論文 - 北村 和雄
-
ARB/利尿薬合剤の降圧効果と安全性 査読あり
北俊弘、北村和雄
血圧 17 ( 12 ) 1028 - 1032 2010年
掲載種別：研究論文（学術雑誌）
-
大腸MALT lymphoma術後11年目にdiffuse large B cell lymphomaを認めた一例 査読あり
中島孝治、彦坂ともみ、星子新理、松本英丈、芦塚伸也、早稲田文子、押川勝太郎、稲津東彦、北村和雄、岩切太幹志、丸塚浩助
日本消化器病学会雑誌 107 ( suppl-2.2 ) 827 - 827 2010年
掲載種別：研究論文（学術雑誌）
-
メタボリック症候群とペントラキシン3 査読あり
小川恒夫、今村卓郎、北村和雄
生物試料分析 33 ( 4 ) 339 - 346 2010年
掲載種別：研究論文（学術雑誌）
-
Uchiyama S., Goto S., Matsumoto M., Nagai R., Origasa H., Yamazaki T., Shigematsu H., Shimada K., Yamada N., Bhatt D.L., Steg P.G., Ikeda Y.
Journal of the Neurological Sciences 287 ( 1-2 ) 45 - 51 2009年12月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Journal of the Neurological Sciences
The REduction of Atherothrombosis for Continued Health (REACH) Registry is a large, international, prospective cohort of patients with atherothrombosis or multiple (≥ 3) risk factors (MRFs) for atherothrombosis. Japanese patients (n = 5193) were enrolled into the REACH registry between August and December 2004. One-year event rate in patients with cerebrovascular disease (CVD) was compared with that of patients with symptomatic atherothrombosis at other locations. After one year (n = 5021), patients with CVD (n = 1962) experienced a higher rate of non-fatal strokes than patients with coronary artery disease (CAD), peripheral artery disease (PAD) or MRFs alone (2.77% vs. 1.28%, 2.07% and 1.56%, respectively), but a lower rate of non-fatal myocardial infarction (0.45% vs. 1.31%, 0.77% and 0.66%, respectively). Patients with CVD plus disease in ≥ 1 other vascular bed had higher rates of cardiovascular events than patients with CVD alone. Overall, event rates including non-fatal stroke, non-fatal myocardial infarction and cardiovascular death were higher for patients with CVD and PAD than for patients with CVD and CAD. Asymptomatic carotid stenosis ≥ 70% and ankle-brachial index < 0.9 were significant predisposing factors for stroke. Patients with CVD and co-existing atherothrombotic diseases had a high risk of recurrent events, including events arising in other vascular beds than originally diagnosed. © 2009 Elsevier B.V.
-
Adrenomedullin treatment reduces intestinal inflammation and maintains epithelial barrier function in mice administered dextran sulphate sodium. "jointly worked" 査読あり
Ashizuka S, Inagaki-Ohara K, Kuwasako K, Kato J, Inatsu H, Kitamura K
Microbiol Immunol 53 ( 10 ) 573 - 581 2009年10月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
Yamashita A., Matsuda S., Matsumoto T., Moriguchi-Goto S., Takahashi M., Sugita C., Sumi T., Imamura T., Shima M., Kitamura K., Asada Y.
Atherosclerosis 206 ( 2 ) 418 - 426 2009年10月
記述言語：日本語 掲載種別：研究論文（学術雑誌） 出版者・発行元：Atherosclerosis
Arterial thrombosis occurs in atherosclerotic, but rarely in non-atherosclerotic arteries. The present study investigates how hyperlipidemic condition affects thrombus formation on macrophage-rich neointima or normal intima in rabbits. Rabbits were fed with a 0.5% cholesterol diet, and then the femoral artery on one side of each rabbit was injured with a balloon catheter. Three weeks later, bilateral femoral arteries were similarly injured with a balloon catheter to produce thrombi on neointima and normal intima. We compared the expression and activity of intimal tissue factor (TF) as well as thrombus size and composition between these femoral arteries. 0.5% cholesterol diet combined with a balloon injury induced macrophage-rich neointima in injured arteries. The whole blood coagulation activity or plasma thrombin generation activity did not differ after consuming the 0.5% cholesterol diet for 4 weeks, and an anti-TF antibody did not affect the measured parameters. TF activities were increased in the neointima/media compared with normal intima/media. Balloon injury induced large platelet-fibrin thrombi on macrophage-rich neointima, whereas small platelet thrombi were produced in normal arteries even under hyperlipidemic conditions. Recombinant human tissue factor pathway inhibitor (25 μg/(kg min)) and argatroban (100 μg/(kg min)), a specific thrombin inhibitor, significantly reduced thrombus formation on induced neointima, but not on normal intima. Thrombin generation mediated by TF in intima contributes to thrombus formation on macrophage-rich neointima, but not on normal intima. The TF content in disrupted atherosclerotic plaques might play a more important role than hyperlipidemia in the development of atherothrombosis. © 2009 Elsevier Ireland Ltd. All rights reserved.
-
Increased plasma levels of the mature and intermediate forms of adrenomedullin in obesity. "jointly worked" 査読あり
Nomura I, Kato J, Tokashiki M, Kitamura K
Regulatory Peptides 158 ( (1-3) ) 127 - 131 2009年8月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
Pharmacological stimulation of soluble guanylate cyclase modulates hypoxia-inducible factor-1α in rat heart. "jointly worked" 査読あり
Tsuruda T, Hatakeyama K, Masuyama H, Sekita Y, Imamura T, Asada Y, Kitamura K
Tsuruda T, Hatakeyama K, Masuyama H, Sekita Y, Imamura T, Asada Y, Kitamura K 297 ( 4 ) 1274 - 1280 2009年8月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
Flow cytometric analysis of the calcitonin receptor-like receptor domains responsible for cell-surface translocation of receptor activity-modifying proteins. "jointly worked" 査読あり
Kuwasako K, Kitamura K, Nagata S, Kato J
Biochemical and Biophysical Research Communications 384 ( 2 ) 249 - 254 2009年6月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
Pressure-independent effects of pharmacological stimulation of soluble guanylate cyclase on fibrosis in pressure-overloaded rat heart. "jointly worked" 査読あり
Masuyama H, Tsuruda T, Sekita Y, Hatakeyama K, Imamura T, Kato J, Asada Y, Stasch JP, Kitamura K
Hypertension Research 32 ( 7 ) 597 - 603 2009年5月
記述言語：英語 掲載種別：研究論文（学術雑誌）
DOI： 10.1038/hr.2009.64
-
Association between body mass index and chronic kidney disease: a population-based, cross-sectional study of a Japanese community. "jointly worked" 査読あり
Nomura I, Kato J, Kitamura K
Nomura I, Kato J, Kitamura K 5 ( 1 ) 315 - 320 2009年4月
記述言語：英語 掲載種別：研究論文（学術雑誌）
DOI： 10.2147/vhrm.s5522
-
Interleukin-10 correlates with oxidized low density lipoprotein in coronary culprit plaques. "jointly worked" 査読あり
Nishihira K, Imamura T, Ishikawa T, Yamashita A, Shibata Y, Itabe H, Kitamura K, Asada Y
Thrombosis research 124 ( 3 ) 335 - 337 2009年3月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy. "jointly worked" 査読あり
Ferrario CM, Varagic J, Habibi J, Nagata S, Kato J, Chappell MC, Trask AJ, Kitamura K, Whaley-Connell A, Sowers JR
Am J Physiol Heart Circ Physiol 296 ( 4 ) 1184 - 1192 2009年2月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
Effects of uroguanylin on natriuresis in experimental nephrotic rats. "jointly worked" 査読あり
Baba A, Fujimoto S, Kikuchi M, Kita T, Kitamura K
Nephrology 14 ( 1 ) 80 - 85 2009年2月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
Recent therapeutic strategies improve renal outcome in patients with IgA nephropathy. "jointly worked" 査読あり
Komatsu H, Fujimoto S, Hara S, Fukuda A, Fukudome K, Yamada K, Sato Y, Kitamura K
American Journal of Nephrology 30 ( 1 ) 19 - 25 2009年1月
記述言語：英語 掲載種別：研究論文（学術雑誌）
DOI： 10.1159/000197116
-
Effect of adrenomedullin on the cerebral circulation: relevance to primary headache disorders. "jointly worked" 査読あり
Petersen KA, Birk S, Kitamura K, Olesen J
Petersen KA, Birk S, Kitamura K, Olesen J 29 ( 1 ) 23 - 30 2009年1月
記述言語：英語 掲載種別：研究論文（学術雑誌）
-
Minimal change nephrotic syndrome complicated with recurrence of malignant thymoma: an interesting case with remission due to steroid therapy of both nephrotic syndrome and thymoma] 査読あり
Akihiro Fukuda 1, Yuji Sato, Shuji Iwatsubo, Hiroyuki Komatsu, Ryousuke Nishiura, Keiichi Fukudome, Kazuhiro Yamada, Seiichiro Hara, Shouichi Fujimoto, Kazuo Kitamura
Nihon Jinzo Gakkai Shi 51 ( 2 ) 130 - 137 2009年
掲載種別：研究論文（学術雑誌）
-
食塩摂取量の変化に伴う血中と組織中プロアンジオテンシン-12(proang-12)およびレニン・アンジオテンシン(RA)系因子の変化 査読あり
永田さやか、加藤丈司、北村和雄
日本内分泌学会雑誌 85 ( 1 ) 374 - 374 2009年
掲載種別：研究論文（学術雑誌）
-
地域住民における血中アルドステロンとbody mass index(BMI)およびインスリン値との関連 査読あり
野村郁夫、加藤丈司、北村和雄
日本内分泌学会雑誌 85 ( 2 ) 716 - 716 2009年
掲載種別：研究論文（学術雑誌）
-
話題のホルモン・受容体・酵素: 最近の知見から アドレノメデュリン(AM), PAMPとその受容体 査読あり
北村和雄
Heart View 13 ( 12 ) 69 - 75 2009年
掲載種別：研究論文（学術雑誌）