Kusumoto K, Kaneko M, Sameshima H, Minematsu T, Furuta K, Ikenoue T
Journal of Obstetrical Gynaecology Resarch 36 ( 5 ) 938 - 943 2010.10
Language：English Publishing type：Research paper (scientific journal)
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Rubella outbreak on Tokunoshima Island in 2004: a population-based study of pregnant women.
Kusumoto K, Kaneko M, Sameshima H, Minematsu T, Furuta K, Ikenoue T
The journal of obstetrics and gynaecology research 36 ( 5 ) 938 - 43 2010.10
Language：Japanese Publishing type：Research paper (scientific journal)
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Sameshima H., Kodama Y., Kaneko M., Ikenoue T.
Journal of Maternal-Fetal and Neonatal Medicine 23 ( 10 ) 1218 - 1224 2010.10
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Journal of Maternal-Fetal and Neonatal Medicine
Objective.To find clinical factors that are associated with poor outcome (death and brain damage) in premature intrauterine growth restricted (IUGR) infants. Methods.A retrospective study was performed to compare the incidence of poor outcome between 45 IUGR and 203 appropriate-for-gestational-age (AGA) infants born before 30 weeks of gestation. Foetal tests included foetal heart rate monitoring, Doppler flow, amniotic fluid, and head circumference. Growth for gestational age was categorised as 10th through 3rd, third through first, and below first percentiles. Results.In infants below 25 weeks of gestation, the incidence of poor outcome was not different between IUGR and AGA. In infants between 25 and 30 weeks of gestation, the incidence of poor outcome was significantly increased in IUGR compared with AGA (12/40, 30 versus 11/136, 8.1, p < 0.01). Univariate analysis showed that abnormality in foetal heart rate monitoring [odds ratio (OR) 8.3, 95 confidence interval (CI) 1.5843.6], head circumference (OR 7.0, 95CI 1.4234.4), and Doppler flow (OR 10.9, 95CI 1.8364.6) was significantly associated with poor outcome in IUGR infants. However, no foetal tests were significantly associated with poor outcome after adjusting for the 3-grade birthweight percentiles. Conclusions.Immaturity outweighs clinical problem associated with IUGR in infants below 25 weeks of gestation. Between 25 and 30 weeks of gestation, there was a growth threshold below third percentile where foetal tests were not significant predictors of poor outcome, but that was primarily determined by birthweight. © 2010 Informa UK, Ltd.
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Developmental changes in catecholamine requirement, volume load and corticosteroid supplementation in premature infants born at 22 to 28 weeks of gestation Reviewed
Kaori Michikata, Hiroshi Sameshima, Kaeko Sumiyoshi, Yuki Kodama, Masatoki Kaneko, Tsuyomu Ikenoue
Early Human Development 86 401 - 405 2010.8
Language：English Publishing type：Research paper (scientific journal)
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Michikata K., Sameshima H., Sumiyoshi K., Kodama Y., Kaneko M., Ikenoue T.
Early Human Development 86 ( 7 ) 401 - 405 2010.7
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Early Human Development
Background: Due to circulatory instability, premature infants require volume loads, catecholamines and steroid supplementation to improve mortality and neurodevelopmental outcome. However, a complete quantitative analysis concerning the relationship between supplementation and gestational age, especially in infants born at 22 to 24 weeks of gestation, is lacking. Aim: To investigate whether less mature infants need higher doses of catecholamine, volume loads and steroid, and whether those who require higher doses have poorer outcome. Study design: A retrospective, observational study was performed at a tertiary center in a university setting. Among the consecutive 221 premature infants born at 22 to 28 weeks of gestation, we selected 108 infants who had no apparent pathological conditions other than prematurity. Catecholamines, volume loads and steroid, given to attain sufficient blood pressure and urinary output, were quantitatively analyzed during the first 24 hours. Outcome measures: Quantity of catecholamines, volume expanders and steroid supplementation as a function of gestational age and childhood outcome at 2 years. Results: Catecholamines and volume loads were increased in a step-wise manner with decreasing gestational age. Intact survival rate was significantly lower in infants born before 25 weeks of gestation compared with the more mature infants. Among infants born at 22 to 24 weeks' gestation, catecholamine and volume load increased significantly in poor outcome infants compared with good outcome infants. Conclusions: From a developmental viewpoint, progressively larger doses of catecholamine, volume expanders and corticosteroid are required to stabilize circulatory adaptation to neonatal life in infants between 22 to 28 weeks of gestation. © 2010 Elsevier Ltd.
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町頭 成郎, 松藤 凡, 加治 建, 向井 基, 堂地 勉, 桑波田 知樹, 川俣 和弥, 池ノ上 克, 鮫島 浩, 金子 政時
日本小児外科学会雑誌 46 ( 3 ) 2010
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：特定非営利活動法人 日本小児外科学会
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P001.胃穿孔を起こした超低出生体重児の1例(一般演題,第47回日本小児外科学会九州地方会)
町頭 成郎, 千々岩 一男, 近藤 千博, 池ノ上 克, 鮫島 浩, 金子 政時
日本小児外科学会雑誌 46 ( 6 ) 2010
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：特定非営利活動法人 日本小児外科学会
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金子 政時
日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 45 ( 4 ) 994 - 997 2009.12
Language：Japanese Publishing type：Research paper (scientific journal)
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A substantive medical education program for students and doctors in collaboration with obstetricians and gynecologist, and pediatricians
45 ( 4 ) 994 - 997 2009.12
Language：Japanese Publishing type：Research paper (scientific journal)
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CMV胎内感染治療の展望 : 予後からみた今後の治療のありかた
丸山 有子, 茨 聡, 金子 政時, 児玉 由紀, 丸山 英樹, 徳久 琢也, 松井 貴子, 藤江 由夏, 中澤 祐介, 上塘 正人, 前田 隆嗣, 鮫島 浩, 池ノ上 克, 栄鶴 義人, 峰松 俊夫, 土井 宏太郎, 加藤 明彦, 寺原 賢人
日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 45 ( 1 ) 5 - 9 2009.4
Language：Japanese Publishing type：Research paper (scientific journal)
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胎内サイトメガロウイルス感染症における抗原血症の臨床上の有用性
金子 政時, SAMESHIMA Hiroshi, IKENOUE Tsuyomu, KUSUMOTO Kazumi, MINEMATSU Toshio
Pediatrics international : official journal of the Japan Pediatric Society 51 ( 1 ) 1 - 4 2009.2
Language：Japanese Publishing type：Research paper (scientific journal)
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Clinical importance of cytomegalovirus antigenemia for intrauterine cytomegalovirus infection. （共著） Reviewed
Masatoki Kaneko, Hiroshi Sameshima, Tsuyomu Ikenoue, Kazumi Kusumoto, Toshio Minematsu.
Pediatrics International 51 1 - 4 2009.2
Language：English Publishing type：Research paper (scientific journal)
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Clinical importance of cytomegalovirus antigenemia for intrauterine cytomegalovirus infection
Kaneko M., Sameshima H., Ikenoue T., Kusumoto K., Minematsu T.
Pediatrics International 51 ( 1 ) 1 - 4 2009.2
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Pediatrics International
Background: Little is known about the clinical importance of cytomegalovirus (CMV) antigenemia for intrauterine-CMV-infected newborns. The aims of the present study were to evaluate the diagnostic accuracy of CMV antigenemia during the neonatal period and its association with clinical manifestations. Methods: CMV antigenemia was analyzed using neonatal blood from 25 patients suspected of having intrauterine infection because of abnormal clinical manifestations in the mother, fetus, and newborn. Neonatal urine samples were collected for diagnosis of intrauterine infection. The diagnostic accuracy of the antigenemia analysis was evaluated by comparing it with the results of urinary CMV analyses. The clinical manifestations of antigenemia-positive and -negative infected newborns were compared in the infected newborns. Results: Fifteen newborns were congenitally infected and 10 were uninfected as diagnosed on virus isolation from neonatal urine. Six of 15 infected newborns were positive for CMV antigenemia. CMV antigenemia had a positive predictive value of 100%, a negative predictive value of 52.6%, a sensitivity of 40%, and a specificity of 100%. CMV retinitis and pneumonitis were more prevalent among antigenemia-positive newborns (4/6) than antigenemia-negative newborns (0/9; P < 0.05). Conclusions: Antigenemia was significantly associated with retinitis and pneumonia, but it was not sensitive enough to diagnose intrauterine CMV infection. © 2008 Japan Pediatric Society.
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金子 政時
日本周産期・新生児医学会雑誌 = Journal of Japan Society of Perinatal and Neonatal Medicine 44 ( 4 ) 894 - 897 2008.12
Language：Japanese Publishing type：Research paper (scientific journal)