Papers - NANASHIMA Atsushi
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Short-term outcomes of laparoscopic surgery for colorectal cancer in oldest-old patients.
Tominaga T, Takeshita H, Arai J, Takagi K, Kunizaki M, To K, Abo T, Hidaka S, Nanashima A, Nagayasu T, Sawai T
Digestive surgery 32 ( 1 ) 32 - 8 2015
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Prediction of portal pressure from intraoperative ultrasonography.
Nanashima A, Abo T, Arai J, Tominaga T, Takagi K, Mochinaga K, Furukawa K, Nagayasu T
The Journal of surgical research 192 ( 2 ) 395 - 401 2014.12
Language：Japanese Publishing type：Research paper (scientific journal)
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Usefulness of evaluating hepatic elasticity using artificial acoustic radiation force ultrasonography before hepatectomy.
Nanashima A, Sakamoto A, Sakamoto I, Hayashi H, Abo T, Wakata K, Murakami G, Arai J, Wada H, Takagi K, Takeshita H, Hidaka S, To K, Nagayasu T
Hepatology research : the official journal of the Japan Society of Hepatology 44 ( 13 ) 1308 - 19 2014.12
Language：Japanese Publishing type：Research paper (scientific journal)
DOI： 10.1111/hepr.12306
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Three-dimensional printing model of liver for operative simulation in perihilar cholangiocarcinoma.
Takagi K, Nanashima A, Abo T, Arai J, Matsuo N, Fukuda T, Nagayasu T
Hepato-gastroenterology 61 ( 136 ) 2315 - 6 2014.11
Language：Japanese Publishing type：Research paper (scientific journal)
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Video-assisted thoracoscopic lobectomy with the patient in the semi-prone position: initial experience and benefits of lymph node dissection.
Miyazaki T, Nagayasu T, Yamasaki N, Tsuchiya T, Matsumoto K, Tagawa T, Obatake M, Nanashima A, Hidaka S, Hayashi T
General thoracic and cardiovascular surgery 62 ( 10 ) 614 - 9 2014.10
Language：Japanese Publishing type：Research paper (scientific journal)
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The poly(adenosine diphosphate-ribose) polymerase inhibitor PJ34 reduces pulmonary ischemia-reperfusion injury in rats.
Hatachi G, Tsuchiya T, Miyazaki T, Matsumoto K, Yamasaki N, Okita N, Nanashima A, Higami Y, Nagayasu T
Transplantation 98 ( 6 ) 618 - 24 2014.9
Language：Japanese Publishing type：Research paper (scientific journal)
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Clinical significance of vessel-sealing device usage for pancreatectomy: a retrospective cohort study.
Nanashima A, Abo T, Takagi K, Wada H, Arai J, Kunizaki M, To K, Takeshita H, Hidaka S, Nagayasu T
Hepato-gastroenterology 61 ( 134 ) 1767 - 74 2014.9
Language：Japanese Publishing type：Research paper (scientific journal)
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Clinicopathological parameters associated with surgical site infections in patients who underwent pancreatic resection. Reviewed
Nanashima A, Abo T, Arai J, Oyama S, Mochinaga K, Matsumoto H, Takagi K, Kunizaki M, To K, Takeshita H, Hidaka S, Nagayasu T
Hepato-gastroenterology 61 ( 134 ) 1739 - 1743 2014.9
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Recruitment of Young Medical Apprentices (RYOMA) project: a comprehensive surgical education program at a local academic institute in Japan.
Nanashima A, Hidaka S, Nonaka T, Yamasaki N, Tsuchiya T, Matsumoto K, Miyazaki T, Hatachi G, Sumida Y, Sawai T, Yasutake T, Nagayasu T
Journal of surgical education 71 ( 4 ) 587 - 92 2014.7
Language：Japanese Publishing type：Research paper (scientific journal)
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ABCC11/MRP8 Expression in the Gastrointestinal Tract and a Novel Role for Pepsinogen Secretion.
Matsumoto H, Tsuchiya T, Yoshiura K, Hayashi T, Hidaka S, Nanashima A, Nagayasu T
Acta histochemica et cytochemica 47 ( 3 ) 85 - 94 2014.6
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Nanashima A., Abo T., Murakami G., Tominaga T., Takeshita H., Hidaka S., Kunizaki M., Matsumoto H., To K., Miyazaki T., Tsuchiya T., Yamasaki N., Nagayasu T.
Hepato-gastroenterology 61 ( 131 ) 727 - 731 2014.5
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Hepato-gastroenterology
BACKGROUND/AIMS: To clarify improvement of hepatic resection in the recent years, we examined surgical records of 544 patients who underwent hepatectomy in 3 periods between 1994 and 2011 at a single academic institute. METHODOLOGY: Subjects were divided into 3 groups: group 1 (1994-1999, n = 156), group 2 (2000-2006, n = 228) and group 3 (2007-2011, n = 160). Clinical factors, surgical records and post-hepatectomy outcomes during hospitalization were compared between groups. RESULTS: In group 3, patient age was significantly higher and the incidences of alcoholic or fatty liver and obstructive jaundice were significantly higher than in group 1 (p < 0.05). Preoperative liver function was not different between groups, and only prothrombin activity was significantly better in group 1 in comparison with the other groups (p < 0.05). In comparison with group 1, the incidence of resident surgeons as the main operator were significantly higher than in group 3 (p < 0.01). Incidences of laparoscopic hepatectomy and thoraco-abdominal approach were increased in group 3 (p < 0.01). Incidences of combined organ and major vessels resections were significantly higher in group 3 in comparison with group 1 (p < 0.01). Use of omental wrapping and hemostatic devices were significantly more frequent in group 3 than in group 1 (p < 0.01). Surgical records were not different between groups but the red cell transfusion rate in group 3 was significantly lower than in group 1 (p < 0.05). Hospital stay in group 3 was significantly shorter than in group 1. Incidence of hepatectomy-related complication, particularly bile leakage, was significantly lower in group 3 than in group 1 (p < 0.05). CONCLUSIONS: According to this evaluation of different time periods, surgical outcomes have been improved with new surgical procedures and perioperative management.
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Improvement of Surgical Records and Outcomes after Hepatectomy at a Single Academic Institute in Japan.
Nanashima A, Abo T, Murakami G, Tominaga T, Takeshita H, Hidaka S, Kunizaki M, Matsumoto H, To K, Miyazaki T, Tsuchiya T, Yamasaki N, Nagayasu T
Hepato-gastroenterology 61 ( 131 ) 727 - 31 2014.5
Language：Japanese Publishing type：Research paper (scientific journal)
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Future prospects for tissue engineered lung transplantation: decellularization and recellularization-based whole lung regeneration.
Tsuchiya T, Sivarapatna A, Rocco K, Nanashima A, Nagayasu T, Niklason LE
Organogenesis 10 ( 2 ) 196 - 207 2014.4
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High expression of dihydropyrimidine dehydrogenase in lung adenocarcinoma is associated with mutations in epidermal growth factor receptor: implications for the treatment of non--small-cell lung cancer using 5-fluorouracil.
Mochinaga K, Tsuchiya T, Nagasaki T, Arai J, Tominaga T, Yamasaki N, Matsumoto K, Miyazaki T, Nanashima A, Hayashi T, Tsukamoto K, Nagayasu T
Clinical lung cancer 15 ( 2 ) 136 - 144.e4 2014.3
Language：Japanese Publishing type：Research paper (scientific journal)
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How to access photodynamic therapy for bile duct carcinoma.
Nanashima A, Isomoto H, Abo T, Nonaka T, Morisaki T, Arai J, Takagi K, Ohnita K, Shoji H, Urabe S, Senoo T, Murakami G, Nagayasu T
Annals of translational medicine 2 ( 3 ) 23 2014.3
Language：Japanese Publishing type：Research paper (scientific journal)
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Successful Colectomy for Hemorrhagic Colitis with Hemolytic Uremic Syndrome and Acute Encephalopathy due to Escherichia coli O157 Infection.
Tominaga T, Oikawa M, Takeshita H, Kunizaki M, Tou K, Abo T, Hidaka S, Nanashima A, Sawai T, Nagayasu T
Case reports in gastroenterology 8 ( 1 ) 82 - 8 2014.1
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Associated factors with surgical site infections after hepatectomy: predictions and countermeasures by a retrospective cohort study.
Nanashima A, Arai J, Oyama S, Ishii M, Abo T, Wada H, Takagi K, Tsuchiya T, Nagayasu T
International journal of surgery (London, England) 12 ( 4 ) 310 - 4 2014
Language：Japanese Publishing type：Research paper (scientific journal)
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A case of intestinal endometriosis with lymphovascular invasion
Tominaga T., Fukuda D., Takeshita H., To K., Abo T., Hidaka S., Nanashima A., Kinoshita N., Nagayasu T., Sawai T.
Japanese Journal of Gastroenterological Surgery 47 ( 6 ) 351 - 356 2014
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Japanese Journal of Gastroenterological Surgery
Endometriosis is a rare disorder characterized by the presence of endometrial mucosa abnormally implanted in locations other than the uterine cavity. A 38-year-old woman who was admitted after complaining of abdominal pain and abdominal distention for three months underwent abdominal CT which revealed a tumor in the ileocecal area. Abdominal pain occurred during the menstrual cycle. Laboratory data revealed elevation of CA125. We performed ileocecal resection. Pathologically, ileocecal endometriosis with lymphovascular involvement was diagnosed. This case of intestinal endometriosis suggested lymhogenic progression. © 2014 The Japanese Society of Gastroenterological Surgery.
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Nanashima A., Abo T., Takagi K., Arai J., To K., Kunizaki M., Hidaka S., Takeshita H., Sawai T., Nagayasu T.
European Journal of Surgical Oncology 40 ( 11 ) 1540 - 1549 2014
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：European Journal of Surgical Oncology
© 2014 Elsevier Ltd. All rights reserved. Background: Prognostic influences of hepatic transection by an anterior approach using the liver hanging maneuver (LHM) has not been fully clarified. Methods: We examined 233 patients who underwent major hepatectomy with the LHM (n = 75; hepatocellular carcinoma (HCC) in 35, colorectal liver metastasis (CLM) in 10, intrahepatic cholangiocarcinoma (ICC) in 14 and perihilar bile duct carcinoma (BDC) in 16) or without it (n = 158; HCC in 78, CLM in 21, ICC in 31 and BDC in 28). Results: In HCC patients, cancer-positive margin rate, blood loss, transection time and prevalence of posthepatectomy ascites in the LHM group were significantly lower than those in the non-LHM group (p < 0.05). In CLM, transection time in the LHM group was significantly lower than that in the non-LHM group (p < 0.05). In BDC patients, amount of blood loss, transection time and prevalence of ascites in the LHM group were significantly lower than those in the non-LHM group (p < 0.05). In CLM patients, tumor recurrence rate in the non-LHM group was significantly higher than that in the LHM group and disease-free survival in the LHM group was significantly better than that in the non-LHM group in CLM patients and, however, this difference was not observed in a large CLM exceeding 5 cm. However, significant differences of posthepatectomy disease-free and overall survivals were not observed in HCC, ICC and BDC patients. Conclusions: Although advantages of LHM improving surgical records in major anatomical liver resections were clarified, oncological advantages in the long-term survival of LHM was still uncertain in the hepatobiliary malignancies.
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To K., Takeshita H., Wakata K., Tominaga T., Kunizaki M., Abo T., Hidaka S., Nanashima A., Sawai T., Nagayasu T., Oka T.
Acta Medica Nagasakiensia 59 ( 3 ) 103 - 106 2014
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Acta Medica Nagasakiensia
© 2015, Nagasaki University School of Medicine. All rights reserved. Endoscopic submucosal dissection (ESD) is a standard treatment for early gastric cancer, but it is not generally used for colorectal lesions because of its high risk of adverse events. An unanticipated adverse event of rectal ESD is reported. A 71-year-old man was found to have a laterally spreading tumor at the upper rectum. ESD was performed. During the ESD, rectal perforation occurred, and emergency laparoscopic surgery was performed. At the operation, rectal perforation with retroperitoneal emphysema was detected. Surprisingly, an 8-cm-long, lacerated wound was found at the cecum wall. It was thought to have been caused by heat injury due to ESD. The perforated site was resected, and the laceration of the cecum was repaired by extracorporeal suture. In patients with perforation during ESD, it is essential to keep in mind that other organs might have heat-induced injury, and the patient should be more carefully followed.