論文 - 榊原 陽一
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Concerted action of the cytosolic sulfotransferase, SULT1A3, and catechol-O-methyltransferase in the metabolism of dopamine in SK-N-MC human neuroblastoma cells
Shin Yasudaa, 1, Tomoko Yasudaa, Ying Huia, b, Ming-Yih Liuc, Masahito Suikod, Yoichi Sakakibarad and Ming-Cheh Liu
Neuroscience Research 64 ( 3 ) 273 - 279 2009年7月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Molecular Cloning, Expression, and Characterization of A Novel Mouse SULT6 Cytosolic Sulfotransferase 査読あり
Saki Takahashi, Yoichi Sakakibara, Emi Mishiro, Haruna Kouriki, Rika Nobe, Katsuhisa Kurogi, Shin Yasuda, Ming-Cheh Liu, Masahito Suiko
Journal of Biochemistry 2009年6月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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A target-specific approach for the identification of tyrosine-sulfated hemostatic protein 査読あり
Liu TA, Yasuda S, Williams FE, Liu MY, Suiko M, Sakakibara Y, Yang YS, Liu MC.
Anal Biochem. 2009年4月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Snapshot of a Michaelis complex in a sulfuryl transfer reaction: Crystal structure of a mouse sulfotransferase, mSULT1D1, complexed with donor substrate and accepter substrate. 査読あり
Teramoto T, Sakakibara Y, Liu MC, Suiko M, Kimura M, Kakuta Y.
Biochem Biophys Res Commun. 2009年4月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Structural basis for the broad range substrate specificity of a novel mouse cytosolic sulfotransferase--mSULT1D1. 査読あり
Teramoto T, Sakakibara Y, Liu MC, Suiko M, Kimura M, Kakuta Y.
Biochem Biophys Res Commun. 379 ( 1 ) 76 - 80 2009年1月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid. 査読あり
amasaki M, Kawabe A, Nishimoto K, Madhyastha H, Sakakibara Y, Suiko M, Okamoto T, Suda T, Uehira K, Nishiyama K.
n Vitro Cell Dev Biol Anim. 2009年1月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid 査読あり
Yamasaki M., Kawabe A., Nishimoto K., Madhyastha H., Sakakibara Y., Suiko M., Okamoto T., Suda T., Uehira K., Nishiyama K.
In Vitro Cellular and Developmental Biology - Animal 45 ( 5-6 ) 275 - 280 2009年
記述言語：英語 掲載種別：研究論文（学術雑誌） 出版者・発行元：In Vitro Cellular and Developmental Biology - Animal
Alpha-lipoic acid has been shown to possess cancer-cell-killing activity via activation of the apoptosis pathway. In this study, the cytotoxic activities of alpha-lipoic and dihydro-alpha-lipoic acid were compared in HL-60 cells. The cell-killing activity of dihydro-alpha-lipoic acid was higher than that of alpha-lipoic acid. Both alpha-lipoic and dihydro-alpha-lipoic acid induced caspase-3 cleavage and internucleosomal DNA fragmentation in treated cells. On the other hand, apparent necrotic or late-stage apoptotic cell populations could be detected in dihydro-alpha-lipoic acid cells but not in those treated with alpha-lipoic acid. Moreover, dihydro-alpha-lipoic acid, but not alpha-lipoic acid, induced marked mitochondrial permeability transition. Antioxidants could not prevent dihydro-alpha-lipoic- or alpha-lipoic-acidinduced cell death. In addition, dihydro-alpha-lipoic and alpha-lipoic acid did not up-regulate cellular reactive oxygen level. These results indicated that dihydro-alpha-lipoic acid exerts more potent cytotoxicity than alpha-lipoic acid through different cytotoxic actions. © The Society for In Vitro Biology 2008.
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Crystal sturucture of mSULT1D1, a mouse catecholamine sulfotransferase. 査読あり
Teramoto, T., Sakakibara, Y., Inaba, K., Kurogi, K., Liu, M.-C., Suiko, M., Kimura, M., Kakuta, Y.
FEBS Letter 582 3909 - 3914 2008年11月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Molecular cloning, expression, and characterization of mouse amine N-sulfotransferases. 査読あり
Takahashi S, Sakakibara Y, Mishiro E, Kouriki H, Nobe R, Kurogi K, Yasuda S, Liu MC, Suiko M.
Biochemical Biophysical Research Communication 375 ( 4 ) 531 - 535 2008年10月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Molecular cloning, expression, and characterization of mouse amine N-sulfotransferases 査読あり
Takahashi S., Takahashi S., Sakakibara Y., Sakakibara Y., Mishiro E., Mishiro E., Kouriki H., Nobe R., Nobe R., Kurogi K., Yasuda S., Yasuda S., Liu M., Suiko M., Suiko M.
Biochemical and Biophysical Research Communications 375 ( 4 ) 531 - 535 2008年10月
記述言語：英語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Biochemical and Biophysical Research Communications
By searching the GenBank database, we recently identified a novel mouse cytosolic sulfotransferase (SULT) cDNA (IMAGE Clone ID 679629) and a novel mouse SULT gene (LOC 215895). Sequence analysis revealed that both mouse SULTs belong to the cytosolic SULT3 gene family. The recombinant form of these two newly identified SULTs, designated SULT3A1 and SULT3A2, were expressed using the pGEX-4T-1 glutathione S-transferase fusion system and purified from transformed BL21 Escherichia coli cells. Both purified SULT3A1 and SULT3A2 exhibited strong amine N-sulfonating activities toward 1-naphthylamine among a variety of endogenous and xenobiotic compounds tested as substrates. Kinetic constants of the sulfation of 1-naphthylamine and 1-naphthol by these two enzymes were determined. Collectively, these results imply that these two amine-sulfonating SULT3s may play essential roles in the metabolism and detoxification of aromatic amine compounds in the body. © 2008 Elsevier Inc.
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Characterization and ontogenic study of novel steroid-sulfating SULT3 sulfotransferases from zebrafish 査読あり
Tomoko Yasuda, Shin Yasuda, Frederick E. Williams, Ming-Yih Liu, Yoichi Sakakibara, Shakhawat Bhuiyan, Rhodora Snow, Glendora Carter, Ming-Cheh Liu
Molecular Cellular Endocrinology 2008年7月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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抗変異原活性をもつ宮崎県産農産物の探索 査読あり
岩田喬子、榊原陽一、赤松絵奈、酒井美穂、柚木崎千鶴子、山崎正夫、西山和夫、水光正仁
宮崎大学農学部報 54 69 - 76 2007年12月
記述言語：日本語 掲載種別：研究論文（大学，研究機関等紀要）
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Soy-derived isoflavones inhibit the growth of adult T-cell leukemia cells in vitro and in vivo 査読あり
Yamasaki, M., Fujita, S., Ishiyama, E., Mukai, A., Madhyastha, H., Sakakibara, Y., Suiko, M., Hatakeyama, K., Nemoto, T., Morishita, K., Kataoka, H., Tsubouchi, H. and Nishiyama, K.
Cancer Science 98 ( 11 ) 1740 - 1746 2007年11月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Hydroxylated serotonin and dopamine as substrates and inhibitors for human cytosolic SULT1A3. 査読あり
Yasuda S., Liu M.Y., Suiko M., Sakakibara Y., Liu M.C.
Journal of Neurochemistry 103 ( 6 ) 2679 - 2689 2007年10月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Differential enzymatic characteristics and tissue-specific expression of human TPST-1 and TPST-2. 査読あり
Mishiro E, Sakakibara Y, Liu MC, Suiko M.
Journal of Biochemistry 140 ( 5 ) 731 - 737 2006年10月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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リポ酸によるヒト白血病細胞HL-60のアポトーシス誘導効果
山崎正夫、山根理学、西本健太郎、榊原陽一、水光正仁、西山和夫
FOOD FUNCTION 2 ( 1 ) 1 - 5 2006年1月
記述言語：日本語 掲載種別：研究論文（その他学術会議資料等）
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Identification of a novel thyroid hormone-sulfating cytosolic sulfotransferase, SULT1 ST5, from zebrafish
Yasuda, S., Kumar, A.P., Liu, M.-Y., Sakakibara, Y. その他３名
FEBS Journal 272 ( 15 ) 3828 - 3837 2005年8月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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本格焼酎の基本味を識別する脂質膜センサ
中原徳昭、榊原陽一、西山和夫、水光正仁 その他３名
日本食品科学工学会誌 52 ( 8 ) 355 - 365 2005年8月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Taste evaluation of Honkakushochu with taste sensor (research on the taste of Honkakushochu part I)
Nakahara N., Nakahara N., Sakaida H., Sakaida H., Kai T., Sakakibara Y., Nishiyama K., Fukuda N., Suiko M.
Nippon Shokuhin Kagaku Kogaku Kaishi 52 ( 4 ) 145 - 153 2005年7月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Nippon Shokuhin Kagaku Kogaku Kaishi
The possibility of use of taste sensors equipped with lipid/polymer membranes as one of the techniques which evaluate the taste of Honkakushochu was investigated. First, in order to determine chemical composition of a standard sample, the inorganic component of Honkakushochu was analyzed. The most abundant cation was sodium ion and the richest anion was chloride ion. These ions are considered to be brought in from the mother water used for dilution of Honkakushochu. Next, the measurement with sufficient reproducibility became possible by preparing the standard sample for the taste sensor suitable for evaluation of Honkakushochu. Measuring 41 kinds of Honkakushochu including rice, barley, sweet potato, buckwheat, brown sugar shochu and awamori using 8 taste sensors enabled to classify them based on their materials. Moreover, visual expression was able to be obtained about the taste patterns. Analyses of the data obtained from the taste sensor using the statistical techniques such as principal component analysis and cluster analysis suggested that the taste sensor could be useful for new product development or process control of Honkakushochu.
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味覚センサを用いた本格焼酎の味評価
中原徳昭、榊原陽一、西山和夫、水光正仁 その他３名
日本食品科学工学会誌 52 ( 4 ) 145 - 153 2005年4月
記述言語：英語 掲載種別：研究論文（学術雑誌）