Papers - KITAMURA Kazuo
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Paucity of CD34-positive cells and increased expression of high-mobility group box 1 in coronary thrombus with type 2 diabetes mellitus.「"jointly worked"」 Reviewed
Yamashita A, Nishihira K, Matsuura Y, Ito T, Kawahara K, Hatakeyama K, Hashiguchi T, Maruyama I, Yagi H, Matsumoto M, Fujimura Y, Kitamura K, Shibata Y, Asada Y
Atherosclerosis 224 ( 2 ) 511 - 514 2012.7
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1016
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Different distribution of pentraxin 3 and C-reactive protein in coronary atherosclerotic plaques.「"jointly worked"」 Reviewed
Matsuura Y, Hatakeyama K, Imamura T, Tsuruda T, Shibata Y, Kodama T, Kitamura K, Asada Y
J Atheroscler Thromb 19 ( 9 ) 837 - 845 2012.7
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.5551
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Comparison of the effects of intravenous methylprednisolone pulse versus oral prednisolone therapies on the first attack of minimal-change nephrotic syndrome in adults. 「"jointly worked"」 Reviewed
Fukudome K, Fujimoto S, Sato Y, Kitamura K
Nephrology (Carlton) 17 ( 3 ) 263 - 268 2012.5
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1111
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Characterization of the single transmembrane domain of human receptor activity-modifying protein 3 in adrenomedullin receptor internalization. 「"jointly worked"」 Reviewed
Kuwasako K, Kitamura K, Nagata S, Nozaki N, Kato J
Biochem Biophys Res Commun 420 ( 3 ) 582 - 587 2012.5
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1016
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Effects of proangiotensin-12 infused continuously over 14days in conscious rats.「"jointly worked"」 Reviewed
Komatsu Y, Kida N, Nozaki N, Kuwasako K, Nagata S, Kitamura K, Kato J
Eur J Pharmacol 683 ( 1 ) 186 - 189 2012.5
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1016
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The third extracellular loop of the human calcitonin receptor-like receptor is crucial for the activation of adrenomedullin signalling. 「"jointly worked"」 Reviewed
Kuwasako K, Hay DL, Nagata S, Hikosaka T, Kitamura K, Kato J
Brit J Pharmacol 166 ( 1 ) 137 - 150 2012.5
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1111
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GABAergic Inhibition Regulates Developmental Synapse Elimination in the Cerebellum Reviewed
Nakayama H., Miyazaki T., Kitamura K., Hashimoto K., Yanagawa Y., Obata K., Sakimura K., Watanabe M., Kano M.
Neuron 74 ( 2 ) 384 - 396 2012.4
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：Neuron
Functional neural circuit formation during development involves massive elimination of redundant synapses. In the cerebellum, one-to-one connection from excitatory climbing fiber (CF) to Purkinje cell (PC) is established by elimination of early-formed surplus CFs. This process depends on glutamatergic excitatory inputs, but contribution of GABAergic transmission remains unclear. Here, we demonstrate impaired CF synapse elimination in mouse models with diminished GABAergic transmission by mutation of a single allele for the GABA synthesizing enzyme GAD67, by conditional deletion of GAD67 from PCs and GABAergic interneurons or by pharmacological inhibition of cerebellar GAD activity. The impaired CF synapse elimination was rescued by enhancing GABA A receptor sensitivity in the cerebellum by locally applied diazepam. Our electrophysiological and Ca 2+ imaging data suggest that GABA A receptor-mediated inhibition onto the PC soma from molecular layer interneurons influences CF-induced Ca 2+ transients in the soma and regulates CF synapse elimination from postnatal day 10 (P10) to around P16. Nakayama et al. find that GABAergic inhibition onto Purkinje cell somata from molecular layer interneurons suppresses climbing fiber-induced Ca 2+ transients and regulates elimination of redundant climbing fiber inputs during postnatal cerebellar development. © 2012 Elsevier Inc.
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Three-year safety and effectiveness of fixed-dose losartan/hydrochlorothiazide combination therapy in Japanese patients with hypertension under clinical setting (PALM-1 Extension Study).「"jointly worked"」 Reviewed
Kita T, Yokota N, Ichiki Y, Ayabe T, Etoh T, Tamaki N, Kato J, Eto T, Kitamura K
Clin Exp Hypertens 34 ( 7 ) 498 - 503 2012.4
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.3109
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Inhibition of development of abdominal aortic aneurysm by glycolysis restriction.「"jointly worked"」 Reviewed
Tsuruda T, Hatakeyama K, Nagamachi S, Sekita Y, Sakamoto S, Endo GJ, Nishimura M, Matsuyama M, Yoshimura K, Sato Y, Onitsuka T, Imamura T, Asada Y, Kitamura K
Arterioscler Thromb Vasc Biol 32 ( 6 ) 1410 - 1417 2012.4
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1161
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メタボリックシンドローム対策としての特定健診の有用性?清武町研究―．（共著） Reviewed
野崎尚美,木田信章,桑迫健二,北村和雄,加藤丈司
宮崎県医師会医学会誌 36 ( 1 ) 14 - 18 2012.3
Language：Japanese Publishing type：Research paper (scientific journal)
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Plasma and tissue concentrations of proangiotensin-12 in rats treated with inhibitors of the renin-angiotensin system.「"jointly worked"」 Reviewed
Nagata S, Kato J, Kuwasako K, Asami M, Kitamura K
Hypertens Res 35 ( 2 ) 234 - 238 2012.2
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.1038
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管理不良高血圧患者に対するロサルタンからロサルタン／ヒドロクロロチアジド配合薬への切り替えによる長期（３年間）の降圧効果と安全性：PALM-1 extension研究．（共著） Reviewed
北 俊弘,横田直人,市来能成,綾部隆夫,江藤琢磨,玉置 昇,加藤丈司,江藤胤尚,北村和雄
Progress in Medicine 32 ( 2 ) 117 - 121 2012.2
Language：Japanese Publishing type：Research paper (scientific journal)
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Tonsillectomy delays progression of advanced IgA nephropathy to end-stage kidney disease.「"jointly worked"」 Reviewed
Komatsu H, Fujimoto S, Kikuchi M, Sato Y, Kitamura K
Ren Fail 34 ( 4 ) 448 - 453 2012.1
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.3109
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Sarcoidosis manifesting as cardiac sarcoidosis and massive splenomegaly. 「"jointly worked"」 Reviewed
Kawano S, Kato J, Kawano N, Yoshimura Y, Masuyama H, Fukunaga T, Shimao Y, Mihara K, Ueda A, Toyoda K, Imamura T, Kitamura K
Intern Med 51 ( 1 ) 65 - 69 2012.1
Language：English Publishing type：Research paper (scientific journal)
DOI： 10.2169
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心血管機能を制御するG蛋白共役型受容体の新たな分子調節機構と役割の解明．（共著） Reviewed
桑迫健二,北村和雄,永田さやか,加藤丈司
医科学応用研究財団研究報告 29 226 - 229 2012.1
Language：Japanese Publishing type：Research paper (other academic)
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Postinfarction dissecting intramyocardial haematoma in a patient treated with immunosuppressant Reviewed
Sakata K., Tsuruda T., Imamura T., Kitamura K.
BMJ Case Reports 32 ( 1 ) 2012
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：BMJ Case Reports
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アンジオテンシンII産生におけるプロアンジオテンシン-12の役割 Reviewed
永田さやか、桑迫健二、北村和雄
日本内分泌学会雑誌 88 ( 1 ) 340 - 340 2012
Publishing type：Research paper (scientific journal)
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アドレノメデュリンの診断薬・治療薬としての可能性 Reviewed
北村和雄
日本内分泌学会雑誌 88 ( 2 ) 797 - 797 2012
Publishing type：Research paper (scientific journal)
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両腕の血圧差と血管疾患および死亡のリスク Reviewed
北俊弘、北村和雄
血圧 19 ( 10 ) 854 - 855 2012
Publishing type：Research paper (scientific journal)
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糖尿病合併高血圧と血圧日内変動 Reviewed
北俊弘、北村和雄
血圧 19 ( 4 ) 344 - 345 2012
Publishing type：Research paper (scientific journal)