論文 - 榊原 陽一
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Taste evaluation of Honkakushochu with taste sensor (research on the taste of Honkakushochu part I)
Nakahara N., Nakahara N., Sakaida H., Sakaida H., Kai T., Sakakibara Y., Nishiyama K., Fukuda N., Suiko M.
Nippon Shokuhin Kagaku Kogaku Kaishi 52 ( 4 ) 145 - 153 2005年7月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Nippon Shokuhin Kagaku Kogaku Kaishi
The possibility of use of taste sensors equipped with lipid/polymer membranes as one of the techniques which evaluate the taste of Honkakushochu was investigated. First, in order to determine chemical composition of a standard sample, the inorganic component of Honkakushochu was analyzed. The most abundant cation was sodium ion and the richest anion was chloride ion. These ions are considered to be brought in from the mother water used for dilution of Honkakushochu. Next, the measurement with sufficient reproducibility became possible by preparing the standard sample for the taste sensor suitable for evaluation of Honkakushochu. Measuring 41 kinds of Honkakushochu including rice, barley, sweet potato, buckwheat, brown sugar shochu and awamori using 8 taste sensors enabled to classify them based on their materials. Moreover, visual expression was able to be obtained about the taste patterns. Analyses of the data obtained from the taste sensor using the statistical techniques such as principal component analysis and cluster analysis suggested that the taste sensor could be useful for new product development or process control of Honkakushochu.
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味覚センサを用いた本格焼酎の味評価
中原徳昭、榊原陽一、西山和夫、水光正仁 その他３名
日本食品科学工学会誌 52 ( 4 ) 145 - 153 2005年4月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Biocides, tributyltin and triphenyltin, as possible inhibitors of the human sulfotransferase involved in the estrogen homeostasis
Ohkimoto, K., Sakakibara, Y., Suiko, M., Yoshikawa, H.その他２名
Pesticide Biochemistry and Physiology 81 132 - 138 2005年1月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Retronasal Aroma Simulatorを用いた穀類本格焼酎の含み香と立ち香分析
境田博至、榊原陽一、西山和夫、水光正仁 その他３名
日本食品科学工学会誌第52巻1号19-26頁 2005年1月
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Cloning and expression of a novel Trichoderma viride laminarinase AI gene (lamAI)
Nobe, R., Sakakibara, Y., Ogawa, K., Suiko, M.
Bioscience,Biotechnologyand Biochemistry 68 102111 - 102119 2004年10月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Zebrafish tyrosylprotein sulfotransferase: molecular cloning, expression,and functional characterization
Mishiro, E., Liu, M.-Y., Sakakibara, Y.Suiko, M., Liu, M.-C.
Biochemistry and Cell Biology 82 ( 2 ) 295 - 303 2004年4月
記述言語：英語 掲載種別：研究論文（学術雑誌）
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Characterization of a putative zebrafish estrogen sulfotransferase: inhibitory effects and mechanism of action of phytoestrogens
Ohkimoto, K., Liu, M.-Y., Suiko, M.Sakakibara, Y., Liu, M.-C.
Chemico-Biological InteractionsVol. 147, No. 1, 1-7 2004年1月
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蕎麦焼酎の特徴香及び穀類本格焼酎の揮発性成分分析について
境田博至、榊原陽一、西山和夫、水光正仁 その他５名
日本食品科学工学会誌第50巻12号555-562頁 2003年12月
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Sulfonation of environmental estrogens by zebrafish cytosolic sulfotransferases
Ohkimoto, K., Sugahara, T.,Sakakibara, Y., Suiko, M.その他３名
Biochemical and Biophysiccal ResearchCommunications Vol. 309, No. 17-11 2003年9月
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Purification and characterization of laminaran hydrolases from Trichoderma viride
Nobe, R., Sakakibara, Y., Fukuda, N.Yoshida, N., Ogawa, K., Suiko, M.
Bioscience,Biotechnologyand Biochemistry Vol. 67, No. 21349-1357 2003年6月
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Sulfation of hydroxychlorobiphenyls: Molecular cloning, expression, and functional characterization of zebrafish SULT1 sulfotransferases
Sugahara, T., Liu, C.-C., Suiko, M.Sakakibara, Y.その他４名
European Journal of BiochemistryVol. 270, No. 112404-2411 2003年6月
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Differential roles of human monoamine (M)-form and simplephenol (P)-form phenol sulfotransferases in drug metabolism
Sugahara, T., Pai, T.G., Suiko, M.Sakakibara, Y., Liu, M.-C.
Journal of BiochemistryVol. 133. No. 2259-262 2003年2月
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Structure-function relationships in the stereospecific and manganese-dependent dopa/tyrosine-sulfating activity of human monoamine-form phenol sulfotransferase, SULT1A3
Pai, T.G., Sugahara, T., Suiko, M.Sakakibara, Y.その他２名
The Journal ofBiological Chemistry Vol. 278, No.31525-1532 2003年1月
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Manganese stimulation and stereospecificity of the dopa (3,4-dihydroxyphenylalanine)/tyrosine-sulfating activity of human monoamine-form phenol sulfotransferase. kinetic studies of the mechanism using wild-type and mutant enzymes
Pai, T.G., Ohkimoto, K., Sakakibara, Y.Suiko, M.その他２名
The Journal ofBiological Chemistry Vol.277, No.4643813-43820 2002年11月
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Differential xenoestrogen-sulfating activities of the human cytosolic sulfotransferases: molecular cloning, expression, and purification of human SULT2B1a and SULT2B1b sulfotransferases
Pai, T.G., Sugahara, T., Suiko, M.Sakakibara, Y.その他２名
BiochimicaBiophysicaActaVol. 1573, No. 2165-170 2002年11月
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Regulatory effects of divalent metal cations on human cytosolic sulfotransferases
Xu, F., Suiko, M., Sakakibara, Y.Pai, T.G., Liu, M.-C.
Journal of BiochemistryVol.132, No.3457-462 2002年9月
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Highly conserved mouse and human brain sulfotransferases: molecular cloning, expression, and functional characterization
Sakakibara, Y., Suiko, M., Pai, T.G.Nakayama, T.その他３名
GeneVol. 285, No. 1-239-47 2002年2月
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Sulfation of flavonoids and other phenolic dietary compounds by the human cytosolic sulfotransferases
Pai, T.G., Suiko, M., Sakakibara, Y.Liu, M.-C
Biochemical and Biophysiccal ResearchCommunications Vol. 285, No. 31175-1179 2001年8月
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Ranasinghe J., Liu M., Sakakibara Y., Sakakibara Y., Takeshita Y., Fukuda N., Nasu T., Suiko M.
Journal of Molecular Catalysis - B Enzymatic 12 ( 1-6 ) 131 - 136 2001年2月
記述言語：英語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Journal of Molecular Catalysis - B Enzymatic
In our previous studies, we have demonstrated the stereoselective and manganese-dependent sulfation of tyrosine and Dopa isomers by human monoamine (M)-form phenol sulfotransferase (PST). In the present study, we investigated the occurrence of these phenomena in vivo using Sprague-Dawley rats as an experimental model. Three groups of six male rats were orally introduced with 1ml of, respectively, 3mM, 10mM and 30mM MnCl2 with a constant level of 0.2mM DL-m-tyrosine per day for 7 days. Their urine was collected and analyzed for the presence of sulfated DL-m-tyrosine (DL-m-TyrS) by ion-pair HPLC using a C18 reversed-phase column. The level of urinary DL-m-TyrS, which was detected in the urine of the MnCl2-treated rats but not control rats, appeared to increase proportionally to the amount of MnCl2 administered. Chiral HPLC was employed to differentiate the D-form and L-form m-TyrS present in the urine sample of MnCl2-treated rats. Both D-m-TyrS and L-m-TyrS were detected, with the D-form being present at significantly higher level than the L-form. Copyright © 2001 Elsevier Science B.V.
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Stereoselective and manganese-dependent sulfation and urinary excretion of D-form and L-form meta-tyrosine O-sulfate by Sprague-Dawly rats
Ranasinghe, J.G.S., Liu, M.-C.Sakakibara, Y., Takeshita, Y.その他３名
Journal of Molecular Catalysis B:EnzymaticVol. 12, 131-136 2001年2月