論文 - 榊原 陽一
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Biocides, tributyltin and triphenyltin, as possible inhibitors of the human sulfotransferase involved in the estrogen homeostasis
Ohkimoto, K., Sakakibara, Y., Suiko, M., Yoshikawa, H.その他2名
Pesticide Biochemistry and Physiology 81 132 - 138 2005年1月
記述言語:英語 掲載種別:研究論文(学術雑誌)
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Retronasal Aroma Simulatorを用いた穀類本格焼酎の含み香と立ち香分析
境田博至、榊原陽一、西山和夫、水光正仁 その他3名
日本食品科学工学会誌第52巻1号19-26頁 2005年1月
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Cloning and expression of a novel Trichoderma viride laminarinase AI gene (lamAI)
Nobe, R., Sakakibara, Y., Ogawa, K., Suiko, M.
Bioscience,Biotechnologyand Biochemistry 68 102111 - 102119 2004年10月
記述言語:英語 掲載種別:研究論文(学術雑誌)
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Zebrafish tyrosylprotein sulfotransferase: molecular cloning, expression,and functional characterization
Mishiro, E., Liu, M.-Y., Sakakibara, Y.Suiko, M., Liu, M.-C.
Biochemistry and Cell Biology 82 ( 2 ) 295 - 303 2004年4月
記述言語:英語 掲載種別:研究論文(学術雑誌)
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Characterization of a putative zebrafish estrogen sulfotransferase: inhibitory effects and mechanism of action of phytoestrogens
Ohkimoto, K., Liu, M.-Y., Suiko, M.Sakakibara, Y., Liu, M.-C.
Chemico-Biological InteractionsVol. 147, No. 1, 1-7 2004年1月
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蕎麦焼酎の特徴香及び穀類本格焼酎の揮発性成分分析について
境田博至、榊原陽一、西山和夫、水光正仁 その他5名
日本食品科学工学会誌第50巻12号555-562頁 2003年12月
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Sulfonation of environmental estrogens by zebrafish cytosolic sulfotransferases
Ohkimoto, K., Sugahara, T.,Sakakibara, Y., Suiko, M.その他3名
Biochemical and Biophysiccal ResearchCommunications Vol. 309, No. 17-11 2003年9月
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Purification and characterization of laminaran hydrolases from Trichoderma viride
Nobe, R., Sakakibara, Y., Fukuda, N.Yoshida, N., Ogawa, K., Suiko, M.
Bioscience,Biotechnologyand Biochemistry Vol. 67, No. 21349-1357 2003年6月
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Sulfation of hydroxychlorobiphenyls: Molecular cloning, expression, and functional characterization of zebrafish SULT1 sulfotransferases
Sugahara, T., Liu, C.-C., Suiko, M.Sakakibara, Y.その他4名
European Journal of BiochemistryVol. 270, No. 112404-2411 2003年6月
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Differential roles of human monoamine (M)-form and simplephenol (P)-form phenol sulfotransferases in drug metabolism
Sugahara, T., Pai, T.G., Suiko, M.Sakakibara, Y., Liu, M.-C.
Journal of BiochemistryVol. 133. No. 2259-262 2003年2月
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Structure-function relationships in the stereospecific and manganese-dependent dopa/tyrosine-sulfating activity of human monoamine-form phenol sulfotransferase, SULT1A3
Pai, T.G., Sugahara, T., Suiko, M.Sakakibara, Y.その他2名
The Journal ofBiological Chemistry Vol. 278, No.31525-1532 2003年1月
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Manganese stimulation and stereospecificity of the dopa (3,4-dihydroxyphenylalanine)/tyrosine-sulfating activity of human monoamine-form phenol sulfotransferase. kinetic studies of the mechanism using wild-type and mutant enzymes
Pai, T.G., Ohkimoto, K., Sakakibara, Y.Suiko, M.その他2名
The Journal ofBiological Chemistry Vol.277, No.4643813-43820 2002年11月
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Differential xenoestrogen-sulfating activities of the human cytosolic sulfotransferases: molecular cloning, expression, and purification of human SULT2B1a and SULT2B1b sulfotransferases
Pai, T.G., Sugahara, T., Suiko, M.Sakakibara, Y.その他2名
BiochimicaBiophysicaActaVol. 1573, No. 2165-170 2002年11月
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Regulatory effects of divalent metal cations on human cytosolic sulfotransferases
Xu, F., Suiko, M., Sakakibara, Y.Pai, T.G., Liu, M.-C.
Journal of BiochemistryVol.132, No.3457-462 2002年9月
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Highly conserved mouse and human brain sulfotransferases: molecular cloning, expression, and functional characterization
Sakakibara, Y., Suiko, M., Pai, T.G.Nakayama, T.その他3名
GeneVol. 285, No. 1-239-47 2002年2月
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Sulfation of flavonoids and other phenolic dietary compounds by the human cytosolic sulfotransferases
Pai, T.G., Suiko, M., Sakakibara, Y.Liu, M.-C
Biochemical and Biophysiccal ResearchCommunications Vol. 285, No. 31175-1179 2001年8月
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Ranasinghe J., Liu M., Sakakibara Y., Sakakibara Y., Takeshita Y., Fukuda N., Nasu T., Suiko M.
Journal of Molecular Catalysis - B Enzymatic 12 ( 1-6 ) 131 - 136 2001年2月
記述言語:英語 掲載種別:研究論文(学術雑誌) 出版者・発行元:Journal of Molecular Catalysis - B Enzymatic
In our previous studies, we have demonstrated the stereoselective and manganese-dependent sulfation of tyrosine and Dopa isomers by human monoamine (M)-form phenol sulfotransferase (PST). In the present study, we investigated the occurrence of these phenomena in vivo using Sprague-Dawley rats as an experimental model. Three groups of six male rats were orally introduced with 1ml of, respectively, 3mM, 10mM and 30mM MnCl2 with a constant level of 0.2mM DL-m-tyrosine per day for 7 days. Their urine was collected and analyzed for the presence of sulfated DL-m-tyrosine (DL-m-TyrS) by ion-pair HPLC using a C18 reversed-phase column. The level of urinary DL-m-TyrS, which was detected in the urine of the MnCl2-treated rats but not control rats, appeared to increase proportionally to the amount of MnCl2 administered. Chiral HPLC was employed to differentiate the D-form and L-form m-TyrS present in the urine sample of MnCl2-treated rats. Both D-m-TyrS and L-m-TyrS were detected, with the D-form being present at significantly higher level than the L-form. Copyright © 2001 Elsevier Science B.V.
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Stereoselective and manganese-dependent sulfation and urinary excretion of D-form and L-form meta-tyrosine O-sulfate by Sprague-Dawly rats
Ranasinghe, J.G.S., Liu, M.-C.Sakakibara, Y., Takeshita, Y.その他3名
Journal of Molecular Catalysis B:EnzymaticVol. 12, 131-136 2001年2月
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Manganese administration induces the increased production of dopamine sulfate and depletion of dopamine in Sprague-Dawley rats
Ranasinghe, J.G.S., Liu, M.-C.Sakakibara, Y., Suiko, M.
Journal of BiochemistryVol. 128, No. 3477-480 2000年9月
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Mutational analysis of the substrate-binding/catalytic domains of human M-form and P-form phenol sulfotransferases
Liu, M.-C., Suiko, M., Sakakibara, Y.
The Journal ofBiological ChemistryVol. 275, No. 1813460-13464 2000年5月