Papers - AYABE Takanori
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Tomita M., Ayabe T., Chosa E., Nose N., Nakamura K.
General Thoracic and Cardiovascular Surgery 64 ( 11 ) 657 - 661 2016.11
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：General Thoracic and Cardiovascular Surgery
© 2016, The Japanese Association for Thoracic Surgery. Objectives: We retrospectively analyzed the prognostic significance of preoperative serum Krebs von den Lungen-6 (KL-6) level in non-small cell lung cancer (NSCLC) patients. Methods: We enrolled 175 NSCLC patients who underwent curative surgery between 2009 and 2011. We subdivided the patients into 2 groups: with and without interstitial lung disease (ILD). Prognostic significance of serum KL-6 level was examined. Results: The 5-year survival of patients with high serum KL-6 level was poor. Multivariate analysis also revealed the prognostic significance of serum KL-6 level. Serum KL-6 level was also a prognostic factor for patients without ILD. Although the number of patients with ILD was small, in patients with ILD, there was a trend towards an association between serum KL-6 level and patients’ prognosis but this did not reach statistical significance. Conclusions: Serum KL-6 level is a prognostic factor for resected NSCLC patients, especially patients without ILD. There is a possibility that serum KL-6 level is a prognostic marker regardless of the presence of ILD.
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外科医師が報告したインシデントレポート Reviewed
綾部貴典、富田雅樹、帖佐英一、中村都英
宮崎県医師会雑誌 - 5 2016.10
Language：Japanese Publishing type：Research paper (scientific journal)
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Port-site implantation of Type A Masaoka Stage I thymoma after video-assisted thoracic surgery: a case report.
Nose N, Higuchi K, Chosa E, Ayabe T, Tomita M, Nakamura K
Journal of surgical case reports 2016 ( 9 ) 2016.9
Language：Japanese Publishing type：Research paper (scientific journal)
DOI： 10.1093/jscr/rjw164
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Severity of Chronic Obstructive Pulmonary Disease and the Prognosis of Non-Small Cell Lung Cancer Patients Reviewed
Tomita, M., Ayabe, T., Chosa, E., Nose, N., Tsuchiya, K., Nakamura, K.
Advances in Lung Cancer 5 13 - 20 2016.9
Language：English Publishing type：Research paper (scientific journal)
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Port-site implantation of Type A Masaoka Stage I thymoma after video-assisted thoracic surgery: a case report. Reviewed
Nose, N., Higuchi, K., Chosa, E., Ayabe, T., Tomita, M., and Nakamura,
Journal of Surgical Case Reports 9 1 - 3 2016.9
Language：English Publishing type：Research paper (scientific journal)
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二期的に手術を行った両側巨大肺嚢胞症の1例 Reviewed
綾部貴典、富田雅樹、中村都英
日気嚢疾会誌 15 1 - 5 2016.9
Language：Japanese Publishing type：Research paper (scientific journal)
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Prognostic significance of preoperative serum Krebs von den Lungen-6 level in non-small cell lung cancer. Reviewed
Tomita, M., Ayabe, T., Chosa, E., Nose,N., Nakamura, K.
Gen Thorac Cardiovasc Surg 64 657 - 661 2016.8
Language：English Publishing type：Research paper (scientific journal)
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Unexpected Intraoperative Resecting of Common Trunk of Pulmonary Vein Resulted in an Incidental Pneumonectomy from Left Upper Lobectomy Reviewed
Ayabe, T., Tomita, M, Nose, N, Chosa, E, Higuchi, K., Nakamura, K.
Open Journal of Thoracic Surgery 6 18 - 24 2016.8
Language：English Publishing type：Research paper (scientific journal)
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妊娠を契機に増大したと推測される長径16cm胸壁デスモイド腫瘍の1例 Reviewed
帖佐英一、綾部貴典、森 浩貴、富田雅樹、中村都英
日本臨床外科学会雑誌 77 41 - 47 2016.6
Language：Japanese Publishing type：Research paper (scientific journal)
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ポータブル型胸腔ドレナージ装置トパーズの臨床的有用性の検討 Reviewed
富田雅樹, 綾部貴典, 帖佐英一, 能勢直弘, 中村都英
宮崎医会誌 40 140 - 146 2016.5
Language：Japanese Publishing type：Research paper (scientific journal)
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巨大肺嚢胞の2切除例 Reviewed
綾部貴典、富田雅樹、帖佐英一、川越勝也、中村都英
宮崎医会誌 40 41 - 46 2016.4
Language：Japanese Publishing type：Research paper (scientific journal)
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Clinical Outcomes, Safety and Efficacy of Intrapleural Hyperthermic Chemotherapy for Thoracic Malignant Diseases with Pleural Effusion Reviewed
Ayabe, T., Tomita, M., Chosa, E., Mori, H. and Nakamura, K.
Journal of Cancer Therapy 7 203 - 215 2016.4
Language：English Publishing type：Research paper (scientific journal)
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Outcomes of Quality of Life Regarding the Next-Generation Thoracoscopic Intrapleural Hyperthermic Chemotherapy of Non-Small Cell Lung Cancer with Dissemination Reviewed
Ayabe, T., Tomita, M., Chosa, E., Mori, K. and Nakamura, K.
Journal of Cancer Therapy 7 203 - 215 2016.3
Language：English Publishing type：Research paper (scientific journal)
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CHOSA Eiichi, AYABE Takanori, MORI Hiroki, TOMITA Masaki, NAKAMURA Kunihide
Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 77 ( 3 ) 545 - 551 2016
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Japan Surgical Association
A 29-year-old pregnant woman was admitted to the hospital because of dyspnea and left chest pain. We preferentially considered the maternal safety and performed artificial abortion. Chest computed tomographic (CT) scan and magnetic resonance imaging (MRI) revealed a 15×8×16cm tumor on the left anterior chest wall, which had compressed the heart. The pathological diagnosis of ultrasonography- guided biopsy specimen was desmoid tumor. Tumor resection was done. The left chest wall including the 7th to the 10th ribs was resected with the pericardium and diaphragm. A wide defect of the chest wall was reconstructed with mesh. However, the patient developed wound infection, and the infected mesh had to be removed. The defect of the chest wall was reconstructed with a free tensor fascia lata musculocutaneous flap. No evidence of recurrence has been found for 6 years after the resection. Desmoid tumors during pregnancy are rare and the courses of treatment are controversial. Further accumulation of cases is necessary.
DOI： 10.3919/jjsa.77.545
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妊娠中に胸腔鏡下肺切除術を施行した自然気胸の2例 Reviewed
米井 彰洋，市成 秀樹、峯 一彦、綾部 貴典、富田 雅樹、中村 都英
日呼外会誌 ２９ ８７５ - ８７９ 2015.11
Language：Japanese Publishing type：Research paper (scientific journal)
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Postoperative Serum CEA Level is a More Significant Prognostic Factor than Post/Preoperative Serum CEA Ratio in Non-small Cell Cancer Patients. Reviewed
Masaki Tomita, Takanori Ayabe, Eiichi Chosa, Kunihide Nakamura,
Asian Pacific Journal of Cancer Prevention 16 7809 - 7812 2015.10
Language：English Publishing type：Research paper (scientific journal)
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Yorita K., Ayabe T., Chosa E., Uchino N., Nagatomo Y., Yamaguchi T., Nakatani Y., Kataoka H.
Pathology International 65 ( 10 ) 558 - 562 2015.10
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Pathology International
© 2015 Japanese Society of Pathology and Wiley Publishing Asia Pty Ltd. Pulmonary hamartoma is a common benign lung disorder, and most cases show solid nodules. Here, we documented the clinicopathological features of a growing, bulla-like, multilocular hamartomatous lung lesion in a woman of reproductive age. To the best of our knowledge, this disorder has not been reported in the literature to date. An asymptomatic 29-year-old Japanese woman with no significant past medical history was referred to our institution for surgical treatment of a bullous lesion in the right upper lobe because the pulmonary lesion had enlarged to multilocular cysts, including a giant bulla, within 1 year, leading to compression of the right lung. The bullous lesion, which was projected from the apex of the lung via a narrow stalk, showed nonemphysematous, multiloculated tissue. The wall mimicked a bronchiolar structure with ciliated, nonatypical epithelium and layers of nonatypical spindle cells that were positive for smooth muscle markers and sex steroid hormone receptors. No cartilage was included in the lesion. We believe that this may be a novel form of hamartoma. This disorder may be included in a differential diagnosis of subpleural bullous diseases in women of reproductive age.
DOI： 10.1111/pin.12342
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Impact of smoking on outcome of resected lung adenocarcinoma. Reviewed
Masaki Tomita, Takanori Ayabe, Eiichi Chosa, Kunihide Nakamura
Gen Thorac Cardiovasc Surg ６３ ６０８ - ６１２ 2015.9
Language：English Publishing type：Research paper (scientific journal)
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Unusual cystic hamartomatous lung lesion with clinical manifestation of subpleural bullae in a woman of reproductive age: A case report. Reviewed
Kenji Yorita, Takanori Ayabe, Eiichi Chosa, Noriko Uchino, Yasuhiro Nagatomo, Tetsuro Yamaguchi, Yukio Nakatani, and Hiroaki Kataoka,
Pathology International 65 558 - 562 2015.8
Language：English Publishing type：Research paper (scientific journal)
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Impact of smoking on outcome of resected lung adenocarcinoma
Tomita M., Ayabe T., Chosa E., Nakamura K.
General Thoracic and Cardiovascular Surgery 63 ( 11 ) 608 - 612 2015.8
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：General Thoracic and Cardiovascular Surgery
© 2015, The Japanese Association for Thoracic Surgery. Objective: Smoking is a well-known causative factor of lung cancer and the association of smoking with adenocarcinoma is considered to be the weakest. We investigated the influence of smoking on postoperative prognosis in patients with lung adenocarcinoma. Methods: One hundred and eighty-one consecutive patients of resected lung adenocarcinoma were studied retrospectively. The histologic subtype was subdivided into 2 groups: lepidic dominant histologic subtype, including adenocarcinoma in situ, minimally invasive adenocarcinoma, and lepidic predominant invasive adenocarcinoma versus other subtypes. Results: The 5-year survival of ever smokers was significantly unfavorable than that of never smokers. Similarly, there was also a relationship between the patients’ survival and Brinkman index (BI), with unfavorable survival found in patients with greater smoking histories. Based on a multivariable analysis, pN status and BI were significant factors affecting the postoperative prognosis of patients undergoing surgery. However, gender, serum carcinoembryonic antigen (CEA) level, lepidic dominant histologic subtype and pure/mixed ground-glass opacity (GGO) were not prognostic factors although previous reports showed prognostic significance. These factors that we failed to find the prognostic significance were significantly associated with smoking. Conclusion: The smoking was significantly predictive of an unfavorable prognosis after surgery for lung adenocarcinoma. It is suggested that smoking is associated with serum CEA level, histologic subtype and GGO, resulting in unfavorable outcome.