Papers - AYABE Takanori
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Case Reports in Surgery 2011 4 pages 2011.7
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1155/2011/902062
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根治的化学放射線療法後の遺残・再発食道癌に対する救済手術（Salvage手術）の長期成績 Reviewed
綾部貴典、松崎泰憲、清水哲哉、原政樹、富田雅樹、 鬼塚敏男
宮崎県医師会雑誌 35 100 - 107 2011.7
Language：Japanese Publishing type：Research paper (scientific journal)
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Bronchoscopic Removal of Staple-Line Reinforcement Material Reviewed
Journal of Bronchology & Interventional Pulmonology 18 ( 3 ) 274 - 277 2011.7
Language：English Publishing type：Research paper (scientific journal)
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Bronchial Flap Closure of the Lower Membranous Trachea Reviewed
Tomita M, Shimizu T, Ayabe T, Yonei A, and Onitsuka T
Ann Thorac Surg 91 935 - 937 2011.5
Language：English Publishing type：Research paper (scientific journal)
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Preoperative Neutrophil to Lymphocyte Ratio as a Prognostic Predictor after Curative Resection for Non-small Cell Lung Cancer Reviewed
MASAKI TOMITA, TETSUYA SHIMIZU, TAKANORI AYABE, AKIHIRO YONEI, and TOSHIO ONITSUKA
ANTICANCER RESEARCH 31 2995 - 2998 2011.5
Language：English Publishing type：Research paper (scientific journal)
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アンスラサイクリン系抗癌剤の術前化学療法による薬剤性心筋症合併乳癌の１切除例 Reviewed
綾部貴典、富田雅樹、原政樹、清水哲哉、松崎泰憲、鬼塚敏男
宮崎県医師会雑誌 35 108 - 115 2011.5
Language：Japanese Publishing type：Research paper (scientific journal)
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Bronchial flap closure of the lower membranous trachea
Tomita M., Shimizu T., Ayabe T., Yonei A., Onitsuka T.
Annals of Thoracic Surgery 91 ( 3 ) 935 - 937 2011.3
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Annals of Thoracic Surgery
A novel method for closure of the lower membranous trachea after right pneumonectomy using a flap derived from the cartilaginous portion of the right main bronchus is described in this study. This technique was used successfully in patients with tracheal stenosis due to a giant posterior mediastinal tumor known as schwannoma. Because of the severe tracheobronchial stenosis and destroyed right lung, tumor resection combined with resection of the lower membranous trachea and right pneumonectomy was carried out. We closed the defect in the membranous lower trachea with the flap derived from the right main bronchus. The clinical course was uneventful. © 2011 The Society of Thoracic Surgeons.
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TOMITA Masaki, SHIMIZU Tetsuya, AYABE Takanori, ONITSUKA Toshio
General thoracic and cardiovascular surgery 58 ( 11 ) 573 - 576 2010.11
Language：Japanese Publishing type：Research paper (scientific journal)
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Tomita M., Shimizu T., Ayabe T., Onitsuka T.
General Thoracic and Cardiovascular Surgery 58 ( 11 ) 573 - 576 2010.11
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：General Thoracic and Cardiovascular Surgery
Purpose: The prognostic significance of the combined use of preoperative platelet count and serum carcinoembryonic antigen (CEA) level in non-small-cell lung cancer patients was investigated. Methods: Consecutive 289 non-small-cell lung cancer patients were reviewed retrospectively. Thrombocytosis was defined as a platelet count of at least 40 × 104/mm3. Results: The frequency of preoperative thrombocytosis was 4.5% (13/289). The 5-year survival of patients with thrombocytosis was 30.77%, which was significantly poorer than that of patients with normal counts (68.65%, P = 0.0010). The 5-year survivals of patients with a normal CEA level and those with an elevated serum CEA level were 74.18% and 55.78%, respectively (P = 0.0019). Patients with both a normal platelet count and a normal serum CEA level had a favorable prognosis, whereas those with both thrombocytosis and elevated serum CEA level had a poor prognosis. The prognostic impact of the combined use of the platelet count and the serum CEA level was more significant than that of the platelet count or the serum CEA level alone. Both univariate and multivariate analyses indicated an independent prognostic impact of the combined use of platelet count and serum CEA levels. Conclusion: The combined use of preoperative platelet count and serum CEA levels might be useful for predicting the prognosis of non-small-cell lung cancer patients. © 2010 The Japanese Association for Thoracic Surgery.
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Carcinoembryonic antigen level in serum and pleural lavage fluid in non-small cell lung cancer
Tomita M., Shimizu T., Ayabe T., Yonei A., Onitsuka T.
Thoracic and Cardiovascular Surgeon 58 ( 6 ) 350 - 353 2010.9
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Thoracic and Cardiovascular Surgeon
Background: This study evaluates the tumor marker index (TMI) based on carcinoembryonic antigen (CEA) levels in serum and pleural lavage fluid as a potential prognostic determinant for patients with non-small cell lung cancer (NSCLC). Materials and Methods: Three hundred and eighty-three consecutive NSCLC patients were reviewed retrospectively. Results: The 5-year survival of patients with normal and high serum CEA levels was 71.78% and 51.38%, respectively (p<0.0001). The 5-year survival of patients with high CEA levels in pleural lavage fluid was 25.0%, which was significantly poorer compared with that of patients with normal lavage CEA levels (78.23%, p<0.0001). There was a 5-year survival rate of 73.75% in patients with a TMI less than or equal to 1.0 compared to a rate of only 55.12% in patients with a TMI greater than 1.0 (p<0.001). Both univariate and multivariate analyses indicated the independent prognostic impact of the TMI. Conclusions: The TMI based on serum and lavage CEA levels might be useful for predicting the prognosis of NSCLC patients. © Georg Thieme Verlag KG Stuttgart - New York.
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Tomita M., Shimizu T., Ayabe T., Yonei A., Onitsuka T.
Anticancer Research 30 ( 7 ) 3099 - 3102 2010.7
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Anticancer Research
Background: Prognostic impact of tumour marker index (TMI) based on preoperative serum carcinoembryonic antigen (CEA) and CYFRA 21-1 in non-small cell lung cancer (NSCLC) was examined using patients with a follow-up period more than 5 years. Patients and Methods: Two hundred and ninety-three consecutive NSCLC patients were reviewed retrospectively, and any patients with follow-up periods less than 5 years were omitted. Results: The 5-year survival of the patients with normal and high serum CEA levels was 7152% and 48.41%, respectively (p<0.0001). The 5-year survival of the patients with a high serum CYFRA 21-1 level was 39.66%, which was significantly poorer compared with that of the patients with a normal serum CYFRA 21-1 level (66.95%, p<0.0001). There was a 5-year-survival rate of 72.28% in patients with a TMI less than or equal to 1.0 compared to only 37.08% in patients with a TMI greater than 1.0 (p<0.0001). Both univariate and multivariate analyses indicated the independent prognostic impact of TMI. Conclusions: TMI may be useful for predicting the prognosis of NSCLC patients.
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Prognostic significance of tumour marker index based on preoperative CEA and CYFRA 21-1 in non-small cell lung cancer.
Tomita M, Shimizu T, Ayabe T, Yonei A, Onitsuka T
Anticancer research 30 ( 7 ) 3099 - 102 2010.7
Language：Japanese Publishing type：Research paper (scientific journal)
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Postoperative Serum C-Reactive Protein Levels in Non-Small Cell Lung Cancer Patients
HARA Masaki, YONEI Akihiro, AYABE Takanori, TOMITA Masaki, NAKAMURA Kunihide, ONITSUKA Toshio
Annals of thoracic and cardiovascular surgery 16 ( 2 ) 85 - 90 2010.4
Language：Japanese Publishing type：Research paper (scientific journal)
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Prognostic significance of the combined use of preoperative platelet count and serum carcinoembryonic antigen level in non-small-cell cancer Reviewed
Tomita M, Shimizu T, Ayabe T, and Onitsuka T
Gen Thorac Cardiovasc Surg 58 573 - 576 2010.4
Language：English Publishing type：Research paper (scientific journal)
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Carcinoembryonic Antigen Level in Serum and Pleural Lavage Fluid in Non-Small Lung Cancer Reviewed
Tomita M, Shimizu T, Ayabe T, Yonei T, and Onitsuka T
Thorac Cardiovasc Surg 58 350 - 353 2010.4
Language：English Publishing type：Research paper (scientific journal)
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"Postoperative Serum C-Reactive Protein Level in Non-Small Cell Lung Cancer Patients Reviewed
Hara M, Yonei A, Ayabe T, Tomita M, Nakamura K, and Onitsuka T
Ann Thorac Cardiovasc Surg 16 85 - 90 2010.4
Language：English Publishing type：Research paper (scientific journal)
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Prognostic Significance of Tumour Marker Index Based on Preoperative CEA and CYFRA 21-1 in Non-small Cell Lung Cancer Reviewed
Tomita M, Shimizu T, Ayabe T, Yonei A, and Onitsuka T
Anticancer Research 30 3099 - 3102 2010.4
Language：English Publishing type：Research paper (scientific journal)
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Postoperative serum C-reactive protein levels in non-small cell lung cancer patients
Hara M., Yonei A., Ayabe T., Tomita M., Nakamura K., Onitsuka T.
Annals of Thoracic and Cardiovascular Surgery 16 ( 2 ) 85 - 90 2010.4
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Annals of Thoracic and Cardiovascular Surgery
Purpose: The significance of the postoperative serum C-reactive protein (CRP) level as a prognosis indicator was evaluated in patients with non-small cell lung cancer (NSCLC). Patients and Methods: A total of 276 patients who had undergone a curative resection of NSCLC were retrospectively reviewed.&Results: The overall and disease-specific survival rates in the postoperative CRP/high group (≥ 0.5 mg/dL at 30 days postoperation: n = 130) were significantly lower than those in the postoperative CRP/low group (< 0.5 mg/dL at 30 days postoperation: n = 146). However, based on a multivariate analysis, the postoperative CRP level was not among the unfavorable indicators regarding survival. The patients were divided into two groups, namely, the preop-erative CRP/low group (n = 231) and the CRP/high group (n = 45). The proportion of the postoperative CRP/low group (60.2%) in the preoperative CRP/low group was significantly lower than that in the preoperative CRP/low group (15.6%; p <0.0001). No significant difference was observed in the disease-specific survival rates in the postoperative CRP/high group and the postoperative CRP/low group in either the preoperative high/group or low/group. Conclusions: The overall and disease-specific survival rates in the postoperative CRP/high group were significantly lower than that in the postoperative CRP/low group. This difference may be associated with the relationship between the pre- and postoperative CRP levels.
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Postoperative serum C-reactive protein levels in non-small cell lung cancer patients.
Hara M, Yonei A, Ayabe T, Tomita M, Nakamura K, Onitsuka T
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia 16 ( 2 ) 85 - 90 2010.4
Language：Japanese Publishing type：Research paper (scientific journal)
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Tomita M., Shimizu T., Hara M., Ayabe T., Onitsuka T.
Anticancer Research 29 ( 7 ) 2687 - 2690 2009.7
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Anticancer Research
Background: Previous studies have reported any prognostic impact of preoperative leukocytosis, anemia and thrombocytosis in non-small cell lung cancer (NSCLC). The significance of the combined use of these 3 abnormal blood cell counts was investigated. Patients and Methods: Two hundred and eighty-nine consecutive NSCLC patients were reviewed retrospectively. Results: The patients with leukocytosis, anemia and thrombocytosis had significantly worse prognosis. The 5-year survival of the patients with all three of these abnormal blood cell counts was 25.0%, which was significantly poorer compared with that of the patients without any of these abnormal cell counts (78.23%). The 5-year survival of the patients with 1 or 2 out of the three abnormal blood cell counts was an intermediate value. Both univariate and multivariate analyses indicated the independent prognostic impact of the use of these three abnormal blood cell counts combined. Conclusion: The use of leukocytosis, anemia and thrombocytosis combined might be useful for predicting the prognosis of NSCLC patients.